Vitamine B-12 is essencial to keep fatigue and forgetfulness away.
If we feel tired even after eight solid hours of sleep, It’s not just because of the long hours we are putting in at work, it could be the sign of a deficiency too. If we also feel depressed without a reason, have a tingling sensation in our hands or feet and have noticed a recent tendency to forget things, it may be that we are lacking in Vitamin B12.
Also known as cobalamin, Vitamin B12 is one of the eight B vitamins and its role in cellular metabolism is closely intertwined with that of folate, another B vitamin.
“Over 50 per cent of Indians have B12 deficiency,” says Sadanand S. Naik, head of the department of clinical biochemistry at Pune’s KEM Hospital.
It can affect anyone and at any age. “The figure is higher among vegetarians, pregnant women (as its requirement goes up during pregnancy) and the elderly (as they do not take adequate nutrition),” says Seema Gulati, head of the nutrition research group at the National Diabetes Obesity and Cholesterol Foundation (NDOC), a Delhi-based NGO.
In all age groups, Vitamin B12 should be in the range of 200 pg/ml to 900 pg/ml of blood, where one pg or picogram is one trillionth of a gram. The early signals of a deficiency are anaemia, lethargy, joint pain, loss of memory and laziness. So if we are being plagued by more than one of these symptoms, we should see doctor and get ourselves tested.
Vitamin B12 deficiency is becoming a growing health concern across the world. An article published this year in the journal Nature Reviews – co-authored by Dr Ralph Green of the US, and a group of 14 international experts – states, “Deficiency of B12 is emerging as a public health concern in many low-income countries. A World Health Organization consultation identified infants, preschool children and pregnant and lactating women as the most vulnerable groups.”
The lack of Vitamin B12 for a sufficiently long period of time can lead to sensory and motor disturbances, ataxia leading to lack of voluntary coordination of muscle movements, and cognitive decline leading to dementia and psychiatric disorders. “Advanced Vitamin B12 deficiency could also lead to delirium and paranoia,” says Bangalore-based biological scientist Sujata Kelkar Shetty.
Low B12 levels could even spark off coronary artery disease, suggests a 2009 report of the US-based National Center for Biotechnology Information. It states that the incidence of coronary artery disease is increasing at an alarming rate, especially in developing countries such as India. “This may be due to deficiency of vitamin B12, a micronutrient, sourced only from animal products,” it adds.
There also seems to be a connection between lack of Vitamin B12 and the health of the thyroid gland. “Vitamin B12 deficiency and hypothyroidism are inter-related among young females,” says KEM’s Naik. “This is partly due to vegetarianism, a sedentary lifestyle and not enough exposure to sunlight.”
Incidentally, sunlight helps us make Vitamin D. So there is always a possibility that we may be deficient in both vitamins B12 and D3. “Prolonged D and B12 deficiency leads to impaired bone mineralisation, anaemia and neuro-cognitive disorders. Notable D and B12 deficiency prevails in epidemic proportions all over the Indian subcontinent,” reveals Naik.
Unlike Vitamin D, our body cannot make Vitamin B12. “So we have to get it from animal-based foods (dairy or meat) or from supplements [for vegetarians]. And we should do that on a regular basis, because our body cannot store vitamin B12 for a long time,” Gulati says. Since this vitamin is water soluble, any excess amount flows out of the body.
Ensuring we take in enough Vitamin B12 is sometimes not enough, especially if our stomach lining has been compromised as that impairs its absorption of the vitamin. This can happen in certain gastric ailments as well as in certain autoimmune diseases such as Crohn’s. Consuming too much alcohol can also increase your risk of Vitamin B12 deficiency as it may lead to severe depletion of bodily stores of the vitamin. Chronic alcoholism also damages the lining of the stomach and intestines, which impairs absorption.
If we are found to have very low levels of B12 then the immediate relief is injectables. After taking a shot every day for five days, we will then be prescribed pills. There are, however, exceptions. “In pernicious anaemia, Vitamin B12 deficiency is persistent, and long-term injectable B12 is warranted,” says Gulati.
So,it is advicible not to wait for a shot when there are mouthful of delicious food that can give the same results.
