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News on Health & Science

Do Arthritis Drugs Cause Cancer?

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The U.S. Food and Drug Administration (FDA) is investigating whether four drugs used to treat rheumatoid arthritis and other immune system diseases might increase the risk of cancer in children.

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The FDA has received reports of 30 cases of cancer among children and young adults treated with the drugs. The agency did not make clear how many children had taken the drugs.

The drugs involved are:

1. Enbrel, sold by Amgen and Wyeth
2. Remicade, sold by Johnson & Johnson and Schering-Plough
3. Humira, sold by Abbott Laboratories
4. Cimzia, sold by the Belgian company UCB

All of the drugs block a protein called tumor necrosis factor, and are therefore known as TNF-blockers. They are used to treat not only rheumatoid arthritis but also psoriasis, Crohn’s disease and other immune diseases.

Because the drugs block part of the immune system, it’s long been known that they might contribute to a higher risk of cancers and infections. The drugs’ labels contain warnings as such, including warning about a risk of lymphomas, which are cancers of immune system cells.

Among adults, meanwhile, one study found that those given Humira or Remicade to treat rheumatoid arthritis had 2.4 times the cancer rate of those in control groups.

Sources: New York Times June 5, 2008

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Ailmemts & Remedies

Inflammatory Bowel Disease

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This chronic condition, which actually encompasses several related disorders, is marked by an often painful inflammation of the intestines. Symptoms may be eased with dietary changes, vitamin supplements, and soothing herbs….CLICK & SEE

Symptoms

Early symptoms may include constipation and the frequent urge to defecate, with passage of only small amounts of blood or mucus.
Later symptoms include chronic diarrhea with rectal bleeding, abdominal pain, low-grade fever, general malaise, arthritis, mouth sores, blurred vision, painful joints, poor appetite, low energy, and weight loss. After a decade, there’s increased risk for colorectal cancer.
Symptoms may come and go. A severe attack can cause nausea, vomiting, dehydration, heavy sweating, loss of appetite, high fever, and heart palpitations.

When to Call Your Doctor
If you have black or bloody stools, or painful, mucus-filled diarrhea.
If symptoms suddenly worsen.
If you have a swollen abdomen or severe pain (especially on the lower-right side) — it may be a sign of appendicitis.
If severe abdominal pain accompanies fever over 101 F.
Reminder: If you have a medical condition, talk to your doctor before taking supplements.

What It Is
Inflammatory bowel disease (IBD) is a general term for several related disorders (including Crohn’s disease and ulcerative colitis) that often first strike people in their 20s or 30s. Typically, all or part of the digestive tract becomes chronically inflamed and develops small erosions, or ulcers. Bouts of inflammation are followed by periods of remission lasting weeks or years.

What Causes It
Experts are not entirely sure why people develop IBD, although heredity plays a part. More than a third of IBD sufferers know of a family member afflicted with the disease, and it’s four times more common in Caucasian and Jewish families. The disease may be triggered by a bacterium or a virus, or by a malfunctioning immune system. Factors such as stress and anxiety, or sensitivity to certain foods, can all contribute to flare-ups.

How Supplements Can Help
IBD usually causes a decreased ability to absorb nutrients from food, so a daily high-potency multivitamin is essential. Additional supplements, taken together, may also be beneficial, especially during flare-ups.

What Else You Can Do
Determine if certain foods trigger flare-ups and then eliminate them.
Apply a hot pack or hot water bottle to the abdomen to prevent cramps.
Minimize stress with yoga, meditation, and regular exercise.
In addition to chamomile, herbal teas made from flaxseed, slippery elm, or marshmallow aid digestion and soothe the intestines. To make the tea, use 1 or 2 teaspoons of herb per cup of hot water; steep for 10 to 15 minutes, then strain.
Ask your doctor about nicotine patches, which may help put active cases of ulcerative colitis into remission, according to a small Mayo Clinic study. Of 31 patients who used high-dose nicotine skin patches for four weeks, 12 were significantly better; only 3 of 33 who wore placebo patches showed some improvement. But side effects were common, including dizziness, nausea, and skin rashes. Additional research is needed.

