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Herbs & Plants

Sida cordifolia

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Botanical Name : Sida cordifolia
Family: Malvaceae
Genus: Sida
Species: S. cordifolia
Kingdom: Plantae
Order: Malvales

Common Name :Bala, Country mallow, Heart-leaf sida or Flannel weed

English Name: Country Mallow
Hindi Name: Khareti, Bala, Barial, Kumghi.

Parts used: Root, bark, leaves, flowers and seeds.

Habitat :Sida cordifolia is native to India. It has naturalized throughout the world, and is considered an invasive weed in Africa, Australia, the southern United States, Hawaiian Islands, New Guinea, and French Polynesia. The specific name, cordifolia, refers to the heart-shaped leaf.

Description:
S. cordifolia is an erect perennial that reaches 50 to 200 cm (20 to 79 in) tall, with the entire plant covered with soft white felt-like hair that is responsible for one of its common names, “flannel weed”. The stems are yellow-green, hairy, long, and slender. The yellow-green leaves are oblong-ovate, covered with hairs, and 3.5 to 7.5 cm (1.4 to 3.0 in) long by 2.5 to 6 cm (0.98 to 2.4 in) wide. The flowers are dark yellow, sometimes with a darker orange center, with a hairy 5-lobed calyx and 5-lobed corolla.
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Flowers yellow, peduncles, axillary, jointed much above the panicles, upper flowers nearly sessile and fasciculate towards the tip of the branches forming subspicate inflorescence. Fruits subdiscoid, 6-8 mm across, mericarps 10, 3 sided. Seeds trigonous, glabours, tufted-pubescent near the hilum.

As a weed, it invades cultivated and overgrazed fields, competing with more desired species and contaminating hay.

Chemical constituents: Asparagin, alkaloids: ephedrine, hypaphorine, vasicinone, vasicine and vasicinol (Ghosal, Chauhan, and Mehta 1975), phytosterols, mucin, gelatin, potassium nitrate and rutin. Ephedrine content of whole plant is 0.085 %. The seeds contain 0.32% of alkaloid. A study reported 0.112% of ephedrine in whole plant of Sida cordifolia (Khatoon, Srivastava, Rawat and Mehrotra 2005). The seeds contain more alkaloids that that is found in the stems, roots or leaves.  Non-polar constituents have been reported from plant growing in Bangladesh (Khan, Rashid, Huq and Ahmad 1989).

No tannin or glycosides have been identified from the plant. The roots and stems contain the alkaloid ephedrine, normally observed in the different varieties of the gymnosperm genus Ephedra. Recent analyses have revealed that ephedrine and pseudoephedrine constitute the major alkaloids from the aerial parts of the plant, which also show traces of sitosterol and palmitic, stearic and hexacosanoic acids. The flavones: 5,7-dihydroxy-3-isoprenyl flavone (1) and 5-hydroxy-3-isoprenyl flavone (2), ?-sitosterol and stigmasterol have been isolated from the plant. The analgesic alkaloid (5?-Hydroxymethyl-1?-(1,2,3,9-tetrahydro-pyrrolo [2,1-b] quinazolin-1-yl)-heptan-1-one)has also been found. Sterculic, malvalic and coronaric acids have been isolated from the seed oil, along with other fatty acids (Chem. Ind. 1985. 483).

Medicinal Uses:
According to Ayurveda, the plant is tonic, astringent, emollient, aphrodisiac and useful in treatment of respiratory system related troubles. Bark is considered as cooling. It is useful in blood, throat, urinary system related troubles, piles, phthisis, insanity etc.

Sida cordifolia is used in the treatment of leucorrhoea, gonorrhea, general debility and rheumatism. Expressed juice of the whole plant is useful in premature ejaculation. The juice obtained from the roots is applied to unhealthy sores. Decoction of the root bark is given in sciatica and rheumatism.

