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Rotavirus Vaccine Reduces Diarrhea

An oral vaccine for diarrhea reduced hospitalizations of children with rotavirus by 70 percent in Philadelphia, saved money and prevented infections among unvaccinated children, researchers reported.

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Three reports presented to a meeting of infectious disease specialists showed the benefits of the vaccine, which prevents the most common cause of severe diarrhea.

In one report, Irini Daskalaki of Drexel University College of Medicine reported that hospitals in North Philadelphia had seen a 70 percent drop in rotavirus-associated hospitalizations since rotavirus vaccinations began in 2006.

The number of babies aged 6 to 11 months admitted to the hospital with rotavirus plummeted by 94 percent, Daskalaki told a meeting of the American Society of Microbiology and the Infectious Diseases Society of America.

“The extent of the decrease in cases … is unprecedented and greater than any variation in numbers previously observed, suggesting that the vaccine played an important role,” researchers wrote in a summary released before the presentation.

Merck and Co’s Rotateq was recommended in 2006 for routine immunization of U.S. infants, while GlaxoSmithKline Plc’s Rotarix, was approved by the U.S. Food and Drug Administration in April. Both are considered equally safe.

Rotavirus is the leading cause of severe gastroenteritis, with vomiting and diarrhea, in infants and young children.

Before routine vaccination, the condition sent 410,000 children to a doctor every year, with more than 200,000 needing emergency care and 20 to 60 dying in the United States.

Globally, rotavirus kills 1,600 children under age 5 every day.

Doctors had been desperate for a vaccine to prevent the highly contagious infection. But the first one, sold by Wyeth, was pulled from the market in 1999 after it was linked to a rare, life-threatening type of bowel obstruction known as intussusception.

The new vaccines do not have that problem. A team at the University of Texas Medical Branch in Galveston also found a 94 percent reduction in diarrheal disease after Rotateq was introduced.

Researchers at Children’s Mercy Hospital in Kansas City, Missouri, found only 62 children were admitted for rotavirus infection in 2008, compared with more than 300 a year in previous years, saving about $3 million a year in hospitalization costs.

A team at Quest Diagnostics, a company that tests lab samples, said it found evidence the vaccine lowered rotavirus infections in every state by between 18 and 87 percent.

“These data show a marked reduction in rotavirus disease in the U.S. after licensure of a live, oral rotavirus vaccine, although some states experienced greater declines than others,” they wrote in a summary.

“Evidence of herd immunity was also observed.” Herd immunity means even people who are not vaccinated are less likely to become infected because a disease is circulating less.

The Times Of India

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Hope Over High Blood Pressure Jab

A four-monthly jab may one day replace the need to regularly take pills to control blood pressure, scientists say.

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High blood pressure is a risk factor for heart disease

A team from the Swiss biotechnology firm Cytos found the vaccine against a hormone in the blood significantly cut blood pressure, the Lancet reported.

The jab was tested on 72 patients with high blood pressure and it was found to work without serious side-effects.

The researchers and independent experts said the findings were promising but large-scale trials were now needed.

High blood pressure, which affects a quarter of all adults, doubles the risk of dying from heart disease or stroke and is blamed for 60,000 deaths a year in UK.

Those who are being treated for it often have to take a daily course of pills to keep it under control.

But many people do not keep to their treatment regimes as people with high blood pressure do not display symptoms.

The researchers believe the vaccine, which works against the hormone angiotensin, which causes blood vessels to constrict and increase blood pressure, may offer a simple alternative.

They tested two different doses of the vaccine – 300 microgrammes and 100 microgrammes – as well as a dummy vaccine during the 14-week trial.


The jabs were given at the start, and after four weeks and 12 weeks – enough to give a patient four-month resistance.

Neither dose significantly lowered blood pressure at night.

But during the day the larger dose significantly lowered blood pressure, especially during the late morning peak when blood pressure is known to increase.

And, importantly, the vaccine did not have any serious side-effects with the worst being mild flu-like symptoms.

Lead researcher Dr Martin Bachmann said the vaccine could offer a much more simple way of controlling blood pressure and could be administered during regular visits to the doctor.

“Such a regimen is likely to promote adherence to treatment, but will need to be supported by clinical data.”

Professor Jeremy Pearson, of the British Heart Foundation, agreed more research was needed, but described the results as promising.

“Immunisation may be of particular benefit to people who find it difficult to stick to high blood pressure medication, but there is still a long way to go before this approach replaces the highly-effective current treatments.

“Looking after your heart through regular exercise, cutting down on salt, and only drinking in moderation remain the best ways in which we can prevent high blood pressure.”

Other firms are also known to be testing blood pressure vaccines.

Click to see also:->
High blood pressure set to soar

Hypertension trial stopped early

Finger test ‘spots heart disease’

Water ‘helps low blood pressure’

Warning over blood pressure drugs

Sleep drug lowers blood pressure

Gene clues to high blood pressure
Sources: BBC NEWS:7Th. March. ’08

Ailmemts & Remedies

Earache (Ear Infection)

Whether it’s a middle ear infection, located deep in the ear, or swimmer’s ear, affecting the outer ear canal, an earache hurts. It’s most often a problem in children, but adults get earaches too. Though some conditions clear up on their own, supplements can speed up the healing process….click & see


Throbbing or steady pain in ear; pain when pulling on lobe.
Pressure or itching in the ear.
A bloody, green, yellow, or clear discharge from the ear.
Muffled hearing; popping in ear.