Supplement Recommendations

Vitamin B Complex
PABA
Licorice (DGL)
Vitamin E
Vitamin A
Essential Fatty Acids
Acidophilus
Zinc/Copper
Chamomile

Vitamin B Complex
Dosage: 1 pill twice a day for flare-ups; then reduce to 1 pill each morning for maintenance; take with food.
Comments: Look for a B-100 complex with 100 mcg vitamin B12 and biotin; 400 mcg folic acid; and 100 mg all other B vitamins.

PABA
Dosage: 1,000 mg 3 times a day for flare-ups.
Comments: Take 1,000 mg twice a day for maintenance.

Licorice (DGL)
Dosage: Chew 2 wafers (380 mg) 3 times a day, between meals.
Comments: For flare-ups; use deglycyrrhizinated (DGL) form only.

Vitamin E
Dosage: 400 IU twice a day for flare-ups or maintenance.
Comments: Check with your doctor if taking anticoagulant drugs.

Vitamin A
Dosage: 50,000 IU a day for flare-ups; reduce to 10,000 IU a day for maintenance.
Comments: Take only 5,000 IU a day if you may become pregnant.

Essential Fatty Acids
Dosage: 1 tbsp. (14 grams) flaxseed oil or 5,000 mg fish oils a day.
Comments: Use enteric-coated form of fish oils as maintenance.

Acidophilus
Dosage: Take 1 pill twice a day between meals.
Comments: Get 1-2 billion live (viable) organisms per pill.

Zinc/Copper
Dosage: 30 mg zinc and 2 mg copper a day.
Comments: Add copper only when using zinc longer than 1 month.

Chamomile
Dosage: 1 cup of tea up to 3 times a day.
Comments: Use 2 tsp. dried herb per cup of hot water.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Source:Your Guide to Vitamins, Minerals, and Herbs(Reader’s Digest)

Categories
Herbs & Plants

Cat’s Claw (Uncaria Tomentosa)

Botanical Name :Uncaria tomentosa

Family: Rubiaceae

Kingdom: Plantae

Division: Magnoliophyta

Class:
Magnoliopsida

Order: Gentianales

Genus: Uncaria

Species: U. tomentosa

Synonyms: Uncaria surinamensis, Nauclea aculeata, N. tomentosa, Ourouparia tomentosa
Common Names: cat’s claw, uña de gato, paraguayo, garabato, garbato casha, samento, toroñ, tambor huasca, uña huasca, uña de gavilan, hawk’s claw, saventaro

Plant parts used: bark, root, leaves

Uncaria tomentosa (popularly known in English as Cat’s Claw, in Spanish as Uña de Gato or as indian name Vilcacora) is a woody vine found in the tropical jungles of South and Central America, which derives its name from its claw-shaped thorns. It is used as an alternative medicine in the treatment of a variety of ailments.

Habitat:Cat’s claw is indigenous to the Amazon rainforest, with its habitat being restricted primarily to the tropical areas of South and Central America.
Description:Uncaria tomentosa is a liana deriving its name from hook-like thorns that resemble the claws of a cat. U. tomentosa can grow up to 30m tall, climbing by means of these thorns. The leaves are elliptic with a smooth edge, and grow in opposite whorls of two.There are two species of Cat’s Claw, Uncaria tomentosa and Uncaria guianensis, each having different properites and uses. The two are frequently confused but U. tomentosa is the more heavily researched for medicinal use   and immune modulation, while U. guianensis may be more useful for osteoarthritis. U. tomentosa is further divided into two chemotypes with different properties and active compounds, a fact ignored by most manufacturers that can have significant implications on both its use as an alternative medicine and in clinical trials to prove or disprove its efficacy.

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An Astounding “New” Herb from the Peruvian Rainforests.
by Phillip Steinberg, certified nutritional consultant
For hundreds of years a rather remarkable plant has been revered and used by the indian natives of the Peruvian Amazon to “cure” cancer, arthritis, gastritis, ulcers, and female hormonal imbalances.

