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Kava

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Botanical Name: Piper methysticum
Family:Pepper/ Piperaceae
Kingdom: Plantae
Order: Piperales
Genus: Piper
Species: P. methysticum
Other names: kava kava, kawa, kew, yagona, sakau .awa (Hawaii), ‘ava (Samoa), yaqona (Fiji), and sakau (Pohnpei).
Parts Used:The part of the plant used medicinally is the root. Although the root was traditionally chewed or made into a beverage, kava is now available in capsule, tablet, beverage, tea, and liquid extract forms.

Habitat:South Pacific Isands.

Description:
Kava is a tall shrub in the pepper family that grows in the South Pacific islands.Kava kava belongs to the pepper family (Piperaceae) and is also known as kava, asava pepper, or intoxicating pepper. It grows to an average height of 6 ft (1.83 m) and has large heart-shaped leaves that can grow to 10 in (25.4 cm) wide. A related species is Piper sanctum, a native plant of Mexico that is used as a stimulant. It has been used there for thousands of years as a folk remedy and as a social and ceremonial beverage.

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The part of the plant used medicinally is the root. Although the root was traditionally chewed or made into a beverage, kava is now available in capsule, tablet, beverage, tea, and liquid extract forms.

Botany and agronomy
There are several cultivars of kava, with varying concentrations of primary and secondary psychoactive substances. The largest number are grown in the Republic of Vanuatu, and so it is recognised as the “home” of kava. Kava was historically grown only in the Pacific islands of Hawaii, Federated States of Micronesia, Vanuatu, Fiji, the Samoas and Tonga. Some is grown in the Solomon Islands since World War II, but most is imported. Kava is a cash crop in Vanuatu and Fiji.

The kava shrub thrives in loose, well-drained soils where plenty of air reaches the roots. It grows naturally where rainfall is plentiful (over 2,000 mm/yr). Ideal growing conditions are 20 to 35 degrees Celsius (70 to 95 °F), and 70–100% relative humidity. Too much sunlight is harmful, especially in early growth, so kava is an understory crop.

Kava cannot reproduce sexually. Female flowers are especially rare and do not produce fruit even when hand-pollinated. Its propagation is entirely due to human efforts by the method of striking.

Traditionally, plants are harvested around 4 years of age, as older plants have higher concentrations of kavalactones. But in the past two decades farmers have been harvesting younger and younger plants, as young as 18 months. After reaching about 2 m height, plants grow a wider stalk and additional stalks, but not much taller. The roots can reach 60 cm depth.

Composition
Fresh kava root contains on average 80% water. Dried root contains approximately 43% starch, 20% fibers, 15% kavalactones, 12% water, 3.2% sugars, 3.6% proteins, and 3.2% minerals. Kavalactone content is greatest in the roots and decreases higher up the plant. Relative concentrations of 15%, 10% and 5% have been observed in the root, stump, and basal stems, respectively.

The mature roots of the kava plant are harvested after a minimum of 4 years (at least five years ideally) for peak kavalactone content. Most kava plants produce around 50 kgs (110 lbs) of root when they are harvested. Kava root is classified into two categories: crown root (or chips) and lateral root. Crown roots are the large diameter pieces that look like big (1.5 inch to 5 inches diameter) wooden poker chips. Most kava plants consist of approximately 80% crown root upon harvesting. Lateral roots are smaller diameter roots that look more like a typical root. A mature kava plant is approximately 20% lateral roots. Kava lateral roots have the highest content of kavalactones in the kava plant. “Waka” grade kava is kava that is made of lateral roots only.
General use
Kava kava has been prescribed by healthcare providers to treat a wide range of ailments, including insomnia, nervousness, and stress-related anxiety and anxiety disorders. It is also reported to relieve urinary infections, vaginitis, fatigue, asthma, rheumatism, and pain.

The active ingredients in kava kava are called kavalactones and are found in the root of the plant. Kavalactones cause reactions in the brain similar to pharmaceutical drugs prescribed for depression and anxiety. Research has shown that kavalactones have a calming, sedative effect that relaxes muscles, relieves spasms, and prevents convulsions. Kavalactones also have analgesic (pain-relieving) properties that may bring relief to sore throats, sore gums, canker sores, and toothaches.

Kava kava is a strong diuretic that is reportedly beneficial in the treatment of gout, rheumatism, and arthritis. The diuretic effect of the herb relieves pain and helps remove waste products from the afflicted joints. Antispasmodic properties have shown to help ease menstrual cramps by relaxing the muscles of the uterus. Kava kava’s antiseptic and anti-inflammatory agents may help relieve an irritable bladder, urinary tract infections, and inflammation of the prostate gland.

