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Herbs & Plants Herbs & Plants (Spices)

Paprika

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History/Region of Origin:
Paprika, as a member of the capsicum family, is indigenous to the Western Hemisphere. The pepper is grown widely and takes on a slightly different flavor depending on local soil and climatic conditions.

Geographical Sources:
The peppers used in Paprika are grown in Hungary, Spain, South America, and California.
General Description:
Paprika is a spice made from the grinding of dried sweet red bell peppers (Capsicum annuum). In many European countries the name paprika also refers to bell peppers generally. The seasoning is used in many cuisines to add colour and flavour to dishes.

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According to the Oxford English Dictionary, the word comes from the Hungarian “paprika”, which derives from the Serbian “paprika”, which is a diminutive of “papar”, which in turn was derived from the Latin “piper”, for “pepper.”

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Paprika is used as an ingredient in a broad variety of dishes throughout the world. Paprika (pimentón in Spain, colorau in Portugal, chiltoma in Nicaragua, but these “paprikas” are not made exclusively from bell peppers, other varieties are used, and there are several hot and sweet “paprikas”) is principally used to season and colour rices, stews, and soups, such as goulash. In Spain, Germany, Hungary, Slovakia, Bosnia and Herzegovina, Croatia, Serbia, Turkey and Portugal, paprika is also used in the preparation of sausages as an ingredient that is mixed with meats and other spices. Paprika may be smoked for additional flavour.

Paprika is a spice which comes from a mild red pepper in the family Capsicum annum. It is a brilliant red powder and often used as a garnish.

In India, a similar powdered spice comes from a fruit locally called ‘deghi mirchi’, which is grown widely and takes on a slightly different flavour depending on local soil and climatic conditions. The hottest paprikas are not the bright red ones, but rather the palest red and light brown coloured ones.
Sorts of Hungarian paprika (in brackets the Hungarian name):

Traditional Ethnic Uses:
Paprika is the main flavor in Hungarian cooking, including dishes such as Goulash and Chicken Paprikash. In the United States, it is often used as a garnish on stuffed eggs, fish, and cheese and vegetable casseroles. Spanish Paprika flavors shellfish, rice, and sausage dishes. In Morocco, Paprika is used in tomato dishes and salads.
Taste and Aroma:
Paprika ranges from sweet and mild to hot. American Paprika is the blandest, while Hungarian Paprika has the greatest range of flavor.

Paprika is useful as a simple garnish for almost any savory dish. Combine it with butter, margarine, or oil for a quick baste for fish or poultry. This is especially good on roast turkey. Paprika can be mixed with bread crumbs before sprinkling them over casseroles or vegetables.

Click to learn about Medicinal Properties of Chile Peppers

Click to learn medicinal uses and side effects

Resources:
http://en.wikipedia.org/wiki/Paprika
http://www.culinarycafe.com/Spices_Herbs/Paprika.html

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Herbs & Plants

Nageshar or Nagchampa (Messua Ferra)

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Botanical Name:Mesua Ferrea
Family : Guttiferae
Indian Name :Mesua nagesarium /Nag champa or Nageshar

Vernacular Name:: Sans: Nagakeshara; Eng : Iron-wood.Hind : Naageswar;
Parts Used :Bark, Leaf, Flower

Description:.

Mesua nagesarium is a moderate to large sized evergreen tree with 40-60 feet height. Leaves red when young, lanceolate, covered with waxy bloom underneath. Flowers white and fragrant. Found all over the country.

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Medicinal uses: Flowers, seeds and leaves are used as medicine. Flowers are used as astringent, coughs and bowel complaints. Bark extracts also used to cure astringent. Seeds oil is used as eczema and rheumatism.
Useful in the treatment of Asthma, Skin, Burning, Vomiting, Dysentry and Piles.
Various parts of these plants mainly including flowers, fruits are commonly used in the treatment of rheumatism, skin diseases, dysentery and bleeding piles. For bleeding piles, powder of Nagkeshar (Messua ferra) and Lodhra (Symplocos recemosa) should be taken in the dose of 2 gms thrice daily.

