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Odontoma

Odontoma is a benign tumor that usually forms at the root of a tooth. It may have genetic origins or may result from some sort of trauma to the tooth.
It  is a hamartoma of odontogenic origin.The average age of people found with an odontoma is 14, and the condition is frequently associated with an unerupted tooth..CLICK & SEE THE PICTURES

There are two types: compound and complex.

A compound odontoma still has the three separate dental tissues (enamel, dentin and cementum), but may present a lobulated appearance where there is no definitive demarcation of separate tissues between the individual “toothlets” (or denticles). It usually appears in the anterior maxilla.

The complex Odontoma is unrecognizable as dental tissues, usually presenting as a radioopaque area with varying densities. It usually appears in the posterior maxilla or in the mandible.

In 2011; 66% of odontogenic tumors are odontomas (University of Louisville School of Dentistry). 22% of odontogenic tumors are odontomas.

In July of 2014 in Mumbai, India, surgeons at Mumbai’s JJ Hospital removed 232 tooth-like growths from a complex odontoma growing in the lower jaw of 17 year old Ashik Gavai. This odontoma is proposed as “The World Record” to date.

Symptoms:

The most common symptoms are:Pain,Rash,Diarrea,Headache,Back pain,Constipation,Fever,Caugh,Runing nose,Vision change.

The list of signs and symptoms mentioned in various sources for Odontoma includes the 6 symptoms listed below:

*Dysphagia ( Dysphagia is difficulty in swallowing.There are about 194 causes of Dysphagia, including diseases and drug side effect causes.)
*Lump on gums
*Delayed tooth eruption (It is a condition in which there is a slow or late development of a tooth. There are about  60 causes of Delayed tooth eruption)
*Absent tooth
*Delayed primary tooth loss
*Increased bone size under tooth

Causes:
There are several causes of odontoma, some of them are :

*Dental conditions(Any condition that affects dental organs such as the teeth and gums. Examples of dental conditions include tooth decay, tooth infection, gingivitis, periodontitis, impacted tooth and canker sores)

*Oral conditions(Any condition affecting the mouth. Mouth conditions can affect any structure of the mouth such as teeth, gums, lips, tongue and cheeks. Conditions that can affect the mouth include candidiasis, oral cancer, stuttering, cleft palate, bad breath and gingivitis. )

*Head conditions(Any condition affecting the head. Some head conditions can be serious such as cancers and skull fractures whereas other conditions may be less threatening such as headaches and head lice)

*Benign tumors (A benign tumor is one that does not spread or “metastasize” to other parts of the body; a “malignant tumor” is one that does. A benign tumor is caused by cell overgrowth, and thus is different from a cyst or an abcess,)

Diagnosis:
Odontoma does not usually show external symptoms. These tumors are revealed when the x-rays are examined by the dentist. Although it is true that a delayed tooth or absent tooth may suggest there is a need for further examination.

The presence of an a tumor of dental origin requires further examination to determine what type of tumor it is before further action is taken. In addition, a histological diagnosis of the tissues that were extracted provides valuable information to the dentist.

No one really knows why an odontoma forms. The most likely reasons are trauma and/or infection at the site. Some dentists and researchers believe they are hereditary or they develop because of genetic mutations. One example of an inherited syndrome is known as Gardener Syndrome. It is responsible for a wide range of tumors in the body, including occasional odontoma.  When examined at the cellular level, all of the dental tissues are found, but in an abnormal combination.

Pulp, dentin, enamel and cementum may sometimes resemble a tooth like structure in a compound odontoma. These denticles are found in a surrounding supporting layer of fibrous cells. Since it is decalcified, the enamel looks like spaces around the tiny tooth structures.   Looking closer, you can see the calicified material either as a solid mass or as multiple, small tooth-like bodies visible by x-rays. Because it is easily separated from its bony location it can be distinguished from other possible tumors.

A complex odontoma has no specific sequence for all of the dental tissue. It does not resemble normal tooth structure. At the cellular level it appears as mostly tubular dentin that encloses hollow spaces. These circular spaces are decalcified but they once held enamel. On the edges there may be a thin layer of cementum which forms a capsule like tissue surrounding the mass.

Treatment :
The only real treatment of an these dental tumors is removal by surgery. An early discovery and treatment will be beneficial to the patient. It is a benign tumor made of dental tissue and it is a fairly simple extraction in most cases. A speedy recovery is generally expected.  Some complex tumors can result in complications after extraction. So it is essential to stay in contact with the dental surgeon.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Resources:
http://en.wikipedia.org/wiki/Odontoma
http://www.allhealthsite.com/odontoma.html
http://www.rightdiagnosis.com/o/odontoma/intro.