AFA, Algae, Algas Verdiazul, Algues Bleu-Vert, Algues Bleu-Vert du Lac Klamath, Anabaena, Aphanizomenon flos-aquae, Arthrospira maxima, Arthrospira platensis, BGA, Blue Green Algae, Blue-Green Micro-Algae, Cyanobacteria, Cyanobactérie, Cyanophycée, Dihe, Espirulina, Hawaiian Spirulina, Klamath, Klamath Lake Algae, Lyngbya wollei, Microcystis aeruginosa, Microcystis wesenbergii, Nostoc ellipsosporum, Spirulina Blue-Green Algae, Spirulina Fusiformis, Spirulina maxima, Spirulina platensis, Spirulina pacifica, Spiruline, Spiruline d’Hawaii, Tecuitlatl.
Spirulina is obtained from a plant in form of blue-green algae that springs from warm, fresh water bodies………..CLICK & SEE
Spirulina is a cyanobacterium that can be consumed by humans and other animals. There are two species, Arthrospira platensis and Arthrospira maxima.
Arthrospira is cultivated worldwide; used as a dietary supplement as well as a whole food; and is also available in tablet, flake and powder form. It is also used as a feed supplement in the aquaculture, aquarium and poultry industries.
Blue-green algae have a high protein, iron, and other mineral content which is absorbed when taken orally. Blue-green algae are being researched for their potential effects on the immune system, swelling (inflammation), and viral infections.
Chlorella is another form of algae that is sometimes confused with spirulina. The fundamental difference between spirulina and chlorella is that spirulina is many thousands of years older and does not possess the hard cell wall that makes chlorella closer to being a plant than algae.
Chlorella is an excellent way to detoxify our body from mercury, which most of you are contaminated with if you’ve ever had dental fillings, received a vaccine, used certain types of cookware or eaten fish. Spirulina simply is unable to remove heavy metals like chlorella does, as it lacks a cell membrane.
Chlorella has also been proven to be of benefit to those who suffer from degenerative disease. This report, however, will focus on the specific benefits that can be attributed to spirulina in particular.
“Blue-green algae” describes a large and diverse group of simple, plant-like organisms found in salt water and some large fresh water lakes.
Blue-green algae products are used for many conditions, but so far, there isn’t enough scientific evidence to determine whether or not they are effective for any of them.
Blue-green algae are used as a source of dietary protein, B-vitamins, and iron. They are also used for weight loss, attention deficit-hyperactivity disorder (ADHD), hayfever, diabetes, stress, fatigue, anxiety, depression, and premenstrual syndrome (PMS) and other women’s health issues.
Some people use blue-green algae for treating precancerous growths inside the mouth, boosting the immune system, improving memory, increasing energy and metabolism, lowering cholesterol, preventing heart disease, healing wounds, and improving digestion and bowel health.
Blue-green algae are commonly found in tropical or subtropical waters that have a high-salt content, but some types grow in large fresh water lakes. The natural color of these algae can give bodies of water a dark-green appearance. The altitude, temperature, and sun exposure where the blue-green algae are grown dramatically influence the types and mix of blue-green algae in the water.
Some blue-green algae products are grown under controlled conditions. Others are grown in a natural setting, where they are more likely to be contaminated by bacteria, liver poisons (microcystins) produced by certain bacteria, and heavy metals. Choose only products that have been tested and found free of these contaminants.
You may have been told that blue-green algae are an excellent source of protein. But, in reality, blue-green algae is no better than meat or milk as a protein source and costs about 30 times as much per gram.
Dried spirulina contains about 60% (51–71%) protein. It is a complete protein containing all essential amino acids, though with reduced amounts of methionine, cysteine and lysine when compared to the proteins of meat, eggs and milk. It is, however, superior to typical plant protein, such as that from legumes.
The U.S. National Library of Medicine said that spirulina was no better than milk or meat as a protein source, and was approximately 30 times more expensive per gram
Spirulina’s lipid content is about 7% by weight, and is rich in gamma-linolenic acid (GLA), and also provides alpha-linolenic acid (ALA), linoleic acid (LA), stearidonic acid (SDA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and arachidonic acid (AA). Spirulina contains vitamins B1 (thiamine), B2 (riboflavin), B3 (nicotinamide), B6 (pyridoxine), B9 (folic acid), vitamin C, vitamin A, and vitamin E. It is also a source of potassium, calcium, chromium, copper, iron, magnesium, manganese, phosphorus, selenium, sodium, and zinc. Spirulina contains many pigments which may be beneficial and bioavailable, including beta-carotene, zeaxanthin, 7-hydroxyretinoic acid, isomers, chlorophyll-a, xanthophyll, echinenone, myxoxanthophyll, canthaxanthin, diatoxanthin, 3′-hydroxyechinenone, beta-cryptoxanthin, and oscillaxanthin, plus the phycobiliproteins c-phycocyanin and allophycocyanin.
