Categories
Herbs & Plants

Goldenseal

Botanical Name : Hydrastis canadensis
Family: Ranunculaceae
Genus: Hydrastis
Species: H. canadensis
Kingdom: Plantae
Order: Ranunculales

Common Names:  Goldenseal, yellow paint root, orange root, yellow puccoon, ground raspberry, eye root, yellow Indian plant, turmeric root, Ohio curcuma, eye balm, yellow eye and jaundice root.

Habitat :Goldenseal is native to North America, and can be found growing wild from Ontario to Arkansas, across the southeastern U.S. to Georgia and cultivated in Oregon and Washington. The main growing region used to be Ohio valley, before it became the area fell victim to deforestation and development.
It grows in the rich soil of shady woods and moist places at the edge of wooded lands. Goldenseal prefers open hardwood forests, with rich humic soils, and a slight slope around 5% to facilitate drainage. Plants are found to be most vigorous in stands with 60-65% shade, and pH values between 5.5 and 6.5.

Description:
Goldenseal has a thick, yellow rootstock which sends up an erect hairy stem about 1 foot in height which branches near the top, one branch bearing a large leaf and another a smaller leaf and a flower.The stem is purplish and hairy above ground and yellow below ground where it connects to the yellow rhizome. The plant bears two palmate, hairy leaves with 5–7 double-toothed lobes and single, small, inconspicuous flowers with greenish white stamens in the late spring.

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The rhizome is thick, sarcous, oblong, irregular, and knotted, having a yellowish-brown, thin bark, and a bright-yellow interior; rootlets numerous, scattered, coriaceous fibres.This low perennial herb grows from 6 to 10 inches high, its leaves and fruit much resembling those of the raspberry. The flowering stem, which is pushed up early in the spring, is from 6 to 12 inches high, erect, cylindrical, hairy, with downward-pointing hairs, especially above, surrounded at the base with a few short, brown scales. It bears two prominently-veined and wrinkled, dark green, hairy leaves, placed high up, the lower one stalked, the upper stalkless, roundish in outline, but palmately cut into 5 to 7 lobes, the margins irregularly and finely toothed. The flower, which is produced in April, is solitary, terminal, erect, and small, with three small greenish-white sepals, falling away immediately after expansion, no petals and numerous stamens.It bears a single berry like a large raspberry with 10–30 seeds. The fruit ripens in July and has the superficial appearance of a raspberry, with small, fleshy, red berries, tipped with the persistent styles and containing 1 or 2 black, shiny seeds. However, it is not edible.

Cultivation:
Goldenseal can be grown both from seed and from the rhizome. It requires a partially shaded situation (60 – 70%), in a well draining, rich humus soil. Rootstocks can be divided into small pieces and set at least 8” apart. Planting should be undertaken in the autumn. The plants should be allowed to grow for 2 – 3 years before harvesting, though by the 4th year the roots are said to become too fibrous for medicinal use. Transplanting may be undertaken at any time. According to an American grower 32 healthy plants set per square yard will produce 2 lb of dry root after three years of growth. The fresh rhizome is juicy and loses much of its weight in drying. When fresh, it has a well-marked, narcotic odour, which is lost in a great measure by age, when it acquires a peculiar sweetish smell, somewhat resembling liquorice root. It has a very bitter, feebly opiate taste, more especially when freshly dried. The rhizome is irregular and tortuous, much knotted, with a yellowish-brown, thin bark and bright yellow interior, 1/2 inch to 1 1/2 inch long, and from 1/8 to 1/4 inch thick. The upper surface bears short ascending branches, which are usually terminated by cup-like scars, left by the aerial stems of previous years. From the lower surface and sides, numerous thin, wiry, brittle roots are given off, many of them breaking off, leaving small protuberances on the root. The colour of the rhizome, though yellow in the fresh root, becomes a dark, yellowish brown by age; that of the rootlets and the interior of the root are yellow and that of the powder still more so. When dry, the rhizome is hard and breaks with a clean, resinous fracture, the smooth, fractured surface is of a brownish-yellow, or greenish-yellow colour, and exhibits a ring of bright yellow, somewhat distant narrow wood bundles surrounding large pith.