Salvia plebeia

Botanical Name : Salvia plebeia R. Brown
Family: Lamiaceae
Genus: Salvia
Species: S. plebeia
Kingdom: Plantae
Order: Lamiales
Scientific names :Salvia plebeia R. Brown ,Salvia brachiata Roxb. ,Salvia parviflora Roxb.
Common names:Mizo-kouiju (Japanese), Li zhi cao (Chin.),Sage weed (Engl.)

Habitat :Salvia plebeia is native to a wide region of Asia. It grows on hillsides, streamsides, and wet fields from sea level to 2,800 m (9,200 ft) As a weed in and about towns in various provinces at low altitudes.

Description:
Salvia plebeia is an annual, hairy herb. Stems are stout, erect, hoary, and 15 to 45 cms in height. Leaves are oblong ovate, 2.5 to 7.5 cms long, and narrowed and pointed at both ends. Spikes are panicled, often fastigiate. Flowers are hardly 6 mm long, lilac or nearly white, occurring in small, very numerous whorls in numerous, slender, panicled, glandular racemes. Calyx is stalked, bell-shaped, and 10 to 12 mm long; the upper calyx-lip is entire, and the lower one obtusely 2-toothed. Corolla-tube is very short, and the included upper lip is short, nearly straight, slightly flattened, and concave. Nutlets are very minute and ellipsoid.
CLICK & SEE THE PICTURES
You may click to see pictures of Salvia plebeia plant :
Constituents:
* Study yielded six compounds: hispidulin-glucoronide, hispidulin-7-O-D-glucoside, 6-methoxy-luteolin-7-glucoside, ß-sitosterol, 2′-hydroxy-5′-methoxybiochanin A and coniferyl aldehyde.

*Study of whole plant yielded: ß-sitosterol, hispidulin, carnosol, rosmadial, ursolic acid, pectolinarigenin, epirosmanol, caffeic acid methyl ester and scopoletin.

Edible Uses:  Flowers and leaves used as condiment.

Properties:-
*Considered astringent, diuretic, vermifuge.
*Antihepatotoxic, antidiarrheal, antispasmodic, analgesic.

Medicinal Uses:

Parts used: Seeds, leaves.

Folkloric
*Seeds are used in gonorrhea and menorrhage.
*In Bombay, used to increase sexual powers.
*In China, used as anti-inflammatory and for treating urinary tract infections.

Studies :-
• Antioxidant: Study yielded six compounds. (See:Constituents) Compounds 3, 4 and 5 ( 6-methoxy-luteolin-7-glucoside, ?-sitosterol, 2?-hydroxy-5?-methoxybiochanin A) showed strong antioxidant activities.
Pharmacologic Activities: Study on pharmacologic activities of Compound Salvia Plebeia Granules (CSPG) long used for treating UTIs showed a dose-related diuretic effect, antipyretic, antiblastic, and anti-inflammatory effects. Results support its folkloric use on treating urinary tract infections.
• Chemical Constituents: Study on whole plant of Salvia plebeia yielded nine compounds: ß-sitosterol, hispidulin, carnosol, rosmadial, ursolic acid, pectolinarigenin, epirosmanol, caffeic acid methyl ester and scopoletin. 8 and 9 were reported for Salvia genus for the first time and 3-7 from S. plebeia for the first time.
New Phenylfutanone Glucoside: Study yielded a new phenylbutanone glucoside, salviaplebeiaside, along with two known phenolic compounds, rosmarinic acid methyl ester and luteolin-7-O-ß-D-glucoside.
• Hepatoprotective: Study evaluated the hepatoprotective effects of “Chhit-Chan-Than,” a Taiwan herbal remedy believed to have anti-inflammatory and detoxification activities, and used in the treatment of hepatitis. The crude extracts of the three herbal components – Salvia plebeia, O gratissimum and O basilicum – were studied. Results showed that S. plebeia was the most potent of the three crude extracts, protecting the liver against CCl4-intoxication and D-GaIN-induced hepatotoxicity.

Disclaimer:
The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

Resources:
http://www.stuartxchange.com/SageWeed.html
http://en.wikipedia.org/wiki/Salvia_plebeia
http://www.britannica.com/EBchecked/topic/520091/Salvia
http://www.asianflora.com/Lamiaceae/Salvia-plebeia.htm

Use Chemical Peels to Get Rid off Wrinkles, Blemishes

Forget about the various creams available in the market that promise blemish-free and fair skin. If you really want soft, smooth and  flawless skin, chemical peels are the safest bet, say experts.

“A chemical peel is a treatment technique used to improve and smoothen the texture of facial skin using a chemical solution that causes the skin to blister and eventually peel off. The regenerated skin is usually smoother and less wrinkled than the old skin,” Anup Dhir, senior cosmetic surgeon at New Delhi‘s Apollo Hospital said.

