Tag: Skin

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Ailmemts & Remedies

Pimples

Other Names: Acne,Acne vulgaris, Zit or Spot

Definition;
Pimple is a kind of comedo and one of the many results of excess oil getting trapped in the pores. Some of the varieties are pustules or papules.It is an inflammatory skin condition that causes spots.Spots result from the build up of dead skin cells and grease that block the pores or hair follicles, typically on the face, upper arms, upper back and chest.

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It is not contagious and is nothing to do with not being clean.Hormonal changes, such as those related to puberty, menstruation and pregnancy, can contribute to acne.
Some medicines will also make it worse, including some contraceptive pills and steroids.

Pimples can be treated by various acne medications prescribed by a physician, or purchased at a pharmacy with a wide variety of treatments.

Acne occurs most commonly during adolescence, affecting an estimated 80–90% of teenagers in the Western world. Lower rates are reported in some rural societies.

It is 8th most common disease in the world. People may also be affected before and after puberty. Though it becomes less common in adulthood than in adolescence, nearly half of people in their twenties and thirties continue to have acne. About 4% continue to have difficulties into their forties.

Clasification:
Acne is commonly classified by severity as mild, moderate, or severe. This type of categorization can be an important factor in determining the appropriate treatment regimen. Mild acne is classically defined as open (blackheads) and closed comedones (whiteheads) limited to the face with occasional inflammatory lesions. Acne may be considered to be of moderate severity when a higher number of inflammatory papules and pustules occur on the face compared to mild cases of acne and acne lesions also occur on the trunk of the body. Lastly, severe acne is said to occur when nodules and cysts are the characteristic facial lesions and involvement of the trunk is extensive
Symptoms:
As the pores of the skin become blocked, blackheads develop and small, tender, red spots appear. These can turn into pimples or whiteheads filled with pus.Typical features of acne include seborrhea (increased oil secretion), microcomedones, comedones, papules, pustules, nodules (large papules), and possibly scarring. The appearance of acne varies with skin color. It may result in psychological and social problems.

Some of the large nodules were previously called cysts and the term nodulocystic has been used to describe severe cases of inflammatory acne.

Scars:
Acne scars are the result of inflammation within the dermal layer of skin brought on by acne and are estimated to affect 95% of people with acne vulgaris. The scar is created by an abnormal form of healing following this dermal inflammation. Scarring is most likely to occur with severe nodulocystic acne, but may occur with any form of acne vulgaris. Acne scars are classified based on whether the abnormal healing response following dermal inflammation leads to excess collagen deposition or collagen loss at the site of the acne lesion.

Atrophic acne scars are the most common type of acne scar and have lost collagen from this healing response.  Atrophic scars may be further classified as ice-pick scars, boxcar scars, and rolling scars. Ice pick scars are typically described as narrow (less than 2 mm across), deep scars that extend into the dermis.[19] Rolling scars are wider than ice pick scars (4–5 mm across) and have a wave-like pattern of depth in the skin. Boxcar scars are round or ovoid indented scars with sharp borders and vary in size from 1.5–4 mm across.

Hypertrophic scars are less common and are characterized by increased collagen content after the abnormal healing response. They are described as firm and raised from the skin. Hypertrophic scars remain within the original margins of the wound whereas keloid scars can form scar tissue outside of these borders. Keloid scars from acne usually occur in men and on the trunk of the body rather than the face.

Pigmentation:
Postinflammatory hyper pigmentation (PIH) is usually the result of nodular or cystic acne (the painful ‘bumps’ lying under the skin). They often leave behind an inflamed red mark after the original acne lesion has resolved. PIH occurs more often in people with darker skin color. Pigmented scar is a common but misleading term, as it suggests the color change is permanent. Often, PIH can be avoided by avoiding aggravation of the nodule or cyst. These scars can fade with time. However, untreated scars can last for months, years, or even be permanent if deeper layers of skin are affected. Daily use of SPF 15 or higher sunscreen can minimize pigmentation associated with acne.

Causes:
Inside the pore are sebaceous glands which produce sebum. When the outer layers of skin shed (as they do continuously), the dead skin cells left behind may become ‘glued’ together by the sebum. This causes the blockage in the pore, especially when the skin becomes thicker at puberty. The sebaceous glands produce more sebum which builds up behind the blockage, and this sebum harbours various bacteria including the species Propionibacterium acnes, causing infection and inflammation.

Genetic:
The predisposition for specific individuals to acne is likely explained in part by a genetic component, which has been supported by twin studies as well as studies that have looked at rates of acne among first degree relatives. The genetics of acne susceptibility is likely polygenic, as the disease does not follow classic Mendelian inheritance pattern. There are multiple candidates for genes which are possibly related to acne, including polymorphisms in TNF-alpha, IL-1 alpha, and CYP1A1 among others.

