News on Health & Science

Agents that regulates appetite identified

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Scientists in Japan have identified a molecule responsible for making mammals feel full, a discovery that could lead to new ways to treat obesity in humans.

Scientists believe appetite is controlled in a region of the brain called the hypothalamus, and the group of researchers claims to be the first to pinpoint an agent that triggers an increase or decrease in appetite.

In an article published on Sunday in the online version of the journal Nature, the scientists identified the molecule as nesfatin-1, which is produced naturally in the brain.

After injecting the molecule into the brains of rats, the scientists observed that the rodents began to eat less and lose weight.

The researchers also were able to induce the rats to eat more, by blocking nesfatin-1

After we injected anti-nesfatin-1 antibody, these rats showed increased appetite and finally showed a progressive increase in body weight,” Masatomo Mori of the medicine and molecular science department at Gunma University Graduate School of Medicine told Reuters in a telephone interview.

Mori said the finding could pave the way for treating obesity, which has become a major health problem in the developing world as well as in economically advanced countries.

There are at least a billion overweight adults across the world, 300 million of them considered obese, according to the World Health Organization.

Obesity has been linked to chronic diseases, such as type 2 diabetes, cardiovascular disease, hypertension and stroke, and some forms of cancer.

In a separate study, it has been found that the hormone leptin could help keep the body from producing too much insulin, according to a study in mice with type 2 diabetes.

People with type 2 diabetes often become resistant to the effects of insulin, causing to much of it to build up in the body.

Reporting in the September issue of the journal Peptides, researchers from the University of Florida injected a gene into the brains of diabetic mice, hoping to increase the production of the appetite-controlling hormone leptin in the hypothalamus.

Insulin levels in mice that received gene therapy returned to normal — even when they were fed a high-fat diet, the
researchers found. High-fat diets typically help trigger or worsen type 2 diabetes.

Mice that ate a high-fat diet but did not receive gene therapy, however, continued to overproduce insulin and have high blood-sugar levels.

“This was totally unexpected. Until now, there way no evidence that leptin action in the hypothalamus had control on insulin secretion.

With leptin gene therapy, we can re-impose that control,” senior author Satya Kalra, a University of Florida, Gainesville, professor of neuroscience, said.

(As published in the Times Of India)

Ailmemts & Remedies


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Piles (Haemorrhoids) are enlarged, painful veins in the rectum. They are also known as hemorrhoids. It is a condition in which inflammation takes place in the veins around the anus or lower rectum. Piles can be internal or external. External piles are painful, but do not involve much of bleeding. On the contrary, internal piles witness the release of dark blood. It is an ailment that has become very common in todays society….click & see

Haemorrhoids are very common. They are said to be more common in countries where the diet has traditionally been more processed and low in fibre. The main contributory causes are those things that cause us to raise the pressure in the abdomen. This causes the blood vessels to swell and become engorged.

click & see the pictures

Irritation while passing stools, Bleeding, Itching and pain in the rectum region, wind formation in the stomach and sitting becomes a problem.

Most common causes:

Heredity, Pregnancy, Obesity, Chronic constipation, Strainus work, Aging, Bowel disorder(IBS),prolonged periods of sitting and standing , mental tension, and sometimes Anal intercourse.

It seems that the people most at risk of developing haemorrhoids are those who have more causes for raised abdominal pressure


It is usually best, with haemorrhoids, to get by with the least treatment possible, as even after the most extensive treatments they may still return.

  • Many times they will settle down over a matter of days without any treatment.
  • Cream or suppositories (bullet-shaped tablets to be inserted into the anus) may be bought over the counter, or your doctor may prescribe one. These soothe itching and pain, and cause swelling and bleeding to diminish.
  • Cold compresses, even ice can be helpful.

If you do not get better with these approaches, your doctor may ask a specialist to see you who may:

  • Put little rubber bands round the haemorrhoids, which will cause them to shrivel and wither away.
  • Inject a substance into the haemorrhoids which causes them to wither away (sclerotherapy).
  • Cut away the problem, usually under a general anaesthetic.

Some Ayurvedic Home Remedies:

  • Radish juice should be taken twice a day, once in the morning and then later in the night. Initially drink about ¼ cup of radish juice and then gradually increase it to ½ cup.
  • Soak 3-4 figs in a glass of water. Keep it overnight. Consume the figs on an empty stomach, the next day in the morning.
  • Roast 1 tsp of black cumin seeds and mix with 1 tsp of unroasted black cumin seeds and powder them together. Consume a half tsp of this powder with a glass of water, once in a day.
  • Prevention: Haemorrhoids are very common, and will occur anyway, but, as implied above, useful aspects of prevention are:
  • Avoid becoming overweight, and lose weight if you are obase.
  • Eat a high fibre diet.
  • Exercise regularly.
  • Herbs: Haritaki (Terminalia chebula), Jimikand (Amorphophallus campanulatus)
  • Ayurvedic Supplements: 1.Arshoqhani Bati, 2.Pirrhoids Tablets and Adhyaristha……….( Click to buy)
  • Diet: Avoid : potato, yellow variety of pumpkin and colocasia.
  • Eat the following : Mango seeds, fresh seasame seeds, Jambuli fruit,Dry fig, Papaya and Amlaki, Radish, Turnip,Bitter groud, Onion, Ginger grains, Rice and Wheat.
  • Life Style: Regular Exercise, Intestine should always be thoroughly cleaned, Do not indulge in sex in excess, Avoid horse riding or sitting on hard seat and dring lots of water.

YOGA Exercise : Cobra (Bhujang Asana) and Bow (Dhanur Asana)

Ayurvedic Massaging Oil: Kasidadi Taila.

Homeopathic medication for piles (Haemorrhoids) may sometimes works well

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.

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