Categories
Herbs & Plants

Duhat-matsing

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Botanical Name :Polyalthia suberosa Roxb.
Family : Annonaceae
Other scientific names: Uvaria suberosa Roxb.  ,Phaeanthus cumingii Vidal ,Phaeanthus malabaricus
Common names Baling-manok (Tag.),  Lanutan (Tag.),Duhat-duhatan (Tag.,) Tagputagpuan (Tag.),Naves Duhat-matsing (Tag.) Munat (Ilk.),Duyat-nasi (Pamp.)

Habitat : Duhat-matsing is rather common in thickets at low and medium altitudes in Luzon (Cagayan to Laguna ); and in Mindanao. It also occurs in India to southern China and Malaya.

Description:
This is a Perennial  shrub or small tree growing to a height of 2 to 4 meters. The leaves are oblong to narrowly obovate-oblong and 5 to 11 centimeters long. The flowers are solitary, pale-yellow, 1 centimeters long or less, on slender pedicels, and 1 to 2 centimeters long. The sepals and petals are slightly hairy. The fruit is numerous, ovoid or globose, 4 to 5 millimeters long, purple, fleshy and edible.

You may click to see the pictures
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Edible uses:The fruits are eaten.
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Constituents
• Study yielded an azaanthracene alkaloid, kalasinamide, from the stems of P. suberosa., together with the known N-trans-feruloyltyramine and N-trans-coumaroyltyramine.
• Study isolated two new 2-substituted furans from the stems of P. suberosa.
Leaves contain alpha- and beta-amyrin, lupeol, beta-sitosterol, stigmasterol and campesterol. Stems and leaves contain triterpene, suberosol, which have shown anti-HIV replication activity. Stem bark yields alkaloids, oxostephanine and lanuginosine, which has shown antibacterial activity.

Properties
• Anti-HIV replication activity and antibacterial activity.

Medicinal Uses
Parts used : Fresh roots
Folkloric
Decoction of fresh roots used as abortifacient.

Studies

Furans / Antiviral Activity: 2-substituted furans from Polyalthia suberosa: Two new 2-substituted furans, 1-(2-furyl)pentacosa16,18-diyne and 23-(2-furyl)tricosa-5,7-diynoic acid, were isolated from the stems of P. suberosa. These compounds, with kalasinamide, N-trans-feruloyltyramine and N-trans-coumaroyltyramine showed anti-HIV activities.
• Anti-HIV Activity
: Anti-AIDS Agents, 9. Suberosol, a New C31 Lanostane-Type Triterpene and Anti-HIV Principle from Polyalthia suberosa: In the course of searching for anti-HIV agents, a new triterpene, suberosol, was isolated and studied for anti-HIV activity. (Publ.1993)
• Cytotoxic: Study isolated four new styryl-lactones, crassalactones A-D together with seven known compounds from an extract of leaves and twigs of PC. Cytotoxic evaluation against mammalian cancer lines were done on all the new isolates.

Disclaimer:
The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

Resources:
http://regionalconservation.org/ircs/database/plants/PlantPage.asp?TXCODE=Polysube

Click to access duhat-matsing.pdf


http://www.rspg.or.th/plants_data/kp_bot_garden/kpb_03-3.htm

Categories
Health Quaries

Some Health Quaries & Answers

 

Hole in my ear:
Q: I developed a hole in my eardrum and I think it is due to prolonged use of the mobile phone. I cannot manage without my phone.

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A:
The hole (perforation) in the ear drum is unlikely to have been caused by the use of a mobile phone. Usually it develops as a result of an ear infection (otitis media), an injury with a sharp object or a sudden loud sound near the ear. It needs to be evaluated. You should consult an ear, nose and throat (ENT) surgeon.

It may heal and close with antibiotics and the use of ear drops. A long-standing non-healing perforation may require an operation called a tympanoplasty.

In any case, why not use the speaker phones option?

Tingling feet :
Q: My 72 years old father, is a diabetic, whose blood sugar is well controlled by oral medications. He has a lot of discomfort in his lower legs and feet. He had consulted a neurologist and after certain tests was found to have neuropathy. Although he was given vitamin combinations he has had no relief.