Hormonal:
Hormonal activity, such as menstrual cycles and puberty, may contribute to the formation of acne. During puberty, an increase in sex hormones called androgens cause the follicular glands to grow larger and make more sebum. A similar increase in androgens occurs during pregnancy, also leading to increased sebum production.[25]

Several hormones have been linked to acne including the androgens testosterone, dihydrotestosterone (DHT) and dehydroepiandrosterone sulfate (DHEAS), as well as insulin-like growth factor 1 (IGF-I) and growth hormone. Use of anabolic steroids may have a similar effect.

Acne that develops between the ages of 21 and 25 is uncommon. True acne vulgaris in adult women may be due to pregnancy or polycystic ovary syndrome.

Infectious:
Propionibacterium acnes (P. acnes) is the anaerobic bacterium species that is widely suspected to contribute to the development of acne, but its exact role in this process is not entirely clear. There are specific sub-strains of P. acnes associated with normal skin and others with moderate or severe inflammatory acne. It is unclear whether these undesirable strains evolve on-site or are acquired, or possibly both depending on the person. These strains either have the capability of changing, perpetuating, or adapting to, the abnormal cycle of inflammation, oil production, and inadequate sloughing of acne pores. One particularly virulent strain has been circulating in Europe for at least 87 years. Infection with the parasitic mite Demodex is associated with the development of acne. However, it is unclear if eradication of these mites improves acne.

Lifestyle:
Cigarette smoking is known to increase the risk of developing acne. Additionally, acne severity worsens as the number of cigarettes a person smokes increases. The relationship between diet and acne is unclear as there is no high-quality evidence. However, a high glycemic load diet is associated with worsening acne. There is weak evidence of a positive association between the consumption of milk and a greater rate and severity of acne. Other associations such as chocolate and salt are not supported by the evidence. Chocolate does contain a varying amount of sugar that can lead to a high glycemic load and it can be made with or without milk. There may be a relationship between acne and insulin metabolism and one trial found a relationship between acne and obesity. Vitamin B12 may trigger acneiform eruptions, or exacerbate existing acne, when taken in doses exceeding the recommended daily intake.

Psychological:
While the connection between acne and stress has been debated, research indicates that increased acne severity is associated with high stress levels.

Acne excorie is a type of acne in which a person picks and scratches pimples due to stress.

Diagnosis:
There are multiple scales for grading the severity of acne vulgaris, three of these being:

*Leeds acne grading technique: Counts and categorizes lesions into inflammatory and non-inflammatory (ranges from 0–10.0).
*Cook’s acne grading scale: Uses photographs to grade severity from 0 to 8 (0 being the least severe and 8 being the most severe).
*Pillsbury scale: Simply classifies the severity of the acne from 1 (least severe) to 4 (most severe).

Differential diagnosis:
Similar conditions include rosacea, folliculitis, keratosis pilaris, perioral dermatitis, and angiofibromas among others. Age is one factor that may help a physician distinguish between these disorders. Skin disorders such as perioral dermatitis and keratosis pilaris can mimic acne but tend to occur more frequently in childhood whereas rosacea tends to occur more frequently in older adults. Facial redness triggered by heat or the consumption of alcohol or spicy food is suggestive of rosacea. The presence of comedones can also help health professionals differentiate acne from skin disorders that are similar in appearance

Treatment:
Many different treatments exist for acne including benzoyl peroxide, antibiotics, retinoids, antiseborrheic medications, anti-androgen medications, hormonal treatments, salicylic acid, alpha hydroxy acid, azelaic acid, nicotinamide, and keratolytic soaps. They are believed to work in at least four different ways, including the following: normalizing skin cell shedding and sebum production into the pore to prevent blockage, killing P. acnes, anti-inflammatory effects, and hormonal manipulation.

Commonly used medical treatments include topical therapies such as retinoids, antibiotics, and benzoyl peroxide and systemic therapies including oral retinoids, antibiotics, and hormonal agents. Procedures such as light therapy and laser therapy are not considered to be first-line treatments and typically have an adjunctive role due to their high cost and limited evidence of efficacy
Over-the-counter medications:
Common over-the-counter medications for pimples are benzoyl peroxide and/or salicylic acid and antibacterial agents such as triclosan. Both medications can be found in many creams and gels used to treat acne (acne vulgaris) through topical application. Both medications help skin slough off more easily, which helps to remove bacteria faster. Before applying them the patient needs to wash his or her face with warm water and dry. A cleanser may also be used for that purpose. Acne rosacea is not caused by bacterial infection. It is commonly treated with tretinoin. A regimen of keeping the affected skin area clean plus the regular application of these topical medications is usually enough to keep acne under control, if not at bay altogether. The most common product is a topical treatment of benzoyl peroxide, which has minimal risk apart from minor skin irritation that may present similar as a mild allergy. Recently nicotinamide, applied topically, has been shown to be more effective in treatment of pimples than antibiotics such as clindamycin. Nicotinamide (vitamin B3) is not an antibiotic and has no side-effects typically associated with antibiotics. It has the added advantage of reducing skin hyperpigmentation which results in pimple scars.