Kava root...……………….....Kava root power…………….Cava in bottle as medicine

Medicinal Uses:
Kava kava has been used as a medicinal herb for hundreds of years and used by Pacific Islanders to treat rheumatism, asthma, worms, obesity, headaches, fungal infections,leprosy, gonorrhea, vaginal infections, urinary infections, menstrual problems, migraine headaches, and insomnia. It was also used as a diuretic, an aphrodisiac, to promote energy, and to bring about sweating during colds and fevers. Pacific Islanders consume a kava kava drink at social, ritual, and ceremonial functions. It is drunk at ceremonies to commemorate marriages, births, and deaths; in meetings of village elders; as an offering to the gods; to cure illness; and to welcome honored guests. Pope John Paul II, Queen Elizabeth II, and Hillary Rodham Clinton have all drunk kava kava during their island visits.

The drink is prepared by grinding, grating, or pounding the roots of the plant, then soaking the pulp in cold water or coconut milk. Traditionally the root was chewed, spit into a bowl, and mixed with coconut milk or water. That practice is no longer the standard.

Captain James Cook has been credited with the Western discovery of kava kava during his journey to the South Pacific in the late 1700s. The first herbal products made from kava kava appeared in Europe in the 1860s. Pharmaceutical preparations became available in Germany in the 1920s. Currently, kava kava has received widespread attention because of its reputation to promote relaxation and reduce stress.

Preparation & Consumption:
Traditional preparation
Kava is consumed in various ways throughout the Pacific Ocean cultures of Polynesia, Vanuatu, Melanesia and some parts of Micronesia and Australia. Traditionally it is prepared by either chewing, grinding or pounding the roots of the kava plant. Grinding is done by hand against a cone-shaped block of dead coral; the hand forms a mortar and the coral a pestle. The ground root/bark is combined with only a little water, as the fresh root releases moisture during grinding. Pounding is done in a large stone with a small log. The product is then added to cold water and consumed as quickly as possible.

Kava root drying in Lovoni village, Ovalau

The extract is an emulsion of kavalactone droplets in starch. The taste is slightly pungent, while the distinctive aroma depends on whether it was prepared from dry or fresh plant, and on the variety. The colour is grey to tan to opaque greenish.

Kava prepared as described above is much more potent than processed kava. Chewing produces the strongest effect because it produces the finest particles. Fresh, undried kava produces a stronger beverage than dry kava. The strength also depends on the species and techniques of cultivation. Many find mixing powdered kava with hot water makes the drink stronger. However the active ingredients of kava, such as Kavalactone, are ruined at 140 degrees. Most tea steeps at 180 degrees for at least a couple minutes which will reduce the potency of the kava.

In Vanuatu, a strong kava drink is normally followed by a hot meal or tea. The meal traditionally follows some time after the drink so that the psychoactives are absorbed into the bloodstream quicker. Traditionally no flavoring is added.

Fijians commonly share a drink called “grog”, made by pounding sun-dried kava root into a fine powder and mixing it with cold water. Traditionally, grog is drunk from the shorn half-shell of a coconut, called a “bilo.” Despite tasting very much like dirty water, grog is very popular in Fiji, especially among young men, and often brings people together for storytelling and socializing.

Modern preparation
In modernized countries Kava beverage is usually made from Kava root powder. The root is dried and then finely ground into powder before being exported. Generally one tablespoon of powder is added per cup of water, but sometimes as much as a half a cup of powder (eight tablespoons) is added per cup of water to increase potency. The powder is then soaked in water for approximately 30 minutes to allow the water to completely soak through the powdered fibers. Lecithin is often added to aid in the process of emulsifying the kavalactones with water. The Kava powder, water, and lecithin are blended in a blender for several minutes then strained into a straining cloth. Nylon, cheesecloth, and silk screen are common materials for straining. The remaining liquid is squeezed from the pulp and the pulp is discarded. As an alternative to the blender method, with the powdered pulp enclosed within the straining material, the pulp is massaged for five to ten minutes in water, then the liquid is wrung out. The more pressure that is applied to the wet powdered pulp while wringing it out, the more kavalactones will be released from it. Finally the pulp resin is discarded and the beverage is enjoyed. Often coconut water, coconut milk, lemongrass, cocoa, sugar, or soy milk is added to improve flavor.

Pharmacology
Kava’s active principal ingredients are the kavalactones, of which at least 15 have been identified and are all considered psychoactive. Only six of them produce noticeable effects, and their concentrations in kava plants vary. Different ratios can produce different effects. Kava has some abuse potential and some experts recommend cycling use over 1 to 3 months.

