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Plumbago zeylanica

Botanical Name : Plumbago zeylanica
Family: Plumbaginaceae
Genus: Plumbago
Species: P. zeylanica
Kingdom: Plantae
Order: Caryophyllales

Synonymous.:   Plumbago zeylanica is a species of plumbago with a pantropical distribution. Carl Linnaeus described the paleotropical P. zeylanica and neotropical P. scandens as separate species, but they are currently considered synonymous.

Common Names: Ceylon leadwort, Doctorbush or Wild leadwort
Vernacular Name:
Hindi……..Cheeta, Telugu……Chitramulamu, English……..Leadwort, Bengali…….Chita, Marathi……Chitramul, Gujrati……Chitro, Tamil……Chittiri,Chittira, Arabian…..Sheetaraj, Farsi…..Sheetar

Sanskrit Synonyms: Anala, Dahana, Pithi, Vahnisajnaka, Agni, Agnika, Jyothi, Nirdahana, Vahni, Sikhi, Vyala, Hutasana……..all these synonyms names suggest towards fire. As because it helps the digestion strength. While collecting the herb, usually the palms get burning sensation due to hotness of this herb.

Habitat : Plumbago zeylanica is native to India. Now it is cultivated in several places in the world.

Description:
Plumbago zeylanica is a herbaceous plant with glabrous stems that are climbing, prostrate, or erect. The leaves are petiolate or sessile and have ovate, lance-elliptic, or spatulate to oblanceolate blades that measure 5-9 × 2.5–4 cm in length. Bases are attenuate while apexes are acute, acuminate, or obtuse. Inflorescences are 3–15 cm in length and have glandular, viscid rachises. Bracts are lanceolate and 3-7 × 1–2 mm long. The heterostylous flowers have white corollas 17–33 mm in diameter and tubes 12.5–28 mm in length. Capsules are 7.5–8 mm long and contain are reddish brown to dark brown seeds……...CLICK & SEE THE PICTURES 

Cultivation:  Plumbago requires full sunlight to partial shade with warm temperatures. This plant thrives in well drained with slightly acidic soil. The plants require frequent fertilizers and after flowering the plants should be cut back to let them grow vigorously. It is cultivated extensively in throughout the India.
Main Chemical Constituents: Chitranone, Plumbagin, 3-Chloroplumbagin, droserone, Elliptinone, Zeylanone and Zeylinone, Maritone,
Plumbagicacid, Dihydrosterone, B-Sitosterol etc. etc.

Medicinal Uses:
Ceylon leadwort root is acrid and stimulates sweating. In Nigeria, the leaves are used in soup as a remedy against intestinal worms and fever. In Ghana the root is administered as an enema to treat piles. In the Ivory coast and Upper Volta, the root is used to treat leprosy. In Nepal, a decoction of the root is used to treat baldness. In Indian herbal medicine, the leaves and root are used to treat infections and digestive problems such as dysentery. The root is used as a vesicant, appetizer, used in skin diseases, diarrhea, dyspepsia, piles and anasarca. A paste of the root made in vinegar, milk or salt and water is an external application in leprosy and other skin ailments. It is also used in influenza and black-water fever. The root bark used as a tincture is a sudorific and antiperiodic. The milky juice of the plant is used in scabies and ulcers. The plumbago root is an emmenagogue and is used to procure abortion by a piece of the root being introduced to Cervex Uteri. Externally, a paste of the leaves and root is applied to painful rheumatic areas or to chronic and itchy skin problems. The paste acts as a counterirritant. By raising blisters and increasing circulation, it speeds the clearing of toxins from the affected area. It is stimulant and strengthens the stomach and aids its action. It increases digestive powders and stimulate appetite

Other Uses:
Plant extracts have shown potent mosquito larvicidal activity against the larvae of Aedes aegypti while showing no toxicity to fish.

Hexane extracts of Plumbago zeylanica have shown activity against canine distemper virus.

Hexane extract of plumbago zeylanicaPlumbagin shows Antimicrobial activity.

Methanol extract of plumbago zeylanicaPositive inotropic activity.

Enzymatic spectrum of herbal Plants Plumbago Linn.

Bioactive spectra of Plumbagin.

methanol extract of plumbago zeylanica shows effect on root- knot nematode Meloidogyne spp

Disclaimer : The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplement, it is always advisable to consult with your own health care provider.

Resources:
https://en.wikipedia.org/wiki/Plumbago_zeylanica

Chitrak – Plumbago zeylanica – Benefits, Usage, Dose, Side Effects


http://www.herbnet.com/Herb%20Uses_C.htm

http://www.spicesmedicinalherbs.com/plumbago-zeylanica.html

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Effective Treatment for Neuroblastoma

Experts have claimed that they have discovered an effective treatment for deadly cancer — neuroblastoma — by applying new science with a 40-year-old known drug.

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Michelle Haber, a molecular and cellular biologist in Australia, said laboratory trials with mice genetically programmed to develop neuroblastoma — a solid tumour that spreads rapidly through the body — showed the drug, DFMO, delayed the development of tumours or prevented them forming in the first place.

By combining DFMO with conventional anti-cancer drugs such as cisplatin, that was then used to treat mice with neuroblastoma, the tumours were reduced, took longer to return and some tumours never came back, according to a report published in The Australian.

Haber, executive director of Sydney-based Children’s Cancer Institute Australia for Medical Research, said, “The mice were cured. That’s something you virtually never see in aggressive neuroblastoma.”

Luciano Dalla-Pozza, head of oncology at Children’s Hospital in Sydney welcomed the series of genetic and animal experiments Haber’s team had conducted.

“If the trial was opened now, I’d unhesitantly look at enrolling patients in it,” Dalla-Pozza said.

While roughly 75 per cent of children diagnosed with other cancers survive, only 50 per cent of those diagnosed with neuroblastoma survive. Two-thirds of youngsters get an aggressive form of neuroblastoma that kills more than 80 per cent of them within a year.

Haber said discussions were under way with Sydney Children’s Hospital and the Children’s Hospital of Philadelphia for trials of combination therapy with children who had relapsed from neuroblastoma.
“For me that’s incredibly exciting,” Haber said.

Sources: The Times Of India

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