Prescription medication:
Severe acne usually indicates the necessity of prescription medication to treat the pimples. Prescription medications used to treat acne and pimples include isotretinoin, which is a retinoid. Historically, antibiotics such as tetracyclines and erythromycin were prescribed. While they were more effective than topical applications of benzoyl peroxide, the bacteria eventually grew resistant to the antibiotics and the treatments became less and less effective. Also, antibiotics had more side effects than topical applications, such as stomach cramps and severe discoloration of teeth. Common antibiotics prescribed by dermatologists include doxycycline and minocycline.  For more severe cases of acne dermatologists might recommend accutane, a retinoid that is the most potent of acne treatments. However, accutane can cause various side effects including vomiting, diarrhea, and birth defects (women).

Hygiene:
Practicing good hygiene, including regularly washing skin areas with neutral cleansers, can reduce the amount of dead skin cells and other external contaminants on the skin that can contribute to the development of pimples. However, it is not always possible to completely prevent pimples, even with good hygiene practices.

Alternative medicine:
Numerous natural products have been investigated for treating people with acne. Low-quality evidence suggests topical application of tea tree oil or bee venom may reduce the total number of skin lesions in those with acne. There is a lack of high-quality evidence for the use of acupuncture, medicine, and cupping therapy for acne.

Perfectly balanced hormones give a person a pimple-free face. One could try to correct internal hormonal levels by exercising aerobically (jog, swim, run, cycle) for 40 minutes a day, preferably in the fresh air. This needs to be balanced with 20 minutes of stretching and yoga with pranayama.

Prognosis:
Acne usually improves around the age of 20 but may persist into adulthood. Permanent physical scarring may occur. There is good evidence to support the idea that acne has a negative psychological impact and worsens mood, lowers self-esteem, and is associated with a higher risk of anxiety, depression, and suicidal thoughts.

Research:
In 2007, the first genome sequencing of a P. acnes bacteriophage (PA6) was reported. The authors proposed applying this research toward development of bacteriophage therapy as an acne treatment in order to overcome the problems associated with long-term antibiotic therapy, such as bacterial resistance.

A vaccine against inflammatory acne has been tested successfully in mice, but has not yet been proven to be effective in humans. Other workers have voiced concerns related to creating a vaccine designed to neutralize a stable community of normal skin bacteria that is known to protect the skin from colonization by more harmful microorganisms.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Resources:
https://en.wikipedia.org/wiki/Acne_vulgaris#Management

Acne


https://en.wikipedia.org/wiki/Pimple
http://www.telegraphindia.com/1150810/jsp/knowhow/story_36267.jsp

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Herbs & Plants

Chamomile

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Botanical Name: Matricaria chamomilla
Family: Asteraceae
Tribe: Anthemideae
Genus: Matricaria
Species: M. chamomilla
Kingdom: Plantae
Order: Asterales

Synonym: Matricaria recutita

Common Names:Chamomile, German chamomile, Hungarian chamomile (kamilla), wild chamomile or scented mayweed,

Habitat:Chamomile is native to southern and eastern Europe. It is also grown in Germany, Hungary, France, Russia, Yugoslavia, and Brazil. It was introduced to India during the Mughal period, now it is grown in Punjab, Uttar Pradesh, Maharashtra, and Jammu and Kashmir. The plants can be found in North Africa, Asia, North and South America, Australia, and New Zealand. Hungary is the main producer of the plant biomass. In Hungary, it also grows abundantly in poor soils and it is a source of income to poor inhabitants of these areas. Flowers are exported to Germany in bulk for distillation of the oil. It often grows near roads, around landfills, and in cultivated fields as a weed, because the seeds require open soil to survive.

Description:
Chamomile is an annual plant with thin spindle-shaped roots only penetrating flatly into the soil. The branched stem is erect, heavily ramified, and grows to a height of 10–80 cm. The long and narrow leaves are bi- to tripinnate. The flower heads are placed separately, they have a diameter of 10–30 mm, and they are pedunculate and heterogamous. The golden yellow tubular florets with 5 teeth are 1.5–2.5 mm long, ending always in a glandulous tube. The flowers bloom in early to midsummer, and have a strong, aromatic smell. The flowers are 6–11 mm long, 3.5 mm wide, and arranged concentrically. The receptacle is 6–8 mm wide, flat in the beginning and conical, cone-shaped later, hollow—the latter being a very important distinctive characteristic of Matricaria—and without paleae. The fruit is a yellowish brown achene.

