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Herbal Care

Can Anise Cure What Ails You?

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The licorice-flavored herb anise contains high levels of health-boosting compounds called phenylpropanoids.

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A team of researchers isolated 22 compounds in anise essential oils, and found some phenylpropanoid compounds that were unique to anise, and four of the compounds had never before been identified in any plant.

Aside from effectively controlling aphids and the plant fungus Colletotrichum, the compounds also showed promise for human health problems. Specifically, some of the compounds were effective against:

Plasmodium falciparum, the parasite that causes malaria in humans.
Mycobacterium intracellulare, a bacterium that can cause illness in people with compromised immune systems.
Further, some phenylpropanoids had anti-inflammatory and phytoestrogen properties.

The researchers suggested that compounds in anise essential oils may be useful for developing pharmaceuticals and agrochemicals.
Sources:
Science Daily March 12, 2008
Pure and Applied Chemistry 2007, Vol. 79, No. 4, pp. 539-556

Categories
News on Health & Science

How Viruses Become Infectious

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Biologists have mapped how a deadly class of viruses including dengue, West Nile, yellow fever and encephalitis become infectious in a pair of studies published in the journal Science .

“This is possibly the most detailed understanding of how any virus matures,” said study author Michael Rossmann of Purdue University in Indiana.

Rossmann and his colleagues detailed critical structural changes that take place as the dengue virus moves from the inner to the outer portions of its host cell.

The findings pertain to all viruses in the family of flaviviruses which are carried by mosquitoes and ticks.

They found that a protein which coats the genome of the virus particle undergoes large changes in its structure so that it becomes capable of fusing with cell membranes.

This structural change, which occurs as the virus is being secreted from its host, allows the protein to infect other cells rather than attaching itself to its host.

“It’s like a bird being pushed out of the nest and suddenly being able to fly,” Rossmann said in a telephonic interview.

This transformation occurs as the virus is exposed to progressively less acidic conditions which change the protein structure in its outer shell.

“This change in acidity was already known, but its impact on the maturation process was not known until these new findings,” Rossmann said.

This discovery could help researchers develop an antiviral treatment for dengue fever, which infects more than 50 million people and kills about 24,000 each year.

“There are a number of places where small drug compounds might interfere with the changes which we describe,” he said.

A vaccine has not yet been developed for dengue fever because multiple exposures can actually increase the risk of developing the more deadly dengue hemorrhagic fever.

Sources: The Times Of India

Categories
News on Health & Science

Survival Of The Most Resistant

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Indian farmers do not follow guidelines while cultivating genetically modified crops, exposing them to the danger of pesticide resistance.

Pesticides and resistance are like summer and winter, one following the other with inevitability. When genetic engineering was invented, it gave the farmer some respite from the perpetual cycle of pesticide use and pesticide resistance in insects. After more than a decade of widespread use, genetically engineered crops seemed to be holding their own against the insects, despite some stray reports to the contrary. Now a US researcher says that resistance is indeed developing in some insects, with important ramifications for Indian cotton farmers.

Bruce Tabashnik, professor at the department of entomology at the University of Arizona, analysed all the field data from the last 10 years in four countries: Australia, Spain, China and the US. He focused on one gene, the so-called Cry1Ac. This gene produces a protein that is toxic to some pests that attack cotton and corn. Tabashnik found that resistance has increased substantially in one pest, but not in others.

“It is the natural process of evolution,” says Tabashnik. The development of resistance in other pests was delayed because of other tactics to control them.

The gene Cry1Ac is derived from a bacterium called Bacillus thuringiensis. This bacterium was discovered in the early 20th century. It has several genes that code for proteins that are toxic to insects, and Cry1Ac is only one of them. The bacterium was being used as sprays to kill pests in the 1960s.

By the 1980s, when pesticide resistance became a problem and genetic engineering techniques were developed, agri-biotech companies transferred the toxic genes to crops like cotton, corn and potato. If the larvae of the pests ate this plant, they would die immediately. The first genetically engineered cotton variety was planted in the US in 1996.

