Tag Archives: Ankylosing spondylitis

Tripterygium wilfordii

 

Botanical Name:Tripterygium wilfordii Hook F
Pharmaceutical name: Radix Tripterygium wilfordii
Family:Celastraceae
Chinese Name:Lui Kong Teng
Common Name : Three Wing Nut,Thunder God Vine,
Kingdom: Plantae
Division: Magnoliophyta
Class: Magnoliopsida
Order: Celastrales
Genus: Tripterygium
Species: T. wilfordii
Habitat:South part of China, Taiwan, Burma

Description:
Deciduous scandent shrub. Twigs brown, angular, downy. Leaves ovate to elliptic, 5-15 cm long, 2,5-7 cm wide, light green glabrous above, paller, very glaucous and pubescent on nerves beneath. Margin crenate, apex pointed. Small whitish flowers with 5 petals about 9 mm across, in terminal panicles in July.

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Fruit 3-winged, about 1,5 cm long, brown-red.
Click to see:more different Images for Tripterygium Wilfordii

 

Click to see:->Tripterygium wilfordii hook F extracts and components, and uses thereof


Properities
: Bitter & very toxic.

Medicinal uses: Anti inflammatory, killing worms, resolving toxins,treating proteinuric disease, using as  immuno-suppressive agent on auto immune diseases.
Tripterygium wilfordii Hook F or The Thunder God Vine, is a vine used in traditional Chinese medicine for treatment of fever, chills, edema and carbuncle. Tripterygium wilfordii recently has been investigated as a treatment for a variety of disorders including rheumatoid arthritis, chronic hepatitis, chronic nephritis, ankylosing spondylitis, as well as several skin disorders. It is also under investigation for its apparent antifertility effects, which it is speculated, may provide a basis for a Male oral contraceptive. Certain extracts from Tripterygium wilfordii, as well as from Trypterigium hypoglaucum and Tripterygium regeli, were discovered in the 1980s to have temporary antifertility effects, which has led to research on its potential as a contraceptive. Not enough is known about ..

Scientific research on medical effects:-
Certain extracts from Tripterygium wilfordii, as well as from Trypterigium hypoglaucum and Tripterygium regeli, were discovered in the 1980s to have temporary antifertility effects, which has led to research on its potential as a contraceptive.

Not enough is known about T. wilfordii to actually test it as a contraceptive. Research thus far has dealt with establishing the mechanism by which the plant affects fertility, and investigating toxicity and side effects. What has been learned is encouraging, however: in both animals and humans, low doses of various Tripterygium extracts can produce significantly lowered sperm density and motility indices without major side effects. When the treatment was ended in the various trials, all indices returned to normal within months.

The plant contains many active compounds, at least six of which have male anti-fertility effect (triptolide, tripdiolide, triptolidenol, tripchlorolide, 16-hydroxytriplide and a compound known as T7/19, whose structure is unpublished). The mechanism by which they affect fertility is not yet understood. What is known is that daily doses of these compounds reduce sperm counts and also severely affect the formation and maturation of sperm, causing them to be immotile.

At medicinal doses, T. wilfordii extract does have significant side effects, including immuno-suppression. However, this may not apply to contraceptive use. Many of the side effects are caused by the other active compounds found in the plant, and do not appear when a pure extraction of the anti-fertility agents is used. In addition, the dose required to lower fertility is significantly lower than the standard medicinal dose.

T. wilfordii could be an effective pharmaceutical alternative to contraceptives based on hormonal manipulation. Further research may shed light on its functional mechanisms, and determine whether it could be used at low enough doses to avoid unpleasant side effects.

More recently, a small molecule Triptolide derived from T. wilfordii has been shown to disrupt mitochondrial function in cells and is under investigation as an anti-tumor agent or to suppress auto-immune disorders.

The August 18th 2009 Edition of the Annals of Internal Medicine published an article showing Tripterygium wilfordii was more effective than sulphasalazine in treating rheumatoid arthritis.