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Cultivation:
German chamomile can be grown on any type of soil, but growing the crop on rich, heavy, and damp soils should be avoided. It can also withstand cold weather with temperature ranging from 2°C to 20°C. The crop has been grown very successfully on the poor soils (loamy sand) at the farm of the Regional Research Laboratory, Jammu. At Banthra farm of the National Botanical Research Institute, Lucknow, the crop has been grown successfully on soil with a pH of 9. Soils with pH 9–9.2 are reported to support its growth. In Hungary, it grows extensively on clayey lime soils, which are barren lands and considered to be too poor for any other crop. Temperature and light conditions (sunshine hours) have greater effect on essential oils and azulene content, than soil type. Chamomile possesses a high degree of tolerance to soil alkalinity. The plants accumulate fairly large quantity of sodium (66 mg/100 gm of dry material), which helps in reducing the salt concentration in the top soil.[43] No substantial differences were found in the characteristics of the plants grown 1500 km apart (Hungary–Finland). Under cooler conditions in Finland, the quantity of the oxide type in the essential oil was lower than in Hungary.

Propagation:
The plant is propagated by seeds. The seeds of the crop are very minute in size; a thousand seeds weigh 0.088–0.153 gm. About 0.3–0.5 kg of clean seed with a high germination percentage sown in an area of 200–250 m2 gives enough seedlings for stocking a hectare of land. The crop can be grown by two methods i.e. direct sowing of the seed and transplanting. Moisture conditions in the field for direct sowing of seeds must be very good otherwise a patchy and poor germination is obtained. As direct sowing of seeds usually results in poor germination, the transplanting method is generally followed. The mortality of the seedlings is almost negligible in transplanting.

Medicinal Uses:
Chamomile is used in herbal medicine for a sore stomach, irritable bowel syndrome, and as a gentle sleep aid. It is also used as a mild laxative and is anti-inflammatory and bactericidal. It can be taken as an herbal tea, two teaspoons of dried flower per cup of tea, which should be steeped for 10 to 15 minutes while covered to avoid evaporation of the volatile oils. The marc should be pressed because of the formation of a new active principle inside the cells, which can then be released by rupturing the cell walls, though this substance only forms very close to boiling point. For a sore stomach, some recommend taking a cup every morning without food for two to three months. It has been studied as a mouthwash against oral mucositis ]and may have acaricidal properties against certain mites, such as Psoroptes cuniculi.

One of the active ingredients of its essential oil is the terpene bisabolol. Other active ingredients include farnesene, chamazulene, flavonoids (including apigenin, quercetin, patuletin and luteolin) and coumarin.

Dried chamomile has a reputation (among herbalists) for being incorrectly prepared because it is dried at a temperature above the boiling point of the volatile components of the plant.

Chamomile is used topically in skin and mucous membrane inflammations and skin diseases. It can be inhaled for respiratory tract inflammations or irritations; used in baths as irrigation for anogenital inflammation; and used internally for GI spasms and inflammatory diseases. However, clinical trials supporting any use of chamomile are limited.

Possible Side Effects:
Chamomile, a relative of ragweed, can cause allergy symptoms and can cross-react with ragweed pollen in individuals with ragweed allergies. It also contains coumarin, so care should be taken to avoid potential drug interactions, e.g. with blood thinners.

While extremely rare, very large doses of chamomile may cause nausea and vomiting. Even more rarely, rashes may occur. A type-IV allergic reaction with severe anaphylaxis has been reported in a 38-year old man who drank chamomile tea.

Disclaimer : The information presented herein is intended for educational purposes only. Individual results may vary, and before using any
supplement, it is always advisable to consult with your own health care provider.

Resources:
http://en.wikipedia.org/wiki/Matricaria_chamomilla
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210003/
http://www.drugs.com/npp/chamomile.html

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Gotu kola (Hemidesmus indicus)

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Botanical Name : Hemidesmus indicus
Family:Apocynaceae
Subfamily:Asclepiadoideae
Genus:Hemidesmus
Species:H. indicus
Kingdom: Plantae
Order:Gentianales

Synonyms: Hydrocotyle asiatica – L.

Common Names:Gotu Kola,Centella, March Pennywort, Indian Pennywort, Hydrocotyle, Brahmi (Sanskrit), Luei Gong Gen (Chinese)(Note: Gotu kola should not be confused with kola nut.)

In South Asia, other common names of centella include:

Thalkudi in Oriya;  Sarswathi aku in Telugu;  Kudavan, (Muththil), or  Kudangal  in Malayalam;   Thankuni  in Bengali;  Gotu kola  in Sinhala;  Brahmi  in Marathi:  Ondelaga  in Kannada;   Vallaarai  in Tamil; Brahmi booti in Hindi; Perook in Manipuri;   Manimuni  in  Assamese;Timare in Tulu; Tangkuanteh in Paite;   Brahmabuti or  Ghod-tapre  in Nepali; and  Kholcha ghyan  in Newari  Nepal Bhasa.

