Tag: Coronary artery disease

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Cholesterol Levels in Women

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What are HDL and LDL?
HDL and LDL are two different kinds of cholesterol that are measured as an index of a patient’s risk for cardiovascular disease. HDL stands for high-density lipoprotein and LDL stands for low-density lipoprotein. Total cholesterol measures the combination of HDL and LDL, along with several other factors. The levels of “fats” in the blood-total cholesterol, HDL (a subset called “good cholesterol”) and LDL (“bad cholesterol”) and triglycerides have been used for years to predict the risk of heart disease in men. Higher cholesterol, LDL, triglycerides, and/or low HDL all are associated with increased risk of heart diseases in men.

What do the numbers mean?
Many studies found that women with higher total cholesterol levels also had higher rates of a form of heart disease called coronary artery disease. That is where the arteries to the heart become clogged. This leads to heart attacks. For cholesterol, levels of about 200 or less are generally not associated with much increased heart disease. Women with total cholesterol levels of 265 or more have been found to have this disease two or three times as often as women with levels of about 200. Even mildly elevated levels, of about 235, had about 70% higher rates, than normal.

Men in the same situation are put on a diet and drugs to lower their cholesterol. The goal was to increase HDL, and lower LDL and total cholesterol. Little was done to lower elevated triglyceride levels. The men’s rates of disease dropped. A closer look at the problem in women found something different. Low HDL (“good cholesterol”) levels were the strongest predictor of heart disease in women. These are generally levels less than 50 (mg/dL). Low HDL and high cholesterol go hand in hand for many, which led to the confusion about what was important. Women with total cholesterol levels as low as 200 who also had low HDL levels still had high risks of heart disease. In fact, the best predictor for women, according to one study, was the ratio of cholesterol to HDL. If a woman’s total cholesterol is about 4 times or so of her HDL level, her risk of heart disease skyrockets to up to five times that of her normal counterpart. If her triglycerides are high, her risk goes up, too. Again, that happens even if she has a low total cholesterol level.

Unlike men, a high LDL (“bad cholesterol”) level is not as strong a predictor of future trouble, although there is still considerable debate on this. Some experts believe LDL is not to be worried about for most women, except for particular sub-groups of women who are affected. As one might expect, until we clarify the importance of LDL for women and factor in the additional significance HDL has for women, the HDL/LDL ratio’s significance is muddied.

The Bottom Line
Total cholesterol in and of itself does not matter so much. Look at the other factors and ratios: especially HDL, triglycerides, and the cholesterol to HDL ratio. The significance of LDL and ratios with it are uncertain. Most of all, keep checking for new research. This area is rapidly changing for women.

Source:www.estronaut.com

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Angina

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Definition:Ā  Angina pain develops when the muscles of the heart are not getting enough oxygen. This is usually caused by narrowing or blockages of the coronary arteries which deliver oxygen-rich blood to the heart muscle (known as coronary artery disease). So angina is a sign of heart disease……….click & see

If the blockage of a coronary artery progresses and becomes complete, then the blood supply to part of the muscles of the heart is lost, causing a heart attack. Angina is a warning sign that the heart is at risk of a heart attack, and should be taken very seriously. One patient in every ten will go on to have a heart attack within a year of diagnosis of angina.

When your heart isn’t getting enough blood and oxygen, the crushing, squeezing pain of angina is typically the result. Usually the pain begins below the breastbone and radiates to the shoulder, arm, or jaw, increasing in intensity until it reaches a plateau and then diminishes. The attack can last up to 15 minutes.

Angina may be an occasional problem or may rapidly increase in severity and duration until a heart attack occurs.

Although conventional medications for angina may help relieve the intense chest pain of this heart disorder, they do very little to halt the physiological mechanisms behind it. Vitamins, minerals, and natural remedies may actually improve the condition — or at least keep it from.

Symptoms:…….

Symptoms include:

*Crushing or squeezing chest pain.
*Weakness.
*Sweating.
*Shortness of breath.
*Palpitations.
*Nausea.
*Light-headedness.