Vitamin B12 controversy:
Spirulina is not considered to be a reliable source of Vitamin B12. Spirulina supplements contain predominantly pseudovitamin B12, which is biologically inactive in humans. Companies which grow and market spirulina have claimed it to be a significant source of B12 on the basis of alternative, unpublished assays, although their claims are not accepted by independent scientific organizations. The American Dietetic Association and Dietitians of Canada in their position paper on vegetarian diets state that spirulina cannot be counted on as a reliable source of active vitamin B12. The medical literature similarly advises that spirulina is unsuitable as a source of B12.
Spirulina Helped Save Millions from Arsenic Poisoning:
Bangladeshi researchers conducted a three-month-hospital-based study, where spirulina was given to 33 patients while 17 received placebo doses. 82 percent of those taking spirulina showed tremendous improvement.
An Immune-System Power-Boost — Spirulina’s Impact on Candida and AIDS:
According to a study done by the Department of Aquataculture in Taiwan,4 spirulina shows significant immune-boosting properties. Researchers exposed white shrimp to seawater containing a hot-water extract of spirulina before transferring them to seawater with a pH level of 6.8. The control group was not exposed to spirulina.
The shrimp exposed to the spirulina seawater showed a faster and more promising recovery rate to the high levels of pH than those not given the dose of spirulina first.
Now, let’s take a look at what this immune-system boosting power can mean for us:
If we have an autoimmune disease such as Crohn’s disease, chronic fatigue syndrome, Lupus or fibromyalgia, chronic candida yeast can both cause and worsen your symptoms. Spirulina has been shown to encourage and support the growth of healthy bacterial flora in our gut, which can help keep candida overgrowth under control.
HIV and AIDS:
Drugs such as AZT used to treat HIV and AIDS patients can actually cause the symptoms they are supposed to cure. However, spirulina has been shown to help inactivate the human immunodeficiency virus associated with HIV and AIDS.
Millions of people are allergic to pollen, ragweed, dust, mold, pet dander, and a myriad other environmental contaminants, ensuring the makers of Kleenex will always stay in business.
Unfortunately, many people who have allergic rhinitis treat it with prescription and over-the-counter (OTC) drugs that often do more harm than good. Antihistamines are designed to suppress our immune system, which leads to decreased resistance to disease and dependence on the drug. Certain asthma drugs have been linked to serious side effects as well.
This is where natural methods such as the use of spirulina come in. According to one study, patients treated with spirulina reported relief of symptoms commonly associated with allergic rhinitis, such as nasal discharge and congestion, sneezing and itching, when given spirulina.
Blood Pressure Balancing:
According to a study done by the Department of Biochemistry in Mexico,7 4.5 grams of spirulina given each day was shown to regulate blood pressure among both women and men ages 18-65 years with no other dietary changes made during the six weeks the experiment was run.
Lowers Stroke Risk:
In a study done at the Institute of Pharmaceutical Technology in India, it was found that a dosage of 180mg/kg of spirulina had a protective effect on the brain and nervous system of rats exposed to high amounts of free radicals, compared to rats not given the spirulina before the experiment. This lab test shows the promising effect of spirulina on stroke prevention.
Helps Reduce Cancer Risk:
According to a study done in China,10 selenium-infused spirulina inhibited the growth of MCF-7 breast cancer cells.
Potential Adverse Reactions:
Spirulina is a safe source of protein, nutrients, vitamins, and minerals that has been used for centuries. Though there are no known side effects associated with spirulina, our body may react to it based on our current state of health. Let’s take a look at some of those reactions, what they mean, and what you can do to alleviate them.
The most prominent reactions one may experience are: *Slight Fever –– The high protein content in spirulina increases metabolism, which may elevate body temperature.
*Dark Green Waste Matter — Spirulina can remove accumulated waste product in our colon, which may cause darker stool. Also, spirulina is high in chlorophyll. This will also turn waste matter green.
*Excessive Passing of Gas — This may indicate that your digestive system is not functioning properly or you have an extreme build-up of gas.
*Feelings of Excitement — Our body is converting protein into heat energy, which may cause temporary feelings of restlessness.