Since 1996, Bt cotton and corn have been grown in 162 million hectares around the world. Such large areas over 10 years provide enough opportunity for insects to grow resistant, unless measures are taken to slow its development. Farmers who grow genetically engineered, insect-resistant crops are asked to maintain a refuge: a separate region where they grow crops that are susceptible to insects. In all developed countries, farmers maintain a refuge. However, such a practice is not strictly adhered to in India, thus giving the pests more opportunities to develop resistance.

Laboratory studies have shown that pests indeed develop resistance quickly to Bt genes. However, lab experiments do not prove much beyond the principle of natural selection. “It is very easy for pests to evolve resistance in the lab,” says Tabashnik. Evolution of resistance in the field, while also being inevitable in the long run, is a more serious matter because farmers practise methods that delay the development of resistance.

Tabashnik and his colleagues did not do any field experiment for this study. Instead they analysed data from peer reviewed journals, provided they met some criteria. The most important of these criteria is the inclusion of data about concurrently tested susceptible strains of pests. Data from India were ignored for this reason; it did not include concurrent data about susceptible strains.

Tabashnik analysed the emergence of resistance in six major strains of pests. Of these, he found resistance developing in only one strain, Helicoverpa zea. Resistance to the Cry1Ac gene has developed in this strain of pest in the US, particularly in the states of Arkansas and Mississippi. However, this resistance has not caused any crop losses for two reasons. One, farmers had used some pesticide as well to control pests. Second, the crop had killed 40-60 per cent of the pests even when they were resistant.

What do these results mean for India? “The data for India were ambiguous,” says Tabashnik. This does not mean that resistance to the Bt gene has not developed among cotton pests in India.

“Indian farmers do not strictly adhere to the methods to be employed while cultivating transgenic (with genes from another species) crops,” says K.K. Narayanan, managing director of Metahelix, an agri-biotech company in Bangalore.

US farmers escaped damage from resistant pests because of good pest control practices. Are Indian farmers listening?

Sources: The Telegraph (Kolkata, India)

Categories
News on Health & Science

Pesticide Parkinson’s Link Strong

There is strong evidence that exposure to pesticides significantly increases the risk of Parkinson’s disease, experts believe.

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Parkinson’s can lead to difficulty in moving arms and legs

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It comes as another study, published in the BMC Neurology journal, has made the link to the neurological disease.

The US researchers found those exposed to pesticides had a 1.6 times higher risk after studying 600 people.

Experts said it was now highly likely pesticides played a key role – albeit in combination with other factors.

The disorder, which normally develops later in life and can affect movement and talking, is also influenced by genetic factors.

Several gene defects have been identified, but these are thought to be rare and only account for a small proportion of the 120,000 people affected by the disease in the UK.

The US team, which involved scientists from Duke University, Miami University and the Udall Parkinson’s Disease Research Center of Excellence, quizzed 319 patients about their pesticide use.

The answers were compared to over 200 family members and other controls who did not have the disease.

Related individuals were chosen as they would share many environmental and genetic backgrounds in a bid to isolate the impact of the pesticides.

They found those exposed to pesticides had a 1.6 times greater risk of developing the disease.

Heavy use, classed as over 200 days exposure over a lifetime, carried over double the risk.

And the study also revealed herbicides and insecticides were the pesticides most likely to increase risk.

Key role

Lead researcher Dana Hancock said: “I think there is very strong evidence now linking the two. What we need to find out how – the biological process.

“What we noticed in our research was that recreational pesticide use in the home and garden was more of a source of exposure than occupational use.”

Kieran Breen, director of research at the Parkinson’s Disease Society, said the link had been recognised by earlier studies, but this study “strengthened the fact that pesticides play a key role”.

However, he added: “We still don’t know exactly what causes Parkinson’s. It’s most likely to be a combination of genetic susceptibility and environmental factors.”

He pointed out a survey of 10,000 patients by the charity had revealed only one in 10 had had long-term exposure to pesticides.