When to Call Your Doctor
If you have any of the above symptoms for the first time.
If there is any change in the normal pattern of your angina attacks — for example, if they increase in frequency, intensity, or duration, or if they are brought on by new activities.
If an angina attack lasts more than 15 minutes, which may be a heart attack — call for an ambulance immediately.
Reminder: If you have a medical condition, talk to your doctor before taking supplements.

Causes and risk factors:
Angina is common ā€“ about eight per cent of men and three per cent of women aged between 55 and 64 have experienced it, and it becomes more common with age.

Itā€™s most commonly caused by narrowing of the arteries which carry oxygen to the heart muscle by a process called atherosclerosis (sometimes known as hardening of the arteries). This is a common condition where fatty deposits or plaques build up in the coronary arteries. Symptoms donā€™t usually develop until there is at least a 50 per cent blockage of the artery.

Most people in the developed world will have some atherosclerosis by the time they reach mid-life (and often much earlier), but some conditions can make it worse including:

ā€¢High cholesterol levels in the blood (especially if there is an inherited tendency to high cholesterol or a strong family history of heart disease).
ā€¢Cigarette smoking.
ā€¢Diabetes mellitus.
ā€¢High blood pressure.
Other conditions can also interfere with the blood supply to the heart muscle and lead to angina. These include:

ā€¢Abnormal heart rhythms (for example when the heart beats so fast that it isnā€™t pumping blood efficiently around the body).
ā€¢Heart valve disease.
ā€¢Inherited structural abnormalities of the coronary arteries.
ā€¢Severe anaemia (where the blood count is so low that it cannot carry much oxygen to the tissues).
Other important risk factors for angina include obesity, and raised levels of chemical in the blood called homocysteine, or other chemicals involved with clotting.

In another condition, known as Prinzmetalā€™s angina or coronary artery spasm, the coronary arteries arenā€™t permanently blocked but intermittently narrowed by spasm. This often develops in the early hours of the morning and may last up to 30 minutes. Those affected may also complain of palpitations and abnormal heart rhythms, or have similar conditions linked to spasm of the arteries such as migraine or Raynaudā€™s phenomenon.

Events which put extra strain on the heart can make angina worse, such as:

ā€¢Fever.
ā€¢Infection and serious illness.
ā€¢Emotional stress.
ā€¢An overactive thyroid gland.
ā€¢Sudden extreme exertion.
But angina can come on at rest, even when a person is lying down in bed.

Diagnosis and modern treatment :
There are many problems which can be confused with angina, especially simply indigestion or gastro-oesophageal reflux. There may be no visible signs of angina so itā€™s important that tests are done to establish the diagnosis, to ensure the affected person gets the right treatment.

An electrocardiogram (ECG) is essential and may show typical changes but can be normal in angina. Blood tests can be done to check for causes such as anaemia and look for chemical enzymes (called Troponins) released from the heart if a heart attack has occurred. Other checks for cholesterol levels, blood fats, diabetes and thyroid disease may be done. In most areas of the UK these tests will be done at the local Rapid Access Chest Pain Clinic.

More complex tests such as an ECG during exercise, echocardiogram or other sophisticated x-ray tests may be recommended. However, NICE has recently produced guidelines which direct which tests should be done based on a statistical calculation of how likely to patient is to have angina. For example, invasive coronary angiography (where a tube is inserted into the coronary arteries and dye injected to produce x-rays pictures of the coronary arteries) is usually offered when there is a greater than 61 per cent chance of coronary artery disease.

Treatment of angina includes:

ā€¢Lifestyle advice to manage risk factors, such as weight loss, exercise, quitting smoking and a healthy diet.
ā€¢Medical treatment, including a drug called glyceryl trinitrate or GTN which can be taken repeatedly as a tablet put under the tongue or as a spray, and medical advice on what to do if pain persists (ie. if there is a risk of a heart attack).
ā€¢Assessment and treatment for coronary artery disease, including a variety of drug treatments to help open the arteries or treatments such as aspirin and a statin type drug which help to reduce the risk of a heart attack. More invasive treatments to open up the coronary arteries may be recommended especially when there is severe blockage. These are known as coronary revascularisation. The main two types are either coronary artery bypass grafting, or percutaneous transluminal angioplasty.