Pills
Pharmaceutical companies and herbal supplement companies extract kavalactones from the kava plant using solvents such as acetone and ethanol and produce pills standardized with between 30% and 90% kavalactones. Some kava herbal supplements have been accused of contributing to very rare but severe hepatotoxic reactions (see section on safety) such may have been due to the use of plant parts other than the root, such as stems or peelings that are known to have been exported to European manufacturers. A kava pill usually has anywhere from 60 mg to 150 mg of kavalactones. By comparison the typical bowl of traditionally prepared kava beverage has around 250 mg of kavalactones.

Uses: In some parts of the Western World, kava extract is marketed as herbal medicine against stress, insomnia, and anxiety. A Cochrane Collaboration systematic review of its evidence concluded that it was likely to be more effective than placebo at treating short-term social anxiety. Safety concerns have been raised over liver toxicity, although research indicates that this may be largely due to the use of stems and leaves in supplements, which were not used indigeneously

The word kava is used to refer both to the plant and the beverage produced from its roots. Kava is a tranquilizer primarily consumed to relax without disrupting mental clarity. Its active ingredients are called kavalactones.

Because kava can cause sedation, and in high amounts, intoxication, kava drinks are consumed in some parts of the world in much the same way as alcohol.

Although it’s not clear exactly how kava works, kavalactones may affect the levels of neurotransmitters (chemicals that carry messages from nerve cells to other cells) in the blood. Kava has been found to affect the levels of specific neurotransmitters, including norepinephrine, gamma aminobutyric acid (GABA) and dopamine

A number of well-designed studies have examined kava’s ability to relieve anxiety compared to anxiety medication or a placebo. The results have been promising.

In 2003, a review by the Cochrane Collaboration examined the existing research to see how kava fared compared to a placebo in treating anxiety. After analyzing the 11 studies (involving a total of 645 people) that met the criteria, the researchers concluded that kava “appears to be an effective symptomatic treatment option for anxiety.” However, they added that it seemed to be a small effect.

Effects:
A moderately potent kava drink causes effects within 20–30 minutes that last for about two and a half hours, but can be felt for up to eight hours. Because of this, it is recommended to space out servings about fifteen minutes apart. Some report longer term effects up to two days after ingestion, including mental clarity, patience, and an ease of acceptance. The effects of kava are most often compared to alcohol, or a large dose of Valium.

The sensations, in order of appearance, are slight tongue and lip numbing (the lips and skin surrounding may appear unusually pale); mildly talkative and sociable behavior; clear thinking; anxiolytic (calming) effects; relaxed muscles; and a very euphoric sense of well-being. The numbing of the mouth is caused by the two kavalactones kavain and dihydrokavain which cause the contraction of the blood vessels in these areas acting as a local topical anesthetic. These anesthetics can also make one’s stomach feel numb. Sometimes this feeling has been mistaken for nausea. Some report that caffeine, consumed in moderation in conjunction with kava can significantly increase mental alertness.

A potent drink results in a faster onset with a lack of stimulation, the user’s eyes become sensitive to light, they soon become somnolent and then have deep, dreamless sleep within 30 minutes. Sleep is often restful and there are pronounced periods of sleepiness correlating to the amount and potency of kava consumed. Unlike alcohol-induced sleep, after wakening the drinker does not experience any mental or physical after effects. However, this sleep has been reported as extremely restful and the user often wakes up more stimulated than he or she normally would. Although excessive consumption of exceptionally potent brew has been known to cause pronounced sleepiness into the next day. Although heavy doses can cause deep dreamless sleep, it is reported that many people experience lighter sleep and rather vivid dreams after drinking moderate amounts of kava.

After thousands of years of use by the Polynesians and decades of research in Europe and the U.S., the traditional use of kava root has never been found to have any addictive or permanent adverse effects. Users do not develop a tolerance. While small doses of kava have been shown to slightly improve memory and cognition, large amounts at one time have been shown to cause intoxication. In Utah, California, and Hawaii there have been cases where people were charged with driving under the influence of alcohol after drinking a significant amount of kava (eight cups or more) although some of them were acquitted due to the laws not being broad enough to cover kava consumption.

Kava Culture:
Kava is used for medicinal, religious, political, cultural and social purposes throughout the Pacific. These cultures have a great respect for the plant and place a high importance on it. Correspondingly, the paraphernalia surrounding the traditional kava ceremony are expertly crafted. Traditionally designed kava bowls are bowls made from a single piece of wood, with multiple legs. More modern examples are also highly decorated, often carved and inlayed with mother of pearl and shell.CLICK & SEE

Kava root being prepared in Asanvari, a village on Maewo Island in the Pacific nation of Vanuatu. Photo taken in September, 2002 by Jordan Bigel.