S. cordifolia is used in Ayurvedic medicine, known as “malva branca”, is a plant used in the folk medicine for the treatment of inflammation of the oral mucosa, blenorrhea, asthmatic bronchitis and nasal congestion, stomatits, of asthma and nasal congestion and in many parts of Africa for various ailments, particularly for respiratory problems.It has been investigated as an anti-inflammatory, for treating cancer, and for encouraging liver re-growth. Due to its ephedrine content, it possesses psychostimulant properties, affecting the central nervous system and also the heart.

A 50% ethanolic extract of Sida cordifolia tested on rats showed potent antioxidant and antiinflammatory activity, activity comparable with the standard drug deprenyl.

The plant has demonstrated anti-pyretic and anti-ulcerogenic properties.

The aqueous extract of Sida cordifolia stimulates liver regeneration in rats.

Disclaimer:The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is  always advisable to consult with your own health care provider.

Resources:
http://en.wikipedia.org/wiki/Sida_cordifolia
http://commons.wikimedia.org/wiki/Category:Sida_cordifolia
http://www.hort.purdue.edu/newcrop/CropFactSheets/bala.html
http://www.ethnoleaflets.com/leaflets/bala.htm

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Categories
Ailmemts & Remedies

Campbell de Morgan spots

Alternative Names :    Cherry hemangioma, Senile angiomas

Definition:
Campbell de Morgan spots are made up of clusters of tiny capillaries at the surface of the skin, forming a small round dome (“papule“), which may be flat topped. They range in colour from bright red to purple. When they first develop, they may be only a tenth of a millimeter in diameter and almost flat, appearing as small red dots. However, they then usually grow to about one or two millimeters across, and sometimes to a centimeter or more in diameter. As they grow larger, they tend to expand in thickness, and may take on the raised and rounded shape of a dome. Multiple adjoining angiomas are said to form a polypoid angioma. Because the blood vessels comprising an angioma are so close to the skin’s surface, cherry angiomas may bleed profusely if they are injured.

.CLICK TO SEE THE PICTURE
These small red or violet spots most often appear on the chest or trunk and are nothing to worry about. They’re small, benign (non-cancerous) overgrowths of blood vessels in the skin. Medically, they’re called haemangioma or just angioma. Why they develop in the first place isn’t known. They’re usually less than 6mm in diameter and if pressed do not blanch.

They are the most common kind of angioma.They are called cherry angioma because of their colour, or senile angioma because they appear as a person gets older – usually first appearing after the age of 40 and increasing with age.
They are called Campbell de Morgan spots, after the nineteenth-century British surgeon Campbell De Morgan who first noted and described them.

Cherry angiomas occur in all races, ethnic backgrounds, and both sexes.
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Experts agree they’re best left alone since they’re harmless. However, some people do find them cosmetically unacceptable and wish to have them removed.

Symptoms:
Skin lesion or growth:
•Bright cherry-red
•Small — pinhead size to about 1/4 inch in diameter
•Smooth
Cause:
Campbell de Morgan spots  appear spontaneously in many people in middle age but can also, although less common, occur in young people. They can also occur in an aggressive eruptive manner in any age. The underlying cause for the development of cherry angiomas is not understood, much because of a lack of interest in the subject. This is probably because they rarely are caused by an internal malignancy.

The first study trying to bring light to the molecular and genetic mechanisms behind cherry/senile hemangioma was recently published.  The study found that the level of MicroRNA 424 is significantly reduced in senile hemangiomas compared to normal skin resulting in increased protein expression of MEK1 and Cyclin E1. By inhibiting mir-424 in normal endothelial cells they could observe the same increased protein expression of MEK1 and Cyclin E1 which, important for the development of senile hemangioma; induced cell proliferation of the endothelial cells. They also found that targeting MEK1 and Cyclin E1 with small interfering RNA decreased the number of endothelial cells.

Chemicals and compounds that have been seen to cause Campbell de Morgan spots are mustard gas, 2-butoxyethanol,   bromides   and cyclosporine.  A correlation has been seen between cherry hemangiomas and activity of the enzyme carbonic anhydrase   as well as a significant increase in the density of mast cells in cherry hemangiomas compared with normal skin.