Habitat :Centella asiatica is native to E. Asia – India, China and Japan. Australia. Grows on Old stone walls and rocky sunny places in lowland hills and especially by the coast in central and southern Japan. Shady, damp and wet places such as paddy fields, and in grass thickets

Description:
Centella asiatica is an evergreen Perennial plant growing to 0.2m by 1m.
It is hardy to zone 8 and is frost tender.

click to see the picture..

The stems are slender, creeping stolons, green to reddish-green in color, connecting plants to each other. It has long-stalked, green, reniform leaves with rounded apices which have smooth texture with palmately netted veins. It is in leaf all year, in flower from July to August, and the seeds ripen from August to September. The flowers are hermaphrodite (have both male and female organs) and are pollinated by Insects.

The flowers are pinkish to red in color, born in small, rounded bunches (umbels) near the surface of the soil. Each flower is partly enclosed in two green bracts. The hermaphrodite flowers are minute in size (less than 3 mm), with 5-6 corolla lobes per flower. Each flower bears five stamens and two styles. The fruit are densely reticulate, distinguishing it from species of Hydrocotyle which have smooth, ribbed or warty fruit. The plant is self-fertile. The leaves are borne on pericladial petioles, around 2 cm. The rootstock consists of rhizomes, growing vertically down. They are creamish in color and covered with root hairs.

Cultivation:
Prefers a moist to wet soil in sun or partial shade. Plants also grow on walls in the wild and so should tolerate drier conditions[K]. This species is not hardy in the colder areas of the country, it tolerates temperatures down to between -5 and -10°c. It grows and spreads very well outdoors during the summer in most parts of the country and is very easy to increase by division. It can therefore be grown as a summer crop with divisions being taken during the growing season and overwintered in a greenhouse in case the outdoor plants are killed by winter cold.

Propagation:
Seed – sow spring in a greenhouse. Prick out the seedlings into individual pots when they are large enough to handle and grow them on in a greenhouse for their first winter. Plant them out in late spring or early summer of the following year, after the last expected frosts[K]. Division is simple at any time in the growing season, though the spring is probably best[K]. We find that it is best to pot up the divisions until they are rooting away well, though in selected mild gardens it should be possible to plant the divisions out directly into their permanent positions

Edible Uses:
Edible Parts: Leaves.

Leaves – raw or cooked. Used in salads and in curries. Cooked as a vegetable. An aromatic flavour, we have found them to be rather overpowering in salads when used in any but small quantities.

Medicinal Uses:
Adaptogen; Antiinflammatory; Cardiac; Depurative; Diuretic; Febrifuge; Hypotensive; Nervine; Sedative; Skin; Tonic.

Gotu kola is an outstandingly important medicinal herb that is widely used in the Orient and is becoming increasingly popular in the West. Its Indian name is ‘Brahmi’ which means ‘bringing knowledge of the Supreme Reality’ and it has long been used there medicinally and as an aid to meditation. It is a useful tonic and cleansing herb for skin problems and digestive disorders. In India it is chiefly valued as a revitalizing herb that strengthens nervous function and memory. The whole plant is alterative, cardio-depressant, hypotensive, weakly sedative and tonic. It is a rejuvenating diuretic herb that clears toxins, reduces inflammations and fevers, improves healing and immunity, improves the memory and has a balancing effect on the nervous system. It has been suggested that regular use of the herb can rejuvenate the nervous system and it therefore deserves attention as a possible cure for a wide range of nervous disorders including multiple sclerosis[K]. Recent research has shown that gotu kola reduces scarring, improves circulatory problems in the lower limbs and speeds the healing process. It is used internally in the treatment of wounds, chronic skin conditions (including leprosy), venereal diseases, malaria, varicose veins, ulcers, nervous disorders and senility. Caution should be observed since excess doses cause headaches and transient unconsciousness. Externally, the herb is applied to wounds, haemorrhoids and rheumatic joints. The plant can be harvested at any time of the year and is used fresh or dried. Another report says that the dried herb quickly loses its medicinal properties and so is best used fresh.

Medicinal Uses and Indications

Treatment :

Wound Healing and Skin Lesions
Gotu kola contains triterpenoids, compounds that have been shown to aid in wound healing. For example, animal studies indicate that triterpenoids strengthen the skin, increase the concentration of antioxidants in wounds, and restore inflamed tissues by increasing blood supply. Because of these properties, gotu kola has been used externally for burns, psoriasis, prevention of scar formation following surgery, recovery from an episiotomy following vaginal delivery of a newborn, and treatment of external fistulas (a tear at or near the anus).

