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Study Supports Cranberry Dose Levels for Urinary Health

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The effect of cranberry proanthocyanidins (PACs) is dependent on the dose. Higher doses are significantly more effective at maintaining urinary health.

A new study supports the theory that at least 36 milligrams of proanthocyanidins (PAC) are needed to reduce the adhesion of E. coli bacteria to urinary tract walls. A lower dose proved to be less effective.

However, according to NutraIngredients:

“On the other hand, a higher dose of 72 mg was even more efficient at protecting against bacterial adhesion in the urinary tract, according to findings published in the open-access journal BMC Infectious Diseases.”

Source: NutraIngredients June 1, 2010

Posted By Dr. Mercola | April 20 2011

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The 7 Germiest Public Places

It is possible for a person to touch about 30 things in one minute from daily and normal activities.

This heightens the chance of contracting and spreading germs to and from all these objects if in a public setting. But there are ways to avoid being infected by knowing the more obscure places germs hide other than door knobs, light switches, and bathroom surfaces. Here are 3 out of 7 listed by ABC News:

Restaurant menus…..
Studies from the Journal of Medical Virology reports germs like the cold and flu viruses can survive for up to 18 hours on a hard surface. When dining in a public place, be conscious to not let the menu touch your flatware and wash your hands after you return it.

Lemon wedges
The Journal of Environmental Health discovered 70 percent of restaurants had contaminated bar fruit with microorganisms like E. coli, fecal bacteria, and other disease causing microbes. By opting out of the garnish for your beverage is a good way to prevent ingestion.

Condiment dispenser
Many people do not wash their hands before eating and they can spread their germs to bottles at the condiment stand. When grabbing for the ketchup, a paper napkin is not sufficient due to the abilities for microorganisms being able to pass through.

Restroom door handles
Don’t think you can escape the restroom without touching the door handle? Palm a spare paper towel after you wash up and use it to grasp the handle. Yes, other patrons may think you’re a germ-phobe–but you’ll never see them again, and you’re the one who won’t get sick.

Soap dispensers
About 25% of public restroom dispensers are contaminated with fecal bacteria. Soap that harbors bacteria may seem ironic, but that’s exactly what a recent study found. “Most of these containers are never cleaned, so bacteria grow as the soap scum builds up,” says Charles Gerba, PhD. “And the bottoms are touched by dirty hands, so there’s a continuous culture feeding millions of bacteria.” Be sure to scrub hands thoroughly with plenty of hot water for 15 to 20 seconds–and if you happen to have an alcohol-based hand sanitizer, use that, too.

Grocery carts
The handles of almost two-thirds of the shopping carts tested in a 2007 study at the University of Arizona were contaminated with fecal bacteria. In fact, the bacterial counts of the carts exceeded those of the average public restroom. Swab the handle with a disinfectant wipe before grabbing hold (stores are starting to provide them, so look around for a dispenser). And while you’re wheeling around the supermarket, skip the free food samples, which are nothing more than communal hand-to-germ-to-mouth zones.

Airplane bathrooms
When Gerba tested for microbes in the bathrooms of commercial jets, he found surfaces from faucets to doorknobs to be contaminated with E. coli. It’s not surprising, then, that you’re 100 times more likely to catch a cold when you’re airborne, according to a recent study in the Journal of Environmental Health Research. To protect yourself, try taking green tea supplements. In a 2007 study from the University of Florida, people who took a 450-milligram green tea supplement twice a day for 3 months had one-third fewer days of cold symptoms. The supplement brand used in the study was Immune Guard ($30 for 60 pills; immune-guard.us).

Doctor’s office
A doctor’s office is not the place to be if you’re trying to avoid germs. These tips can help limit your exposure.
1. Take your own books and magazines (and kid’s toys, if you have your children or grandchildren with you).

2. Also pack your own tissues and hand sanitizers, which should be at least 60% alcohol content.

3. In the waiting room, leave at least two chairs between you and the other patients to reduce your chances of picking up their bugs. Germ droplets from coughing and sneezing can travel about 3 feet before falling to the floor.