Constituents:
Goldenseal contains the isoquinoline alkaloids: hydrastine, berberine, berberastine, hydrastinine, tetrahydroberberastine, canadine, and canalidine. A related compound, 8-oxotetrahydrothalifendine was identified in one study. One study analyzed the hydrastine and berberine contents of twenty commercial goldenseal and goldenseal-containing products and found they contained variously 0%-2.93% hydrastine and 0.82%-5.86% berberine.[18] Berberine and hydrastine act as quaternary bases and are poorly soluble in water but freely soluble in alcohol. The herb seems to have synergistic antibacterial activity over berberine in vitro, possibly due to efflux pump inhibitory activity.

Multiple bacteria and fungi, along with selected protozoa and chlamydia are susceptible to berberine in vitro. Berberine alone has weak antibiotic activity in vitro since many microorganisms actively export it from the cell (although a whole herb is likely to work on the immune system as well as on attacking the microbes and hence have a stronger clinical effect than the antibiotic activity alone would suggest).[citation needed] Interestingly, there is some evidence for other berberine-containing species synthesizing an efflux pump inhibitor that tends to prevent antibiotic resistance, a case of solid scientific evidence that the herb is superior to the isolated active principle. However, it is not yet known whether goldenseal contains a drug resistance efflux pump inhibitor, although many antimicrobial herbs do.

Medicinal Uses:
•The American aborigines valued the root highly as a tonic, tomachic and application for sore eyes and general ulceration.
•It is a valuable remedy in the disordered conditions of the digestion and has a special action on the mucous membrane, making it of value as a local remedyin various forms of catarrh.
•The action is tonic, laxative, alterative and detergent. The powder has proved useful as a snuff for nasal catarrh.
•It is employed in dyspepsia, gastric catarrh, and loss of appetite and liver troubles.
•Goldenseal was used by the American Indians as a treatment for irritations and inflammation of the mucous membranes of the respiratory, digestive, and urinary tracts.
•Its traditional uses include treatment of peptic ulcers, gastritis, dyspepsia and colitis.
•It is said to stimulate appetite and generally have a toning effect on the whole body.
•Its astringent properties have also been employed in cases of excessive menstruation and internal bleeding. It has a stimulating effect on the uterine muscles for which it is sometimes used as an aid in childbirth.
•The decoction is also said to be effective as a douche to treat trichomonas and thrush. As a gargle it can be employed in cases of gum infections and sore throats.
•It was commonly used topically for skin and eye infections.
•It is used for infectious diarrhea, upper respiratory tract infections, and vaginal infections.
•It is used as aremedy for laxative, tonic, alterative, detergent, opthalmicum, antiperiodic, aperient, diuretic, antiseptic, deobstruent.
•Excels for open sores, inflammations, eczema, ringworm, erysipelas, skin diseases, and nausea during pregnancy.
•In combination with skullcap and red pepper it will relieve and strengthen the heart.
•The Iroquois made a decoction of roots for treatment of whooping cough and diarrhea, liver trouble, fever, sour stomach and gas and as an emetic for biliousness. They also prepared a compound infusion with other roots for use as drops in the treatment of earache and as a wash for sore eyes.

Known Hazards:  Goldenseal is considered safe at recommended dosages.But it may cause side effects allergic reaction, headache and many others. Not safe for pregnant women and children.

Other Uses:
•Mixed with bear’s grease it is said to have been used as an insect repellent.
•Native people also valued the yellow roots as a stain and dye

Folklore and Myths:
It is believed that Goldenseal root is a very rare and expensive botanical Curio widely thought to be a powerful Guardian and Healer and to provide Strength and Protection to those who possess it.  Goldenseal root is used by many people for the purpose of Warding off Evil and bringing Good Luck in Health Matters. Some folks says that they place Goldenseal  root in a white flannel bag along with Angelica Root and other Healing Herbs, anoint this conjure hand with 7-11 Holy Type Oil or Blessing Oil and sew it into the mattress of any loved one who suffers chronic pain, serious disease, or acute illness, for Protection and Healing.