*Breakouts and Itchy Skin — This is caused by colon cleansing process and is only temporary.
*Sleepiness— This is caused by the detoxification process and may indicate our body is exhausted and needs better rest.
Remember, our body may go through an adjustment period with spirulina, and our best bet to reduce reaction is to dose gradually to see how our body will react. Water intake should be increased and , stress levels should be reduced, we should eat according to our nutritional type, and get plenty of rest.
Important Contraindications for Spirulina:
Even though spirulina is entirely natural and generally considered a healthful food, there are some contraindications we need to be aware of. No one should take spirulina if he or she has a severe seafood or iodine allergy. And, if one is pregnant or nursing or have hyperthyroidism, it is adviced to consult with the healthcare provider before taking spirulina.
Zinc is a kind of metallic chemical element. It is considered to be a transition metal, similar to nickel and mercury. It has the chemical symbol of ZN with an atomic number of 30. In its pure form it has a kind of light blue color. It tends to be quite brittle at room temperature but, once it is heated, it transforms into something very soft and easy to shape. In fact, it is often added to other metals in order to make them more malleable....CLICK & SEE
People have been using zinc for centuries. The ancient Hindi civilization were the first to find many applications for it. By the 1500s, though, it made its way to Europe via trade. There, it was considered rare and was quite expensive to obtain. Today, however, people have found many zinc sources and it is considered a relatively abundant chemical.
Zinc is used to make metal alloys and is usually an ingredient in making batteries and coins. Zinc oxide, on the other hand, is an ingredient in sun screen. Zinc is also needed by the body. An average person needs 11 mg of zinc ever day; lack of zinc can lead to hair loss and diarrhea. Too much zinc, on the other hand, can cause anemia. Luckily it is possible to get the recommended daily allowance of zinc through food. Some foods that are rich in zinc are seeds and whole grains. However, it is also possible to get zinc supplements, or on the other hand, multi-vitamins that are enriched with zinc.
Zinc is included in most single tablet over-the-counter daily vitamin and mineral supplements. It is believed to possess antioxidant properties, which protect against accelerated aging of the skin and muscles of the body, although studies differ as to its effectiveness. Zinc also helps speed up the healing process after an injury.
The efficacy of zinc compounds when used to reduce the duration or severity of cold symptoms is controversial. Zinc gluconate glycine and zinc acetate are used in throat lozenges or tablets to reduce the duration and the severity of cold symptoms. Preparations include zinc oxide, zinc acetate, and zinc gluconate.
Zinc preparations can protect against sunburn in the summer and windburn in the winter. Applied thinly to a baby’s diaper area (perineum) with each diaper change, it can protect against diaper rash.
The Age-Related Eye Disease Study determined that zinc can be part of an effective treatment for age-related macular degeneration. Zinc supplementation is an effective treatment for acrodermatitis enteropathica, a genetic disorder affecting zinc absorption that was previously fatal to babies born with it.
Zinc lactate is used in toothpaste to prevent halitosis. Zinc pyrithione is widely applied in shampoos because of its anti-dandruff function Zinc ions are effective antimicrobial agents even at low concentrations. Gastroenteritis is strongly attenuated by ingestion of zinc, and this effect could be due to direct antimicrobial action of the zinc ions in the gastrointestinal tract, or to the absorption of the zinc and re-release from immune cells (all granulocytes secrete zinc), or both
Zinc is an essential trace element, necessary for plants, animals, and microorganisms. Zinc is found in nearly 100 specific enzymes (other sources say 300), serves as structural ions in transcription factors and is stored and transferred in metallothioneins. It is “typically the second most abundant transition metal [ sic ] in organisms” after iron and it is the only metal which appears in all enzyme classes.
In proteins, Zn ions are often coordinated to the amino acid side chains of aspartic acid, glutamic acid, cysteine and histidine. The theoretical and computational description of this zinc binding in proteins (as well as that of other transition metals) is difficult.
There are 2–4 grams of zinc distributed throughout the human body. Most zinc is in the brain, muscle, bones, kidney, and liver, with the highest concentrations in the prostate and parts of the eye. Semen is particularly rich in zinc, which is a key factor in prostate gland function and reproductive organ growth.
