Find Me A Cure

Definition:
A blepharospasm (from Greek: blepharo, eyelid, and spasm, an uncontrolled muscle contraction), is any abnormal tic or twitch of the eyelid.

It normally refers to Benign Essential Blepharospasm, a focal dystonia - a neurological movement disorder involving involuntary and sustained muscle contractions of the muscles around the eyes. Benign means the condition is not life threatening. Essential indicates that the cause is unknown, but fatigue, stress, or an irritant are possible contributing factors. Symptoms sometimes last for a few days then disappear without treatment, but in most cases the twitching is chronic and persistent, causing lifelong challenges. The symptoms are often severe enough to result in functional blindness. The person’s eyelids feel like they are clamping shut and will not open without great effort. Patients have normal eyes, but for periods of time are effectively blind due to their inability to open their eyelids.

Although strides have recently been made in early diagnosis, blepharospasm is often initially mis-diagnosed as allergies or “dry eye syndrome”. It is a fairly rare disease, affecting only one in every 20,000 people in the United States

Symptoms:

Most people develop blepharospasm without any warning symptoms. It may begin with a gradual increase in blinking or eye irritation. Some people may also experience fatigue, emotional tension, or sensitivity to bright light. As the condition progresses, the symptoms become more frequent, and facial spasms may develop. Blepharospasm may decrease or cease while a person is sleeping or concentrating on a specific task.

*Excessive blinking and spasming of the eyes, usually characterized by uncontrollable eyelid closure of durations longer than the typical blink reflex, sometimes lasting minutes or even hours.

*Uncontrollable tics or twitches of the eye muscles and surrounding facial area. Some sufferers have twitching symptoms that radiate into the nose, face and sometimes, the neck area.

*Dryness of the eyes

*Sensitivity to the sun and bright light

Causes:
What causes Blepharospasm is largely unknown, although some educated guesses are being made. In most cases, blepharospasm seems to develop spontaneously. Some blepharospasm patients have a previous history of dry eyes and/or light sensitivity, but others report no previous eye problems before onset of initial symptoms.

Blepharospasm is associated with an abnormal function of the basal ganglion from an unknown cause. The basal ganglion is the part of the brain responsible for controlling the muscles. In rare cases, heredity may play a role in the development of blepharospasm.

Concomitance with dry eye, as well as other dystonias such as Meige’s syndrome has been observed. Blepharospasms can be caused by concussions in some rare cases, when a blow to the back of the head damages the basal ganglia.

Some drugs can induce blepharospasm, such as those used to treat Parkinson’s disease, as well as sensitivity to hormone treatments, including Estrogen replacement therapy for women going through Menopause; blepharospasm can also be a symptom of acute withdrawal from benzodiazepine dependence.

Treatment:
*Drug therapy: Drug therapy for blepharospasm has proved generally unpredictable and short-termed. Finding an effective regimen for any patient usually requires trial and error over time. In some cases a dietary supplement of magnesium chloride has been found effective.

*Botulin toxin (Botox) injections have been used, to induce localized, partial paralysis. Among most sufferers, botox is the preferred treatment method. Injections are generally administered every three months, with variations based on patient response and usually give almost immediate relief (though for some it may take more than a week), from the spasming. Most patients can resume a relatively normal life with regular Botox treatments. A minority of sufferers get minimal or no result from Botox injections and have to find other treatments. For some, Botox diminishes in its effectiveness after many years of use. An observed side effect in a minority of patients is ptosis or eyelid droop. Attempts to inject in locations that minimise ptosis can result in diminished ability to control spasms.

*Surgery: Patients that do not respond well to medication or botulinum toxin injection are candidates for surgical therapy. The most effective surgical treatment has been protractor myectomy, the removal of muscles responsible for eyelid closure.

*Dark glasses are often worn because of sunlight sensitivity, as well as to hide the eyes from others.

*Stress management and support groups can help sufferers deal with the disease and prevent social isolation.

To date, there is no successful cure for blepharospasm, although several treatment options can reduce its severity.

In the United States and Canada, the injection of Oculinum (botulinum toxin, or Botox) into the muscles of the eyelids is an approved treatment for blepharospasm. Botulinum toxin, produced by the bacterium Clostridium botulinum, paralyzes the muscles of the eyelids.

Medications taken by mouth for blepharospasm are available but usually produce unpredictable results. Any symptom relief is usually short term and tends to be helpful in only 15 percent of the cases.

Myectomy, a surgical procedure to remove some of the muscles and nerves of the eyelids, is also a possible treatment option. This surgery has improved symptoms in 75 to 85 percent of people with blepharospasm.

Alternative treatments may include biofeedback, acupuncture, hypnosis, chiropractic, and nutritional therapy. The benefits of these alternative therapies have not been proven.

Click to see:->Blepharospasm Resource Guide from the National Eye Institute (NEI).

BEBRF: Benign Essential Blepharospasm Research Foundation

http://www.blepharospasm.org/forums/beb/index.html

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Resources:
http://en.wikipedia.org/wiki/Blepharospasm
http://www.nei.nih.gov/health/blepha/

1 Comment(s)

Comments RSS TrackBack Identifier URI

Leave a comment

Name (required)

Mail (will not be published) (required)

Website

If you liked the post, please subscribe to my RSS feed.
If we could help you, please spread the word.