Disclaimer : The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplement, it is always advisable to consult with your own health care provider.

Resources:
http://en.wikipedia.org/wiki/Goldenseal
http://www.indianmirror.com/ayurveda/goldenseal.html
http://www.medicalhealthguide.com/herb/goldenseal.htm

Categories
Herbs & Plants

Menispermum Canadense

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Botanical Name : Menispermum Canadense
Family: Menispermaceae
Genus: Menispermum
Species: M. canadense
Kingdom: Plantae
Order: Ranunculales

Synonyms: Canadian Moonseed. CoTexas Sarsaparilla. Moonseed Sarsaparilla. Vine Maple.

Common Names :Canadian Moonseed, Common Moonseed, or Yellow Parilla

Habitat:  Menispermum Canadense  is native to Eastern N. America – Quebec and New England to Georgia, west to Arkansas and Oklahoma.  It grows on moist woods and hedges near streams. Deciduous woods and thickets, along streams, bluffs and rocky hillsides, fencerows, shade tolerant from sea level to 700 metres.

Description:
It is a woody deciduous climbing vine growing to 6 m tall. The leaves palmately lobed, 5–20 cm diameter with 3-7 shallow lobes, occasionally rounded and unlobed.  It is in flower from Jun to July, and the seeds ripen from Oct to November The fruit are produced in 6–10 cm diameter clusters of purple-black berries, each berry is 1-1.5 cm in diameter. The seed inside the berry resembles a crescent moon, and is responsible for the common name. The fruit is ripe between September and October, the same general time frame in which wild grapes are ripe.The flowers are dioecious (individual flowers are either male or female, but only one sex is to be found on any one plant so both male and female plants must be grown if seed is required)The plant is not self-fertile.

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Both the leaves and fruit resemble that of the Fox Grape (Vitis labrusca); confusion can be dangerous as Moonseed fruit is poisonous, unlike the edible Fox Grape fruit.

The root is a rhizome, with a very long root of a fine yellow colour, and a round, striate stem, bright yellowgreen when young; leaves, roundish, cordate, peltate, three to seven angled, lobed. Flowers small, yellow, borne in profusion in axillary clusters. Drupes, round, black, with a bloom on them, one-seeded. Seed, crescent-shaped, compressed, the name Moonseed being derived from this lunate shape of the seed. The rhizome is wrinkled longitudinally and has a number of thin, brittle roots; fracture, tough, woody; internally reddish; a thick bark encloses a circle of porous, short, nearly square wood wedges and a large central pith. The root is the official part; it has a persistent bitter, acrid taste and is almost inodorous.

Cultivation:
Succeeds in any moderately fertile soil that does not dry out excessively in summer, in sun or partial shade. Prefers a position in full sun[219]. This species is hardy to about -30°c, but, due to a lack of summer heat, the plants usually produce soft growth in mild maritime areas and this can be cut to the ground at temperatures around -5 to -10°c. The plants do not require pruning, but can benefit from being cut back to ground level every 2 – 3 years in order to keep them tidy. A vigorous and fast-growing climbing plant that twines around supports, it also spreads freely by underground suckers. Dioecious. Male and female plants must be grown if seed is required.

Propagation :
Seed – sow late winter in a greenhouse. Two months cold stratification speeds up germination so it might be better to sow the seed as soon as it is ripe in a cold frame. Germination is usually good. When they are large enough to handle, prick the seedlings out into individual pots and grow them on in the greenhouse for at least their first winter. Plant them out into their permanent positions in late spring or early summer, after the last expected frosts. Cuttings of mature wood, autumn in a frame. Division of suckers in early sprin. The suckers can be planted out direct into their permanent positions, though we prefer to pot them up and grow them on in light shade in a greenhouse or cold frame until they are established.

Medicinal Uses:

Parts Used: The rhizome and roots.
Constituents: Berberine and a white amorphous alkaloid termed Menispermum, which has been used as a substitute for Sarsaparilla, some starch and resin.

