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Brain’s Role in Autism Probed

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A psychology researcher has pinpointed regions of the brain that are linked to “ritualistic repetitive behavior” in autistic children — the insatiable desire to rock back and forth for hours or to tirelessly march in place.

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Keith Shafritz, an assistant professor of psychology at Hofstra University on Long Island, compared brain images of autistic children with those of neurologically normal youngsters. He and collaborators at Duke University and the University of North Carolina in Chapel Hill used a form of magnetic resonance imaging to explore sites in the brain.

They reported their findings in the current issue of Biological Psychiatry.

Repetitive behavior is one of autism’s core traits. It has driven parents to extremes as they try to distract a child to engage in other activities.

Mapping the brain constitutes a journey into the inner labyrinths of a three-pound cosmos where countless frontiers have yet to be explored.

In children with autism, Shafritz found deficits in specific regions of the cerebral cortex, the outer layer of gray matter linked to all higher human functions, including repetitive behavior. He also mapped deficits in the basal ganglia, a region deep below the cerebral hemispheres.

“We like to think about the research process as discovering clues why people engage in certain behaviors,” Shafritz said. “We were able to identify a series of brain regions that showed diminished activity when people were asked to alter certain behaviors and were not able to do so.”

Autism is a neurodevelopmental disorder that is becoming a major public policy issue. Federal health officials estimate that it afflicts 1 in every 150 children, which affects not only families but communities.

School systems don’t have enough appropriately trained teachers. Social services departments are overwhelmed by parents who need support and respite care.

For clues to the disorder, some scientists are scanning the human genome for suspect DNA.

Others, like Shafritz, are exploring the geography of the brain.

Edward G. Carr, a psychology professor at Stony Brook University in New York, said Shafritz’s discovery was important because it helped demystify repetitive behavior.

“Repetitive behavior is sometimes called self-stimulatory behavior. A very common form of it is body-rocking. A child will do it for hours,” Carr said. “Another child may wave his or her hands back and forth in front of their eyes. This is very common, and it’s called hand-flapping. They extend their arms forward and wave their hands in front of them. It’s like a light show.”

Shafritz said the brain areas associated with repetitious behavior were not associated with another autism problem, self-injury. Some children repeatedly slam their heads against a wall, for instance.

Still, Shafritz found a relationship between the newly identified brain areas and overlapping regions linked to schizophrenia, obsessive compulsive disorder and attention-deficit hyperactivity disorder.

Dr. Anil K. Malhotra, director of psychiatric research at Zucker Hillside Hospital in Glen Oaks, N.Y., said he was not surprised. He too is studying links between autism and schizophrenia, and autism and obsessive-compulsive disorder.

Sources:Los Angles Times

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Ailmemts & Remedies

Claustrophobia

Definition:
A phobia is a form of anxiety disorder in which someone has an intense and irrational fear of certain objects or situations. Anyone suffering from high levels of anxiety is at risk of developing a phobia. One of the most common phobias is claustrophobia, or the fear of enclosed spaces. A person who has claustrophobia may panic when inside a lift, aeroplane, crowded room or other confined area.

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Some other phobias, borne from anxiety, include social phobia – fear of embarrassing yourself in front of others – and agoraphobia, which is the fear of open spaces. The cause of anxiety disorders such as phobias is thought to be a combination of genetic vulnerability and life experience. With appropriate treatment, it is possible to overcome claustrophobia or any other phobia.

It is an anxiety disorder that involves the fear of enclosed or confined spaces. Claustrophobes may suffer from panic attacks, or fear of having a panic attack, in situations such as being in elevators, trains, or aircraft.

Conversely, people who are prone to having panic attacks will often develop claustrophobia.[citation needed] If a panic attack occurs while they are in a confined space, then the claustrophobe fears not being able to escape the situation. Those suffering from claustrophobia might find it difficult to breathe in enclosed spaces. Like many other disorders, claustrophobia can sometimes develop due to a traumatic incident in childhood.

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Claustrophobia can be treated in similar ways to other anxiety disorders, with a range of treatments including cognitive behavior therapy and the use of anti-anxiety medication. Hypnosis is an alternative treatment for claustrophobia.

The name claustrophobia comes from the Latin word claustrum which means “a bolt, a place shut in” and the Greek word phobos meaning “fear”.


Causes :-

Claustrophobia can develop from either a traumatic childhood experience (such as being trapped in a small space during a childhood game), or from another unpleasant experience later on in life involving confined spaces (such as being stuck in an elevator).

When an individual experiences such an event, it can often trigger a panic attack; this response then becomes programmed in the brain, establishing an association between being in a tight space and feeling anxious or out-of-control. As a result, the person often develops claustrophobia.

