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Botanical Name:Eleutherococcus senticosus (formerly Acanthopanax senticosus)
Family :Araliaceae
Kingdom: Plantae
Division: Magnoliophyta
Class: Magnoliopsida
Order: Apiales
Genus: Eleutherococcus
Species: E. senticosus

Habitat:It is native to Northeastern Asia. Eleuthero is a shrub that grows in Siberia, China, Korea, and Japan.In Chinese medicine it is known as cì wu jia
Common names: Siberian ginseng, Ci wu jia, Touch-me-not, Devil’s shrub,devil’s shrub, devil’s root, touch-me-not

Description :The herb grows in mixed and coniferous mountain forests, forming low undergrowth or is found in groups in thickets and edges. E. senticosus is sometimes found in oak groves at the foot of cliffs, very rarely in high forest riparian woodland. Its native habitat is East Asia, China, Japan and Russia. E. senticosus is broadly tolerant of soils, growing in sandy, loamy and heavy clay soils with acid, neutral or alkaline chemistry and including soils of low nutritional value. It can tolerate sun or dappled shade and some degree of pollution. E. senticosus is a decidious shrub growing to 2m at a slow rate. It is hardy to zone 3. It flowers in July in most habitats. The flowers are hermaphrodite and are pollinated by insect.

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The dried root and other underground parts of the plant are used in herbal remedies for a variety of conditions. It is a distant relative of true (Panax) ginseng (which includes Asian ginseng and American ginseng), but it does not belong to the Panax group of herbs. Previously sold in the United States as “Siberian ginseng,” a 2002 United States law forbade the “ginseng” label, and the name “eleuthero” is now more commonly used.

Active Constituents:The constituents in eleuthero that have been most studied are the eleutherosides.1 Seven primary eleutherosides have been identified, with most of the research attention focusing on eleutherosides B and E.2 Eleuthero also contains complex polysaccharides (complex sugar molecules).3 These constituents may play a critical role in eleuthero’s ability to support immune function.

Eleuthero is an “adaptogen” (an agent that helps the body adapt to stress). It is thought to help support adrenal gland function when the body is challenged by stress

Medicinal Uses:
E. senticosus is an adaptogen which has a wide range of health benefits attributed to its use. Currently, most of the research to support the medicinal use of E. senticosus is in Russian or Korean. E. senticosus contains eleutherosides, triterpenoid saponins which are lipophilic and which can fit into hormone receptors. Supporters of E. senticosus as medicine claim it possesses a variety of medicinal properties, such as:

*increased endurance

*memory improvement

*anti-inflammatory

*immunogenic

*chemoprotective

*radiological protection

Eleutherococcus senticosis is more tonifying than the true Ginsengs (Panax sp.) It is neutral energetically and so is appropriate for daily use. Taken regularly, it enhances immune function, decreases cortisol levels and inflammatory response, and it promotes improved cognitive and physical performance. In human studies Eleuthero has been successfully used to treat bone marrow suppression caused by chemotherapy or radiation, angina, hypercholesterolemia, and neurasthenia with headache, insomnia, and poor appetite.

The major constituents of E. senticosus are Ciwujianoside A-E, Eleutheroside B (Syringin), Eleutherosides A-M, Friedelin and Isofraxidin.[2][unreliable source?] Most of the active constituents in E. senticosus are triterpenoid saponins. Though all terpenoid compounds have bioactivity in mammals, it is the triterpenes that are most important to the adaptogenic effect. The majority of known triterpenoid compounds in E. senticosus are found as saponin glycosides which refers to the attachment of various sugar molecules to the triterpene unit. These sugars are usually cleaved off in the gut by bacteria, allowing the aglycone (triterpene) to be absorbed. Saponin glycosides have the characteristic of reducing surface tension of water and will strip the lipids. This allows them insert into cell membranes (Attele et al., 1999) and modify the composition, influence membrane fluidity,[8] and potentially affect signaling by many ligands and cofactors.

Eleutherococcus senticosus has been shown to have significant antidepressant effects in rats

Although not as popular as Asian ginseng, eleuthero use dates back 2,000 years, according to Chinese medicine records. Referred to as ci wu jia in Chinese medicine, it was used to prevent respiratory tract infections, colds and flu. It was also believed to provide energy and vitality. In Russia, eleuthero was originally used by people in the Siberian Taiga region to increase performance and quality of life and to decrease infections.

In more modern times, eleuthero has been used to increase stamina and endurance in Soviet Olympic athletes. Russian explorers, divers, sailors, and miners also used eleuthero to prevent stress-related illness. After the Chernobyl accident, many Russian and Ukrainian citizens were given eleuthero to counteract the effects of radiation.

Eleuthero has been shown to enhance mental acuity and physical endurance without the letdown that comes with caffeinated products. Research has shown that eleuthero improves the use of oxygen by the exercising muscle.6 This means that a person is able to maintain aerobic exercise longer and recover from workouts more quickly. Preliminary research from Russia indicates it may be effective for this purpose. Other trials have been inconclusive8 or have shown no beneficial effect.