Canada moonseed has occasionally been used in the past for its medicinal virtues, though it is little, if at all, used in modern herbalism. The roots are a bitter tonic, diuretic, laxative, nervine, purgative (in large doses), stomachic and tonic. A tea made from the root has been used in the treatment of indigestion, arthritis, bowel disorders and as a blood cleanser. The root is applied externally as a salve on chronic sores.

In small doses it is a tonic, diuretic, laxative and alterative. In larger doses it increases the appetite and action of the bowels; in full doses, it purges and causes vomiting. It is a superior laxative bitter; considered very useful in scrofula, cutaneous, rheumatic, syphilitic, mercurial and arthritic diseases; also for dyspepsia, chronic inflammation of the viscera and in general debility. Externally, the decoction has been applied as an embrocation in cutaneous and gouty affections.

Use with caution, see notes above on toxicity.

 Other Uses:Cultivated in Britain as a hardy, deciduous, ornamental shrub. A closely allied species is indigenous to the temperate parts of Eastern Asia.

Known Hazards:  All parts of these plants are known to be poisonous. The principal toxin is the alkaloid dauricine. The fruit of Canada Moonseed are poisonous and can be fatal. While foraging for wild grapes one should examine the seeds of the fruit to make sure one is not eating moonseeds: moonseeds have a single crescent-shaped seed, while grapes have round seeds. Differences in taste should also be an indicator of whether or not a specimen is grape or Moonseed, moonseeds have a taste that is described as “rank”. Also, the moonseed vine lacks tendrils, whilst the vine of the wild grape has forked tendrils.

Disclaimer:
The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

Resources:
http://en.wikipedia.org/wiki/Menispermum_canadense
http://www.botanical.com/botanical/mgmh/p/parill07.html

http://www.pfaf.org/user/Plant.aspx?LatinName=Menispermum+canadense

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News on Health & Science

SOME INFORMATION ABOUT CANCER CELL

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1. Every person has cancer cells in the body. These cancer cells do not show up in the standard tests until they have multiplied to a few billion. When doctors tell cancer patients that there are no more cancer cells in their bodies after treatment, it just means the tests are unable to detect the cancer cells because they have  not reached the detectable size.

2. Cancer cells occur between 6 to more than 10 times in a person’s lifetime.

3. When the person’s immune system is strong the cancer cells will be destroyed and prevented from multiplying and forming tumors.

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4. When a person has cancer it indicate the person has multiple nutritional deficiencies. These could be due to genetic, environmental, food and lifestyle factors.

5. To overcome the multiple nutritional deficiencies, changing diet and including supplements will strengthen the immune system.

6. Chemotherapy involves poisoning the rapidly-growing cancer cells and also destroys rapidly-growing healthy cells in the bone marrow, gastro-intestinal tract etc, and can cause organ damage, like liver, kidneys, heart, lungs etc.

7. Radiation while destroying cancer cells also burns, scars and damages healthy cells, tissues and organs.

8. Initial treatment with chemotherapy and radiation will often reduce tumor size. However prolonged use of chemotherapy and radiation do not result in more tumor destruction.

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9. When the body has too much toxic burden from chemotherapy and radiation the immune system is either compromised or destroyed, hence the person can succumb to various kinds of infections and complications.

 10. Chemotherapy and radiation can cause cancer cells to mutate and become resistant and difficult to destroy. Surgery can also cause cancer cells to spread to other sites.

11. An effective way to battle cancer is to STARVE the cancer cells by not feeding it with foods it needs to multiple.

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What cancer cells feed on:  

a. Sugar is a cancer-feeder. By cutting off sugar it cuts off one important food supply to the cancer cells. Note: Sugar substitutes like NutraSweet, Equal, Spoonful, etc are made with Aspartame and it is harmful. A better natural substitute would be Manuka honey or molasses but only in very small amounts. Table salt has a chemical added to make it white in colour. Better alternative is Bragg’s aminos or sea salt. Protein having with 9 amino acids is more helpful whose PDCAAS score is 1.0.

