Categories
News on Health & Science

Key To Way Stomach Expands Found

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Scientists believe they may have found a potential new way to treat obesity by stopping the stomach from expanding….CLICK & SEE

…….The stomach expands to accommodate the food we eat

They have identified two cell proteins that relax the gut and help accommodate a big meal.

In theory, a drug which blocked this relaxation would reduce a person’s ability and desire to gorge on excessive amounts of food.

The University College London study appears in the Journal of Pharmacology and Experimental Therapeutics.

The two proteins identified by the researchers P2Y1 and P2Y11 – control both fast and slow relaxations of the gut.

The human stomach has a “resting” internal volume of 75 millilitres, but by relaxing its muscular wall can expand to an internal volume of two litres or more.

This expansion is controlled by nerves inside the stomach wall which release molecules that stimulate P2Y1 and P2Y11, which are embedded in muscle cells, also in the gut wall.

New approach :

Researcher Dr Brian King said: “The mechanism of slow relaxation of the stomach might represent a future drug target in the fight to control weight gain and reverse obesity.

“We are looking to identify drugs that would block the P2Y11 receptor and, therefore, prevent slow relaxation of the stomach.

“As a result of blocking the P2Y11-based mechanism, meal size would be smaller, offering the person a better chance of regulating their food intake.”

Dr King said this would represent a new approach to weight control.

At present, gastric banding or stomach stapling are used to reduce the maximum volume of the stomach.

But these are tricky surgical procedures, and carry a risk of serious side effects.

Dr Ian Campbell, medical director of the charity Weight Concern, agreed that an alternative treatment for obesity would be useful.

He said major surgery such as gastric banding was expensive and risky, and although current drugs that focused on appetite suppression, or on reducing fat absorption by the body did work, their long term effects remained unclear.

“We still have much to learn about the complex way we control our appetite, and food intake,” he said.

“For many the use of medication can be an important help towards their weight loss goals, but lifestyle change remains the best way of controlling weight.”

Click to see:->Weight Concern and National Obesity Forum

Sources: BBC NEWS:3rd.March.’08

Categories
Ailmemts & Remedies

Constipation In Children

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Constipation means that bowel movements are hard and dry, difficult or painful to pass, and less frequent than usual. It is a common problem for children, but it is usually temporary and no cause for parents to be concerned.

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When a child does not eat enough fiber, drink enough liquids, or get enough exercise, constipation is more likely to occur. It also happens when children ignore the urge to have a bowel movement, which they often do out of embarrassment to use a public bathroom, fear or lack of confidence in the absence of a parent, or unwillingness to take a break from play. Sometimes constipation is caused by medicines or a disease.

Symptoms of constipation include:

  • no bowel movement for several days or daily bowel movements that are hard and dry
  • cramping abdominal pain
  • nausea
  • vomiting
  • weight loss
  • liquid or solid, clay-like stool in the child’s underwear—a sign that stool is backed up in the rectum

Constipation can make a bowel movement painful, so the child may try to prevent having one. Clenching buttocks, rocking up and down on toes, and turning red in the face are signs of trying to hold in a bowel movement.

Treatment depends on the child’s age and the severity of the problem. Often eating more fiber (fruits, vegetables, whole-grain cereal), drinking more liquids, and getting more exercise will solve the problem. Sometimes a child may need an enema to remove the stool or a laxative to soften it or prevent a future episode. However, laxatives can be dangerous to children and should be given only with a doctor’s approval.

Although constipation is usually harmless, it can be a sign or cause of a more serious problem. A child should see a doctor if

  • episodes of constipation last longer than 3 weeks
  • the child is unable to participate in normal activities
  • small, painful tears appear in the skin around the anus
  • a small amount of the intestinal lining is pushed out of the anus (hemorrhoids)
  • normal pushing is not enough to expel stool
  • liquid or soft stool leaks out of the anus

For More Information

American Academy of Pediatrics
National Headquarters
141 Northwest Point Boulevard
Elk Grove Village, IL 60007–1098
Phone: 847–434–4000
Fax: 847–434–8000
Internet: www.aap.org

International Foundation for Functional Gastrointestinal Disorders (IFFGD) Inc.
P.O. Box 170864
Milwaukee, WI 53217–8076
Phone: 1–888–964–2001 or 414–964–1799
Fax: 414–964–7176
Email: iffgd@iffgd.org
Internet: www.iffgd.org

Additional Information on Constipation in Children

The National Digestive Diseases Information Clearinghouse collects resource information on digestive diseases for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Reference Collection. This database provides titles, abstracts, and availability information for health information and health education resources. The NIDDK Reference Collection is a service of the National Institutes of Health.

To provide you with the most up-to-date resources, information specialists at the clearinghouse created an automatic search of the NIDDK Reference Collection. To obtain this information, you may view the results of the automatic search on Constipation in Children.

If you wish to perform your own search of the database, you may access and search the NIDDK Reference Collection database online.

National Digestive Diseases Information Clearinghouse

2 Information Way
Bethesda, MD 20892–3570
Phone: 1–800–891–5389
Fax: 703–738–4929
Email: nddic@info.niddk.nih.gov
Internet: www.digestive.niddk.nih.gov

The National Digestive Diseases Information Clearinghouse (NDDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The NIDDK is part of the National Institutes of Health of the U.S. Department of Health and Human Services. Established in 1980, the Clearinghouse provides information about digestive diseases to people with digestive disorders and to their families, health care professionals, and the public. The NDDIC answers inquiries, develops and distributes publications, and works closely with professional and patient organizations and Government agencies to coordinate resources about digestive diseases.

Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts.

This publication is not copyrighted. The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired.

Ayurvedic Treatment for child Constipation………………(A).……..(B)………..(C)

Home Remedy for Child Constipation…………………………(A).……..(B)

Homeopathic Treatment for Child Constipation………….(A).……..(B)………….(C)

Chiropractic view on Constipation.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies

Source:http://digestive.niddk.nih.gov/ddiseases/pubs/constipationchild/index.htm

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