Researchers have determined that this plant, uncaria tomentosa, more commonly called “cat’s claw,” contains a wealth of beneficial phytochemical compounds: alkaloids, proanthocyanidins, polyphenols, triterpines, and plant sterols. Because of these compounds, cat’s claw is a powerful cellular reconstitutor, displaying significant antibacterial, antiviral, antifungal, antitumor, anti-inflammatory, and anti-oxidant properties.

According to the available research and experience of doctors working in Peru, Germany, Austria, and the United States, cat’s claw may be helpful in the treatment of: cancer; arthritis; bursitis; rheumatism; all forms of herpes; allergies; asthma; systemic candidiasis; acne; diabetes; lupus; prostatitis; chronic fatigue syndrome; PMS; irregularities of the female cycle; environmental toxin poisoning; organic depression; and those infected with the HIV virus. Evidence also suggests that cat’s claw may be effective in the treatment of numerous stomach and bowel disorders including.

The most exciting research has been the work of Dr. Klaus Keplinger, an Austrian scientist who has obtained two United States patents for isolating the alkaloids responsible for enhancing phagocytosis. This has resulted in the development of a pharmaceutical which is now being used in Austria and Germany to combat the progression of cancer and AIDS. Unfortunately, the pharmaceutical is not available in the US, but the herb is available both in tea and in capsule form.

Traditionally in Peru, a decoction is made by boiling the bark and/or root for about an hour and then drinking four or more cups of tea per day. When using capsules, three to six grams per day is considered therapeutic. However, as much as 20 grams per day might be used for several weeks at a time to treat very advanced stages of pathology.

Dr. Satya Ambrose, ND, the co-founder of the Oregon College of Oriental Medicine, has been using the bark in capsule form with some of her patients for the past several months. She said that excellent results with Crohn’s disease, ulcers, asthma, and fibromyalgia. It is observed that successes with lupus, lung cancer, prostatitis, and one patient who was able to reverse and overcome Kaposi’s sarcoma, a rare form of skin cancer associated with AIDS.

It is also found that the herb to be effective at knocking out the flu, clearing up sinus, ear, and upper respiratory infections, canker sores, lower back pain associated with arthritis, and eliminating the tired, sore muscles associated with heavy physical work and exercise. I was even able to clear up a case of athlete’s foot by putting the powdered bark between the infected toes. It can cure conjunctivitis by putting drops of the tea in eyes several times over the course of two days.

Because of research and first hand experience in using this wondrous and remarkable herb, it is believed that cat’s claw is an effective natural remedy for many of today’s serious health problems.

We can learn more about Cat’s Claw from link 1 , link2

Biochemistry
Principal active biochemicals are six oxindole alkaloids and a number of others: ajmalicine, akuammigine, campesterol, catechin, chlorogenic acid, cinchonain, corynantheine, corynoxeine, daucosterol, epicatechin, harman, hirsuteine, hirsutine, iso-pteropodine, loganic acid, lyaloside, mitraphylline, oleanolic acid, palmitoleic acid, procyanidins, pteropodine quinovic acid glycosides, rhynchophylline, rutin, sitosterols, speciophylline, stigmasterol, strictosidines, uncarine A-F, and vaccenic.

The oxindole alkaloids significantly enhance the ability of white blood cells to attack, engulf, and digest harmful microbes or foreign bodies.

Documented Properties& Actions: Analgesic, anti-inflammatory, antimutagenic, antioxidant, antiproliferative, antitumorous, antiviral, cytoprotective, cytostatic, cytotoxic, depurative, diuretic, hypotensive, immunostimulant, immunomodulatory

Medicinal uses
The parts used medicinally include the inner bark and root, taken in the form of capsules, tea and extract.

U. tomentosa is used in nootropic drugs, as well as in treatment of cancer and HIV infection. It contains several alkaloids that are responsible for its overall medical effects, as well as tannins and various phytochemicals. The chemotype of the plant determines the dominant type of alkaloid it produces, and thus its properties in vivo. One chemotype has roots which produce mostly the pentacyclic alkaloids that are responsible for the immune-strengthening effects desired by most consumers. The second chemotype produces tetracyclic oxindole alkaloids known as rhynchophylline and isorhynchophylline which counteract the immune-strengthening actions of the pentacyclic alkaloids, reduces the speed and force of the heart’s contraction, and in high doses produce ataxia, lack of coordination and sedative effects. Since U. tomentosa comes in at least these two different chemotypes, without chemical testing it is impossible to know which chemical compounds will predominate in a plant collected randomly from a natural setting.