Disclaimer:
The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.
Cultivation method: Its fruits normally ripe on October- November. Squeezed out of seeds from ripe fruits and dried it in sunlight for storing. It is possible to store of this seeds for a long time. February to March is better time for seed sowing. Germination commences within 3-4 weeks. One-two year’s old seedlings are used for transplantation in field.

Medicinal recipe:Asthma, Skin, Burning, Vomiting, Dysentry, Piles.

Nagkesar is a local name of Mesua ferrea. It is well known herb in Chhattisgarh particularly in the regions at Orissa state border. The traditional healers and senior natives of Chhattisgarh are well aware of its medicinal properties and uses. They use it alone and in combination with other herbs in treatment of many common troubles, but the traditional healers of the state are not much aware of Herbal dish Nagkesar Ke Murabba. According to the traditional healers of Bagbahera region, this dish was in use in early days and was very popular among the traditional healers. The healers were recommending this preparation as cardio-tonic. During the ethnobotanical surveys conducted in different parts of Chhattisgarh, I asked the healers about this dish but no one came forward with any information. The traditional healers of Bagbahera region are aware of its method of preparation but they have no reason explaining why this dish is not popular in present time?


Material Required
: Nagkesar fruits and Sugar.

Method of Preparation : The fruits are boiled in water. Separately, sugar is boiled in water to prepare the Chashni (Syrup). The boiled fruits are added in Chashni and the combination is kept under moonlight for one month. Once prepared in bulk, it can be used round the year.
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As per Ayurveda:It is mild ushna, laghu, tikta; subdues deranged kapha; cures diseases of urinary bladder and those caused by deranged vata; beneficial in sore throat and headache.

Parts Used: Fruits, seeds, flowers, leaves and bark.

Therapeutic Uses:

Fruits: astringent, useful in gastric troubles; seeds: oil in rheumatism and cutaneous affections;

Flowers: astringent, stomachic and expectorant; powder mixed with ghee (butter fat) applied externally in bleeding piles;
The flowers are astringent and stomachic

Buds useful in dysentery; leaves: as poultice applied on forehead in severe colds;

Bark: astringent, Sweetish, carminative, binding, cardiotonic; good in asthma answeats; cures ulcers and piles , hot ,dry, easy to digest, digestive, good for fevers, sweats, biliousness, foul breath, scabies, skin eruptions, itching, small tumours, headache, blood and heart troubles, sore throat, cough, hiccough, vomiting, thirst, dysentery, and bleeding piles

Bark is mildly astringent and feebly aromatic. Combined with ginger it is given as a sudorifie,
.In many localities they are used for cough, especially when attended with much expectoration.
A paste made of the flowers with butter and sugar is used in bleeding piles and burning of the feel.

Resources:

http://www.allayurveda.com/topic_month_february2004.htm
http://www.orissafdc.com/products_medicinal_plants.php
http://www.mapbd.com/Mpdes.htm#nageshwar

http://www.ayurvedakalamandiram.com/herbs.htm#madayantika

 

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Herbs & Plants

Wormwood

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The name of this plant derives from its bitterness, from absinthia, the Roman word for “bitter”. This property is used for providing bitter taste to some well known beverages and liquors. Wormwood has a marked tonic effect on the stomach, the gallbladder and in adjusting weak digestive problems. It is used to expel roundworms and threadworms. By improving the functions of the digestive system it helps in many conditions, including anaemia. It is also a muscle relaxer occasionally used to treat rheumatism. The leaves of wormwood have antiseptic properties which may derive from the azulenes that the plant contains.

MAIN PROPERTIES:
Bitter, carminative, muscle relaxer, antiseptic.

Wormwood has various varieties…..three most popular are described below: 1.Wormwood common, 2. Wormwood Roman 3. Wormwood Sea

1.WORMWOOD COMMON
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Botanical Name : Artemisia absinthium (LINN.)
Family: N.O. Compositae
Synonym: Green Ginger.

