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Eating Broccoli Can Reduce Cancer Risk

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Eating a broccoli-rich diet can reduce the risk of deadly prostate cancer, according to researchers.

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What’s more, the consumption of one or more portions of the green veggie can lessen the risk of localized cancer becoming more aggressive.

In the study, the research group at the Institute of Food Research led by Professor Richard Mithen has provided an explanation of how eating broccoli might reduce cancer risk based upon studies in men, as opposed to trying to extrapolate from animal models.

Prostate cancer is the most common non-skin cancer for males in western countries. The research has provided an insight into why eating broccoli can help men stay healthy.

In the research, men who were at risk of developing prostate cancer, were made to eat either 400g of broccoli or 400g of peas per week in addition to their normal diet over 12 months.

Tissue samples were taken from their prostate gland before the start of the trial and after 6 and 12 months, and the expression of every gene measured using Affymetrix microarray technology.

It was found that there were more changes in gene expression in men who were on the broccoli-rich diet than on the pea diet, and these changes may be associated with the reduction in the risk of developing cancer, that has been reported in epidemiological studies.

Previous studies have suggested that the fifty per cent of the population who have a GSTM1 gene gain more benefit from eating broccoli than those who lack this gene. The study showed that the presence of the GSTM1 gene had a profound effect on the changes in gene expression caused by eating broccoli.

The results of the study suggested that relatively low amounts of cruciferous vegetables in the diet – a few portions per week – can have large effects on gene expression by changing cell-signaling pathways.

These signaling pathways are the routes by which information is transmitted through a molecular cascade, which amplifies the signal to the nucleus of the cell where gene expression occurs.

The study has been published in the online, open-access journal PLoS ONE on July 2

Sources:The Times Of India

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Ailmemts & Remedies

Testicular Cancer

Testicular cancer forms in a man’s testicles, the two egg-shaped glands that produce sperm and testosterone. Testicular cancer mainly affects young men between the ages of 20 and 39. It is also more common in men who

*Have had abnormal testicle development

*Have had an undescended testicle

*Have a family history of the cancer

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…………………………………Male reproductive systemTesticular lumps
.Symptoms include pain, swelling or lumps in your testicles or groin area. Most cases can be treated, especially if it is found early. Treatment options include surgery, radiation and/or chemotherapy. Regular exams after treatment are important. Treatments may also cause infertility. If you may want children later on, you should consider sperm banking before treatment.

Source:National Cancer Institute

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Click to learn more in detail about Testicular Cancer

Click to read BBC news on A laddish website for lads’ disease

How Can I Prevent Testicular Cancer?

Cause and Prevention of Testicular Cancer

Testicular Cancer – Prevention

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Fruits & Vegetables

1 Tomato, 2 Tomatoes, 3 Tomatoes, More!

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Italian-food lovers everywhere, rejoice: Tomato sauce is even healthier than previously suspected. Research is showing that tomatoes and tomato-based foods are excellent sources of lycopene, an antioxidant with cancer-fighting abilities; specifically, lycopene is believed to significantly reduce a man’s chances of getting prostate cancer. Prostate cancer is serious: It affects one in four men over age 50, who may suffer impotence and incontinence as a result, and is the second leading cause of cancer death in American men.

A six-year study of prostate cancer in 40- to 75-year-old men was recently published in the Journal of the National Cancer Institute as a follow-up to a previous six-year study. Nearly 50,000 men reported on the foods they ate so researchers could evaluate their intakes of lycopene-rich foods, including tomatoes and tomato sauces (e.g., pasta sauce and salsa); pizza; watermelon; and grapefruit.

Consuming tomato sauce (considered the best source of lycopene) more than twice per week reduced the odds for prostate cancer by about 25%, compared to consuming it less than once per month. A high estimated lycopene intake from any foods was also associated with a significant reduction in prostate cancer risk.

These data confirm previous reports of a reduced risk for prostate cancer through consuming tomato products and other sources of lycopene. Cooked tomatoes and tomato products, such as ketchup and various tomato sauces, are the optimal sources of lycopene.

Reference:

Giovannucci E, Rimm EB, Liu Y, et al. A prospective study of tomato products, lycopene, and prostate cancer risk. Journal of the National Cancer Institute 2002:94(5), pp. 391-398.

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