In humans, zinc plays “ubiquitous biological roles”. It interacts with “a wide range of organic ligands”, and has roles in the metabolism of RNA and DNA, signal transduction, and gene expression. It also regulates apoptosis. A 2006 study estimated that about 10% of human proteins (2800) potentially bind zinc, in addition to hundreds which transport and traffic zinc; a similar in silico study in the plant Arabidopsis thaliana found 2367 zinc-related proteins.
In the brain, zinc is stored in specific synaptic vesicles by glutamatergic neurons and can “modulate brain excitability”. It plays a key role in synaptic plasticity and so in learning. However it has been called “the brain’s dark horse” since it also can be a neurotoxin, suggesting zinc homeostasis plays a critical role in normal functioning of the brain and central nervous system
Zinc is a good Lewis acid, making it a useful catalytic agent in hydroxylation and other enzymatic reactions. The metal also has a flexible coordination geometry, which allows proteins using it to rapidly shift conformations to perform biological reactions. Two examples of zinc-containing enzymes are carbonic anhydrase and carboxypeptidase, which are vital to the processes of carbon dioxide (CO2) regulation and digestion of proteins, respectively. click & see
In vertebrate blood, carbonic anhydrase converts CO2 into bicarbonate and the same enzyme transforms the bicarbonate back into CO2 for exhalation through the lungs. Without this enzyme, this conversion would occur about one million times slower at the normal blood pH of 7 or would require a pH of 10 or more. The non-related ?-carbonic anhydrase is required in plants for leaf formation, the synthesis of indole acetic acid (auxin) and anaerobic respiration (alcoholic fermentation).
Carboxypeptidase cleaves peptide linkages during digestion of proteins. A coordinate covalent bond is formed between the terminal peptide and a C=O group attached to zinc, which gives the carbon a positive charge. This helps to create a hydrophobic pocket on the enzyme near the zinc, which attracts the non-polar part of the protein being digested.
Zinc serves a purely structural role in zinc fingers, twists and clusters. Zinc fingers form parts of some transcription factors, which are proteins that recognize DNA base sequences during the replication and transcription of DNA. Each of the nine or ten Zn2+ ions in a zinc finger helps maintain the finger’s structure by coordinately binding to four amino acids in the transcription factor. The transcription factor wraps around the DNA helix and uses its fingers to accurately bind to the DNA sequence.
In blood plasma, zinc is bound to and transported by albumin (60%, low-affinity) and transferrin (10%). Since transferrin also transports iron, excessive iron reduces zinc absorption, and vice-versa. A similar reaction occurs with copper. The concentration of zinc in blood plasma stays relatively constant regardless of zinc intake. Cells in the salivary gland, prostate, immune system and intestine use zinc signaling as one way to communicate with other cells.
Zinc may be held in metallothionein reserves within microorganisms or in the intestines or liver of animals. Metallothionein in intestinal cells is capable of adjusting absorption of zinc by 15–40%. However, inadequate or excessive zinc intake can be harmful; excess zinc particularly impairs copper absorption because metallothionein absorbs both metals
Foods and spices containing zincIn the U.S., the Recommended Dietary Allowance (RDA) is 8 mg/day for women and 11 mg/day for men. Median intake in the U.S. around 2000 was 9 mg/day for women and 14 mg/day in men. Red meats, especially beef, lamb and liver have some of the highest concentrations of zinc in food.
The concentration of zinc in plants varies based on levels of the element in soil. When there is adequate zinc in the soil, the food plants that contain the most zinc are wheat (germ and bran) and various seeds (sesame, poppy, alfalfa, celery, mustard). Zinc is also found in beans, nuts, almonds, whole grains, pumpkin seeds, sunflower seeds and blackcurrant.
Other sources include fortified food and dietary supplements, which come in various forms. A 1998 review concluded that zinc oxide, one of the most common supplements in the United States, and zinc carbonate are nearly insoluble and poorly absorbed in the body. This review cited studies which found low plasma zinc concentrations after zinc oxide and zinc carbonate were consumed compared with those seen after consumption of zinc acetate and sulfate salts. However, harmful excessive supplementation is a problem among the relatively affluent, and should probably not exceed 20 mg/day in healthy people, although the U.S. National Research Council set a Tolerable Upper Intake of 40 mg/day.
For fortification, however, a 2003 review recommended zinc oxide in cereals as cheap, stable, and as easily absorbed as more expensive forms. A 2005 study found that various compounds of zinc, including oxide and sulfate, did not show statistically significant differences in absorption when added as fortificants to maize tortillas. A 1987 study found that zinc picolinate was better absorbed than zinc gluconate or zinc citrate. However, a study published in 2008 determined that zinc glycinate is the best absorbed of the four dietary supplement types available.