How Supplements Can Help
The supplements listed in the chart can all be used together or alone. They can also complement your prescription angina medications; never stop your heart medication without first consulting your doctor, however.
The antioxidant effect of vitamins C and E can help prevent cell damage: Vitamin C aids in the repair of the arteries injured by plaque, and vitamin E blocks the oxidation of LDL (“bad”) cholesterol, the initial step in the formation of plaque. In addition, some people with heart disease have low levels of vitamin E as well as the mineral magnesium, which may inhibit spasms of the coronary arteries.

Amino acids can benefit the heart in several ways. Arginine plays a role in forming nitric oxide, which relaxes artery walls. One study found that taking this amino acid three times a day increased the amount of time individuals with angina could exercise at moderate intensity without having to stop because of chest pain. Carnitine, an amino acid-like substance, allows heart muscle cells to use energy more efficiently, and another amino acid, taurine, may temper heart rhythm abnormalities.

Like carnitine, the nutritional supplement coenzyme Q10 enhances the heart muscle, reducing its workload, and the herb hawthorn improves blood flow to the heart. Essential fatty acids may be effective in lowering triglyceride levels and keeping arteries flexible.

What Else You Can Do
Eat a low-fat, fiber-rich diet; use canola or olive oil instead of butter.
Don’t smoke and avoid smoky places.
Learn to relax. Meditation, t’ai chi, and yoga may reduce angina attacks.
Join a support group. Determine what brought you to this point in your life and what you can do to begin reversing the disease.

Supplement Recommendations
Vitamin C
Vitamin E
Magnesium
Arginine
Carnitine
Taurine
Coenzyme Q10
Hawthorn
Essential Fatty Acids

Vitamin C
Dosage: 1,000 mg 3 times a day.
Comments: Reduce dose if diarrhea develops.

Vitamin E
Dosage: 400 IU twice a day.
Comments: Check with your doctor if taking anticoagulant drugs.

Magnesium
Dosage: 200 mg twice a day.
Comments: Do not take if you have kidney disease.

Arginine
Dosage: 500 mg L-arginine 3 times a day on an empty stomach.
Comments: If using longer than 1 month, add mixed amino acids.

Carnitine
Dosage: 500 mg L-carnitine 3 times a day on an empty stomach.
Comments: If using longer than 1 month, add mixed amino acids.

Taurine
Dosage: 500 mg L-taurine 3 times a day on an empty stomach.
Comments: If using longer than 1 month, add mixed amino acids.

Coenzyme Q10
Dosage: 100 mg twice a day.
Comments: For best absorption, take with food.

Hawthorn
Dosage: 100-150 mg 3 times a day.
Comments: Standardized to contain at least 1.8% vitexin.

Essential Fatty Acids
Dosage: 1 tbsp. flaxseed oil a day; 2,000 mg fish oils 3 times a day.
Comments: Take fish oils if you don’t eat fish at least twice a week.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Resource:

http://www.bbc.co.uk/health/physical_health/conditions/in_depth/heart/angina.shtml
http://www.gulfmd.com/cardiology/Facts_About_Angina.asp
http://indiahealthtour.com/treatments/health-check-screening/treadmill-test-india.html

Your Guide to Vitamins, Minerals, and Herbs

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Federal Panel to Review Use of Artery Device

PFIZER’S decision last weekend to abandon a promising cholesterol drug is but the latest recent setback as the health care industry continues its assault on cardiovascular disease, which has remained the leading cause of death and disability in Western societies since World War I………....click & see

Another reminder of the difficulties will come this week in Washington. Thursday will be the first of two days of hearings by a federal advisory panel that is expected to recommend stricter regulation on the use of drug-coated stents, the medical device industryĆ¢ā‚¬ā„¢s most popular tool for dealing with clogged heart arteries.