Kava is used primarily at social gatherings to increase amiability and to relax after work. It has great religious significance, being used to obtain inspiration. Among some fundamentalist Christian sects in the Western Pacific, the drink has been demonized and seen as a vice, and young members of these religions often reject its traditional use. However, among most mainline Christian denominations, i.e. the Roman Catholic, Methodist, and Anglican churches, kava drinking is encouraged where it replaces the greater danger of alcohol.

Basic research on anti-cancer potential
On 15 February 2006, the Fiji Times and Fiji Live reported that researchers at the University of Aberdeen in Scotland and the Laboratoire de Biologie Moleculaire du Cancer in Luxembourg had discovered that kava may treat ovarian cancer and leukemia. Kava compounds inhibited the activation of a nuclear factor that led to the growth of cancer cells. The Aberdeen University researchers published in the journal The South Pacific Journal of Natural Science that kava methanol extracts had been shown to kill leukemia and ovarian cancer cells in test tubes.The kava compounds were shown to target only cancerous cells; no healthy cells were harmed. This may help explain why kava consumption is correlated with decreased incidence of cancer.

Fiji Kava Council Chairman Ratu Josateki Nawalowalo welcomed the findings, saying that they would boost the kava industry. For his part, Agriculture Minister Ilaitia Tuisese called on the researchers to help persuade members of European Union to lift their ban on kava imports.

Liver damage incidents and regulation
In 2001 concerns were raised about the safety of commercial kava products. There have been allegations of severe liver toxicity, including liver failure in some people who had used dietary supplements containing kava extract (but not in anyone who had drunk kava the traditional way). Out of the 50 people worldwide taking kava pills and extracts that have had some type of problem, almost all of them had been mixing them with alcohol and pills that could have effects on the liver.[16] The fact that different kava strains have slightly different chemical composition made testing for toxicity difficult as well.

The possibility of liver damage consequently prompted action of many regulatory agencies in European countries where the legal precautionary principle so mandated. In the UK, the Medicines for Human Use (Kava-kava) (Prohibition) Order 2002 prohibits the sale, supply or import of most derivative medicinal products. Kava is banned in Switzerland, France, Germany and The Netherlands[17]. The health agency of Canada issued a stop-sale order for kava in 2002. But legislation in 2004 made the legal status of kava uncertain. The United States CDC has released a report[18] expressing reservations about the use of kava and its possibly adverse side effects (specifically severe liver toxicity), as has the Food and Drug Administration (FDA). The Australian Therapeutic Goods Administration has recommended that no more than 250 mg of kavalactones be taken in a 24 hour period.[20] According to the Medicines Control Agency in the U.K., there is no safe dose of kava, as there is no way to predict which individuals would have adverse reactions.

Potential Side Effects of Kava:
Side effects include indigestion, mouth numbness, skin rash, headache, drowsiness and visual disturbances. Chronic or heavy use of kava has linked to pulmonary hypertension, skin scaling, loss of muscle control, kidney damage, and blood abnormalities.

Kava may lower blood pressure and it also may interfere with blood clotting, so it shouldn’t be used by people with bleeding disorders. People with Parkinson’s disease shouldn’t use kava because it may worsen symptoms.

Kava should not be taken within 2 weeks of surgery. Pregnant and nursing women, children, and people with liver or kidney disease shouldn’t use kava.

Possible Drug Interactions:
Kava shouldn’t be taken by people who are taking Parkinson’s disease medications, antipsychotic drugs, or any medication that influences dopamine levels.

Kava shouldn’t be combined with alcohol or medications for anxiety or insomnia, including benzodiazepines such as Valium (diazepam) or Ativan (lorazepam). It may have an additive effect if taken with drugs that cause drowsiness.

Kava may have an additive effect if combined with antidepressant drugs called monoamine oxidase inhibitors (MAOI).

Kava shouldn’t be taken with any drug or herb that impairs liver function. Kava also may interfere with blood clotting, so people taking Coumadin (warfarin) or any drug that influences blood clotting should avoid it unless under a doctor’s supervision.

Kava is a diuretic, so it may have an additive effect if combined with drugs or herbs that have diuretic properties.

Allergy
Literature suggests that <0.5% of people that take kava have an allergic reaction to it. Allergic reactions are usually mild and include itchy skin or itchy throat, and hives on the skin usually prevalent on the user’s belly region. If someone has an allergy to any relative of the pepper family, such as black pepper, they have a higher chance of having a kava allergy.

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Disclaimer:The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

Resources:
http://altmedicine.about.com/od/kava/p/kava.htm
http://en.wikipedia.org/wiki/Kava

http://www.healthline.com/galecontent/kava-kava

 

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