Common Name :Afsanteen
Parts Used: The whole herb – leaves and tops – gathered in July and August, when the plant is in flower and dried.
Habitat: Europe, Siberia, and United States of America.
The Common Wormwood held a high reputation in medicine among the Ancients. Tusser (1577), in July’s Husbandry, says:
‘While Wormwood hath seed get a handful or twaine
To save against March, to make flea to refraine:
Where chamber is sweeped and Wormwood is strowne,
What saver is better (if physick be true)
For places infected than Wormwood and Rue?
It is a comfort for hart and the braine
And therefore to have it it is not in vaine.’
Besides being strewn in chambers as Tusser recommended, it used to be laid amongstuffs and furs to keep away moths and insects.
According to the Ancients, Wormwood counteracted the effects of poisoning by hemlock, toadstools and the biting of the seadragon. The plant was of some importance among the Mexicans, who celebrated their great festival of the Goddess of Salt by a ceremonial dance of women, who wore on their heads garlands of Wormwood.

With the exception of Rue, Wormwood is the bitterest herb known, but it is very wholesome and used to be in much request by brewers for use instead of hops. The leaves resist putrefaction, and have been on that account a principal ingredient in antiseptic fomentations.

An Old Love Charm
‘On St. Luke‘s Day, take marigold flowers, a sprig of marjoram, thyme, and a little Wormwood; dry them before a fire, rub them to powder; then sift it through a fine piece of lawn, and simmer it over a slow fire, adding a small quantity of virgin honey, and vinegar. Anoint yourself with this when you go to bed, saying the following lines three times, and you will dream of your partner “that is to be”:
“St. Luke, St. Luke, be kind to me,
In dreams let me my true-love see.” ‘
Culpepper, writing of the three Wormwoods most in use, the Common Wormwood, Sea Wormwood and Roman Wormwood, tells us: ‘Each kind has its particular virtues’ . . . the Common Wormwood is ‘the strongest,’ the Sea Wormwood, ‘the second in bitterness,’ whereas the Roman Wormwood, ‘to be found in botanic gardens’ – the first two being wild – ‘joins a great deal of aromatic flavour with but little bitterness.’
The Common Wormwood grows on roadsides and waste places, and is found over the greater part of Europe and Siberia, having been formerly much cultivated for its qualities. In Britain, it appears to be truly indigenous near the sea and locally in many other parts of England and Scotland, from Forfar southwards. In Ireland it is a doubtful native. It has become naturalized in the United States.

 

Description:
It is a herbaceous perennial plant, with a hard, woody rhizome. The stems are straight, growing to 0.8-1.2 m (rarely 1.5 m) tall, grooved, branched, and silvery-green. The leaves are spirally arranged, greenish-grey above and white below, covered with silky silvery-white hairs, and bearing minute oil-producing glands; the basal leaves are up to 25 cm long, bipinnate to tripinnate with long petioles, with the cauline leaves (those on the stem) smaller, 5-10 cm long, less divided, and with short petioles; the uppermost leaves can be both simple and sessile (without a petiole). Its flowers are pale yellow, tubular, and clustered in spherical bent-down heads (capitula), which are in turn clustered in leafy and branched panicles. Flowering is from early summer to early autumn; pollination is anemophilous. The fruit is a small achene; seed dispersal is by gravity.

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It grows naturally on uncultivated, arid ground, on rocky slopes, and at the edge of footpaths and fields.

The root is perennial, and from it arise branched, firm, leafy stems, sometimes almost woody at the base. The flowering stem is 2 to 2 1/2 feet high and whitish, being closely covered with fine silky hairs. The leaves, which are also whitish on both sides from the same reason, are about 3 inches long by 1 1/2 broad, cut into deeply and repeatedly (about three times pinnatifid), the segments being narrow (linear) and blunt. The leaf-stalks are slightly winged at the margin. The small, nearly globular flowerheads are arranged in an erect, leafy panicle, the leaves on the flower-stalks being reduced to three, or even one linear segment, and the little flowers themselves being pendulous and of a greenish-yellow tint. They bloom from July to October. The ripe fruits are not crowned by a tuft of hairs, or pappus, as in the majority of the Compositae family.

The leaves and flowers are very bitter, with a characteristic odour, resembling that of thujone. The root has a warm and aromatic taste.