Some ingredients appear to act as anti-inflammatory, antioxidant and anticancer agents.[6] As an herbal treatment, Cat’s Claw is used to treat intestinal ailments such as Crohn’s disease, gastric ulcers and tumors, parasites, colitis, gastritis, diverticulitis and leaky bowel syndrome, while manufacturers claim that U. tomentosa can also be used in the treatment of AIDS in combination with AZT, the treatment and prevention of arthritis and rheumatism, diabetes, PMS, chronic fatigue syndrome, prostate conditions, immune modulation, Lyme disease and systemic lupus erythematosus. A 2005 review of the scholarly literature on Cat’s Claw indicates there is supporting evidence toward its use in treating cancer, inflammation, viral infection and vascular conditions, and for its use as an immunostimulant, antioxidant, antibacterial and CNS-related agent.

In herbal medicine today, cat’s claw is employed around the world for many different conditions including immune disorders, gastritis, ulcers, cancer, arthritis, rheumatism, rheumatic disorders, neuralgias, chronic inflammation of all kinds, and such viral diseases as herpes zoster (shingles). Dr. Brent Davis, D.C., refers to cat’s claw as the “opener of the way” for its ability to cleanse the entire intestinal tract and its effectiveness in treating stomach and bowel disorders (such as Crohn’s disease, leaky bowel syndrome, ulcers, gastritis, diverticulitis, and other inflammatory conditions of the bowel, stomach, and intestines). .

Indigenous use
The indigenous peoples of South and Central America have used U. tomentosa for medicinal purposes for two thousand years or more. Researchers have investigated the use of the plant by the Asháninka tribe of Peru, who use the plant as a general health tonic, contraceptive, anti-inflammatory agent for the gastrointestinal tract, and as a treatment for diarrhea, rheumatic disorders, acne, diabetes, cancer and diseases of the urinary tract.

Allergies
Individuals allergic to plants in the Rubiaceae family and different species of Uncaria may be more likely to have allergic reactions to Cat’s Claw.Reactions can include itching, rash and allergic inflammation of the kidneys. In one documented case, kidney failure occurred in a patient with Lupus erythematosus but it is not known if this was due to an allergic reaction or another cause.

There are other plants which are known as cat’s claw (or uña de gato) in Mexico and Latin America; however, they are entirely different plants, belonging to neither the Uncaria genus, nor to the Rubiaceae family. Some of the Mexican uña de gato varieties are known to have toxic properties.

Uña de Gato,”cat’s claw”, is a thorny liana vine reputed to be a remarkably powerful immune system booster and effective in treating a wide array of maladies including cancer, systemic candidiasis, genital herpes, and AIDS (SIDA).

Uña de Gato also has anti-tumor, anti-inflammatory, and anti-oxidant properties. It has proven useful in treating arthritis, bursitis, allergies and numerous bowel and intestinal disorders. Anecdotal evidence indicates effectiveness in relieving side effects of chemotherapy.

Wild populations of this woody vine are threatened in some areas by harvesters who dig out the root out rather than simply cutting the vine and allowing regrowth. This is a foolish practice since new growth occurs rapidly when Uña de Gato vine is cut. It grows prolifically under cultivation.

Uncaria tomentosa, reputedly the most effective of several uña de gato species, is endemic to the Peruvian Amazon and is gaining international attention for its documented curative qualities.

You may click to see:->an article  from Herb Library on Cat’s Claw

Disclaimer : The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplement, it is always advisable to consult with your own health care provider.

Resources:
http://en.wikipedia.org/wiki/Uncaria_tomentosa
http://www.biopark.org/peru/unadegato.html
www.chiroweb.com

http://www.herbnet.com/Herb%20Uses_C.htm

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