“We still don’t know exactly what causes Parkinson’s “says Kieran Breen, of the Parkinson’s Disease Society

Click to see also:->
Pesticide use link to Parkinson’s
Pesticide link to Parkinson’s
Vitamin E cuts Parkinson’s risk
Parkinson’s Disease

Sources: BBC NEWS:28Th. March.’08

Categories
Ailmemts & Remedies

Taste Disorders

Definition:
We experience taste when a substance contacts one of four taste receptor cells for sweet, salt, bitter, or sour. The receptor cells are located in taste buds spread over the surface of the tongue and throat. Three different nerves allow us to taste, therefore it is very difficult to lose all sense of taste through a nerve injury. In addition, like the smell nerves, the taste receptor cells are replaceable and if damaged they can grow back. A decrease in ability to taste is called hypogeusia, and a total loss of taste is termed ageusia.

CLICK & SEE THE PICTURES

Click to learn:-> What is taste Description of the parts of the tongue.

Taste disorders like smell disorders can occur for many different reasons. Total loss of taste often indicates a disorder throughout the body such as due to toxicity, medications, or nutrition disorders. Decreased or abnormal taste can also occur from poor dentition or from cancer of the mouth.

Besides a detailed history and head and neck exam, evaluation by an otolaryngologist for smell and taste disorders may add smell and taste testing. Testing of smell function often includes taking a “scratch and sniff” odor identification test matching a smell with a list of odors. Taste function can be tested by applying four different solutions (sweet, salt, bitter, and sour) to four different regions of the tongue. Additional evaluation may include a CT scan and/or an MRI of the brain and sinuses.

If you experience a taste problem, it is important to remember that you are not alone. More than 200,000 people visit a physician for such a chemosensory problem each year. Many more taste disorders go unreported.

Many people who have taste disorders also notice problems with their sense of smell. If you would like more information about your sense of smell, the fact sheet Smell Disorders may answer some of your questions.

How does our sense of taste work?

Taste belongs to our chemical sensing system, or the chemosenses. The complex process of tasting begins when tiny molecules released by the substances around us stimulate special cells in the nose, mouth, or throat. These special sensory cells transmit messages through nerves to the brain, where specific tastes are identified

Click to learn more:->Smell and Taste Disorders

Gustatory or taste cells react to food and beverages. These surface cells in the mouth send taste information to their nerve fibers. The taste cells are clustered in the taste buds of the mouth, tongue, and throat. Many of the small bumps that can be seen on the tongue contain taste buds.

Another chemosensory mechanism, called the common chemical sense, contributes to appreciation of food flavor. In this system, thousands of nerve endings–especially on the moist surfaces of the eyes, nose, mouth, and throat–give rise to sensations like the sting of ammonia, the coolness of menthol, and the irritation of chili peppers.

We can commonly identify at least five different taste sensations: sweet, sour, bitter, salty, and umami (the taste elicited by glutamate, which is found in chicken broth, meat extracts, and some cheeses). In the mouth, these tastes, along with texture, temperature, and the sensations from the common chemical sense, combine with odors to produce a perception of flavor. It is flavor that lets us know whether we are eating a pear or an apple. Some people are surprised to learn that flavors are recognized mainly through the sense of smell. If you hold your nose while eating chocolate, for example, you will have trouble identifying the chocolate flavor–even though you can distinguish the food’s sweetness or bitterness. That is because the distinguishing characteristic of chocolate, for example, what differentiates it from caramel, is sensed largely by its odor.

What are the taste disorders?

The most common true taste complaint is phantom taste perceptions. Additionally, testing may demonstrate a reduced ability to taste sweet, sour, bitter, salty, and umami, which is called hypogeusia. Some people can detect no tastes, called ageusia. True taste loss is rare; perceived loss usually reflects a smell loss, which is often confused with a taste loss.

Click to learn more about :->Test Disorders

In other disorders of the chemical senses, the system may misread and or distort an odor, a taste, or a flavor. Or a person may detect a foul taste from a substance that is normally pleasant tasting.

Symptoms – Taste disorders are often temporary. Alteration in taste varies depending upon the disease, period of suffering, treatment and drugs. For example:

  • In gout – uric acid diathesis/metabolism – salty taste

  • In infection (bacterial) – metallic taste

  • In fever (viral flu) – bitter taste

  • In gastritis/heartburn – sour taste

  • In toxicity – metallic taste

What causes taste disorders?

Some people are born with chemosensory disorders, but most develop them after an injury or illness. Upper respiratory infections are blamed for some chemosensory losses, and injury to the head can also cause taste problems.