Cultivation: Wormwood likes a shady situation, and is easily propagated by division of roots in the autumn, by cuttings, or by seeds sown in the autumn soon after they are ripe. No further care is needed than to keep free from weeds. Plant about 2 feet apart each way.
Collect only on a dry day, after the sun has dried off the dew. Cut off the upper green portion and reject the lower parts of the stems, together with any discoloured or insect-eaten leaves. Tie loosely in bunches of uniform size and length, about six stalks to a bunch, and spread out in shape of a fan, so that the air can get to all parts. Hang over strings, in the open, on a fine, sunny, warm day, but in half-shade, otherwise the leaves will become tindery; the drying must not be done in full sunlight, or the aromatic properties will be partly lost. Aromatic herbs should be dried at a temperature of about 70 degrees. If no sun is available, the bunches may be hung over strings in a covered shed, or disused greenhouse, or in a sunny warm attic, provided there is ample ventilation, so that the moist heated air may escape. The room may also be heated with a coke or anthracite stove, care being taken that the window is kept open during the day. If after some days the leaves are crisp and the stalks still damp, hang the bunches over a stove, when the stalks will quickly finish drying. Uniformity in size in the bunches is important, as it facilitates packing. When the drying process is completed, pack away at once in airtight boxes, as otherwise the herbs will absorb about 12 per cent moisture from the air. If sold to the wholesale druggists in powdered form, rub through a sieve as soon as thoroughly dry, before the bunches have had time to absorb any moisture, and pack in tins or bottles at once.

Constituents-
: The chief constituent is a volatile oil, of which the herb yields in distillation from 0.5 to 1.0 per cent. It is usually dark green, or sometimes blue in colour, and has a strong odour and bitter, acrid taste. The oil contains thujone (absinthol or tenacetone), thujyl alcohol (both free and combined with acetic, isovalerianic, succine and malic acids), cadinene, phellandrene and pinene. The herb also contains the bitter glucoside absinthin, absinthic acid, together with tannin, resin, starch, nitrate of potash and other salts.

Therapeutic uses:
The leaves and flowering tops are gathered when the plant is in full bloom, and dried naturally or with artificial heat. Its active substances include silica, two bitter elements (absinthine and anabsinthine), thujone, tannic and resinous substances, malic acid, and succinic acid. Its use has been claimed to remedy indigestion and gastric pain, it acts as an antiseptic, and as a febrifuge. For medicinal use, the herb is used to make a tea for helping pregnant women during pain of labor. A wine can also be made by macerating the herb. It is also available in powder form and as a tincture. The oil of the plant can be used as a cardiac stimulant to improve blood circulation. Pure wormwood oil is very poisonous, but with proper dosage poses little or no danger. Wormwood is mostly a stomach medicine.

Medicinal Action and Uses: -Tonic, stomachic, febrifuge, anthelmintic.

A nervine tonic, particularly helpful against the falling sickness and for flatulence. It is a good remedy for enfeebled digestion and debility.

Preparations: Fluid extract, 1/2 to 1 drachm. Wormwood Tea, made from 1 OZ. of the herb, infused for 10 to 12 minutes in 1 pint of boiling water, and taken in wineglassful doses, will relieve melancholia and help to dispel the yellow hue of jaundice from the skin, as well as being a good stomachic, and with the addition of fixed alkaline salt, produced from the burnt plant, is a powerful diuretic in some dropsical cases. The ashes yield a purer alkaline salt than most other vegetables, except Beanstalks and Broom.

The juice of the larger leaves which grow from the root before the stalk appears has been used as a remedy for jaundice and dropsy, but it is intensely nauseous. A light infusion of the tops of the plant, used fresh, is excellent for all disorders of the stomach, creating an appetite, promoting digestion and preventing sickness after meals, but it is said to produce the contrary effect if made too strong.

The flowers, dried and powdered, are most effectual as a vermifuge, and used to be considered excellent in agues. The essential oil of the herb is used as a worm-expeller, the spirituous extract being preferable to that distilled in water. The leaves give out nearly the whole of their smell and taste both to spirit and water, but the cold water infusions are the least offensive.