Venous Insufficiency and Varicose Veins
When blood vessels lose their elasticity, blood pools in the legs and fluid leaks out of the blood vessels, causing the legs to swell (venous insufficiency). In a study of 94 people with venous insufficiency, those who took gotu kola reported a significant improvement in symptoms compared to those who took placebo. In another study of people with varicose veins, ultrasound examination revealed improvements in the vascular tone of those who took gotu cola.

High Blood Pressure

In a study of people with heart disease and high blood pressure, those who took abana (an Ayurvedic herbal mixture containing gotu kola) experienced a significant reduction in diastolic blood pressure (pressure on blood vessels when the heart is at rest) compared to those who took placebo. Further studies are needed to determine whether gotu kola alone, some other herb in the Ayurvedic mixture, or the particular combination of all the herbs in the remedy is responsible for the beneficial effect.
Anxiety
Triterpenoids (active compounds in gotu kola) have been shown to soothe anxiety and boost mental function in mice. A recent study found that people who took gotu kola were less likely to be startled by a novel noise (a potential indicator of anxiety) than those who took placebo. Although the results of this study are somewhat promising, the dose used in this study was extremely high, making it difficult to draw any conclusions about how gotu kola might be used by people with anxiety.

Scleroderma
One study involving 13 females with scleroderma found that gotu kola decreased joint pain, skin hardening, and improved finger movement.

Insomnia

Because of sedative effects demonstrated in animals, gotu kola has been used to help people with insomnia.

Dosage and Administration :
Gotu kola is available in teas, as dried herbs, tinctures, capsules, tablets, and ointments. It should be stored in a cool, dry play and used before the expiration date on the label.

Pediatric :
There is currently no information in the scientific literature about the use of gotu kola for children. Therefore, it is not recommended for those under 18 years old.

Adult
The adult dosage of gotu kola may vary depending on the condition being treated. An appropriately trained and certified herbalist, such as a naturopath, can provide the necessary guidance.

The standard dose of gotu kola varies depending on the form:

Dried herb  to make tea, add ¼ to ½ tsp dried herb to a cup of boiling water (150 mL) for 10 minutes, 3 times a day
Powdered herb (available in capsules)  1,000 to 4,000 mg, 3 times a day
Tincture (1:2, 30% alcohol) 30 to 60 drops (equivalent to 1.5 to 3 mL – there are 5 mL in a teaspoon), 3 times a day
Standardized extract—60 to 120 mg per day; standardized extracts should contain 40% asiaticoside, 29% to 30% asiatic acid, 29% to 30% madecassic acid, and 1% to 2% madecassoside; doses used in studies mentioned in the treatment section range from 20 mg (for scleroderma) up to 180 mg (in one study for venous insufficiency; although, most of the studies for this latter condition were conducted using 90 mg to 120 mg per day).
The recommended dosage for people with insomnia is ½ tsp of dried herb in a cup of water taken for no more than 4 to 6 weeks.

Precautions
The use of gotu kola for more than 6 weeks is not recommended. People taking the herb for an extended period of time (up to 6 weeks) should take a 2-week break before taking the herb again.

Asiaticoside, a major component of gotu kola, has also been associated with tumor growth in mice. Though more studies are needed, it is wise for anyone with a history of precancerous or cancerous skin lesions   such as squamous cell, basal cell skin cancer, or melanoma  to refrain from taking this herb.

Side Effects
Side effects are rare but may include skin allergy and burning sensations (with external use), headache, stomach upset, nausea, dizziness, and extreme drowsiness. These side effects tend to occur with high doses of gotu kola.

Pregnancy and Breastfeeding
Pregnant women should not take gotu kola because it may cause spontaneous abortion. There is little or no information regarding the safety of this herb during breastfeeding, so nursing mothers should refrain from taking this herb.

Geriatric Use
People older than 65 years should take gotu kola at a lower than standard dose. The strength of the dosage can be increased slowly over time to reduce symptoms. This is best accomplished under the guidance of an appropriately trained and certified herbalist such as a naturopathic doctor.

Interactions and Depletions
There have been no reports documenting negative interactions between gotu kola and medications to date. Since high doses of gotu kola can cause sedation, individuals should refrain from taking this herb with medications that promote sleep or reduce anxiety.

Disclaimer:
The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

Resources:

http://en.wikipedia.org/wiki/Centella_asiatica

http://digedibles.com/database/plants.php?Centella+asiatica

www.umm.edu/altmed/ConsHerbs

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Ailmemts & Remedies

Acanthosis nigricans

Definition:
Acanthosis nigricans is a fairly common skin pigmentation disorder.It is a brown to black, poorly defined, velvety hyperpigmentation of the skin. It is usually found in body folds, such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead, and other areas.

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Types:
This is conventionally divided into benign and malignant forms., although may be divided into syndromes according to cause.