Loss of taste can also be caused by exposure to certain chemicals such as insecticides and by some medicines. Taste disorders may result from oral health problems and some surgeries (e.g. third molar extraction and middle ear surgery). Many patients who receive radiation therapy for cancers of the head and neck develop chemosensory disorders.

How are taste disorders diagnosed?

The extent of a chemosensory disorder can be determined by measuring the lowest concentration of a chemical that a person can detect or recognize. A patient may also be asked to compare the tastes of different chemicals or to note how the intensity of a taste grows when a chemical’s concentration is increased.

Scientists have developed taste testing in which the patient responds to different chemical concentrations. This may involve a simple “sip, spit, and rinse” test, or chemicals may be applied directly to specific areas of the tongue.

Click to learn more :->How are taste and smell disorders diagnosed?

Are taste disorders serious?

Yes. A person with a taste disorder is challenged not only by quality-of-life issues, but also deprived of an early warning system that most of us take for granted. Taste helps us detect spoiled food or beverages and, for some, the presence of food to which we’re allergic. Perhaps more serious, loss of the sense of taste can also lead to depression and a reduced desire to eat.

Abnormalities in chemosensory function may accompany and even signal the existence of several diseases or unhealthy conditions, including obesity, diabetes, hypertension, malnutrition, and some degenerative diseases of the nervous system such as Parkinson’s disease, Alzheimer’s disease, and Korsakoff’s psychosis.

Complication:

  • Disgust for food/life

  • Malnutrition

  • Depression

Can taste disorders be treated?

Yes. If a certain medication is the cause of a taste disorder, stopping or changing the medicine may help eliminate the problem. Some patients, notably those with respiratory infections or allergies, regain their sense of taste when the illness resolves. Often the correction of a general medical problem can also correct the loss of taste. Occasionally, recovery of the chemosenses occurs spontaneously.

General treatment – Treatment usually depends upon the cause and nature of the disease(s). Getting normalcy will be aimed mostly at removing the exciting or maintaining causes, i.e. by

  • Correcting anaemia,allergies dental problems, uric acid diathesis, etc.

  • Treating mouth ulcers, infections (bacterial / viral / fungal), digestive or acid reflux disorders, etc.

  • Changing or stopping newly added medicines (antibiotics, anticonvulsants, antidepressants, pain-killers, etc.)

Commonly, if there is no serious illness, physicians will simply prescribe vitamin supplements and till taste recovers on its own (i.e., without providing any specific treatment).

Homeopathic approach on taste disorders – In all other system of medicines, the recovery of taste will come in the end i.e., after stopping the treatment process/medicines. Also, sometimes they need to leave the taste to come up on its own. Whereas while getting Homeopathy treatment, patients’ feelings and sensations get improved first. Well being sensations will always be the first improvement with successful treatment of Homeopathy. Homeopathy concentrates on each and every aspect of patient feelings and restores them to normal first (prior to setting right the disease). It works in all ways to raise immunity. For raising immunity/strengthen vitality, it enhances good intake of diet (by making the taste good). Thus here is another example to show Homeopathy is on the right track towards nature.

Some feel the distorted taste without any diseases or sufferings (with unknown or idiopathic causes) and some other suffers with incurable diseases. Here too, Homeopathy can succeed in correcting the taste with its individualisation treatment with characteristic symptoms of patient and disease with tongue indications and taste characters.

To spice up taste, Homeopathy can work amazingly. There are specific medicines for specific feelings of taste in Homeopathy, likewise for cravings and aversions too. They will act at the core of the disease and clear the tongue problems simultaneously.

For example:

  • Diminished taste – Borax, Carboveg, Cyclamen, Puls, Veratrum alb,

  • Complete loss of taste – Stramonium

  • Abnormal taste of foods (or water) – sweetish – Cuprum met, Merc sol, Veratrum Alb, etc.

  • Sweet metallic taste in mouth/tongue – Cocculus, Merc sol, etc.

  • Salty taste in mouth/tongue – Cyclamen, Iodium, Merc sol, Nat mur, etc.

  • Sour taste –Calc carb, China, Lycopodium, Nux vom, Rhus tox, Sulphur, etc.