The panel will weigh evidence that the stents, which were developed to keep coronary arteries open after they have been cleared of plaque, can in some cases cause fatal blood clots months or even years after they have been put in patients.

Ć¢ā‚¬Å“From where we sit, there are more questions than answers,Ć¢ā‚¬Ā said Dr. Daniel G. Schultz, director of the Center for Devices and Radiological Health at the Food and Drug Administration, which is holding the hearings.

Wall Street is uneasy, too. The nation’s market leader in stents, Boston Scientific, whose stock was struggling under the weight of the company’s $27 billion takeover of Guidant in April, has experienced an additional 7 percent stock decline in the last three monthsĀ  largely on rising concern among doctors and consumers about the long-term clotting risks.

The nation will spend close to $258 billion treating cardiovascular diseases this year, according to the American Heart Association, including $50 billion on devices and drugs.

But drug and device companies face a shifting landscape in which the traditional image of the heart and circulatory system Ā  pipes and pumps where any clogging is a threat Ā  has been replaced by a far more complicated picture. It is now clear that the human circulatory system can adapt to some types of clogging, but that patients can be killed without warning by the rupture of Ć¢ā‚¬Å“vulnerable plaqueĆ¢ā‚¬Ā: fatty deposits containing a stew of cells that can cause rapid formation of a clot.

So far, though, there is no sure way to locate which plaques are about to rupture. Nor is there a proven drug or device for preventing their formation, dissolving them or sealing them off.

Ć¢ā‚¬Å“Technology is pushing against the limits of our knowledge, and we are finding that to a certain extent, things are more complicated than we thought,Ā Ā  said Dr. Barry T. Katzen, director of the Baptist Cardiac and Vascular Institute at Baptist Hospital of Miami.

There are numerous forms of cardiovascular disease, which causes or contributes to the death of 2,500 Americans every day, according to the American Heart Association. While heart attack may be the most obvious dire outcome, symptoms as diverse as swelling of the feet, sexual dysfunction, stroke, kidney failure and chest pains are all common.

The death rate has been falling since the 1960s, a trend driven by the decline of smoking and more attention to healthier diets and lifestyles. But medical technology like heart pacemakers and defibrillators; blood-thinning and anti-clotting.
drugs; and, more recently, the cholesterol-fighting statin drugs have all helped, too.

Pfizer was chasing a potential blockbuster vision of reversing the progression of heart disease. Its drug torcetrapib stimulates production of a fat-grabbing protein Ā  high-density lipoprotein, or HDL, the so-called good cholesterol. High levels of HDL can reverse plaque accumulation.

In theory, drug companies that are already working on closely related HDL stimulators may achieve torcetrapib’s benefits without its dangerous side effect of raising blood pressure. But Dr. Steven E. Nissen, chairman of cardiovascular medicine at the Cleveland Clinic, who was the lead investigator on an early clinical trial that highlighted the promise of torcetrapib, said researchers might now have difficulty enrolling patients in trials of related drugs.Ā Ā  It might kill the class, Ā he said.

Stents, meanwhile, are frequently used to relieve the disabling discomfort of angina rather than treat acute heart disease. They were introduced in the 1990s as an enhancement to angioplasty, a procedure in which a tiny balloon is inflated inside a blockage in a blood vessel to create a broader channel for blood flow. Bare-metal stents halved the frequency with which coronary arteries quickly clogged up again at the angioplasty site to about 20 percent.

Drug-coated stents, introduced in the United States in 2003, cut the reblockage frequency in half again and quickly grabbed close to 90 percent of the market because they saved patients the costs and risks of repeat procedures. Boston ScientificĆ¢ā‚¬ā„¢s Taxus and Johnson & Johnson Cypher are the only drug-coated devices currently approved for sale, although Medtronic recently asked the F.D.A. to approve its Endeavor stent, and several other potential competitors are also developing products.

But now stent sales are falling in the United States and doctors report numerous calls from patients wondering whether the drug-coated devices are ticking time bombs. The risk may be slight, but it adds up to tens of thousands of heart attacks annually, because 600,000 Americans now receive coronary stents each year. And research suggests that such heart attacks kill as many as half of the patients who suffer them.