Source: ABCNews February 20, 2011

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Herbs & Plants Lentils

Cajanus cajan (Pegion pea)

Botanical Name :Cajanus cajan (Linn) Millsp.
Other scientific names:  Cystisus cajan, Cystisus pseudo-cajan  ,Cajan inodorum  ,Cajanus bicolor,Cajanus indicus
Family :Fabaceae

Genus: Cajanus
Species: C. cajan
Kingdom: Plantae
Division: Magnoliophyta
Class: Magnoliopsida
Order: Fabales

Synonyms:Cajanus indicus Spreng. (Valder 1895) and Cytisus cajan (Crawfurd 1852)

Common Names :Arhar, Red gram, Pigeon pea, Gablos (Tag.) ,Kadios (Mang., Tag., P. Bis.) ,Kagyos (Tag.) ,Kaldis (Ig., Ilk.)   Kagyas (Tag.) ,Kalios (Tag.) , Kardis (Ibn., Ilk., Ig.) ,Kidis (Ilk., Bon.) ,Kusia (Ig., If.) , Tabios (Bik., C. Bis.) ,Guandu (Brazil) .Pigeon pea (Engl.),toor dal or arhar dal (India), Congo pea or gungo pea (in Jamaica), Pois Congo (in Haiti), gandul (in Puerto Rico), gunga pea, or no-eye pea.   arhar dal  in Bengali


Habitat :
Probably native to India, pigeon pea was brought millennia ago to Africa where different strains developed. These were brought to the new world in post-Columbian times. Truly wild Cajanus has never been found; they exist mostly as remnants of cultivations. In several places Cajanus persists in the forest. The closest wild relative, Atylosia cajanifolia Haines, has been found in some localities in East India. Most other Atylosias are found scattered throughout India, while in North Australia a group of endemic Atylosia species grow. In Africa Cajanus kerstingii grows in the drier belts of Senegal, Ghana, Togo, and Nigeria. Pigeon peas occur throughout the tropical and subtropical regions, as well as the warmer temperate regions (as North Carolina) from 30°N to 30°S (Duke, 1981a). In settled areas throughout the Philippines: cultivated, semicultivated, and in some places, spontaneous.

Description:

It is  is a perennial herb.An erect, branched, hairy shrub, 1-2 meters high. Leaves are oblong-lanceolate to oblanceolate with three leaflets. Flowers are yellow, in sparse peduncled racemes, about 1.5 cm long. Pod is hairy, 4-7 cm long, 1 cm wide, containing 2-7 seeds.

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Cultivation:
The cultivation of the pigeon pea goes back at least 3000 years. The centre of origin is most likely Asia, from where it traveled to East Africa and by means of the slave trade to the American continent. Today pigeon peas are widely cultivated in all tropical and semi-tropical regions of both the Old and the New World. Pigeon peas can be of a perennial variety, in which the crop can last 3–5 years (although the seed yield drops considerably after the first two years), or an annual variety more suitable for seed production.

Pigeon peas are an important legume crop of rainfed agriculture in the semi-arid tropics. The Indian subcontinent, Eastern Africa and Central America, in that order, are the world’s three main pigeon pea producing regions. Pigeon peas are cultivated in more than 25 tropical and sub-tropical countries, either as a sole crop or intermixed with cereals such as sorghum (Sorchum bicolor), pearl millet (Pennisetium glaucum), or maize (Zea mays), or with other legumes, such as peanuts (Arachis hypogaea). Being a legume, the pigeon pea enriches soil through symbiotic nitrogen fixation.

The crop is cultivated on marginal land by resource-poor farmers, who commonly grow traditional medium- and long-duration (5–11 months) landraces. Short-duration pigeon peas (3–4 months) suitable for multiple cropping have recently been developed. Traditionally, the use of such input as fertilizers, weeding, irrigation, and pesticides is minimal, so present yield levels are low (average = 700 kg/ha). Greater attention is now being given to managing the crop because it is in high demand at remunerative prices.

Pigeon peas are very drought resistant and can be grown in areas with less than 650 mm annual rainfall.

World production of pigeon peas is estimated at 46,000 km2. About 82% of this is grown in India. These days it is the most essential ingredient of animal feed used in West Africa, most especially in Nigeria where it is also grown

Edible Uses: Vegetable food crop ( seeds and pods) in South-East Asia.Pigeon peas are both a food crop (dried peas, flour, or green vegetable peas) and a forage/cover crop. They contain high levels of protein and the important amino acids methionine, lysine, and tryptophan.  In combination with cereals, pigeon peas make a well-balanced human food. The dried peas may be sprouted briefly, then cooked, for a flavor different from the green or dried peas. Sprouting also enhances the digestibility of dried pigeon peas via the reduction of indigestible sugars that would otherwise remain in the cooked dried peas.