*Benign This may include obesity-related, hereditary, and endocrine forms of acanthosis nigricans.

*Malignant. This may include forms that are associated with tumour products and insulin-like activity, or tumour necrosis factor.

An alternate classification system still used to describe acanthosis nigricans was proposed in 1994 by dermatologist Schwartz. This classification system delineates acanthosis nigricans syndromes according to their associated syndromes, including benign and malignant forms, forms associated with obesity and drugs, acral acanthosis nigricans, unilateral acanthosis nigricans, and mixed and syndromic forms.

Acanthosis nigricans may be a sign of a more serious health problem such as pre-diabetes. The most effective treatments focus on finding and resolving medical condition at the root of the problem. Fortunately, these skin patches tend to disappear after successfully treating the root condition.

Signs and symptoms:
Acanthosis nigricans may present with thickened, relatively darker areas of skin on the neck, armpit and in skin folds.These patches may also appear on the groin, elbows, knees, knuckles, or skin folds. Lips, palms, and soles of the feet.

Causes:
It typically occurs in individuals younger than age 40, may be genetically inherited, and is associated with obesity or endocrinopathies, such as hypothyroidism, acromegaly, polycystic ovary disease, insulin-resistant diabetes, or Cushing’s disease.

This occurs when epidermal skin cells begin to rapidly reproduce. This abnormal skin cell growth is most commonly triggered by high levels of insulin in the blood. In rare cases, the increase in skin cells may be caused by medications, cancer, or other medical conditions, as describe below.

*Too Much Insulin
The most frequent trigger for acanthosis nigricans is too much insulin in your bloodstream. Here’s why.

When you eat, your body converts carbohydrates into sugar molecules such as glucose. Some of this glucose is used for energy while the rest is stored. In order to use the glucose for energy, insulin must also be used. The insulin enables the glucose to enter the cells.

Overweight people tend to develop resistance to insulin over time. So although the pancreas is making insulin, the body cannot use it properly. This creates a buildup of glucose in the bloodstream, which can result in high levels of both blood glucose and insulin in your bloodstream.

Excess insulin causes normal skin cells to reproduce at a rapid rate. For those with dark skin, these new cells have more melanin. This increase in melanin produces a patch of skin that is darker than the skin surrounding it. Thus, the presence of acanthosis nigricans is a strong predictor of future diabetes. If this is indeed the cause, it is relatively easy to correct with proper diet, exercise, and blood sugar control.

*Medications:
Acanthosis nigricans can also be triggered by certain medications such as birth control pills, human growth hormones, thyroid medications, and even some body-building supplements. All of these medications can cause changes in insulin levels. Medications used to ease the side effects of chemotherapy have also been linked to acanthosis nigricans. In most cases, the condition clears up when the medications are discontinued.

Some Other Causes:(Potential but rare)

#stomach cancer (gastric adenocarcinoma)
#adrenal gland disorders such as Addison’s disease
#disorders of the pituitary gland
#low levels of thyroid hormones
#high doses of niacin

Diagnosis:
Acanthosis nigricans is typically diagnosed clinically.It is easy to recognize by sight. The doctor may want to check for diabetes or insulin resistance as the root cause. These tests may include blood glucose tests or fasting insulin tests. Your doctor may also review all your medications to see if they are a contributing factor.

It is important to inform the doctor of any dietary supplements, vitamins, or muscle-building supplements you may be taking in addition to your prescription medications.

In rare cases, the doctor may perform other tests such as a small skin biopsy to rule out other possible causes.

Treatment :
People with acanthosis nigricans should be screened for diabetes and, although rare, cancer. Controlling blood glucose levels through exercise and diet often improves symptoms. Acanthosis nigricans maligna may resolve if the causative tumor is successfully removed.

Cosmetic treatments exist for cases that are especially unsightly or embarrassing. Dark patches may be covered up with cosmetics or lightened with prescription skin lighteners. Although these treatments are not as effective as treating the root cause of the condition, they can provide some relief. Available skin lighteners include Retin-A, 20 percent urea, alpha hydroxy acids, and salicylic acid.

Prognosis:
Acanthosis nigricans often fades if the underlying cause can be determined and treated  properly.

Prevention:
Maintaining a healthy lifestyle & exercisIng regularly can usually prevent Acanthosis nigricans. Losing weight, controlling your diet, and, perhaps adjusting any medications that are contributing to the condition are all crucial steps. Healthier lifestyle choices will also reduce your risks for many other types of illnesses.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Resources:
http://www.healthline.com/health/acanthosis-nigricans#Definition
http://en.wikipedia.org/wiki/Acanthosis_nigricans

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Ailmemts & Remedies Pediatric

Impetigo

Definition:–

Impetigo is a highly contagious skin infection which is most commonly seen in babies as well as small children. It causes red sores that can break open, ooze fluid, and develop a yellow-brown crust. These sores can occur anywhere on the body but most often appear around the mouth and nose.

