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Calculator Tells the Bald Future

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A pioneering new computer programme that predicts if and when men will go bald is being offered to British men.

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The “baldness calculator” — said to be the world’s first reliable tool for predicting hair loss — has been a huge hit with men.

The programme calculates the exact age at which someone will go bald or have lost most of their hair or provides reassurance by predicting that they will still have a full head of hair in old age.

More than half a million German men used it within ten days of it being unveiled there and three million men have tried it out globally so far.

Sixty per cent of users of the calculator to date have been young men aged between 15 and 30. Two thirds of all British men will eventually suffer hair loss, according to recent research.

The programme asks users about their age, marital status, occupation, where they live, what their current hairline is, hair loss in their family and their stress levels.

German scientists devised the programme because half of men in their country suffer from hereditary hair loss.

Adolf Klenk, head of research and development at hair care firm Dr Kurt Wolff, said: “More and more men value full hair but especially younger men.

“They are looking for a partner and are at the peak of their social lives. They are very conscious about their looks and being accepted within their social groups. They get concerned that if they lose their hair, they will cease to be attractive to others whereas older men don’t care so much.”

Klenk said that men with a history of hair loss on either their mother or father’s side of the family are most at risk of going bald.

Source:The Daily Telegraph

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News on Health & Science

The New Bone Cement

New Bone Cement to Prevent Dangerous Injury Infections:-

…..
Osteomyelitis (OM) is a dangerous bacterial bone infection that often occurs in patients with open fractures. So it is not surprising that injured American soldiers serving in Afghanistan and Iraq have been getting OM, with an end result sometimes being a limb amputation. Now researchers from the Center for Musculoskeletal Research in Rochester with help from the Department of Orthopedics at Aarhus University Hospital in Denmark, Infectious Disease Service at Brooke Army Medical Center in San Antonio, and Heraeus Medical GmbH, created a new colistin-infused bone cement that is showing itself to be effective against the variety of bacterial pathogens that cause OM. Interestingly, Stryker already has a bone cement that features colistin, a product called Simplex P with Erythromycin & Colistin.

From a press statement by the University of Rochester Medical Center:
Not common in the United States and not potentially fatal, A. baumannii OM had been largely ignored until recently by physicians and the pharmaceutical industry, which focuses on life-threatening infections that affect millions, not hundreds. Then military outbreaks of the infection started among American soldiers returning from Iraq in 2003, with the number of A. baumannii OM infections seen in field hospitals, and in stateside facilities receiving injured soldiers, growing. At the same time, data began to emerge from hospitals treating soldiers suggesting that easily contracted A. baumannii may be arriving first at the fracture site and “priming” it so that it becomes more vulnerable to methicillin-resistant Staphylococcus aureus (MRSA), which recently surpassed HIV as the most deadly pathogen in the United States despite nearly universal use of the best available antibiotics.
“If you apply the findings from two small studies to the entire U.S. military, which is a leap, perhaps 2,000 soldiers come into field hospitals with compound fractures each year that become infected with A. baumannii,” said Edward Schwarz, Ph.D., professor of Orthopaedics within the Center for Musculoskeletal Research at the University of Rochester Medical Center. “About a third of them go on to get a staph infection after they reach the hospital, with about a third of those, perhaps 200 soldiers, suffering infectious complications that could cost them a limb. Studies already underway in our lab seek to clarify how the initial infections could gradually be replaced by catastrophic MRSA, and to prove that we can save limbs by putting an established antibiotic into bone cement for the first time.”

Approaches commonly used to overcome MDR [multi-drug resistant] infections after orthopaedic injuries include applying a large dose of antibiotic locally to the site of infection via bone cement. Bone cements composed of Plexiglas (polymethyl methacrylate or PMMA) have been used for decades for plastic surgery, to anchor in bone prostheses and to fill in holes in bone caused by trauma. Such materials became even more useful when researchers realized decades ago that they could load them with antibiotics to deliver large doses of drug directly to the injury site without subjecting the whole body to toxic levels of antibiotic. While bone cements laced antibiotics against staph and strep infections are common (e.g. vancomycin), no group had ever developed a bone cement treatment using colistin against A. baumannii.

Schwarz and colleagues developed a group of mice infected with drug resistant A. baumannii strains isolated directly from soldiers wounded in Iran and Afghanistan. The mice were then treated with either colistin by injection, local colistin via PMMA bead bone cement or a bone cement control with no drug.

Researchers measured the amount of bacteria in the mice as they responded to treatment with a new test of parC gene activity, a gene known to be present only in A. baumannii. Experiments confirmed that all study mice were infected with the bacteria, and that 75 percent of the strains were resistant to multiple antibiotics. Importantly, the bone cement containing colistin significantly reduced the infection rate such that only 29.2 percent of mice had detectable levels of parC after 19 days (p<0.05 vs. i.m. colistin and placebo). Colistin via injection failed to control the infection and was no better than placebo.