In India, split pigeon peas (toor dal) are one of the most popular pulses, being an important source of protein in a mostly vegetarian diet. In regions where it grows, fresh young pods are eaten as vegetable in dishes such as sambhar.

In Ethiopia, not only the pods but the young shoots and leaves are cooked and eaten.

CLICK  &  SEE  THE  PICTURES

In some places, such as the Dominican Republic and Hawaii, pigeon peas are grown for canning and consumption. A dish made of rice and green pigeon peas (called “Moro de Guandules”) is a traditional food in Dominican Republic. Pigeon peas are also made as a stew, with plantain balls. In Puerto Rico, arroz con gandules is made with rice and pigeon peas and is a typical dish.

In Thailand, pigeon peas are grown as a host for scale insects which produce lac.

Pigeon peas are in some areas an important crop for green manure, providing up to 40 kg nitrogen per hectare. The woody stems of pigeon peas can also be used as firewood, fencing and thatch.

Nutrition
Used mainly for its edible young pods and seeds.

Chemical constituents :
Roots are considered antihelminthic, expectorant, febrifuge, sedative, vulnerary.
Seeds are rich in carbohydrates (58%) and proteins (19%).
Fair source of calcium and iron; good source of vitamin B.
Chemical studies reveal: 2′-2’methylcajanone, 2′-hydroxygenistein, isoflavones, cajanin, cahanones, among many others.

Analysis of dhal (without husk) gave the following values: moisture, 15.2; protein, 22.3; fat (ether extract), 1.7; mineral matter, 3.6; carbohydrate, 57.2; Ca, 9.1; and P, 0.26%; carotene evaluated as vitamin A, 220 IU and vitamin B1, 150 IU per 100 g. Sun-dried seeds of Cajanus cajan are reported to contain (per 100 g) 345 calories, 9.9% moisture, 19.5 g protein, 1.3 g fat, 65.5 g carbohydrate, 1.3 g fiber, 3.8 g ash, 161 mg Ca, 285 mg P, 15.0 mg Fe, 55 mg b-carotene equivalent, 0.72 mg thiamine, 0.14 mg riboflavin, and 2.9 mg niacin. Immature seeds of Cajanus cajan are reported to contain per 100 g, 117 calories, 69.5% moisture, 7.2 g protein, 0.6 g fat, 21.3 g total carbohydrate, 3.3 g fiber, 1.4 g ash, 29 mg Ca, 135 mg P, 1.3 mg Fe, 5 mg Na, 563 mg K, 145 mg b-carotene equivalent, 0.40 mg thiamine, 0.25 mg riboflavin, 2.4 mg niacin, and 26 mg ascorbic acid/100 g. Of the total amino acids, 6.7% is arginine, 1.2% cystine, 3.4% histidine, 3.8% isoleucine, 7.6% leucine, 7.0% lysine, 1.5% methionine, 8.7% phenylalanine, 3.4% threonine, 2.2% tyrosine, 5.0% valine, 9.8 aspartic acid, 19.2% glutamic acid, 6.4% alanine, 3.6% glycine, 4.4% proline, 5.0% serine with 0 values for canavanine, citrulline and homoserine. Methionine, cystine, and tryptophane are the main limiting amino acids. However, in combination with cereals, as pigeon peas are always eaten, this legume contributes to a nutritionally balanced human food. The oil of the seeds contains 5.7% linolenic acid, 51.4% linoleic, 6.3% oleic, and 36.6% saturated fatty acids. Seeds are reported to contain trypsin inhibitors and chymotrypsin inhibitors. Fresh green forage contains 70.4% moisture, 7.1 crude protein, 10.7 crude fiber, 7.9 N-free extract, 1.6 fat, 2.3 ash. The whole plant, dried and ground contains 1,1.2% moisture, 14.8 crude protein, 28.9 crude fiber, 39.9 N-free extract, 1.7 fat, and 3.5 ash. (Duke, 1981a)

Medicinal Uses:
Parts used
Leaves, roots.

Folkloric:-
*Decoction or infusionn of leaves for coughs, diarrhea, abdominal pains.
*Tender leaves are chewed for aphthous stomatitis and spongy gums.
*Pulped or poulticed leaves used for sores.
*In Peru, leaves are used as an infusion for anemial, hepatitis, diabetes, urinary infections and yellow fever.
*In Argentina, leaves used for genital and skin problems; flowers used for bronchitis, cough and pneumonia.
*In China, as vermifuge, vulnerary; for tumors.
*In Panama, used for treatment of diabetes (See study below).
*In Indian folk medicine, used for a variety of liver disorders.