b. Milk causes the body to produce mucus, especially in the gastro-intestinal tract. Cancer feeds on mucus. By cutting off milk and substituting with unsweetened soy milk, cancer cells will starved. High source of Fiber is more helpful.

c. Cancer cells thrive in an acid environment. A meat-based diet is acidic and it is best to eat fish, and a little chicken rather than beef or pork. Meat also contains livestock antibiotics, growth hormones and parasites, which are all harmful, especially to people with cancer. Protein having with 9 amino acids is more helpful whose PDCAAS score is 1.0.

d. A diet made of 80% fresh vegetables and juice, whole grains, seeds, nuts and a little fruits help put the body into an alkaline environment. About 20% can be from cooked food including beans. Fresh vegetable juices provide live enzymes that are easily absorbed and reach down to cellular levels within 15 minutes t o nourish and enhance growth of healthy cells. Good sources of Vitamins & Minerals are more effective.

To obtain live enzymes for building healthy cells try and drink fresh vegetable juice (most vegetables including bean sprouts) and eat some raw vegetables 2 or 3 times a day. Enzymes are destroyed at temperatures of 104 degrees F (40 degrees C). High contain of Vitamin “C” (like Accelera Cherry) is also more helpful.

e. Avoid coffee, tea, and chocolate, which have high caffeine. Green tea is a better alternative and has cancer-fighting properties. Water–best to drink purified water, or filtered, to avoid known toxins and heavy metals in tap water. Distilled water is acidic, avoid it.

12. Meat protein is difficult to digest and requires a lot of digestive enzymes. Undigested meat remaining in the intestines will become putrified and leads to more toxic buildup. Protein having with 9 amino acids is more helpful whose PDCAAS score is 1.0.

13. Cancer cell walls have a tough protein covering. By refraining from or eating less meat it frees more enzymes to attack the protein walls of cancer cells and allows the body’s killer cells to destroy the cancer cells.

14. Some supplements build up the immune system (IP6, Flor-ssence, Essiac, anti-oxidants, vitamins, minerals, EFAs etc.) to enable the body’s own killer cells to destroy cancer cells. Other supplements like vitamin E are known to cause apoptosis, or programmed cell death, the body’s normal method of disposing of damaged, unwanted, or unneeded cells.

15. Cancer is a disease of the mind, body, and spirit. A proactive and positive spirit will help the cancer warrior be a survivor.

Anger, unforgiving and bitterness put the body into a stressful and acidic environment. Learn to have a loving and forgiving spirit. Learn to relax and enjoy life.

16. Cancer cells cannot thrive in an oxygenated environment. Exercising daily, and deep breathing help to get more oxygen down to the cellular level. Oxygen therapy is another means employed to destroy cancer cells.

Click  & read : Delivering cancer drugs, bang on target   

Source:Information  received through an email

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Herbs & Plants

Centaurea nigra

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Botanical Name :Centaurea nigra
Family: Asteraceae
Tribe: Cynareae
Genus: Centaurea
Species: C. nigra
Kingdom: Plantae
Order: Asterales

Common Names:Lesser Knapweed, Common Knapweed and Black Knapweed. A local vernacular name is Hardheads.

Habitat:Centaurea nigra  is native to western Europe, including Britain, from Spain to Norway, east to Germany and Switzerland. It grows in grassland, waysides, cliffs etc to 600 metres.

Description:
Centaurea nigra is a perennial herb growing up to about a metre in height.

The leaves are up to 25 centimetres long, usually deeply lobed, and hairy. The lower leaves are stalked, whilst the upper ones are stalkless.

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The inflorescence contains a few flower heads, each a hemisphere of black or brown bristly phyllaries. The head bears many small bright purple flowers. The fruit is a tan, hairy achene 2 or 3 millimetres long, sometimes with a tiny, dark pappus. Flowers July until September.