You may click to see:->

Press release: New Bone Cement May Prevent Amputations

Flashback: Rapid-Sequencing the Superbug

Sources:http://www.medgadget.com/archives/2009/01/new_bone_cement_to_prevent_dangerous_battle_injury_infections.html

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Herbs & Plants

Lovage

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Botanical Name: Levisticum officinale (KOCH.)
Family: Apiaceae
Tribe:     Apieae
Genus:     Levisticum
Species: L. officinale
Kingdom: Plantae
Order:     Apiales

Synonyms: Ligusticum Levisticum (Linn.). Old English Lovage. Italian Lovage. Cornish Lovage. In Germany and Holland, one of the common names of Lovage is Maggikraut (German) or Maggiplant (Dutch) because the plant’s taste is reminiscent of Maggi soup seasoning. In Romania the common name of Lovage is LeuÅŸtean.

Parts Used:
Root, leaves, seeds, young stems.
Habitat: It is not considered to be indigenous to Great Britain, and when occasionally found growing apparently wild, it is probably a garden escape. It is a native of the Mediterranean region, growing wild in the mountainous districts of the south of France, in northern Greece and in the Balkans.

The Garden Lovage is one of the old English herbs that was formerly very generally cultivated, and is still occasionally cultivated as a sweet herb, and for the use in herbal medicine of its root, and to a less degree, the leaves and seeds.
It is a true perennial and hence is very easy to keep in garden cultivation; it can be propagated by offsets like Rhubarb, and it is very hardy. Its old-time repute has suffered by the substitution of the medicinally more powerful Milfoil and Tansy, just as was the case when ‘Elecampane‘ superseded Angelica in medical use. The public-house cordial named ‘Lovage,’ formerly much in vogue, however, owed such virtue as it may have possessed to Tansy. Freshly-gathered leafstalks of Lovage (for flavouring purposes) should be employed in long split lengths.

Description: Lovage is an erect, herbaceous, perennial plant growing to 1.8–2.5 m tall, with a basal rosette of leaves and stems with further leaves, the flowers being produced in umbels at the top of the stems. The stems and leaves are shiny glabrous green to yellow-green and smell of lime when crushed. The larger basal leaves are up to 70 cm long, tripinnate, with broad triangular to rhomboidal, acutely pointed leaflets with a few marginal teeth; the stem leaves are smaller, and less divided with few leaflets. The flowers are yellow to greenish-yellow, 2–3 mm diameter, produced in globose umbels up to 10–15 cm diameter; flowering is in late spring. The fruit is a dry two-parted schizocarp 4–7 mm long, mature in autumn.

The large, dark green radical leaves, on erect stalks, are divided into narrow wedge-like segments, and are not unlike those of a coarse-growing celery; their surface is shining, and when bruised they give out an aromatic odour, somewhat reminiscent both of Angelica and Celery. The stems divide towards the top to form opposite whorled branches, which in June and July bear umbels of yellow flowers, similar to those of Fennel or Parsnip, followed by small, extremely aromatic fruits, yellowish-brown in colour, elliptical in shape and curved, with three prominent winged ribs. The odour of the whole plant is very strong. Its taste is warm and aromatic, and it abounds with a yellowish, gummy, resinous juice.

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It is sometimes grown in gardens for its ornamental foliage, as well as for its pleasant odour, but it is not a striking enough plant to have claimed the attention of poets and painters, and no myths or legends are connected with it. The name of the genus, Ligusticum, is said to be derived from Liguria, where this species abounds.

Cultivation: Lovage is of easy culture. Propagation is by division of roots or by seeds. Rich moist, but well-drained soil is required and a sunny situation. In late summer, when the seed ripens, it should be sown and the seedlings transplanted, either in the autumn or as early in spring as possible, to their permanent quarters, setting 12 inches apart each way. The seeds may also be sown in spring, but it is preferable to sow when just ripe. Root division is performed in early spring.

The plants should last for several years, if the ground be kept well cultivated, and where the seeds are permitted to scatter the plants will come up without care.

Constituents: Lovage contains a volatile oil, angelic acid, a bitter extractive, resins, etc. The colouring principle has been isolated by M. Niklis, who gives it the name of Ligulin, and suggests an important application of it that may be made in testing drinking water. If a drop of its alcoholic or aqueous solution is allowed to fall into distilled water, it imparts to the liquid its own fine crimson-red colour, which undergoes no change; but if limestone water be substituted, the red colour disappears in a few seconds and is followed by a beautiful blue, due to the alkalinity of the latter.

Medicinal Action and Uses: Formerly Lovage was used for a variety of culinary purposes, but now its use is restricted almost wholly to confectionery, the young stems being treated like those of Angelica, to which, however, it is inferior, as its stems are not so stout nor so succulent.