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A: Diabetic neuropathy is a nerve disorder that can occur as a complication of diabetes usually if there is poor blood sugar control. It can cause problems with the sensation in the feet. The symptoms are numbness, pain, or tingling in the feet or lower legs. There may be difficulty in walking and balance.

The first step is to bring blood sugar levels under control. You could purchase a glucometer and check the sugar level regularly at home. Make sure he always wears well fitting shoes. Walking regularly, taking warm baths, or using elastic stockings may help relieve leg pain. Analgesics, low doses of antidepressants, and some anticonvulsant medication can be prescribed, in addition to vitamins, in severely affected individuals.

Potty tot
Q: I have a son who is three and half years old. He has been suffering from acute constipation for the last one year. He passes hard stool, with pain. Sometimes small amounts are passed 10-12 times a day. He eats well and his diet includes 1,000ml of milk, which I give in a bottle at night.

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A: The quantity of milk that you are giving is far in excess of what he requires. He needs only 400ml of milk a day at the very most. It can be split into two 200ml feeds, in the morning and evening, not at night. At three and a half years he is far beyond the stage of feeding bottles. Encourage bowel movement in the morning by making him sit in the toilet at a fixed time even if he does not feel the urge.

If the constipation persists a further evaluation with a paediatrician can be done to rule out thyroid deficiency or bowel malfunctions.

Worried about AIDs
Q: Does a married couple need to have sex with a condom? I want to prevent HIV infection in myself and my wife. I am worried about AIDS.

A: If either party has had prior sexual encounters, it is better to use a condom until you check for HIV and hepatitis B. It is better to check again after six months when the window period for HIV infection is over. If you go to a Voluntary Counselling and Testing Centre, the tests are free.

Married people need to use condoms as a contraceptive device if they wish to prevent pregnancy, or if one of the parties is HIV or HbAg positive (hepatitis B).

Seeking perfect eyesight :
Q: I want perfect eyesight. What diet should I eat and what can I do?

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A: Green leafy vegetables like spinach, beetroot, carrot and drumsticks help eyesight because of their vitamin and antioxidant content. Overcooking destroys heat sensitive labile beneficial vitamins of the B group. Steaming or microwave cooking vegetables or eating them raw is, therefore, better. Eating two raw tomatoes a day will give you all the vitamins you need.

There are eye exercises in yoga which, done regularly, help to maintain and improve your eyesight.

More children
Q: I am 41 and my wife is 35. We have an eight-year-old daughter. We decided to try for a son. Despite our best attempts over the last one year, we failed. Although my wife’s periods are irregular, no tests have been done. We have received all kinds of tablets from various doctors. Now we read that some of them have potentially dangerous side effects.

A: All medicines have some side effects even if they are aryuvedic, homeopathic or herbal. The tablets used to induce ovulation can be dangerous if given for too many cycles in improper doses.

Before proceeding consider the following:

• You already have a healthy daughter.

• Do you really want another child?

•Test yourself — do a semen analysis

• Do an ultrasound for your wife to see why the periods are irregular.

Sources: The Telegraph (Kolkata, India)

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Categories
News on Health & Science

Waking up Dormant HIV

World HIV/AIDS Awareness Day
Image by reflexblue via Flickr

HAART (highly active anti-retroviral therapy) has emerged as an extremely effective HIV treatment that keeps virus levels almost undetectable; however, HAART can never truly eradicate the virus as some HIV always remains dormant in cells. But, a chemical called suberoylanilide hydroxamic acid (SAHA), recently approved as a leukemia drug, has now been shown to ‘turn on’ latent HIV, making it an attractive candidate to weed out the hidden virus that HAART misses.
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Matija Peterlin at UCSF and colleagues had previously identified another chemical called HMBA that could activate latent HIV, but the risk of several toxic side effects made HMBA clinically non-viable. However, the chemically similar SAHA had received FDA approval, making it a potentially safer alternate.

So, the researchers examined whether SAHA had any effect on HIV latency. They found that SAHA could indeed stimulate latent HIV to begin replicating, which exposes the infected cell to HAART drugs. SAHA could activate HIV in both laboratory cells as well as from blood samples taken from HIV patients on antiretroviral therapy. Importantly, this successful activation was achieved using clinical doses of SAHA, suggesting toxicity will not be a problem.

Sources
:http://www.asbmb.org/News.aspx?id=2286