Flowers sometimes are yellow, or white.Important for Gatekeeper butterfly, Goldfinch, Honey bee, Large skipper, Lime-speck pug moth, Meadow Brown, Painted lady, Peacock, Red admiral, Small copper, Small skipper

Cultivation:
Succeeds in ordinary garden soil. Prefers a well-drained fertile soil and a sunny position. Tolerates dry, low fertility and alkaline soils. Established plants are tolerant of considerable neglect, thriving and even self-sowing in dense weed growth. Members of this genus are rarely if ever troubled by browsing deer.

Propagation :
Seed – sow April in a cold frame. When they are large enough to handle, prick the seedlings out into individual pots and plant them out into their permanent positions in the summer. Division in autumn. Very easy, larger clumps can be replanted direct into their permanent positions, though it is best to pot up smaller clumps and grow them on in a cold frame until they are rooting well. Plant them out in the summer or following spring. This should be done at least once every three years in order to maintain the vigour of the plant. Basal cuttings in spring. Harvest the shoots when they are about 10 – 15cm long with plenty of underground stem. Pot them up into individual pots and keep them in light shade in a cold frame or greenhouse until they are rooting well. Plant them out in the summer.
Edible Uses: Flower petals are eaten raw. Added to salads

Medicinal Uses:

The roots and seeds are diaphoretic, diuretic, tonic and vulnerary. The plant once had a very high reputation as a healer of wounds. A medieval wound salve.  Used to soothe sore throats and bleeding gums.

Disclaimer:
The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

Resources:
http://en.wikipedia.org/wiki/Centaurea_nigra
http://www.herbnet.com/Herb%20Uses_IJK.htm
http://www.ct-botanical-society.org/galleries/centaureanigr.html

http://www.pfaf.org/user/Plant.aspx?LatinName=Centaurea+nigra

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Ailmemts & Remedies

Sepsis

Alternative Names: Systemic inflammatory response syndrome (SIRS),blood poisoning or septicaemia.

Definition:
Sepsis is a bacterial infection of the blood.It is a severe illness in which the bloodstream is overwhelmed by bacteria.While sepsis can happen to anyone, it’s most common and most dangerous in people who are elderly or who have weakened immune systems.

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Sepsis occurs when chemicals released into the bloodstream to fight the infection trigger inflammation throughout the body. This inflammation creates microscopic blood clots that can block nutrients and oxygen from reaching organs, causing them to fail. If sepsis progresses to septic shock, blood pressure drops dramatically and the person may die.

Early treatment of sepsis, usually with antibiotics and large amounts of intravenous fluids, improves chances for survival.

Symptoms:
In addition to symptoms related to the provoking infection, sepsis is characterized by presence of acute inflammation present throughout the entire body, and is, therefore, frequently associated with fever and elevated white blood cell count (leukocytosis) or low white blood cell count and lower-than-average temperature, and vomiting. The modern concept of sepsis is that the host’s immune response to the infection causes most of the symptoms of sepsis, resulting in hemodynamic consequences and damage to organs. This host response has been termed systemic inflammatory response syndrome (SIRS) and is characterized by an elevated heart rate (above 90 beats per minute), high respiratory rate (above 20 breaths per minute or a partial pressure of carbon dioxide in the blood of less than 32), abnormal white blood cell count (above 12,000, lower than 4,000, or greater than 10% band forms) and elevated or lowered body temperature, i.e. under 36 °C (97 °F) or over 38 °C (100 °F). Sepsis is differentiated from SIRS by the presence of a known or suspected pathogen. For example SIRS and a positive blood culture for a pathogen indicates the presence of sepsis. However, in many cases of sepsis no specific pathogen is identified.

This immunological response causes widespread activation of acute-phase proteins, affecting the complement system and the coagulation pathways, which then cause damage to the vasculature as well as to the organs. Various neuroendocrine counter-regulatory systems are then activated as well, often compounding the problem. Even with immediate and aggressive treatment, this may progress to multiple organ dysfunction syndrome and eventually death.

Causes:
Sepsis is often a complication of another infection, such as of the lungs or kidneys, and occurs when the bacteria escape that part of the body and get into the bloodstream.

This bacteria can also come from burns, infected wounds, boils and tooth abscesses. Sometimes it isn’t obvious how it has got into your blood.