Symptoms:
If a person suffering from claustrophobia suddenly finds themselves in an enclosed space, they may have an anxiety attack. Symptoms can include:

*Sweating
*Accelerated heart rate
*Hyperventilation, or ‘overbreathing’
*Shaking
*Light-headedness
*Nausea
*Fainting
*Fear of actual harm or illness.

Specific symptoms of claustrophobia:-
When in an enclosed space, the signs of claustrophobia may include:

  • Inside a room – automatically checking for the exits, standing near the exits or feeling alarmed when all doors are closed.
  • Inside a vehicle, such as a car – avoiding times when traffic is known to be heavy.
  • Inside a building – preferring to take the stairs rather than the lift, and not because of health reasons.
  • At a party – standing near the door in a crowded room, even if the room is large and spacious.
  • In extreme cases – for a person with severe claustrophobia, a closed door will trigger feelings of panic.

The catch-22 of avoidance
Once a person has experienced a number of anxiety attacks, they become increasingly afraid of experiencing another. They start to avoid the objects or situations that bring on the attack. However, any coping technique that relies on avoidance can only make the phobia worse. It seems that anticipating the possibility of confinement within a small space intensifies the feelings of anxiety and fear.

Frequency:-
It was found that 5-10.6% of people screened before an MRI scan had claustrophobia. Furthermore, it was found that 7% of patients had unidentified claustrophobia, and had to terminate the scanning procedure prematurely. 30% reported milder distress due to the necessity to lie in a confined space for a long time. For specific phobias in general, there is a lifetime prevalence rate of 7.2%-11.3%. Other forms of Claustrophobia include conditions such as Agrophobia and panic attacks.

The thought of treatment can be frightening
For someone with a disabling phobia, the realisation that this fear is irrational and that treatment is needed can cause further anxiety. Since most treatment options depend on confronting the feared situation or object, the person may feel reluctant.

Support and encouragement from family and friends is crucial. A person trying to overcome a phobia may find some treatment methods particularly challenging and will need the love and understanding of their support people. The therapist may even ask the family members or friends to attend certain sessions, in order to bolster the courage of the person seeking treatment.

Treatment:-

There is no cure for claustrophobia, however, there are several forms of treatment that can help an individual control her condition. Treatment for claustrophobia can include behavior therapy, exposure therapy, drugs or a combination of several treatments.
Treating phobias, including claustrophobia, relies on psychological methods. Depending on the person, some of these methods may include:

  • Flooding – this is a form of exposure treatment, where the person is exposed to their phobic trigger until the anxiety attack passes. The realisation that they have encountered their most dreaded object or situation, and come to no actual harm, can be a powerful form of therapy.
  • Counter-conditioning – if the person is far too fearful to attempt flooding, then counter-conditioning can be an option. The person is taught to use specific relaxation and visualisation techniques when experiencing phobia-related anxiety. The phobic trigger is slowly introduced, step-by-step, while the person concentrates on attaining physical and mental relaxation. Eventually, they can confront the source of their fear without feeling anxious. This is known as systematic desensitisation.
  • Modelling – the person watches other people confront the phobic trigger without fear and is encouraged to imitate that confidence.
  • Cognitive behaviour therapy (CBT) – the person is encouraged to confront and change the specific thoughts and attitudes that lead to feelings of fear.
  • Medications – such as tranquillisers and antidepressants. Drugs known as beta blockers may be used to treat the physical symptoms of anxiety, such as a pounding heart.

Alternative claustrophobia treatments include regression hypnotherapy, in which hypnotherapy is used to remember the traumatic event that led to the individual’s claustrophobia. The patient is taught to see the event with ‘adult’ eyes, which helps to decrease the sense of panic that it has instilled into their minds.

Length of treatment
The person may be treated as an outpatient or, sometimes, as an inpatient if their phobia is particularly severe. Generally, treatment consists of around eight to 10 weeks of bi-weekly sessions.

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Click to learn about :->Open MRI reduces patient claustrophobia, study confirms

Anxiety Disorder Treatment

Where to get help

  • Sane Australia Helpline Tel. 1800 187 263
  • Your doctor
  • Psychologist
  • Psychiatrist
  • Trained therapist

Things to remember

  • A phobia is an intense and irrational fear of certain objects or situations.
  • A person who has claustrophobia may panic when inside an enclosed space, such as a lift, aeroplane or crowded room.
  • With appropriate treatment, it is possible to overcome claustrophobia or any other phobia.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Resources:
http://www.betterhealth.vic.gov.au/bhcv2/bhcarticles.nsf/pages/Claustrophobia?open
http://en.wikipedia.org/wiki/Claustrophobia
http://www.epigee.org/mental_health/claustrophobia.html

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