Zinc deficiency is usually due to insufficient dietary intake, but can be associated with malabsorption, acrodermatitis enteropathica, chronic liver disease, chronic renal disease, sickle cell disease, diabetes, malignancy, and other chronic illnesses. Symptoms of mild zinc deficiency are diverse. Clinical outcomes include depressed growth, diarrhea, impotence and delayed sexual maturation, alopecia, eye and skin lesions, impaired appetite, altered cognition, impaired host defense properties, defects in carbohydrate utilization, and reproductive teratogenesis. Mild zinc deficiency depresses immunity, although excessive zinc does also. Animals with a diet deficient in zinc require twice as much food in order to attain the same weight gain as animals given sufficient zinc.
Groups at risk for zinc deficiency include the elderly, vegetarians, and those with renal insufficiency. The zinc chelator phytate, found in seeds and cereal bran, can contribute to zinc malabsorption in those with heavily vegetarian diets. There is a paucity of adequate zinc biomarkers, and the most widely used indicator, plasma zinc, has poor sensitivity and specificity. Diagnosing zinc deficiency is a persistent challenge.
Nearly two billion people in the developing world are deficient in zinc. In children it causes an increase in infection and diarrhea, contributing to the death of about 800,000 children worldwide per year. The World Health Organization advocates zinc supplementation for severe malnutrition and diarrhea. Zinc supplements help prevent disease and reduce mortality, especially among children with low birth weight or stunted growth. However, zinc supplements should not be administered alone, since many in the developing world have several deficiencies, and zinc interacts with other micronutrients.
Zinc deficiency is crop plants’ most common micronutrient deficiency; it is particularly common in high-pH soils. Zinc-deficient soil is cultivated in the cropland of about half of Turkey and India, a third of China, and most of Western Australia, and substantial responses to zinc fertilization have been reported in these areas. Plants that grow in soils that are zinc-deficient are more susceptible to disease. Zinc is primarily added to the soil through the weathering of rocks, but humans have added zinc through fossil fuel combustion, mine waste, phosphate fertilizers, limestone, manure, sewage sludge, and particles from galvanized surfaces. Excess zinc is toxic to plants, although zinc toxicity is far less widespread.
Although zinc is an essential requirement for good health, excess zinc can be harmful. Excessive absorption of zinc suppresses copper and iron absorption. The free zinc ion in solution is highly toxic to plants, invertebrates, and even vertebrate fish. The Free Ion Activity Model is well-established in the literature, and shows that just micromolar amounts of the free ion kills some organisms. A recent example showed 6 micromolar killing 93% of all Daphnia in water.
The free zinc ion is a powerful Lewis acid up to the point of being corrosive. Stomach acid contains hydrochloric acid, in which metallic zinc dissolves readily to give corrosive zinc chloride. Swallowing a post-1982 American one cent piece (97.5% zinc) can cause damage to the stomach lining due to the high solubility of the zinc ion in the acidic stomach.
There is evidence of induced copper deficiency at low intakes of 100–300 mg Zn/day; a recent trial had higher hospitalizations for urinary complications compared to placebo among elderly men taking 80 mg/day. The USDA RDA is 15 mg Zn/day. Even lower levels, closer to the RDA, may interfere with the utilization of copper and iron or adversely affect cholesterol. Levels of zinc in excess of 500 ppm in soil interfere with the ability of plants to absorb other essential metals, such as iron and manganese. There is also a condition called the zinc shakes or “zinc chills” that can be induced by the inhalation of freshly formed zinc oxide formed during the welding of galvanized materials.
The U.S. Food and Drug Administration (FDA) has stated that zinc damages nerve receptors in the nose, which can cause anosmia. Reports of anosmia were also observed in the 1930s when zinc preparations were used in a failed attempt to prevent polio infections. On June 16, 2009, the FDA said that consumers should stop using zinc-based intranasal cold products and ordered their removal from store shelves. The FDA said the loss of smell can be life-threatening because people with impaired smell cannot detect leaking gas or smoke and cannot tell if food has spoiled before they eat it. Recent research suggests that the topical antimicrobial zinc pyrithione is a potent heat shock response inducer that may impair genomic integrity with induction of PARP-dependent energy crisis in cultured human keratinocytes and melanocytes.