  • Bitter taste – Borax, Bryonia, Carbo veg, China, Lachesis, Nat mur, Pulsatilla, Rhus tox, Stramonium, Sulphur, etc.

  • Soapy taste – Iodium

  • Bloody taste – Bovista & Kreosote

  • Coppery taste – Medorrhinum

  • Taste remains in tongue for a long time after eating – Hydrastis

  • Taste of rotten eggs – Cuprum met, Merc sol, Pulsatilla

  • Oily/greasy taste in tongue/mouth – Causticum, Rhus tox, Secale cor

  • Feeling numbness/tingling sensation in tongue – Aconite, Causticum, Coninum, Gelsemium, Nux vom, Nat mur, Secale cor, etc.

  • Burning tongue – Apis, Ars alb, Arum triphyllum, Baptisia, Belladonna, Beri Beri vul, Capsicum, Causticum, etc.

  • Sensation of hair in tongue – Kali bich, Alumina, Nat mur, etc.

  • Frothy saliva in mouth – Stramonium

These medicines should be taken under the advice and diagnosis of a Qualified Homeopath.

What research is being done?

The NIDCD supports basic and clinical investigations of chemosensory disorders at institutions across the Nation. Some of these studies are conducted at several chemosensory research centers, where scientists work together to unravel the secrets of taste disorders.

Some of the most recent research on our sense of taste focuses on identifying the key receptors in our taste cells and how they work in order to form a more complete understanding of the gustatory system, particularly how the protein mechanisms in G-protein-coupled receptors work. Advances in this area may have great practical uses, such as the creation of medicines and artificial food products that allow older adults with taste disorders to enjoy food again. Future research may examine how tastes change in both humans and animals. Some of this research will focus on adaptive taste changes over long periods in different animal species, while other research will examine why we accept or have an aversion to different tastes. Beyond this, scientists feel future gustatory research may also investigate how taste affects various processing activities in the brain. Specifically, how taste interacts with memory, influences hormonal feedback systems, and its role in the eating decisions and behavior.

Already, remarkable progress has been made in establishing the nature of changes that occur in taste senses with age. It is now known that age takes a much greater toll on smell than on taste. Also, taste cells (along with smell cells) are the only sensory cells that are regularly replaced throughout a person’s life span–taste cells usually last about 10 days. Scientists are examining these phenomena which may provide ways to replace damaged sensory and nerve cells.

NIDCD’s research program goals for chemosensory sciences include

* Promoting the regeneration of sensory and nerve cells
* Appreciating the effects of the environment (such as gasoline fumes, chemicals, and extremes of relative humidity and temperature) on taste.
* Preventing the effects of aging.
* Preventing infectious agents and toxins from reaching the brain through the olfactory nerve.
* Developing new diagnostic tests.
* Understanding associations between chemosensory disorders and altered food intake in aging as well as in various chronic illnesses.
* Improving treatment methods and rehabilitation strategies.

What can I do to help myself?

Proper diagnosis by a trained professional, such as an otolaryngologist, is important. These physicians specialize in disorders of the head and neck, especially those related to the ear, nose, and throat. Diagnosis may lead to treatment of the underlying cause of the disorder. Many types of taste disorders are curable, and for those that are not, counseling is available to help patients cope.

Where can I find more information?

NIDCD maintains a directory of organizations that can answer questions and provide printed or electronic information on taste disorders. Please see the list of organizations at www.nidcd.nih.gov/directory.

Use the following subject area to help you search for organizations that are relevant to taste disorders:

* Smell and Taste

For more information, additional addresses and phone numbers, or a printed list of organizations, contact:

NIDCD Information Clearinghouse
1 Communication Avenue
Bethesda, MD 20892-3456
Toll-free Voice: (800) 241-1044
Toll-free TTY: (800) 241-1055
Fax: (301) 770-8977
E-mail: nidcdinfo@nidcd.nih.gov

For more information, contact the NIDCD Information Clearinghouse.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Resources:
http://www.nidcd.nih.gov/health/smelltaste/taste.asp
http://www.meei.harvard.edu/patient/tasteandsmell.php
http://chennaionline.com/health/Homoeopathy/Aug2007/08homeo133.asp

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