The intensely bitter, tonic and stimulant qualities have caused Wormwood not only to be an ingredient in medicinal preparations, but also to be used in various liqueurs, of which absinthe is the chief, the basis of absinthe being absinthol, extracted from Wormwood. Wormwood, as employed in making this liqueur, bears also the name ‘Wermuth’ – preserver of the mind – from its medicinal virtues as a nervine and mental restorative. If not taken habitually, it soothes spinal irritability and gives tone to persons of a highly nervous temperament. Suitable allowances of the diluted liqueur will promote salutary perspiration and may be given as a vermifuge. Inferior absinthe is generally adulterated with copper, which produces the characteristic green colour.

The drug, absinthium, is rarely employed, but it might be of value in nervous diseases such as neurasthenia, as it stimulates the cerebral hemispheres, and is a direct stimulant of the cortex cerebri. When taken to excess it produces giddiness and attacks of epileptiform convulsions. Absinthium occurs in the British Pharmacopoeia in the form of extract, infusion and tincture, and is directed to be extracted also from A. maritima, the Sea Wormwood, which possesses the same virtues in a less degree, and is often more used as a stomachic than the Common Wormwood. Commercially this often goes under the name of Roman Wormwood, though that name really belongs to A. Pontica. All three species were used, as in Culpepper’s time.

Dr. John Hill (1772) recommends Common Wormwood in many forms. He says:
‘The Leaves have been commonly used, but the flowery tops are the right part. These, made into a light infusion, strengthen digestion, correct acidities, and supply the place of gall, where, as in many constitutions, that is deficient. One ounce of the Flowers and Buds should be put into an earthen vessel, and a pint and a half of boiling water poured on them, and thus to stand all night. In the morning the clear liquor with two spoonfuls of wine should be taken at three draughts, an hour and a half distance from one another. Whoever will do this regularly for a week, will have no sickness after meals, will feel none of that fulness so frequent from indigestion, and wind will be no more troublesome; if afterwards, he will take but a fourth part of this each day, the benefit will be lasting.’
He further tells us that if an ounce of these flowers be put into a pint of brandy and let to stand six weeks, the resultant tincture will in a great measure prevent the increase of gravel – and give great relief in gout. ‘The celebrated Baron Haller has found vast benefit by this; and myself have very happily followed his example.
2.WORMWOOD, ROMAN
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Botanical Name: Artemesia pontica
Family:
N.O. Compositae
Part Used: Herb.
Roman Wormwood (Artemesia Pontica) is not indigenous to this country, being a native of Southern Europe. It grows about the same height as the Common Wormwood, but has smaller and more finely cut leaves, the segments being narrower, the upper leaves more resembling those of Southernwood; the leaves are white with fine hairs on both upper and under surfaces. The flowers, which blossom in July, are numerous, at the tops of the branches, and are darker and much smaller than those of Common Wormwood.

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This is the most delicate though the least strong of the Wormwoods; the aromatic flavour with which its bitterness is mixed causes it to be employed in making the liqueur Vermuth.

Medicinally, the fresh tops are used, and also the whole herb, dried. Much of the A. Pontica in commerce is A. maritima.

Culpepper considered the Roman Wormwood ‘excellent to strengthen the stomach.’ Also that ‘the juice of the fresh tops is good against obstructions of the liver and spleen. . . . An infusion of the flowering tops strengthens digestion. A tincture is good against gravel and gives great relief in the gout.’

Dr. John Hill says of this plant that it is the ‘most delicate, but of least strength. The Wormwood wine, so famous with the Germans, is made with Roman Wormwood, put into the juice and work’d with it; it is a strong and an excellent wine, not unpleasant, yet of such efficacy to give an appetite that the Germans drink a glass with every other mouthful, and that way eat for hours together, without sickness or indigestion.’
3.WORMWOOD SEA
____________
Botanical Name:
Artemesia maritima
Family: N.O. Compositae
Synonym: Old Woman.
Parts Used: Young flowering tops and shoots.
Habitat: In Britain it is found as far-as Wigton on the West and Aberdeen on the East; also in north-east Ireland and in the Channel Islands.
The Sea Wormwood, in its many variations of form, has an extremely wide distribution in the northern hemisphere of the Old World, occurring mostly in saltish soils. It is found in the salt marshes of the British Isles, on the coasts of the Baltic, of France and the Mediterranean, and on saline soils in Hungary; thence it extends eastwards, covering immense tracts in Southern Russia, the region of the Caspian and Central Siberia to Chinese Mongolia.

