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Sleepless Night Can Trigger Disorders

Just one sleepless night can trigger the key cellular pathway that produces tissue-damaging inflammation, a new study has found.

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During the study, the researchers measured the levels of nuclear factor (NF)-?B, a transcription factor that serves a vital role in the body’s inflammatory signalling, in adults.

These measurements were repeatedly assessed, including in the morning after baseline (or normal) sleep, after partial sleep deprivation (where the volunteers were awake from 11 pm to 3:00 am), and after recovery sleep.

The assessment showed that in the morning after sleep loss, activation of NF-?B signalling was significantly greater than after baseline or recovery sleep, although they found this increase in inflammatory response in only the female subjects.

The researchers said that the new findings suggest a good night’s sleep can ease the risk of both heart disease and autoimmune disorders such as rheumatoid arthritis.

“The closer that we look at sleep, the more that we learn about the benefits of sleeping. In this case, Irwin and colleagues provide evidence that sleep deprivation is associated with enhancement of pro-inflammatory processes in the body,” said John H. Krystal, M.D., Editor of Biological Psychiatry and affiliated with both Yale University School of Medicine and the VA Connecticut Healthcare System.

“Our findings suggest even modest sleep loss may play a role in common disorders that affect sweeping segments of the population.” In other words, sleep is vitally important to maintaining a healthy body,” said Dr. Irwin, lead author and director of the Cousins Center for Psychoneuroimmunology at the Semel Institute.

“These findings provide a potential mechanistic avenue through which addressing sleep disturbance might improve health,” Krystal added.

A report appears in the September 15th issue of Biological Psychiatry.

Sources: The Times Of India

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Start Good New Habits

4 smart ways to simplify the family schedule to make room for healthy habits……..CLICK & SEE

How is it possible to eat dinner together and exercise more when both parents work and kids are overscheduled? It can be done, says William Doherty, co-author of Putting Family First

  • Schedule it. Make time for meals together just like you do for soccer practice or dentist appointments. Plan meals in advance, shop for groceries on weekends and freeze what you can.
  • Make it fun. Benefits from a family meal don’t happen just by sitting and eating together; it’s what you do with that time. First, turn off the TV and talk to one another. But avoid stressful subjects like report cards or work, or power struggles over food. Keep conversation light.
  • Go out and play. Remember that swing set in the backyard, the basketball hoop at the end of the driveway, the bikes in the garage? Even 15 minutes of fun together burns calories, reduces stress and promotes family bonding.
  • Take a break. Limit passive computer and TV time. Get up every 20 minutes and do some stretches, tackle a household chore or go out for a walk. It clears your mind and helps burn off lunch!

From:Reader’s Digest

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