In 1982, the United States Mint began minting pennies coated in copper but made primarily of zinc. With the new zinc pennies, there is the potential for zinc toxicosis, which can be fatal. One reported case of chronic ingestion of 425 pennies (over 1 kg of zinc) resulted in death due to gastrointestinal bacterial and fungal sepsis, while another patient, who ingested 12 grams of zinc, only showed lethargy and ataxia (gross lack of coordination of muscle movements). Several other cases have been reported of humans suffering zinc intoxication by the ingestion of zinc coins.
Pennies and other small coins are sometimes ingested by dogs, resulting in the need for medical treatment to remove the foreign body. The zinc content of some coins can cause zinc toxicity, which is commonly fatal in dogs, where it causes a severe hemolytic anemia, and also liver or kidney damage; vomiting and diarrhea are possible symptoms. Zinc is highly toxic in parrots and poisoning can often be fatal. The consumption of fruit juices stored in galvanized cans has resulted in mass parrot poisonings with zinc
You may click to see :Use Zinc For Cold & Flue
In the recent years we have placed Vitamine C in the back seat with the advent of many newerantioxidants, but that doesn’t make it any less important. Vitamin C is clearly the “GRANDFATHER” of the traditional antioxidants we know of, and its potent health benefits have been clearly established.
Dr. Ronald Hunninghake is an internationally recognized expert on this vitamin. He got his start in this field about 22 years ago when he joined Dr. Hugh Riordan, who conducted research on intravenous (I.V.) vitamin C for cancer patients. His clinic is the successor to Linus Pauling and his work on vitamin C, and there is likely no clinic in the world with as much experience as his.
Dr. Ronald Hunninghake is an internationally recognized expert on vitamin C who has personally supervised more than 60,000 intravenous (IV) vitamin C administrations.
In this interview, Dr. Hunninghake shares his experience with this important modality.
Propolis is a resinous mixture that honey bees collect from tree buds, sap flows, or other botanical sources. It is used as a sealant for unwanted open spaces in the hive. Propolis is used for small gaps (approximately 6 millimeters (0.2 in) or less), while larger spaces are usually filled with beeswax. Its color varies depending on its botanical source, the most common being dark brown. Propolis is sticky at and above room temperature (20° Celsius). At lower temperatures it becomes hard and very brittle. Clic k to see the picture
Propolis is a sticky resin that seeps from the buds of some trees and oozes from the bark of other trees, chiefly conifers. The bees gather propolis, sometimes called bee glue, and carry it home in their pollen baskets. They blend it with wax flakes secreted from special glands on their abdomens. Propolis is used to slickly line the interior of brood cells in preparation for the queen’s laying of eggs, a most important procedure. With its antiseptic properties, this propolis lining insures a hospital-clean environment for the rearing of brood.
For centuries, beekeepers assumed that bees sealed the beehive with propolis to protect the colony from the elements, such as rain and cold winter drafts. However, 20th century research has revealed that bees not only survive, but also thrive, with increased ventilation during the winter months throughout most temperate regions of the world.
1.reinforce the structural stability of the hive
3.make the hive more defensible by sealing alternate entrances
4.prevent diseases and parasites from entering the hive, and to inhibit bacterial growth
5.prevent putrefaction within the hive. Bees usually carry waste out of and away from the hive. However if a small lizard or mouse, for example, found its way into the hive and died there, bees may be unable to carry it out through the hive entrance. In that case, they would attempt instead to seal the carcass in propolis, essentially mummifying it and making it odorless and harmless. Click to see the picture
Constituents: Chemically speaking, propolis is a very complex mixture. Its chemical elements vary according to its source. Colors range from golden brown to brownish green to reddish brown to blackish brown. A broad analysis reveals approximately 55 percent resinous compounds and balsam, 30 percent beeswax, 10 percent ethereal and aromatic oils, and 5 percent bee pollen. Many flavonols contribute to propolis. Other components include cinnamic acid, cinnamyl alcohol, vanillin, caffeic acid, tetochrysin, isalpinin, pinocembrin, chrysin, galangin, and ferulic acid.