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It can occur in adults but is seen far more often in children. Impetigo is contagious and can be spread to others through close contact or by sharing towels, sheets, clothing, toys, or other items. Scratching can also spread the sores to other parts of the body.

Symptoms:–
You or your child may have impetigo if you have sores:

*Small red spots typically appear on the skin of the face (especially around the mouth and nose), neck or hands, although any part of the body may be affected.The spots may be clustered or merge together. The centre of each one rapidly becomes a blister, which then bursts, oozing a typical golden fluid. Crusts form over the red spots, which may be itchy or slightly sore.

* The sores begin as small red spots, then change to blisters that eventually break open. The sores are generally not painful, but they may be itchy.

*That ooze fluid and look crusty. Sores often look like they have been coated with honey or brown sugar.

*That increase in size and number. Sores may be as small as a pimple or larger than a coin.

*In babies, impetigo often occurs in the nappy area.

*New crops of spots may appear over several days or weeks (if untreated) and the infection is easily spread to other parts of the body.

Causes:–
Impetigo is caused by one of two kinds of bacteria—strep (streptococcus) or staph (staphylococcus). Often these bacteria enter the body when the skin has already been irritated or injured because of other skin problems such as eczema, poison ivy, insect bites or scratches, or nappy rash (in babies), chickenpox, burns, or cuts. Children may get impetigo after they have had a cold or allergies that have made the skin under the nose raw.In these situations the bacteria can more easily penetrate the skin’s defences and establish an infection. However, impetigo can also develop in completely healthy skin.
Risk Factors
Factors that increase your chance for impetigo include:

*Age: preschool and school-aged children
*Touching a person with impetigo
*Touching the clothing, towels, sheets, or other items of a person with impetigo
*Poor hygiene, particularly unwashed hands and dirty fingernails
*Crowded settings where there is direct person-to-person contact, such as schools and the military
*Warm, humid environment
*Seasonal: Summer
*Poor health or weakened immune system
*Tendency to have skin problems such as eczema , poison ivy , or skin allergy
*Cuts, scratches, insect bites , or other injury or trauma to the skin
*Chickenpox
*Lice infections (like scabies , head lice , or public lice ), which cause scratching

Diagnosis:–
Doctors can usually diagnose impetigo just by looking at  child’s skin. Sometimes doctor gently remove a small piece of a sore to send to a lab in order to identify the bacteria. If you or your child have other signs of illness,  the doctor may order blood or urine tests

Treatment:–
Impetigo is treated with antibiotics. For cases of mild impetigo, a doctor will prescribe an antibiotic ointment or cream to put on the sores. For cases of more serious impetigo, a doctor may also prescribe antibiotic pills.

After 3 days of treatment, you or your child should begin to get better. A child can usually return to school or daycare after 48 hours of treatment. If you apply the ointment or take the pills exactly as prescribed, most sores will be completely healed in 1 week.

At home, you should gently wash the sores with soap and water before you apply the medicine. If the sores are crusty, soak them in warm water for 15 minutes, scrub the crusts with a washcloth to remove them, and pat the sores dry. Do not share washcloths, towels, pillows, sheets, or clothes with others and be sure to wash these items in hot water before you use them again.

Try not to scratch the sores because scratching can spread the infection to other parts of the body. You can help prevent scratching by keeping your child’s fingernails short and covering sores with gauze or bandages.

Call your doctor if an impetigo infection does not improve after 3 or 4 days or if you notice any signs that the infection is getting worse such as fever, increased pain, swelling, warmth, redness, or pus.

Prevention:–
f you know someone who has impetigo, try to avoid close contact with that person until his or her infection has gone away. You should also avoid sharing towels, pillows, sheets, clothes, toys, or other items with an infected person. If possible, wash any shared items in hot water before you use them again.

If you or your child has impetigo, scratching the sores can spread the infection to other areas of your body and to other people. Keeping the sores covered can help you or your child resist scratching them. Washing your or your child’s hands with soap can also prevent spreading the infection.

If your child has a cut or insect bite, covering it with antibiotic ointment or cream can help prevent impetigo.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose

Resources:
*http://www.bing.com/images/search?q=pictures+of+impetigo&id=66954188E428748C5C3FE74DC0B51F5FB5506A49&FORM=IGRE2
*http://www.everydayhealth.com/health-center/impetigo.aspx
*http://www.bbc.co.uk/health/physical_health/conditions/impetigo2.shtml

*http://www.lifescript.com/Health/A-Z/Conditions_A-Z/Conditions/I/Impetigo.aspx?gclid=CK-inOjLmKkCFcW8KgodIhWnwQ&trans=1&du=1&ef_id=S81NxKI5DCoAAIRd:20110603013319:s

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