When to Call Your Doctor
If earache is accompanied by fever over 101 F, stiff neck, severe headache, or seepage of pus or other fluids; or if the ear or area behind it appears red or swollen — it is likely an infection requiring antibiotics.

What It Is
An earache results from inflammation, infection, or swelling in the outer canal of the ear or in the space adjoining the eardrum, which is the thin membrane that separates the outer and the middle ear. Normally, the eustachian tube, which extends from the middle ear to the throat, drains fluids from the ear, keeping it clear. But inflammation or infection can irritate the ear canal or block the Eustachian tube, leading to the buildup of pus or other fluids and causing pain and other unpleasant symptoms.

What Causes It

Earaches are typically caused by harmful bacteria, viruses, or fungi, usually preceded by an upper respiratory infection or seasonal allergies, or moisture trapped in the ear. Other causes include excessive ear wax, sudden changes in air pressure, a punctured eardrum, or exposure to irritating chemicals, such as hair dyes and chlorinated water.

How Supplements Can Help
The supplements listed below can play a supportive role in healing earaches. They can be used in conjunction with antibiotics, pain relievers, and other conventional remedies for short-term treatment of mild to moderate ear discomfort. All severe, lingering, or recurrent ear pain, however, requires medical evaluation.

What Else You Can Do
Place a warm compress on the outside of your ear; use a heating pad or warm washcloth. Heat can bring quick pain relief and facilitate healing.
Never insert a cotton swab, which can puncture the eardrum, into your ear. Don’t use hydrogen peroxide as a cleaner; it can irritate the ear canal.
Herbal eardrops often bring rapid pain relief — within 10 minutes of administration. To make the application of drops more comfortable, warm the bottle under hot running tap water before placing the liquid in the ear.
Don’t smoke and avoid smoke-filled rooms, especially if you’re prone to earaches. The latest study to look at the link between secondhand smoke and ear infections reported that exposure to smoke can affect the ears. Children who lived in households with at least two smokers were 85% more likely to suffer from middle ear infections than those who lived in nonsmoking homes.

Supplement Recommendations

Garlic Oil
Mullein Flower Oil
Lavender Oil
Eucalyptus Oil
Vitamin A
Vitamin C/Flavonoids

Garlic Oil
Dosage: A few drops in the ear twice a day.
Comments: May be used alone or with mullein flower oil.

Mullein Flower Oil
Dosage: A few drops in the ear twice a day.
Comments: May be used alone or with garlic oil.

Lavender Oil
Dosage: Apply a few drops to the outer ear and rub in gently.
Comments: Can be used as needed throughout the day.

Eucalyptus Oil

Dosage: Add several drops essential eucalyptus oil to pan of water.
Comments: Bring oil and water to boil and remove from heat; place towel over head and pan and inhale steam through the nose.

Vitamin A
Dosage: 50,000 IU twice a day until symptoms improve; if needed after 7 days, reduce to 25,000 IU a day until symptoms are gone.
Comments: Women who are pregnant or considering pregnancy should not exceed 5,000 IU a day.

Vitamin C/Flavonoids
Dosage: 1,000 mg vitamin C and 500 mg flavonoids 3 times a day until infection clears.
Comments: Reduce vitamin C dose if diarrhea develops.

Dosage: 200 mg 3 times a day until infection clears.
Comments: Standardized to contain at least 3.5% echinacosides.

Source:Your Guide to Vitamins, Minerals, and Herbs (Reader’s Digest)

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.

News on Health & Science Pediatric

One Flu Shot May Offer ‘Whole Herd’ Protection

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Flu shots for elementary school children can help reduce flu like illness in the whole family, finds new research published in the New England Journal of Medicine this week. Doctors compared families and schools where, in some cases, the elementary school-age kids were offered free flu vaccination. Adults in the families of the vaccinated kids had fewer bouts of flu like illness, and they missed less work due to sickness in either themselves or their children. Elementary-age and high school age children were absent from school less frequently in families where at least one child was vaccinated. Researchers say that vaccinated kids are less likely to catch the flu and bring it home, thus offering “whole herd” protection to people around them.

Source      :ABC News

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Study links heartburn drugs to broken hip

Taking such popular heartburn drugs as Nexium, Prevacid or Prilosec for a year or more can raise the risk of a broken hip markedly in people over 50, a large study in Britain found.

The study raises questions about the safety of some of the most widely used and heavily promoted prescription drugs on the market, taken by millions of people.

The researchers speculated that when the drugs reduce acid in the stomach, they also make it more difficult for the body to absorb bone-building calcium. That can lead to weaker bones and fractures.

Hip fractures in the elderly often lead to life-threatening complications. As a result, doctors should make sure patients have good reason to stay on heartburn drugs long term, said study co-author Yu-Xiao Yang of the University of Pennsylvania School of Medicine.

“The general perception is they are relatively harmless,” Yang said. “They often are used without a clear or justified indication for the treatment.”

Source:The Times Of India