A recent study   suggests that Prichard’s structures are the cardiac equivalent of cutaneous senile angioma. The study describes Prichard’s structures in the heart as “adult, fully differentiated, postmitotic-type endothelial cells with virtually no turnover.” and that these cells are senescent cells that “arrest growth and cannot be stimulated to re-enter the cell cycle by physiological mitogens; they become resistant to apoptotic cell death; and they acquire altered functions.”. The study concludes that Prichard’s structures are formed by “infolding of the endothelial lining of the endocardium of the fossa ovalis as an irritational response to altered blood flow, eddies or turbulence.”
Diagnosis:
Doctors  probably diagnose a cherry angioma based on the appearance of the growth. No further tests are usually necessary, though a skin biopsy may be used to confirm the diagnosis.

Treatment:
On  occasions that they require removal, traditionally cryosurgery or electrosurgery have been used. More recently pulsed dye laser or Intense Pulsed Light (IPL) treatment has also been used.

Future treatment based on a locally acting inhibitor of MEK1 and Cyclin E1 could possibly be an option. A natural MEK1 inhibitor is Myricetin.

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Prognosis:
In most patients, the number and size of cherry angiomas increases with advancing age. They are harmless, except in very rare cases that involve a sudden appearance of many angiomas, which can be a sign of a developing internal malignancy.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Resources:
http://www.bbc.co.uk/health/physical_health/conditions/campbellmorganspots.shtml
http://en.wikipedia.org/wiki/Cherry_hemangioma
http://www.nlm.nih.gov/medlineplus/ency/article/001441.htm
http://medsapiens.com/2009/03/07/cherry-hemangioma/

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Categories
Ailmemts & Remedies

Bursitis

Definition:
A bursa is a fluid-filled sac that usually overlays a bone or a joint and acts as a shock absorber. There are two types:

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Anatomical bursae normally occur around the body where tendons cross bones or joints. The complex knee joint has 15 bursae, for example.

•Adventitious bursae are not part of the normal body structure but develop when the soft tissue overlying a bone suffers repeated friction or trauma. An example of this type is over the pelvic bone in the buttock muscles because someone has been sitting on a hard chair for several hours a day.

Bursitis is inflammation of the fluid-filled sac (bursa) that lies between a tendon and skin, or between a tendon and bone. Certain occupations predispose people to this. The condition may be acute or chronic.
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Causes:
The most common causes of bursitis are trauma, infection, and crystal deposits.

Trauma
Trauma causes inflammatory bursitis from repetitive injury, which results in widening of the blood vessels. This allows proteins and extracellular fluid into the bursae and the bursae react against these “foreign” substances by becoming swollen.

•Chronic: The most common cause of chronic bursitis is minor trauma that may occur to the shoulder (subdeltoid) bursa from repetitive motion, for example, throwing a baseball. Another example is prepatellar bursitis (in front of the knee) from prolonged or repetitive kneeling on a hard surface to scrub a floor or lay carpet.

Acute brusits: A direct blow (let’s say you accidentally bang your knee into a table) can cause blood to leak into the bursa. This rapid collection usually causes marked pain and swelling, most often in the knee.

Infections:
Bursae close to the surface of the skin are the most likely to get infected with common organisms; this is called septic bursitis. These bursitis-causing bacteria are normally found on the skin: Staphylococcus aureus or Staphylococcus epidermis. People with diabetes or alcoholism and those undergoing steroid treatments or with certain kidney conditions, or who may have experienced trauma may be higher risks for this type of bursitis. About 85% of septic bursitis occurs in men.

Crystal deposits
People with certain diseases such as gout, rheumato:id arthritis, or scleroderma, for example, may develop bursitis from crystal deposits. Little is known about how this process happens. Uric acid is a normal byproduct of daily metabolism. People who have gout are unable to properly break down the uric acid, which crystalizes and deposits in joints-a mechanism for causing bursitis.
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Symptoms:
Bursitis causes pain and tenderness around the affected bone or tendon. The bursae sacs may swell, often making movement difficult. The most commonly affected joints are the shoulder, elbow, wrist and hand, knee, and foot.