Other Uses:

As forage or hay.
Branches and stems for basket and fuel. (Source)

Often grown as a shade crop for tree crops or vanilla, a cover crop, or occasionally as a windbreak hedge. In Thailand and N. Bengal, pigeon pea serves as host for the scale insect which produces lac or sticklac. In Malagasy the leaves are used as food for the silkworm. Dried stalks serve for fuel, thatch and basketry. (Duke, 1981a).

Studies:-
RBC Sickling Inhibition: StudyClinical studies have reported seed extracts to inhibit red blood cell sickling and potential benefit for people with sickle cell anemia.

• Antiplasmodial constituents of Cajanus cajan: Study isolated two stilbenes, longistylin A and C and betulinic acid from the roots and leaves of CC and showed moderately high in vitro activity against Plasmodium falcifarum strain.

• Stilbenes / Neuroprotective / Alzheimer’s Disease: Study of stilbenes containing extract-fraction from C cajan showed significant amelioration of cognitive deficits and neuron apoptosis. Findings suggest sECC has a potential in the development of therapeutic agent to manage cognitive impairment associated with Alzheimer’s disease through increase choline acetyltransferase activity and anti-oxidative mechanism.

• Hypocholesterolemic Effect: Study on the stilbenes containing extract-fraction of CC showed a hypocholesterolemic effect possibly through enhancement of hepatic LDL-receptor and cholesterol 7-alpha-hydroxylase expression levels and bile acid synthesis.

Hyperglycemic Effect: Evaluation of traditional medicine: effects of Cajanus cajan L. and of Cassia fistula L. on carbohydrate metabolism in mice: Contradicting its traditional use for diabetes, CC did not have a hypoglycemic effect on sugar, instead at higher doses, it produced a hyperglycemic effect.

Antimicrobial: Study shows the organic solvent extracts to inhibit E coli, S aureus and S typhi and the aqueous extract were inhibitory to E coli and S aureus.

• Antimicrobial / Antifungal: Nigerian study on the antimicrobial effects of the ethanol and aqueous extracts of locally available plants, including C cajan, showerd inhibition against S aureus, P aeruginosa, E coli and C albicans. The extracts of C cajam produced wider zones of inhibition against C albicans.

• Hyperglycemic Effect: Study of the aqueous extract of C cajan leaves showed a hyperglycemic effect, suggesting a usefulness incontrolling hypoglycemia that may be due to excess of insulin or other hypoglycemic drugs.

• Hepatoprotective: (1) Study of the methanol-aqueous fraction of C cajan leaf extract showed it could prevent the chronically treated alcohol induced rat liver damage and presents a promise as a non-toxic herb for therapeutic use in alcohol-induced liver dysfunction. (2) Study in mice with carbon tetrachloride-induced liver damage showed the methanol extracts of B orellana, C cajan, G pentaphylla and C equisetifolia showed significant decrease in levels of serum markers, indicating the protection of hepatic cells in a dose-dependent manner.

Disclaimer : The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplement, it is always advisable to consult with your own health care provider.

Resources:
http://en.wikipedia.org/wiki/Pigeon_pea
http://www.stuartxchange.com/Kadios.html
http://vaniindia.org.whbus12.onlyfordemo.com/herbal/plantdir.asp

http://www.hort.purdue.edu/newcrop/duke_energy/Cajanus_cajun.html

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Insect Brains ‘are Source of Antibiotics’ to Fight MRSA

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Cockroaches, far from being a health hazard, could be a rich source of antibiotics.

A study of locust and cockroach brains has found a number of chemicals which can kill bugs like MRSA.

Scientists hope these could become a powerful new weapon to boost the dwindling arsenal of antibiotics used to treat severe bacterial infections.

The research was announced at a meeting of the Society for General Microbiology.

The researchers discovered nine different chemicals in the brains of locusts and cockroaches, which all had anti microbrial properties strong enough to kill 90% of MRSA (Methicillin-resistant Staphylococcus aureus) while not harming human cells.

Cockroaches have a reputation for tenacity and for thriving in dirty environments.

Simon Lee from Nottingham University is the author of the study. He said that it is this capacity to live in dirty, infectious conditions that mean insect brains contain these kinds of compounds.