Chemical peels stimulate the production of new cells, tighten and tone the skin, and decrease the appearance of fine lines and wrinkles. They also help in lightening acne scars.

“Peels treat wrinkled, blemished, unevenly pigmented or sun-damaged facial skin. Application of a chemical solution to improve the skin’s appearance leads to a controlled shedding of several layers of cells. This stimulus tightens the tissue collagen and brings about a fresh and vibrant appearance,” explains Mumbai-based cosmetic surgeon Meenakshi Agarwal.

Different types of chemical peels that one can opt for are alpha hydroxy acid peels (AHAs), beta hydroxy acid peels, retinoic acid peels, trichloroacetic acid peels and phenol peels that cater to regular maintenance of skin, acne and acne blemishes, anti aging, skin lightening, anti pigmentation and deep pigmentation among other problems.

“The choice of the most suitable chemical peel for an individual is determined by the patient’s skin texture, type, problems and many other similar aspects,” Dhir explained.

Kaya Skin Clinic’s medical head Snehal Sriram says chemical peels can also reduce or eliminate fine lines under the eyes and around the mouth.

“The procedure can treat wrinkles caused by sun damage and scarring as well as skin blemishes common with age and heredity. These peels can be performed on the face and neck, as well as body parts like chest, hands, arms, legs, underarms and back,” Sriram maintained.

The peels are also known as “lunch time procedures” since they only take between 20 to 40 minutes.

“The number of sittings required by an individual depends on the severity of the problems being addressed. Usually six to eight such peels are required at weekly or fortnightly intervals to get desired results,” said Dhir.

One important precaution after undergoing treatment is protection from exposure to sun.

“Ensure that you apply sunscreen in the right way, 15 minutes before going out in the sun and reapply after every three hours because after the peel you get a new, smooth skin that is sensitive to direct sunlight,” Agarwal explained.

These peels cost anywhere between Rs.1,000 and Rs.3,000($20 & $60) but one should consult a dermatologist before going for them.


Source:
The Times Of India

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Purple Sweet Potato Can Fight Cancer

A new breed of sweet potato is being touted as the superfood of the future, with experts saying the vegetable may stop people from getting cancer.
…………………...CLICK & SEE

The designer sweet potato, grown for its anti-cancer purple pigment, is also said to contain anti-aging and antioxidant chemicals, the Daily Telegraph reported.

Soyoung Lim, a researcher from Kansas State University, developed the variety of sweet potato with a purple skin and flesh to boost its cancer-fighting properties.

Lim said the colouring contained the chemical anthocyanin, which lowers the risk of cancer and could even slow down some types of the disease. Scientists have found anthocyanin slows down the growth of cancerous cells in colon cancer.

Source:
The Times Of India

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Broccoli ‘May Help Protect Lungs’

numbered version of :Image:Respiratory system ...Image via Wikipedia

 

A substance found in broccoli may limit the damage which leads to serious lung disease, research suggests.
…….CLICK & SEE

Sulforapane is found in broccoli and brussel sprouts

Chronic obstructive pulmonary disease (COPD) is often caused by smoking and kills about 30,000 UK residents a year.

US scientists found that sulforapane increases the activity of the NRF2 gene in human lung cells which protects cells from damage caused by toxins.

The same broccoli compound was recently found to be protective against damage to blood vessels caused by diabetes.

Brassica vegetables such as broccoli have also been linked to a lower risk of heart attacks and strokes.

Cell pollutants

In the latest study, a team from Johns Hopkins School of Medicine found significantly lower activity of the NRF2 gene in smokers with advanced COPD.

Writing in the American Journal of Respiratory and Critical Care Medicine, they said the gene is responsible for turning on several mechanisms for removing toxins and pollutants which can damage cells.

“We know broccoli naturally contains important compounds but studies so far have taken place in the test tube and further research is needed to find if you can produce the same effect in humans” :-Spokeswoman, British Lung Foundation

Previous studies in mice had shown that disrupting the NRF2 gene caused early onset severe emphysema – one of the conditions suffered by COPD patients.

Increasing the activity of NRF2 may lead to useful treatments for preventing the progression of COPD, the researchers said.

In the study, they showed that sulforapane was able to restore reduced levels of NRF2 in cells exposed to cigarette smoke.

“Future studies should target NRF2 as a novel strategy to increase antioxidant protection in the lungs and test its ability to improve lung function in people with COPD,” said study leader Dr Shyam Biswal.

A spokeswoman for the British Lung Foundation said: “This is an important study for the 3 million people in the UK with COPD because of its findings about the imbalance of oxidants and antioxidants in the lungs.

“We know broccoli naturally contains important compounds but studies so far have taken place in the test tube and further research is needed to find if you can produce the same effect in humans.

Sources:BBC NEWS:Sept 12. ’08

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