Shoulder…...click & see

The subacromial (subdeltoid bursa) separates the major tendon (known as the supraspinatus tendon) from the overlying bone and deltoid muscle. Inflammation of this bursa is usually a result of injury to surrounding structures-most commonly the rotator cuff. This is often referred to as “impingement syndrome.” It is often difficult to tell the difference between this type of bursitis pain and a rotator cuff injury. Both cause pain in the side or front of the shoulder.

•Overhead lifting or reaching activities are uncomfortable.

•Pain is often worse at night.

•The shoulder will usually have decreased range of active motion and be tender at specific spots.

Elbow. click & see

Olecranon bursitis is the most common form of bursitis. Goose-egg-like, tender red swelling may appears just behind the elbow. This area is at the top of one of the forearm bones called the ulna and is known as the olecranon process.

•The pain may increase if the elbow is bent because tension increases over the bursa.

•This bursa is frequently exposed to direct trauma (bumping your arm) or repeated motions from bending and extending the elbow (while painting, for example).

•Infection is common in this bursa.

Knee....click & see

•Kneecap (prepatellar) bursitis: Swelling on the front of the kneecap is usually associated with either chronic trauma (from kneeling) or an acute blow to the knee. Swelling may occur as late as 7-10 days after a single blow to the area, usually from a fall.

•Anserine bursitis: The anserine bursa is fan shaped and lies among 3 of the major tendons at the knee. The name anserine (gooselike) comes from the shape of the swollen bursa. When restrained by the 3 tendons, the bursa looks like a goose’s foot.

This type of bursitis is most often seen in people with arthritis, especially overweight middle-aged women with osteoarthritis.

*The pain is typically produced when the knee is bent and is particularly troublesome at night. People often seek comfort by sleeping with a pillow between their thighs.

*The pain can radiate to the inner thigh and midcalf and usually increases on climbing stairs and at extremes of bending and extending.

*The area of tenderness is on the middle part of the knee.

*Anserine bursitis also occurs as an overuse or traumatic injury among athletes, particularly long-distance runners.
Ankle.click & see

Retrocalcaneal bursitis occurs when the bursa near the Achilles tendon in the ankle becomes inflamed. This is commonly caused by local trauma associated with wearing a poorly designed shoe (often high heels) or prolonged walking. It can also occur with Achilles tendonitis.

Bursitis in this part of the body often occurs as an overuse injury in young athletes, ice skaters, and female adolescents transitioning to higher heels. The pain is usually on the back of the heel and increases with passive extension or resisted flexion.

Buttocks....click & see

Ischiogluteal bursitis causes inflammation of the ischial bursa, which lies between the bottom of the pelvic bone and the overlying gluteus maximus muscle (one side of the buttocks). Inflammation can come from sitting for a long time on a hard surface or from bicycling.

•The pain occurs when sitting and walking.

•There will be tenderness over the pubic bone, which may be made worse by bending and extending the leg.

•The pain may radiate down the back of the thigh.

•Direct pressure over the area causes sharp pain.

•The person may hold the painful buttock elevated when sitting.

•The pain is worse when person is lying down and the hip is passively bent.

•The person may have difficulty standing on tiptoe on the affected side.

Hip click & see

The iliopsoas bursa is the largest in the body and lies in front of, and deep to, the hip joint. Bursitis here is usually associated with hip problems such as arthritis or injury (especially from running).

•The pain of iliopsoas bursitis radiates down the front and middle areas of the thigh to the knee and is increased when the hip is extended and rotated.

•Extension of the hip during walking causes pain so the person may limit the stride on the affected side and take a shorter step.

•There may be tenderness in the groin area.

•Sometimes a mass may be felt resembling a hernia. The person may also feel numbness or tingling if adjacent nerves are compressed by the inflamed bursa.

Thigh click & see

The trochanteric bursa, part of the thigh, can be associated trochanteric bursitis, which occurs most frequently in overweight, middle-aged women.

•It causes deep, aching hip pain along the side of the hip that may extend into the buttocks or to the side of the knee.