Eleuthero may also support the body by helping the liver detoxify harmful toxins. It has shown a protective action in animal studies against chemicals such as ethanol, sodium barbital, tetanus toxoid, and chemotherapeutic agents. According to a test tube study eleuthero also helps protect the body during radiation exposure. Preliminary research in Russia has suggested that eleuthero may help alleviate side effects and help the bone marrow recover more quickly in people undergoing chemotherapy and radiation therapy for cancer.

Eleuthero may be useful as a preventive measure during the cold and flu season. However, it has not yet been specifically studied for this purpose. Preliminary evidence also suggests that eleuthero may prove valuable in the long-term management of various diseases of the immune system, including HIV infection and chronic fatigue syndrome. Healthy people taking teaspoons (10 ml) of tincture three times daily have been shown to have increased numbers of the immune cells (T4 lymphocytes) that have been found to decrease during HIV-infection and AIDS.13 Further human clinical trials are needed to confirm that eleuthero may be helpful for this disease.

Dosages: Dried, powdered root and rhizomes, 2–3 grams per day, are commonly used.14 Alternatively, 300–400 mg per day of concentrated solid extract standardized on eleutherosides B and E can be used, as can alcohol-based extracts, 8–10 ml in two to three divided dosages. Historically, eleuthero is taken continuously for six to eight weeks, followed by a one- to two-week break before resuming.

Side Effects:Reported side effects have been minimal with use of eleuthero.15 Mild, transient diarrhea has been reported in a very small number of users. Eleuthero may cause insomnia in some people if taken too close to bedtime. Eleuthero is not recommended for people with uncontrolled high blood pressure. There are no known reasons to avoid eleuthero during pregnancy and breast-feeding. However, pregnant or breast-feeding women should be aware that some products may be adulterated with herbs that should not be taken in pregnancy, such as Asian ginseng. Only eleuthero from a trusted source should be used.

In one case report, a person taking eleuthero with digoxin developed dangerously high serum digoxin levels.16 Although a clear relationship could not be established, it is wise for someone taking digoxin to seek the advise of a doctor before taking eleuthero.

Drug interactions:
Certain medicines may interact with eleuthero. Refer to drug interactions for a list of those medicines.

*People with medicated high blood pressure should consult their doctor before taking E. senticosus as it may reduce their need for medication.

*E. senticosus may cause light sleep in some people, principally those who are “wired”. Users are recommended not to take it in the evening.

*E. senticosus will enhance the effectiveness of mycin class antibiotics.

*E. senticosus when purchased from non-GMP sources has occasionally been adulterated with Periploca graeca which can potentiate digoxin or similar drugs: however this is not an interaction of E. senticosus

You may click to learn more about Eleuthero->………………………….(1)….(2).….(3)

Disclaimer:The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider

Resources:
http://en.wikipedia.org/wiki/Eleutherococcus_senticosus
http://www.revolutionhealth.com/articles/eleuthero/hn-herb_eleuthero
http://www.cancer.org/docroot/ETO/content/ETO_5_3x_Siberian_Ginseng.asp

Feeling Depleted
There are times in our lives when it seems our bodies are running on empty. We are not sick, nor are we necessarily pushing ourselves to the limit-rather, the energy we typical enjoy has mysteriously dissipated, leaving only fatigue. Many people grow accustomed to feeling this way because they do not know that it is possible to exist in any other state. The body’s natural state, however, is one of energy, clarity, and balance. Cultivating these virtues in our own bodies so that we can combat feelings of depletion is a matter of developing a refined awareness of the self and then making changes based on our observations.

A few scant moments of focused self-examination in which you assess your recent schedule, diet, and general health may help you zero in on the factors causing your depletion. If you are struggling to cope with an overfull agenda, prioritization can provide you with more time to sleep and otherwise refresh yourself. Switching to a diet containing plenty of nutritious foods may serve to restore your vigor, especially when augmented by supplements like B vitamins or ginseng. Consider, too, that a visit to a healer or homeopath will likely provide you with wonderful insights into your tiredness. But identifying the source of your exhaustion will occasionally be more complicated than spotting a void in your lifestyle and filling it with some form of literal nourishment. Since your earthly and ethereal forms are so intimately entwined, matters of the mind and heart can take their toll on your physical self. Intense emotions such as anger, sadness, jealousy, and regret need fuel to! manifest in your consciousness, and this fuel is more often than not corporeal energy. Conversely, a lack of mental and emotional stimulation may leave you feeling listless and lethargic.

Coping with and healing physical depletion will be easier when you accept that the underlying cause might be more complex than you at first imagined. A harried lifestyle or a diet low in vital nutrients can represent only one part of a larger issue affecting your mood, stamina, and energy levels. When you believe that you are ultimately in control of how you feel, you will be empowered to transform yourself and your day-to-day life so that lasting fatigue can no longer gain a foothold in your existence.

Source:Daily Om

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