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Description: It somewhat resembles Artemesia Absinthium, but is smaller. Thestems rise about a foot or 18 inches in height. The leaves are twice pinnatifid, with narrow, linear segments, and, like the whole plant, are covered on both sides with a white cottony down. The small, oblong flower-heads – each containing three to six tubular florets – are of a yellowish or brownish tint; they are produced in August and September, and are arranged in racemes, sometimes drooping, sometimes erect.

Popularly this species is called ‘Old Woman,’ in distinction to ‘Old Man’ or Southernwood, which it somewhat resembles, though it is more delicate-looking and lacks the peculiar refreshing scent of ‘Old Man.’

Dr. Hill says of this species:
‘This is a very noble bitter: its peculiar province is to give an appetite, as that of the Common Wormwood is to assist digestion; the flowery tops and the young shoots possess the virtue: the older Leaves and the Stalk should be thrown away as useless. . . . The apothecaries put three times as much sugar as of the ingredient in their Conserves; but the virtue is lost in the sweetness, those will not keep so well that have less sugar, but ’tis easy to make them fresh as they are wanted.’
The plant abounds in salt marshes in which cattle have been observed to fatten quickly, and thus the herb has acquired the reputation of being beneficial to them, but they do not eat it generally, and the richness of maritime pasturage must be regarded as the true reason of their improvement under such circumstances.

Medicinal Action and Uses: The plant possesses the same properties as the otherWormwoods, but is less powerful. It is a bitter tonic and aromatic.

Although it is not now employed in regular medical practice, it is often made use of by country people for intermittent fever, and for various other medicinal purposes instead of the true Wormwood.

Thornton, in his Family Herbal, tells us that:
‘beat up with thrice its weight of fine sugar, it is made up into a conserve ordered by the London College, and may be taken where the other preparations disgust too much.’
It acts as a tonic and is good in worm cases, and Culpepper gives the following uses for it:
‘Boiling water poured upon it produces an excellent stomachic infusion, but the best way is taking it in a tincture made with brandy. Hysteric complaints have been completely cured by the constant use of this tincture. In the scurvy and in the hypochondriacal disorders of studious, sedentary men, few things have a greater effect: for these it is best in strong infusion. The whole blood and all the juices of the body are effected by taking this herb. It is often used in medicine instead of the Roman Wormwood, though it falls far short of it in virtue.’

Resources:

http://en.wikipedia.org

www.botanical.com

Categories
Herbs & Plants News on Health & Science

Kokum to the rescue

.

A molecule in the popular spice can help prevent the spread of the AIDS virus in the human body.
The fight against the deadly human immuno deficiency virus (HIV) is all set to get a desi flavour. Indian researchers have isolated a compound from kokum  a berry widely used as a flavouring agent in Goan cuisine ” that has a remarkable anti-HIV potential. But the compound may have to cross several hurdles before it becomes a potent weapon in the war against AIDS, an epidemic that has already killed millions and may kill several millions more in the near future.

Tapas Kundu and his team at Bangalores Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) knew for at least three years that the rind of kokum (Garcinia indica, a plant indigenous to the Western Ghats) contains a wonder molecule called garcinol. Kokum is also used as a substitute for tamarind in Konkani cuisine and select dishes in Maharashtra, Gujarat and Kerala. In addition to garnishing curries and soups, it is used for its astringent, cardio-tonic, anti-allergic and digestive properties. Kokum seeds yield a unique fat that is used in making ointments, suppositories, lipsticks and chocolates.

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In 2004, Kundu’s team showed for the first time that garcinol has a unique property of impeding a human enzyme that, incidentally, is marshalled by the HIV virus for its own proliferation in the human body. So if one has a compound that inhibits this protein, called p300, one can substantially curb the multiplication of the dreaded virus to such an extent that the human immune cells can take over from there. Garcinol does possess this capability, but there is one problem: it is toxic to normal human cells which in its presence die in a few hours.