•Pain is aggravated by activity, local pressure, or stretching.

•Pain is often worse at night.
Diagnosis:
Exams and Tests:

•History: The doctor will usually take a detailed history about the onset of symptoms and will want to know what movement or activity makes you feel more or less pain. You will need to report other medical problems you may have.

•Fluid removal: The doctor may remove synovial fluid from the joint with a needle (aspiration) and send it to the lab for analysis for possible infection. Bursitis in the knee and elbow are especially prone to infection.

•X-rays: They are usually not helpful, but the doctor may get them if any other disease process is suspected such as a fracture or dislocation. MRI and CT scans are obtained only to exclude other causes.

•Blood testing: The doctor may take blood from your arm for lab testing to rule out infection or other conditions such as rheumatoid arthritis or hyperthyroidism.
Treatment:
The doctor will probably recommend home care with P-R-I-C-E-M: protection, rest, ice, compression, elevation, and medications .

At first  doctor may recommend temporary rest or immobilization of the affected joint.

Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen may relieve pain and inflammation. Formal physical therapy may be helpful as well.

If the inflammation does not respond to the initial treatment, it may be necessary to draw out fluid from the bursa and inject corticosteroids. Surgery is rarely required….

Exercises for the affected area should be started as the pain resolves. If muscle atrophy (weakness or decrease in size) has occurred. Your health care provider may suggest exercises to build strength and increase mobility.

Bursitis caused by infection is treated with antibiotics. Sometimes the infected bursa must be drained surgically.

Prognosis:
The condition may respond well to treatment, or it may develop into a chronic condition if the underlying cause cannot be corrected.

Complications:
Chronic bursitis may occur.
Too many steroid injections over a short period of time can cause injury to the surrounding tendons.

Prevention:
Avoid activities that include repetitive movements of any body parts whenever possible.

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Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Resources:
http://www.bbc.co.uk/health/physical_health/conditions/bursitis.shtml
http://healthtools.aarp.org/adamcontent/bursitis?CMP=KNC-360I-GOOGLE-HEA&HBX_PK=bursitis&utm_source=Google&utm_medium=cpc&utm_term=bursitis&utm_campaign=G_Diseases%2Band%2BConditions&360cid=SI_148893841_6495451981_1
http://www.emedicinehealth.com/bursitis/article_em.htm
http://www.medicalook.com/Joint_pain/Bursitis.html
http://activemotionphysio.ca/article.php?aid=246
http://www.bursitisinshoulder.com/
http://www.bursitis.ws/Knee-Bursitis.html

http://www.aidmybursa.com/foot-ankle-bursitis.php

http://www.sportlink.co.uk/hip_bursitis.php

http://www.bursitistreatment.info/ischial-bursitis_8.html

http://www.steadyhealth.com/articles/Hip_Bursitis___Trochanteric_Bursitis_a246.html

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News on Health & Science

Exercise Radically Improves Brain Power

Exercise can keep your brain sharp as you age. A new study has shown that a program of exercise can, over the course of a year, increase the size of your hippocampus, a part of the brain key to memory and spatial navigation.

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The hippocampus often shrinks in late adulthood, leading to memory impairment.

According to the Los Angeles Times:
“To complete the study, the team recruited 120 older people who didn’t exercise regularly. Half were randomly assigned to an aerobic exercise program … The group doing aerobic exercise had increases in hippocampus volume: up 2.12 percent in the left hippocampus, and 1.97 percent in the right hippocampus.”

Regular exercise can also improve the ability of overweight children to think, plan and even do math, according to other recent research. MRIs have shown that previously inactive children who start to exercise experience increased brain activity in the prefrontal cortex, an area associated with complex thinking, decision making and correct social behavior.

The more they exercise, the better the result.

Eurekalert reports:
“Intelligence scores increased an average 3.8 points in those exercising 40 minutes per day after school for three months with a smaller benefit in those exercising 20 minutes daily.  Activity in the part of their brain responsible for so-called executive function also increased in children who exercised … Similar improvements were seen in math skills”.

