Ailmemts & Remedies

Bowen’s Disease

Bowen’s disease (BD) is a sunlight-induced skin disease, considered either as an early stage or intraepidermal form of squamous cell carcinoma. It was named after Dr John T. Bowen, the doctor who first described it in 1912.


Bowen’s disease is also called squamous cell carcinoma in situ (SCC in situ), is a form of skin cancer. The term “in situ” added on the end tells us that this is a surface form of skin cancer. “Invasive” squamous cell carcinomas are the type that grow inward and may spread. SCC in situ is also known as Bowen’s disease after the doctor who first described it almost 100 years ago.

Causes of BD include solar damage, arsenic, immunosuppression (including AIDS), viral infection (human papillomavirus or HPV) and chronic skin injury and dermatoses.

Like other forms of skin cancer, SCC in situ is mainly caused by chronic sun exposure and aging. There are two other less important causes which are unique to SCC in situ. The wart virus that causes cervical cancer (HPV 16) is often found to be infecting SCC in situ. It is thought that infection with this virus is one of the reasons why two people may have the same amount of sun damage, but only one keeps getting skin cancers. The other factor that causes SCC in situ is arsenic, the same poison made famous by the play “Arsenic and Old Lace” and the Russian villain Rasputin. Arsenic contaminated some old water wells, and also many years ago was used in some medical elixirs. People with mild Arsenic poisoning didn’t die, but tend to develop cancers, both of the skin and internally. For a time it was thought that SCC in situ was a sign that cancer was going to develop internally, until it was discovered that was a false impression caused by arsenic poisoning.

Signs and symptoms:
Bowen’s disease typically presents as a gradually enlarging, well demarcated erythematous plaque with an irregular border and surface crusting or scaling. BD may occur at any age in adults but is rare before the age of 30 years – most patients are aged over 60. Any site may be affected, although involvement of palms or soles is uncommon. BD occurs predominantly in women (70-85% of cases); about three-quarters of patients have lesions on the lower leg (60-85%), usually in previously or presently sun-exposed areas of skin. A persistent progressive non-elevated red scaly or crusted plaque which is due to an intradermal carcinoma and is potentially malignant. Atypical squamous (resembling fish scales) cells proliferate through the whole thickness of the epidermis. The lesions may occur anywhere on the skin surface or on mucosal surfaces. The cause most frequently found is trivalent arsenic compounds. Freezing, cauterization or diathermy coagulation is often effective treatment.

SCC in situ is usually a red, scaly patch. It tends to be seen on areas frequently exposed to the sun. Some itch, crust or ooze, but most have no particular feeling. SCC in situ may be mistaken for rashes, eczema, fungus or psoriasis. Sometimes they are brown and look like a keratosis or a melanoma. Because of this, a biopsy must usually be done to confirm the diagnosis.

Photodynamic therapy (PDT), Cryotherapy (freezing) or local chemotherapy (with 5-fluorouracil) are favored by some clinicians over excision. Because the cells of Bowen’s disease have not invaded the dermis, it has a much better prognosis than invasive squamous cell carcinoma.

The simplest and most common treatment for smaller SCC in situ is surgical excision. The standard practice is to remove about a quarter inch beyond the edge of the cancer. Larger ones can also be excised, but Mohs surgery may be needed. It offers the highest cure rate of all treatment methods.

For those not up to surgery, there are some choices. SCC in situ can be burned off by several methods. These are “curettage and electrodessication”, liquid nitrogen cryotherapy and laser destruction. These heal with similar scars.

X-ray or grenz ray radiation can be given to poor surgical candidates or patients with multiple sites. This is very expensive and requires multiple visits to the hospital. Efudex Cream applied for 1 to 3 months will often work, but leaves an uncomfortable raw area during that time. Aldara cream can also be used to treat Bowen’s, with a two to three month treatment period required.

The latest treatment approved by the FDA but not yet in common use, is photodynamic therapy (PDT). PDT is an alternative way to “burn off” SCC in situ using a drug that is absorbed only by cancer cells. A bright light is then applies causing the release of toxins and destruction of the tumor.

If you have had an SCC in situ, you have a higher risk of other skin cancers. For this reason, you will need a regular skin exam by a dermatologist. Untreated, SCC in situ grows larger over time and may spread out to be several inches. 5% of SCC in situ will eventually develop into invasive squamous cell carcinoma if not treated.

The dermatologist based on his experience, expertise and analysis of your personal situation is the one best equipped to decide your personal treatment plan.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose


Ailmemts & Remedies

Woman Breast Pain

click & seeBreast pain can range from mild tenderness to a dull ache to a stabbing sensation in the breasts (milk-producing glands composed of fat and other tissue). According to the U.S. Department of Health and Human Services  Office on Women’s Health, approximately 50 percent of all women experience breast pain at some point in their lives.

In most cases, breast pain is caused by hormonal changes, such as those associated with the onset of puberty, menstruation, menopause, pregnancy and breastfeeding. In addition, certain medications, such as antidepressants, cardiovascular agents or oral contraceptives (birth control pills), can cause breast pain. However, women should notify their physician immediately if they experience breast pain that is persistent, more intense than usual or recurrent, especially if it is exhibited in only one breast… & see

Diagnosis of breast pain typically begins with a complete medical history and physical examination. Treatment for breast pain is directly related to the cause of the pain. For less serious causes of breast pain, treatment may be as simple as wearing a support bra or taking a pain reliever. For more severe cases of breast pain, there are medications that can relieve the discomfort. For women who are pregnant or breastfeeding, all drugs should be approved by a physician prior to use to avoid possible harm to the baby.
About breast pain
Breasts are milk-producing glands that are made up of fat and other tissue, including nerves, blood vessels and milk ducts (small tube-like paths). Breast pain can occur in a variety of forms – from a slight tenderness to a dull ache to a stabbing pain. Approximately half of all women experience breast pain at some point in their lives, according to the U.S. Department of Health and Human Services  Office on Women’s Health.

The medical terms for breast pain include mastalgia, mastodynia and mammalgia. It is usually caused by normal hormonal changes in a woman’s body, such as those associated with menstruation. Because of its strong association with hormones, breast pain or tenderness is more common in premenopausal women than in postmenopausal women. Some experts believe that stress can be another factor that affects the development and severity of breast pain. Other conditions that commonly cause breast pain include:

Fibrocystic breast changes
Breast cysts (fluid-filled sacs inside the breast)
Breast infection (mastitis)
Injury or trauma to the breast
Hormone replacement therapy (HRT)
Water retention (common during menstruation)
Surgery to the breast (e.g., breast implants)

Other, less common conditions that can cause breast pain include:

Poorly fitting bra or uncomfortable clothing
Medications, such as antidepressants, cardiovascular agents or oral contraceptives
Excessive caffeine consumption
Breast cancer
Nipple piercing that becomes infected
Mondor’s disease (a blood clot in the breast)
Liver damage from alcoholism
Arthritis or a pinched nerve in the neck area
Inflammation of a rib joint
Muscle pulls or strains