It is here that Kundu’s grounding in biochemistry was of help. Kundu, who has a doctorate in biochemistry from the Indian Institute of Science, Bangalore, chemically tweaked garcinol to create what is known as isogarcinol. Further chemical modification yielded 50 different compounds and one of these   LTK-14   was found to spare human cells but block p300.

“What is remarkable about their work is that they modified this natural molecule in such a way that it has become cell friendly,  says Udaykumar Ranga, a molecular virologist at JNCASR who specialises in HIV. Besides, LTK-14   unlike its parent compound — has the ability to cross the cell membrane with ease, he observes.

According to Kundu, the newly derived molecule was found to reduce the viral load by up to 80 per cent in the infected cells. The work was recently reported in Chemistry & Biology.  We have found that the compound inhibits all p300-mediated gene expressions,  Kundu, who has a basic degree in agriculture from Bidhan Chandra Agricultural University in Nadia, told Know How.

However, Ranga  also a co-author of the paper   thinks it’s too early to be upbeat. The molecule’s action is radically different from that of existing drugs. While anti-viral medicines target the virus itself, this one is trying to destroy a molecule in human cells whose mechanism the virus hijacks to proliferate.  It’s quite like bombing a neighbourhood where enemies are holing up. The bomb has to be dropped in such a way that it kills the maximum number of enemies with bare minimum damage to others,” Ranga explains.

A histone acetyltransferase protein, p300 has several functions in cells. A molecular switch that turns on or off a number of genes inside the cell, it’s pivotal for several key functions such as cell growth, differentiation and its eventual death. “Living cells are remarkable. Our studies have shown that when p300 is absent, others within the cells take over and carry out these tasks,” Kundu observes. On the other hand, the prominent HIV protein — known as TAT — that ensures the virus’ multiplication in the human cells can do so only if p300 is available.

Developing drugs against viruses as wily as HIV is tricky. “They are like volcanoes,” says Ranga. “While some erupt and explode, others lay latent and wait for an opportune time. No weapon in our arsenal today is capable of tackling a dormant virus.

Source: The Telegraph (Kolkata, India)

 

Categories
Herbs & Plants

Hollyhocks (Alcea Roses)

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Botanical Name: Alcea rosea
Family: Malvaceae
Genus: Alcea
Kingdom: Plantae
Order:     Malvales

The scientific name for Hollyhocks is Alcea rosea but used to go by the scientific name Althaea and is still seen that way in garden catalogs on occasion.

Common Name:Hollyhocks

Habitats: Holyhock is native to Eurasia.It grows in Woodland Garden; Sunny Edge; Dappled Shade; and in  Cultivated Beds.Hollyhocks prefer rich, well-drained soil and full sun. Light shade is tolerated but wet winter soil is not….click & see

Description:
Holyhock  is a biennial or short-lived perennial plant about 4-8′ tall. The stout central stem is unbranched or sparingly branched; it is light green, terete, and more or less hairy. The blades of the alternate leaves are up to 8″ long and across; they are palmately lobed (with 3-7 blunt lobes each) and crenate along their margins. Each leaf blade is orbicular or oval in outline and indented at the base where the petiole joins the blade. The upper surface of each leaf blade is medium green, slightly pubescent to hairless, and wrinkled from fine veins; the lower surface is light green and pubescent. The petioles of the leaves are as long or a little longer than their blades; they are light green and hairy..
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The central stem terminates in a spike-like raceme of flowers; axillary flowers are produced from the axils of the upper leaves as well. These flowers occur individually or in small clusters along the central stem; they nod sideways from short hairy pedicels. Each flower spans about 3-5″ when it is fully open; it has 5 petals, 5 sepals, 6-9 sepal-like bracts, and a columnar structure in the center with the reproductive organs (stamens toward the tip, thread-like stigmas below). The overlapping petals provide the flower with a funnelform shape; they are usually some shade of white, pink, or purplish red. The sepals are light green, ovate, and much smaller than the petals. The bracts of each flower are located underneath the sepals; they are light green, hairy, ovate, and joined together at the base. The blooming period occurs from mid-summer into the fall; a colony of plants will bloom for about 2 months. Each flower is replaced by a fruit containing a ring of 15-20 seeds (technically, a schizocarp). These seeds are oval, flattened, and notched on one side. The root system consists of a taproot. This plant spreads by reseeding itself.