Resources:
*Los Angeles Times January 31, 2011

*Wall Street Journal February 22, 2011

*Proceedings of the National Academy of Sciences

*Eurekalert February 18, 2011

*Georgia Health Science News

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Categories
Herbs & Plants

Florida Fishpoison Tree(Piscidia piscipula)

Botanical Name :Piscidia piscipula
Family: Fabaceae
Genus: Piscidia
Species: P. piscipula
Kingdom: Plantae
Order: Fabales

Common Names:Florida fishpoison tree, Jamaican dogwood or Fishfuddle

Habitat : The Florida fishpoison tree grows in coastal zones. It prefers well-drained sandy soils, with a top layer of humus. The tree has some tolerance to short-term storm surges of brackish water or seawater. Although it grows in coastal conditions, the tree is usually protected from direct salt spray by adjoining vegetation. Established trees are highly tolerant of drought. Its sensitivity to the cold limits Florida fishpoison tree to areas no colder than plant hardiness zone11.

Description:
Florida fishpoison tree,  is a medium-sized, deciduous, tropical tree endemic to southern Florida, the Florida Keys, Texas, Caribbean, and Latin America.Native Americans of the West Indies discovered extracts from the tree could sedate fish, allowing them to be caught by hand. This practice led to the tree’s common names—fishpoison and fishfuddle. The tree has medicinal value as an analgesic and sedative.

The generic name is Latin for “fish killer”, and the specific name is Latin for “little fish,

 

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Size: The Florida fishpoison tree attains medium size with heights of 12 to 15 m and bole diameters of 46 to 118 cm. An irregular, open crown develops with stout, erect branches.

Foliage: Its deciduous leaves (9 to 23 cm long) are alternate and pinnately compound. Five to 11 leaflets (each 4 to 8 cm long) are present in an opposite arrangement. Leaflets are dark green above and distinctly paler grayish-green below with pubescence.

Flowers/Fruit: The white flowers are tinged with red or pink. They appear in pea-like clusters in May and are attractive to bees. Trees will potentially bloom when about 4 m tall and 4 years old. Flowers develop into a light brown, bean-like pod (8 to 10 cm long) with four papery wings. Ripening in July and August, the pods contain red-brown seeds with oval shapes.

Bark: Stem bark is thin and olive gray in color with irregular dark patches and many smaller scales. The bark has an unpleasant odor and a distinctly acrid and bitter taste, causing a burning sensation in the mouth.

Propagation: After removal from the ripe pod, seeds will germinate in 8 to 10 days when sown about 6 mm deep in moist soil. Until seedlings become well established, they should be fertilized and watered. Cuttings placed in moist soil quickly sprout roots. In fact, rooting has been observed to occur so readily that posts made from fresh timber occasionally take root unintentionally.

Medicinal Uses:
Florida fishpoison tree has long been used in traditional medicine for treating nervous conditions and pain. Recent scientific studies in animals suggest that bark extracts have potential for their anti-inflammatory, sedative, and anti-spasmodic effects.

Other Uses:e
Ornamental: In areas with a suitable climate and soils, Florida fishpoison tre makes a hardy, medium-sized shade tree with attractive seasonal flowers. It is ideal for yards and along fence rows. The species is shade intolerant, requiring full sunlight for maximum development.

Wood: The yellow-brown wood of fishpoison tree is resistant to decay, making its timber suitable for outdoor usage, such as boat building, fence posts, and poles. The dense, tight-grained wood is also used as a fuel, to make charcoal, and as a good carving material.

Fish poison: Indigenous peoples all over the world used local poisonous plants to aid in catching fish, and because of this many plants bear common names descriptive of this use. Within its natural range, Native Americans used an extract from the bark, roots, twigs, and leaves of Florida fishpoison tree to sedate fish, making them easier to catch. A number of chemicals are present in the tree’s tissues that are toxic to fish, the principal one being the well-known Rotenone.

Disclaimer:The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is  always advisable to consult with your own health care provider.

Resources

http://en.wikipedia.org/wiki/Piscidia_piscipula

Piscidia piscipula

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