The leafstalks and stem bases were formerly blanched like celery, but as a vegetable it has fallen into disuse.

A herbal tea is made of the leaves, when previously dried, the decoction having a very agreeable odour.

Lovage was much used as a drug plant in the fourteenth century, its medicinal reputation probably being greatly founded on its pleasing aromatic odour. It was never an official remedy, nor were any extravagant claims made, as with Angelica, for its efficacy in numberless complaints.

The roots and fruit are aromatic and stimulant, and have diuretic and carminative action. In herbal medicine they are used in disorders of the stomach and feverish attacks, especially for cases of colic and flatulence in children, its qualities being similar to those of Angelica in expelling flatulence, exciting perspiration and opening obstructions. The leaves eaten as salad, or infused dry as a tea, used to be accounted a good emmenagogue.

An infusion of the root was recommended by old writers for gravel, jaundice and urinary troubles, and the cordial, sudorific nature of the roots and seeds caused their use to be extolled in ‘pestilential disorders.’ In the opinion of Culpepper, the working of the seeds was more powerful than that of the root; he tells us that an infusion ‘being dropped into the eyes taketh away their redness or dimness…. It is highly recommended to drink the decoction of the herb for agues…. The distilled water is good for quinsy if the mouth and throat be gargled and washed therewith…. The decoction drunk three or four times a day is effectual in pleurisy…. The leaves bruised and fried with a little hog’s lard and laid hot to any blotch or boil will quickly break it.’

Several species of this umbelliferous genus are employed as domestic medicines. The root of LIGUSTICUM SINENSE, under the name of KAO-PÂU, is largely used by the Chinese, and in the north-western United States the large, aromatic roots of LIGUSTICUM FILICINUM (OSHA COLORADO COUGH-ROOT) are used to a considerable extent as stimulating expectorants.

The old-fashioned cordial, ‘Lovage,’ now not much in vogue, though still occasionally to be found in public-houses, is brewed not only from the Garden Lovage, Ligusticum levisticum, but mainly from a species of Milfoil or Yarrow, Achillea ligustica, and from Tansy, Tanacetum vulgare,  and probably owes its merit more to these herbs than to Lovage itself. From its use in this cordial, Milfoil has often been mistakenly called Lovage, though it is in no way related to the Umbellifer family.

Several other plants have been termed Lovage besides the true Lovage, and this has frequently caused confusion. Thus we have the SCOTCH LOVAGE, known also as Sea Lovage, or Scotch Parsley, and botanically as Ligusticum scoticum; the BLACK LOVAGE, or Alexanders, Smyrnium Olusatrum; BASTARD LOVAGE, a species of the allied genus, Laserpitum, and WATER LOVAGE, a species of the genus Cenanthe.

Laserpitum may be distinguished from its allies by the fruit having eight prominent, wing-like appendages. The species are perennial herbs, chiefly found in south-eastern Europe. Some of them are employed as domestic remedies, on account of their aroma.

The scent of the root of MEUM ATHAMANTICUM (Jacq.), SPIGNEL (also called Spikenel or Spiknel), MEU or BALD-MONEY, has much in common with that of both Lovage and Angelica, and the root has been eaten by the Scotch Highlanders as a vegetable. It is a perennial, smooth and very aromatic herb. The elongated root is crowned with fibres, the leaves, mostly springing from the root, are divided into leaflets which are further cut into numerous thread-like segments, which gives them a feathery appearance. The stem is about 6 or 8 inches high, and bears umbels of white or purplish flowers. The aromatic flavour of the leaves is somewhat like Melilot, and is communicated to milk and butter when cows feed on the herbage in the spring. The peculiar name of this plant, ‘Baldmoney,’ is said to be a corruption of Balder, the Apollo of the northern nations, to whom the plant was dedicated.

Lovage is a plant, the leaves and “seeds” or fruit of which are used to flavor food, especially in South European cuisine. It is a tall (3 to 9 ft) perennial that vaguely resembles its cousin celery in appearance and in flavor. Lovage also sometimes gets referred to as smallage, but this is more properly used for celery.

The fruit of the lovage plant can be used as a spice, but what appears in the trade as lovage seed is usually ajwain, not lovage. On the other hand, what is sold as “celery seed” is often partially or entirely ground lovage seed.

The root of lovage, which is a heavy, volatile oil, is used as a mild aquaretic. Lovage root contains furanocoumarins which can lead to photosensitivity.Preparations made from the roots or leaves are used to treat edema, indigestion and to prevent the formation of kidney stones.

Disclaimer:
The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

References:
http://botanical.com/botanical/mgmh/l/lovage42.html
http://en.wikipedia.org/wiki/Lovage

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