“They must have some sort of defense against micro organisms. We think their nervous system needs to be continuously protected because if the nervous system goes down the insect dies. But they can suffer damage to their peripheral structures without dying,” he told BB News.

He hopes the compounds could go on to be used to treat multi drug resistant infections like E. Coli and MRSA which are becoming increasingly difficult to treat using some of the most powerful antibiotics available to medicine.

“A kill rate of 90% is very very high, and I diluted the substance down so there was only a minute amount there. Conventional antbiotics reduce the number of the bacteria and let your immune system cope with the rest. So to get something with such a high kill rate that is so potent at such a low dose is very promising,” he told BBC News.

The compound would need years of testing for safety and efficacy before any drugs developed from them could go on the market.

Source: BBC NEWS

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The Truth About the Super Bug

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The bug is actually a single-celled bacteria belonging to the Eschericia coli (E. coli) family. The species carries an enzyme called New Delhi metallo-beta—lactamase (NDM-1), which allows it to neutralise all known antibiotics and survive in their presence.

The enzyme was first isolated from a patient who had come to India for elective surgery. When he left, he took the “super bug” with him. No one knows how prevalent the organism is in India, as we do not have a centralised surveillance and reporting system that tracks hospital acquired infections and bacterial antibiotic resistance patterns.

Resistance is not a new phenomenon. Sulpha drugs and penicillin — the first antibiotics — were once hailed as “miracle” drugs. Today, they are hardly used. Overuse and misuse resulted in almost all bacteria becoming resistant to them.

If appropriate antibiotics are administered during a disease process caused by bacteria, the germs die. The host develops antibodies that help the body eliminate the weakened organisms.

E. coli has been around for thousands of years. That’s because the microorganisms developed “plasmids”, stable genetic elements composed of DNA or RNA. These help the bacteria grow resistance to chemicals and antibiotics. Once they have acquired this ability, they pass on the gene to other bacteria, even belonging to different species. Staphylococcus aureus and Klebsiella too have developed multiple drug resistance.

The outbreak of plague in Gujarat in 1994 killed hundreds. The state government realised the disease could be controlled by preventing rats from infesting human habitation and with appropriate antibiotic treatment. The situation was thus brought under control.

The spread of antibiotic resistance too can be controlled with combined concentrated effort. People are often “too busy” to consult a doctor when they are ill. The neighbourhood pharmacy then seems an attractive alternative. The man at the counter (often not a qualified pharmacist) dispenses antibiotics for coughs, colds, fever and diarrhoea. But there is often no rational or appropriate use of antibiotics.

Also, people sometimes do not complete the full course of a drug. They keep a few tablets, popping them for similar symptoms later or dispensing them to friends and relatives. A single dose may temporarily suppress the symptom. In a previously healthy person, the body’s natural defences then take over and eliminate the bacteria. The elderly or those with poor immunity become sicker, requiring the services of a qualified doctor. The bacteria, meanwhile, thrives in the presence of the antibiotic, because either they were not susceptible or the dosage was too small to be effective. Antibiotic resistance develops.

Practitioners of alternative systems of medicine prescribe and dispense antibiotics (which they are not licensed to use) inappropriately, perpetuating the problem.

At times, qualified physicians and surgeons use antibiotics prophylactically, especially after surgical procedures, to “prevent infection”. These antibiotics are eventually excreted by the body. They reach the sewage systems and seep through the earth. Bacteria are naturally present in sewage. They spread and multiply in the presence of the antibiotic.

Cattle and poultry feed are laced with antibiotics to “prevent” infection. Antibiotic resistant bacteria thrive on farms.

Everyone must play his or her part well to prevent another plague with super bugs which places the entire world population at risk.

• Take treatment only from qualified physicians

• Always buy antibiotics with a prescription, not OTC

• Complete the course in the dosage prescribed

Hygiene has to be maintained not just in the hospitals but also at home. Regularly washing hands, an elementary procedure, reduces infection and its spread.

Governments, nationally and internationally, need to maintain surveillance to monitor emerging infections and drug resistance patterns. If everyone — patients, doctors and the public — does not co-operate on a war footing, we may revert to the dark ages of the pre penicillin era. No antibiotic will work against infections and developing an infectious disease will turn out to be a death sentence.

An Article written by Dr Gita Mathai

Source: The Telegrtaph (Kolkata, India)

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