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A Big Bottom Can Cut Diabetes Risk

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Here’s some good news for women who find it hard to squeeze into their skinny jeans, courtesy their big bottoms: a generously proportioned derriere could be good for health, say scientists.
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Accord to research, the fat in buttocks and hips may protect against type 2 diabetes.

Scientists at Harvard Medical School in America reckon that the type of fat that accumulates around the hips and bottom may offer some protection against developing the condition.

Fat found commonly around the lower areas, known as subcutaneous fat, or fat that collects under the skin, helps to improve the sensitivity of the hormone insulin. Insulin is responsible for regulating blood sugar and therefore a big bottom might offer some protection against diabetes.

The boffins said that fat which collects around the stomach can raise a person’s risk of diabetes and heart disease. But, people with pear-shaped bodies, with fat deposits in the buttocks and hips, are less prone to these disorders.

Lead researcher Dr Ronald Kahn said that the research on mice had shown that not all fat was bad and could help to prevent the onset of Type 2 diabetes.

The team is trying to find the substances produced in subcutaneous fat that provide the benefit because they could lead to the development of drugs, reports the Daily Express.

The study was published in the journal Cell Metabolism.

Sources:The Times Of India

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Does Thinking Make You Fatter?

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A research team has demonstrated that intellectual work induces a substantial increase in appetite and calorie intake. This discovery could help to explain, in part, the current obesity epidemic.

The team measured the spontaneous food intake of 14 students after each of three tasks: relaxing in a sitting position, reading and summarizing a text, and completing a series of memory, attention, and vigilance tests on the computer.

Each session of intellectual work required only three calories more than the rest period. However, despite the low energy cost of mental work, the students spontaneously consumed 203 more calories after summarizing a text and 253 more calories after the computer tests than they did after relaxing.

Blood samples taken before, during, and after each session revealed that intellectual work caused bigger fluctuations in glucose and insulin levels — two critical components in the body’s regulatory and energy machinery — than rest periods.

Jean-Philippe Chaput, the lead author of the study, said that mental work “destabilizes” the levels of insulin and glucose, thus stimulating the appetite, apparently in response to a need to restore the body’s energy balance.
Sources:
ABC News September 10, 2008
Psychosomatic Medicine September 2008 70:797-804

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Pumpkin may treat diabetics

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The common vegetable Pumpkin will now be more tastier than ever as Chinese scientists have claimed that it can “drastically” reduce the need for daily insulin injections for millions of diabetic patients worldwide.

Scientists have discovered a compound in pumpkin that has been known to promote the regeneration of damaged insulin-producing beta cells in diabetic rats, thereby improving the level of insulin in their blood.

Laboratory data showed that diabetic rats that had been fed pumpkin extract had only five per cent less plasma insulin and eight per cent fewer insulin-positive cells than normal healthy rats, according to a research paper published this week in the US-based Journal of the Science of Food and Agriculture.

The researchers fed 12 diabetic rats and 12 normal rats either a normal diet or a diet supplemented with pumpkin extract for 30 days.

On average, the rats receiving the pumpkin supplements experienced a 36 per cent increase in plasma insulin compared to the untreated rats, Professor Xia Tao, the paper’s lead author and a teacher at Shanghai‘s East China Normal University said.

However, Xia, a professor at the College of Life Science, emphasised that further research was needed to evaluate the effects in human beings.

“But I tend to believe pumpkin extract could also promote regeneration of pancreatic beta cells in humans,” he was quoted as saying by China Daily

Source:The Times Of India

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A bitter sweet problem

The global incidence of diabetes is increasing. It has already affected 2.8 per cent of the total population and this is expected to increase to 4.8 per cent in 2008. In absolute figures this works out to an increase to 366 million from 171 million. These projected figures are expected to hold good even if the all-pervading epidemic of obesity, inactivity and urbanisation remains static.

Frightening statistics, these. Aware of this, the medical community has put a great deal of time and effort into the elucidation of cause and effect.

What really causes diabetes? No one still has an answer. Everything has been blamed — heredity, genes, the environment, upbringing, breast-feeding, immunisation and immunity. Infection with viruses, especially those of the coxackie group, chemical toxins and even some allergens found in cow’s milk are believed to precipitate the development of antibodies to the cells in the pancreas that produce insulin. This leads to destruction and an eventual decrease in the total number of cells left to produce insulin.

Whatever the cause, the end result is the same. The blood sugar goes up and produces macro vascular complications in all the organs of the body. This predisposes a person to the development of stroke, heart attacks and even amputation of a limb. At the micro level, it affects the eyes, the kidneys and the nerves.

Before the discovery of insulin, diabetics led a miserable existence, controlled with an almost intolerable rigid regimen of diet and exercise. Many succumbed to infection or developed fatal biochemical abnormalities because of the high, uncontrolled sugar.

The discovery of insulin changed all that. It helped diabetics achieve control and this in turn has reduced the risk of eye, kidney, nerve and cardiovascular diseases. Diabetics are beginning to live longer and healthier lives.

Diabetes is now a more accepted as a lifestyle disease. Control with diet and exercise is preferred, and this can now be individualised. Patients can play a greater role in the control and management of the disease.
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The diet is no longer regimentalised as people are now able to modify their eating according to their needs. A 1,500 -2,000 calorie-a-day diet split over six meals probably helps to achieve good control.

There is no need to totally avoid food such as rice, bread, cereal and starchy vegetables. Instead, spread out the total content in six small meals instead of three big ones.

A total of five fruits or vegetables can be eaten daily and an extra piece of fruit when the hunger pangs are unbearable.

There is no real need to feel guilty if you have eaten a sweet. Moderation is the key. Cheating once or twice a week is acceptable. Just remember that sweets push up the sugar rapidly.

Initially, for a (young or old) diabetic with some pancreatic function, a controlled sensible diet and regular exercise may be enough to manage the escalating sugar level.

Later oral medications may have to be added. Here too, patient friendly developments have occurred. Sustained release, long-acting medications or the newer once-a-day medications are now available.

After five-six years on tablets, control often begins to slip. At this point in time, switching to insulin is a realistic, sensible long-term option. The old allergy-causing painful pork and cow insulins have now been replaced with human insulin analogues. They are painless, can be long or short acting, dosages are smaller, and absorption is good. There are no more ugly lumps, bumps or disfiguring atrophic areas betraying the sites of insulin injections.

The old syringes and needles, too, have been replaced with ultra light “pens” (available for between Rs 200-300). The medication comes in a cartridge, very much like pen refill cartridges. If even that is a problem, for a slightly higher price a “use and throw” disposable version is available.

For those with poor coordination and eyesight, the numbers indicating the dosage in the pens are large. It is difficult to withdraw too much or too little as it preset. The pens “lock” and only the required amount of insulin is injected each time.

Visits to the physician or the lab may be difficult and time consuming. That probably means the blood values are probably only done once in every couple of months. This type of control is not satisfactory. At that time a glycosylated haemoglobin (HbA1c) value (normal 3.7-5.1) can be checked instead. This reveals control over the past couple of months.

It is better to achieve individualised good day-to-day control with tailored minor adjustments in diet, medication and injections. This is now easily done with home glucometers (Rs 1,500), now available with a three-year guarantee. Sugar levels can be checked once or twice a day so that an erratic indulgent meal or lack of physical activity never pushes the diabetes out of control.

Are you diabetic? You hold your life (with a little help) in the palm of your hand.

By Dr Gita Mathai who is a paediatrician with a family practice at Vellore,India. Questions on health issues may be emailed to her at yourhealthgm@yahoo.co.in

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