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Stress a Trigger for Skin Disease

Researchers from University of Medicine Berlin and McMaster University in Canada have found that stress may activate immune cells in the skin, leading to inflammatory skin disease.

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This cross talk between stress perception, which involves the brain, and the skin is mediated through the “brain-skin connection”.

The immune cells in skin can over-react, resulting in inflammatory skin diseases like atopic dermatitis and psoriasis.

Study leader Petra Arck hypothesized that stress could exacerbate skin disease by increasing the number of immune cells in the skin.

The researcher said that the team exposed mice to sound stress, and found that the stress challenge resulted in higher numbers of mature white blood cells in the skin.

Moreover, blocking the function of two proteins that attract immune cells to the skin, LFA-1 and ICAM-1, prevented the stress-induced increase in white blood cells in the skin.

Based on their observations, the researchers came to the conclusion that stress activates immune cells, which in turn are central in initiating and perpetuating skin diseases. The study by Arck appears in the November issue of The American Journal of Pathology.

Sources: The Times Of India

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Western Diet Ups Heart Attack Risk

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Diets that are rich in fried and salty foods increase heart attack risk, while eating lots of fruit, leafy greens and other vegetables reduces it, a groundbreaking study showed.
Western diet boosts colon cancer risk by 300 per cent .

6/12/2008 – (NaturalNews) People who eat a typical “Western diet” or drink diet soda have a higher risk of developing metabolic syndrome and cardiovascular disease, according to a study published in the journal Circulation. “This is a red-alert wake-up call,”…

Green’s The Way: People who ate a ‘Prudent Diet’ — high in fruits and vegetables — had a 30% lower risk of heart attack…..CLICK & SEE

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The study, called Interheart, looked at 16,000 heart attack patients and controls between 1999 and 2003 in countries on every continent, marking a shift from previous studies which have focussed on the developed world.

The patients and controls filled in a “dietary risk score” questionnaire based on 19 food groups, which contained healthy and unhealthy items and were tweaked to include dietary preferences of each country taking part in the study.

The researchers found that people who eat a diet high in fried foods, salty snacks, eggs and meat — the “Western Diet” — a 35% greater risk of having a heart attack than people who consumed little or no fried foods or meat, regardless of where they live.

People who ate a “Prudent Diet” — high in leafy green vegetables, other raw and cooked vegetables, and fruits — had a 30% lower risk of heart attack than those who ate little or no fruit and veg, the study showed.

The third dietary pattern, called the “Oriental Diet” because it contained foods such as tofu and soy sauce which are typically consumed in Asian societies, was found to have little impact on heart attack risk.

Although some items in the Oriental diet might have protective properties such as vitamins and anti-oxidants, others such as soy sauce have a high salt content which would negate the benefits, the study said. The study was groundbreaking in its scope and because previous research had focused mainly on developed countries, according to Salim Yusuf, a senior author of the study.

“We had focussed research on the West because heart disease was mainly predominant in western countries 25-30 years ago,” Yusuf, who is a professor of medicine at McMaster University in Canada, said.

“But heart disease is now increasingly striking people in developing countries. Eighty percent of heart disease today is in low- to middle-income countries” partly because more people around the world are eating western diets, he said.

“This study indicates that the same relationships that are observed in western countries exist in different regions of the world,” said Yusuf, who is also head of the Population Health Research Institute at Hamilton Health Sciences in Ontario.

The main countries in the study were Argentina, Brazil, Chile and Colombia in South America; Canada and US in North America; Sweden in western Europe; and Egypt, Iran and Kuwait for the Middle East. Nearly all of South Asia — India, Pakistan, Bangladesh, Nepal and Sri Lanka — took part.

Sources: The Times Of India

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