Click to see:->
>The Analyst report on health benefits  & side effects of  Tripterygium wilfordii Hook F
>RightHealth Results for Tripterygium Wilfordii
>Herb extract appears to trigger ‘suicide’ in cancer cells :
>The Chinese Herbal Remedy Tripterygium wilfordii Hook F in the Treatment of Rheumatoid Arthritis

Disclaimer:The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider

Resources;
http://www.biologie.uni-ulm.de/systax/dendrologie/Triptwilflv.htm
http://alternativehealing.org/tripterygium%20wilfordii%20hook.%20f._float.htm
http://www.righthealth.com/topic/Tripterygium_Wilfordii

http://alternativehealing.org/lei_gong_teng.htm

http://en.wikipedia.org/wiki/Tripterygium_wilfordii

 

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Ankylosing Spondylitis

In ankylosing spondylitis, chronic joint inflammation particularly affects the sacroiliac joints at the back of the pelvis and the vertebrae. If the spine is severely diseased, new bone starts to grow between the vertebrae, which eventually fuse together.

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What are the causes?
The cause of ankylosing spondylitis is unknown, but about 9 in 10 people with the condition have a particular antigen called hla-b27 on the surface of most cells. This antigen is inherited, which helps explain why ankylosing spondylitis runs in families. Most people with hla-b27 do not develop the condition, and a bacterial infection is thought to trigger ankylosing spondylitis in those who are predisposed.

What are the symptoms?
The symptoms of ankylosing spondylitis usually appear in late adolescence or early adulthood and develop gradually over a period of months or even years. Men are usually more severely affected. the main symptoms include:

· Lower back pain, which may spread down into the buttocks and thighs.
· Lower back stiffness that may be worse in the morning and improves with exercise.
· Pain in other joints, such as the hips, knees, and shoulders.
· Pain and tenderness in the heels.
· Fatigue, weight loss, and mild fever.

If left untreated, ankylosing spondylitis can distort the spine, resulting in a stooped posture. if the joints between the spine and the ribs are affected, expansion of the chest becomes restricted. in some people, ankylosing spondylitis causes inflammation or damage to the tissues in the areas other than the joints, such as the eyes.

How is it diagnosed?
Your doctor may suspect that you have ankylosing spondylitis from your symptoms. he or she will perform a physical examination and may arrange for an x-ray to look for evidence of fusion in the joints of the pelvis and the spine. Your doctor may also arrange for you to have blood tests to measure the level of inflammation and look for the hla-b27 antigen.

What is the treatment?
Treatment of ankylosing spondylitis is aimed at relieving symptoms and preventing spinal deformity. Your doctor may prescribe a nonsteroidal anti-inflammatory drug to control pain and inflammation. he or she may also refer you for physical therapy, which may include breathing exercises and daily exercises to help improve posture, strengthen muscles, and prevent deformities of the spine. You may also benefit from regular, gentle physical activity, such as swimming which may help relieve pain and stiffness. If a joint such as a hip is affected, you may eventually need to have it replaced surgically. If your mobility becomes severely reduced, you may need occupational therapy and that therapist may suggest that you use specially designed equipment and furniture to help make your life easier.

What is the prognosis?
Although the condition is not curable, most people with ankylosing spondylitis are only mildly affected, causing minimum disruption of their everyday lives. Even in those people with more severe symptoms, the condition tends to become less severe with age.In many cases, early treatment and regular exercise help relieve pain and stiffness of the back and prevent deformity of the spine. However, about 1 in 20 people with ankylosing spondylitis eventually becomes disabled and has difficulty in carrying out many routine activities.

Ayurvedic Recommended Product: Rymanyl
Ayurvedic Recommended Therapy: Virechan , Basti

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Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.

Source:

http://www.charak.com/DiseasePage.asp?thx=1&id=179

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