Anyone can develop sepsis. The people most at risk are those with weakened immune systems, because of an existing illness, for example, or medication.

Older people, children and intravenous drug users are also more susceptible.

In children, sepsis may accompany infection of the bone (osteomyelitis). In hospitalized patients, common sites of infection include intravenous lines, surgical wounds, surgical drains, and sites of skin breakdown known as bedsores (decubitus ulcers).

Risk Factors:
Sepsis is more common and more dangerous in people who:

*Are very young or very old
*Have compromised immune systems
*Are already very sick, often in a hospital’s intensive care unit
*Have invasive devices, such as intravenous catheters or breathing tubes

Complication:
As sepsis worsens, blood flow to vital organs, such as your brain, heart and kidneys, becomes impaired. Sepsis can also cause blood clots to form in your organs and in your arms, legs, fingers and toes — leading to varying degrees of organ failure and tissue death (gangrene).

Most people recover from mild sepsis, but the mortality rate for severe sepsis or septic shock is close to 50 percent.

Diagnosis:
The infection is often confirmed by a blood test. However, a blood test may not reveal infection in people who have been receiving antibiotics.

Other tests that may be done include:
•Blood gases
•Kidney function tests
•Platelet count
•White blood cell count
•Blood differential
•Fibrin degradation products
•Peripheral smear

Treatment;
Early, aggressive treatment boosts your chances of surviving sepsis. People with severe sepsis require close monitoring and treatment in a hospital intensive care unit. If one has severe sepsis or septic shock, lifesaving measures may be needed to stabilize breathing and heart function.

Medications
A number of different types of medications are used in treating sepsis. They include:

*Antibiotics. Treatment with antibiotics begins immediately — even before the infectious agent is identified. Initially you’ll receive broad-spectrum antibiotics, which are effective against a variety of bacteria. The antibiotics are administered intravenously (IV). After learning the results of blood tests, your doctor may switch to a different antibiotic that’s more appropriate against the particular bacteria causing the infection.

*Vasopressors. If your blood pressure remains too low even after receiving intravenous fluids, you may be given a vasopressor medication, which constricts blood vessels and helps to increase blood pressure.

*Others. Other medications you may receive include low doses of corticosteroids, insulin to help maintain stable blood sugar levels, drugs that modify the immune system responses, and painkillers or sedatives.Therapy

People with severe sepsis usually receive supportive care including oxygen and large amounts of intravenous fluids. Depending on your condition, you may need to have a machine help you breathe or dialysis for kidney failure.

Surgery
Surgery may be needed to remove sources of infection, such as collections of pus (abscesses).

Prognosis:
This section requires expansion.

Prognosis can be estimated with the Mortality in Emergency Department Sepsis (MEDS) score.  Approximately 20–35% of patients with severe sepsis and 40–60% of patients with septic shock die within 30 days. Others die within the ensuing 6 months. Late deaths often result from poorly controlled infection, immunosuppression, complications of intensive care, failure of multiple organs, or the patient’s underlying disease.

Prognostic stratification systems such as APACHE II indicate that factoring in the patient’s age, underlying condition, and various physiologic variables can yield estimates of the risk of dying of severe sepsis. Of the individual covariates, the severity of underlying disease most strongly influences the risk of death. Septic shock is also a strong predictor of short- and long-term mortality. Case-fatality rates are similar for culture-positive and culture-negative severe sepsis.

Some patients may experience severe long-term cognitive decline following an episode of severe sepsis, but the absence of baseline neuropsychological data in most sepsis patients makes the incidence of this difficult to quantify or to study. A preliminary study of nine patients with septic shock showed abnormalities in seven patients by MRI.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.
Resources:
http://www.mayoclinic.com/health/sepsis/DS01004
http://www.nlm.nih.gov/medlineplus/ency/article/000666.htm
http://en.wikipedia.org/wiki/Sepsis
http://www.bbc.co.uk/health/physical_health/conditions/sepsis.shtml
http://www.humenhealth.com/sepsis/sepsis.asp
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