The composition of propolis varies from hive to hive, from district to district, and from season to season. Normally it is dark brown in color, but it can be found in green, red, black and white hues, depending on the sources of resin found in the particular hive area. Honey bees are opportunists, gathering what they need from available sources, and detailed analyses show that the chemical composition of propolis varies considerably from region to region, along with the vegetation. In northern temperate climates, for example, bees collect resins from trees, such as poplars and conifers (the biological role of resin in trees is to seal wounds and defend against bacteria, fungi and insects). Poplar resin is rich in flavonoids. “Typical” northern temperate propolis has approximately 50 constituents, primarily resins and vegetable balsams (50%), waxes (30%), essential oils (10%), and pollen (5%). In neotropical regions, in addition to a large variety of trees, bees may also gather resin from flowers in the genera Clusia and Dalechampia, which are the only known plant genera that produce floral resins to attract pollinators. Clusia resin contains polyprenylated benzophenones. In some areas of Chile, propolis contains viscidone, a terpene from Baccharis shrubs, and in Brazil, naphthoquinone epoxide has recently isolated from red propolis, and prenylated acids such as 4-hydroxy-3,5-diprenyl cinnamic acid have been documented. An analysis of propolis from Henan, China found sinapic acid, isoferulic acid, caffeic acid and chrysin, with the first three compounds demonstrating anti-bacterial properties. Also, Brazilian red propolis (largely derived from Dalbergia ecastaphyllum plant resin) has high relative percentages of the isoflavonoids 3-Hydroxy-8,9-dimethoxypterocarpan and medicarpin.
Occasionally worker bees will even gather various caulking compounds of human manufacture, when the usual sources are more difficult to obtain. The properties of the propolis depend on the exact sources used by each individual hive; therefore any potential medicinal properties that may be present in one hive’s propolis may be absent from another’s, and the distributors of propolis products cannot control such factors. This may account for the many and varied claims regarding medicinal properties, and the difficulty in replicating previous scientific studies investigating these claims. Even propolis samples taken from within a single colony can vary, making controlled clinical tests difficult, and the results of any given study cannot be reliably extrapolated to propolis samples from other areas.
Properties : Propolis is another medicinal marvel from the beehive. Research shows it offers antiseptic, antibiotic, antibacterial, antifungal, and even antiviral properties. Propolis is Nature‘s premiere preventive. It is so powerful in action, it is often called Russian penicillin in acknowledgement of the extensive research the Russians have mounted on this wonder worker from the bees. Propolis demonstrates strong antimicrobial properties against various bacterial and fungal infestations. Even streptococcus bacteria have been shown sensitive to propolis.
Medicinal Uses: Nature’s Preventive Medicine : Propolis has been justly called Nature’s premier preventive. The immune system is supported and strengthened by the ingestion of propolis. Modern scientific studies indicate that those who take propolis regularly escape winter colds and sore throats and seem to develop a natural immunity to common viruses, including the various strains of flu.
Chemical antibiotics destroy all bacteria in the body, both the friendly, (necessary flora required for healthy functioning in the entire gastrointestinal tract) and the bad intestinal flora. An individual who constantly takes prescribed antibiotics for one condition after another soon learns to his sorrow that the drugs may no longer work as well as they once did. As invading bacteria get “smarter,” the drugs become less and less effective.
Propolis, the natural antibiotic, works against harmful bacteria without destroying the friendly bacteria the body needs. Propolis has also been proven effective against strains of bacteria that resist chemical antibiotics.
The field of influence of propolis is extremely broad. It includes cancer, infection of the urinary tract, swelling of the throat, gout, open wounds, sinus congestion, colds, influenza, bronchitis, gastritis, diseases of the ears, periodontal disease, intestinal infections, ulcers, eczema eruptions, pneumonia, arthritis, lung disease, stomach virus, headaches, Parkinson’s disease, bile infections, sclerosis, circulation deficiencies, warts, conjunctivitis, and hoarseness.
Propolis helps regulate hormones and is an antibiotic substance that stimulates the natural resistance of the body. Propolis may be used by everyone, sick or healthy, as a means of protection against microorganisms. Propolis is also efficient against conditions caused by bacteria, viruses, or different fungi. Propolis cures many diseases because it is a special natural substance with strong effect. You may use it as part of your daily program of supplementation. It has helped the bee society survive and thrive for over 45 million years. It may well help you survive … for a long time!
In musical instruments
Propolis is used by certain music instrument makers to enhance the appearance of the wood grain. It is a component of some varnishes and was reportedly used by Antonio Stradivari.
Propolis is used by some chewing gum manufacturers to make Propolis Gum.