So far, the added risks of late clotting appear to balance the added risks of repeat procedures for bare-metal stents. That leaves unsettled the question of which device Ć¢ā‚¬ā€ the drug-coated or the bare-metal stent Ć¢ā‚¬ā€ might be safer in the long run.

One contentious issue the F.D.A. panel plans to discuss is the risk, benefit and cost of keeping patients indefinitely on a daily diet of aspirin and the anticlotting drug Plavix, to reduce the late clotting risk. Wall Street will also be watching closely to find out whether the panelists urge the F.D.A. to discourage the widespread Ć¢ā‚¬Å“off-labelĆ¢ā‚¬Ā use of drug-coated devices in groups of patients who are in poorer health than those studied in the clinical trials.

One suggestion has been that the F.D.A. may require longer-term safety data for new stents. Because many of the new designs have features and early data suggesting they may be safer than Taxus or Cypher, however, some experts believe the F.D.A. will end up requiring more rigorous follow-up studies, rather than delay their entry into the market.

The new designs point to a persistent challenge for medical device regulators. Will changing technology render obsolete much of the safety data doctors are clamoring for about todayĆ¢ā‚¬ā„¢s devices before it can be compiled?

Source:New York Times

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Little chocolate a day keeps heart attacks at bay

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They were so addicted, they just could not give up their favourite daily snackĀ  not even in the interest of science…..click & see

But chocolate lovers who flunked out of a Johns Hopkins University study on aspirin and heart disease helped researchers stumble on an explanation of why a little chocolate a day can cut the risk of heart attack.

It turns out chocolate, like aspirin, affects the platelets that cause blood to clot, Diane Becker of the Johns Hopkins University’s School of Medicine and her colleagues discovered.

“What these chocolate offenders taught us is that the chemical in cocoa beans has a biochemical effect similar to aspirin in reducing platelet clumping, which can be fatal if a clot forms and blocks a blood vessel, causing a heart attack,”Becker said.

The 139 so-called chocolate offenders took part in a larger study of 1,200 people with a family history of heart disease.

The study looked at the effects of aspirin on blood platelets. Before they got the aspirin, the volunteers were asked to stay on a strict regimen of exercise, refrain from smoking and avoid caffeinated drinks, wine, grapefruit juice and chocolate.

Source:The Times Of India

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Coronary Heart Disease

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The term coronary heart disease covers a group of clinical syndromes arising particularly from failure of the coronary arteries to supply sufficient blood to the heart. They include angina pectoris, coronary thrombosis or heart attack, and sudden death without infarction. click & see

Symptoms:
1.Shortness of breath :A common symptom of heart disease is shortness of breath, which is caused by the blood being deprived of the proper amount of oxygen.

2. Chest pain or pain down either arm:Another common symptom is chest pain or pain down either arm.

3. Palpitations, fatigue, fainting, emotional instability, cold hands and feet:Other symptoms are palpitations, fainting, emotional instability, cold hands and feet, frequent perspiration, and fatigue.

Causes :Family history;wrong eating habit;faulty style of living;obesity;smoking;elevated blood levels of cholesterol, triglycerides, and other fatty substances;elevated blood pressure, elevated blood uric acid levels (mainly caused by high protein diet);certain metabolic disorders, notably diabetes:lack of physical exercise….Each or a combination of these risk factors can contribute to heart disease. Most of them are of dietary origin. Constant worry and tension stimulate the adrenal glands to produce more adrenaline and cortisone. This also contributes to constricted arteries, high blood pressure and increased work for the heart.

Let me jot down some preventive very common home medicines which might give some relief to Coronary Heart Patients:-

Firstly, patient should always pay attention to other laws of nature for health building such as taking moderate exercise, getting proper rest and sleep, and adopting a positive mental attitude and try to create happiness within.

Yoga is most effective in this type disease.