Species: There are about 60 species of Alcea, including:

Alcea acaulis
Alcea biennis (syn. A. pallida)
Alcea calvertii
Alcea ficifolia — Antwerp hollyhock
Alcea flavovirens
Alcea grossheimii — Grossheim’s alcea
Alcea heldreichii
Alcea kurdica
Alcea lavateriflora
Alcea litwinowii
Alcea longipedicellata
Alcea nudiflora
Alcea pallida
Alcea rhyticarpa
Alcea rosea — common hollyhock
Alcea rugosa
Alcea setosa — bristly hollyhock
Alcea sosnovskyi
Alcea striata
Alcea sulphurea

Hardiness Zones: Hollyhocks are hardy in zones 2-10.

Uses in the Garden: Perfect for planting in the back of borders, for old cottage gardens, cut flower gardens, humming bird beds or fence borders.

Cultivation details:
Succeeds in most soils. Poor soils should be enriched with organic matter. Prefers a heavy rich soil and a sheltered sunny position.Plants are hardy to about -15°c.A very ornamental plant, it is usually grown as a biennial due to its susceptibility to the fungal disease ‘rust’. There are many named varieties.Young plants, and also the young growth in spring, are very attractive to slugs. The preference is full to partial sun, moist to mesic conditions, and a fertile loamy soil. Lower leaves will wither away during hot dry weather. Hollyhock is vulnerable to foliar disease, including rust.

Propagation:
Seed – sow April/May or August/September in pots or in situ[200, 238]. Easily grown from seed, which usually germinates in about 2 – 3 weeks at 20°c[133, 268]. When large enough to handle, prick the seedlings out into individual pots and plant them out in the summer.Division after flowering. Only use rust-free specimens.Root cuttings in December.Basal cuttings at almost any time of year

Medicinal Uses:
Antiinflammatory; Astringent; Demulcent; Diuretic; Emollient; Febrifuge.

Hollyhock is stated to be an emollient and laxative. It is used to control inflammation, to stop bed-wetting and as a mouthwash in cases of bleeding gums .

The flowers are demulcent, diuretic and emollient. They are useful in the treatment of chest complaints, and a decoction is used to improve blood circulation, for the treatment of constipation, dysmenorrhoea, haemorrhage etc. The flowers are harvested when they are open and are dried for later use.
The shoots are used to ease a difficult labour. The root is astringent and demulcent. It is crushed and applied as a poultice to ulcers. Internally, it is used in the treatment of dysentery. The roots and the flowers are used in Tibetan medicine, where they are said to have a sweet, acrid taste and a neutral potency. They are used in the treatment of inflammations of the kidneys/womb, vaginal/seminal discharge, and the roots on their own are used to treat loss of appetite.
The seed is demulcent, diuretic and febrifuge.The flowers are used in the treatment of repiratory and inflammatory ailments and the root extracts to produce marshmallow sweets.

Other Uses
Compost; Dye; Litmus; Oil; Paper.
A fibre obtained from the stems is used in papermaking. The fibres are about 1.9mm long. The stems are harvested in late summer, the leaves are removed and the stems are steamed until the fibres can be removed. The fibres are cooked with lye for 2 hours and then ball milled for 3 hours or pounded with mallets. The paper is light tan in colour.

The flowers are an alternative ingredient of ‘Quick Return’ herbal compost activator. This is a dried and powdered mixture of several herbs that can be added to a compost heap in order to speed up bacterial activity and thus shorten the time needed to make the compost.The seed contains 12% of a drying oil.The red anthocyanin constituent of the flowers is used as a litmus.A brown dye is obtained from the petals.
Hollyhocks are tolerant of black walnut toxins and, like Polemonium plants, can be planted near and around black walnut trees where other plants will not grow.

Disclaimer:
The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

Resources:
http://www.ibiblio.org/pfaf/cgi-bin/arr_html?Alcea+rosea
http://plantsbulbs.suite101.com/article.cfm/hollyhock_alcea_plant_profile
http://en.wikipedia.org/wiki/Alcea
http://www.illinoiswildflowers.info/weeds/plants/hollyhock.htm

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