Some Home Remedy:
Coronary Heart Disease treatment using Grapes

Fresh fruits in general are beneficial in the treatment of heart disease. They tone up the heart. Grapes are especially effective in heart pain and palpitation of the heart, and the disease can be rapidly controlled if the patient adopts an exclusive diet of grapes for a few days. Grape juice is particularly valuable when one is actually suffering from a heart attack.

Coronary Heart Disease treatment using Apple

Apples have heart-stimulating properties. Patients suffering from a weak heart will benefit greatly by making liberal use of this fruit and apple jam.

Coronary Heart Disease treatment using Indian Gooseberry

Indian gooseberry is considered an effective home remedy for heart disease. It tones up the functions of all the organs of the body, and builds up health by destroying the heterogeneous elements and renewing lost energy. When the fruit is in season, one medium-sized Indian gooseberry can be taken with a little salt daily; when not in season, dry pieces can be chewed .

Coronary Heart Disease treatment using Onion

Onions have been found valuable in heart disease. They are useful in normalising the percentage of blood cholesterol by oxidising excess cholesterol. One teaspoon of raw onion juice first thing in the morning is beneficial in such cases.

Coronary Heart Disease treatment using Honey

Honey has got marvellous properties to prevent all sorts of heart disease. It tones up the heart and improves the circulation. It is also effective in cardiac pain and palpitation of the heart. One tablespoon daily after food is sufficient to prevent all sorts of heart troubles.

Coronary Heart Disease treatment using Asparagus

Asparagus is an excellent food for strengthening the heart.. A good medicine for a weak or an enlarged heart is prepared by mixing the freshly extracted juice of this vegetable with honey, in the ratio of 2:1. A teaspoon of this medicine should be taken three times daily. Patients with heart disease will also benefit by steam cooking this vegetable.

Coronary Heart Disease treatment using Alfalfa

The herb alfalfa in the form of juice has been found very helpful in most troubles related to the arteries and heart diseases.Only the leaves of the plant are used for this purpose, when they can be obtained fresh. The juice of fresh alfalfa is, however, too strong and potent to be taken by itself. It is best taken with carrot juice in equal quantities of 125ml each, twice daily.In this combination, the individual benefits of each juice are intensified.

Coronary Heart Disease treatment using Safflower

Safflower oil has proved beneficial in lowering blood cholestrol. Hence it can be used liberally with persons suffering from cardiovascular disorders. An emulsion with the trade name Saffloxin-Cipla is used routinely during myocardial infarction, cardiac ischaemia, and hypertension.

Coronary Heart Disease treatment using Vitamin E

Patients with heart disease should increase their intake of foods rich in vitamin E, as this vitamin is said to promote heart function by improving oxygenation of the cells. It also improves the circulation and muscle strength. Many wholemeal products and green vegetables, particularly outer leaves of cabbage, are good sources of vitamin E.

Coronary Heart Disease treatment using Vitamin C

Vitamin C is also essential as it protects against spontaneous breaches in capillary walls which can lead to heart attacks. It also guards against high blood cholesterol. The stress of anger, fear, disappointment., and similar emotions can raise blood fat and cholesterol levels immediately but this reaction to stress can do little harm if the diet is adequate in vitamin C and pantothenic acid. One of the richest sources of vitamin C is citrus fruits.

Coronary Heart Disease diet

Diet should be lacto-vegetarian, low on sodium and calories

The fundamental conditioning factor in all heart diseases is the diet, which should be lacto-vegetarian, and low on sodium and calories. It should consist of high quality, natural organic foods, with emphasis on wholegrains, seeds, fresh fruits, and vegetables

Try to avoid food like white flour products, tea, coffee, tobacco, salt and sugar

Foods which should be eliminated from the diet include white flour products, sweets, chocolates, canned foods in syrup, soft drinks, squashes, tea, coffee, alcohol, and tobacco, and all solid fats of animal origin such as butter, cream and fatty meats. Salt and sugar should he reduced substantially.

DOCTORS SHOULD ALWAYS BE CONSULTED FOR ALL KINDS OF HEART DISEASES.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.

Partly extracted from:http://www.home-remedies-for-you.com/remedy/Coronary-Heart-Disease.html

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