Tag Archives: Vitamin B6

Too Much Worse Than too Little?

We live in a stressful world, with family, work, financial needs, health, pollution, lack of sleep, and the new urban life style taking their toll. Fighting stress has become a money spinner. Doctors advocate preventive methods like diet, exercise, yoga, meditation, holidays and hobbies. These remedial measures require time and effort, scarce commodities in the 21st century. Media publicity highlights the potential hazards of stress. This has resulted in health being slickly packaged as a profitable commodity. Nutritional supplements (consumed dissolved in milk or water) and vitamins, once used for the sick, bedridden or elderly are now considered essential “stress busters”.

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Pharmaceutical companies vie with one another with tall claims, marketing gimmicks and eye-catching advertisements for formulations and supplements. They emphasise rejuvenation, prevention of disease, and accelerated mental development. After all everyone wants their child to be a “topper” or the next Sachin Tendulkar.

Vitamin supplements can be purchased over the counter (OTC) or prescribed. It pays to be knowledgeable about what is actually required, especially if you consult more than one physician each of whom may add a supplement. Some “high potency” vitamin supplements provide one ingredient in high concentrations and the rest in sub optimal doses. If you are taking one or more tablets or capsules of B complex, a vitamin and mineral supplement, additional calcium and a fortified beverage, the total concentration of one or more ingredients may be more than you require.

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There may also be mutual antagonism among the ingredients, preventing absorption and utilisation. Also, if the instructions says “once a day,” don’t take it twice; you will be doing yourself more harm than good.

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The fat soluble vitamins A,D, K and E are stored in body fat and the liver. Stores of A and D can last as long as six months. They can accumulate to toxic levels if consistently consumed in excess. Vitamin A occurs naturally as carotenoids in yellow foods. Excessive consumption of carotenoids can cause a yellow discolouration of the skin. Unnecessary consumption of supplements can result in hypervitaminosis A. In children it causes symptoms similar to that of a brain tumour.

Retinoids, the precursor of vitamin A, are administered as a treatment for acne. In a pregnant woman this can cause severe congenital malformations.
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Vitamin D prevents rickets. Inadvertent administration of too much causes floppy muscles, irritability, vomiting, calcification in various body parts, aortic valve damage and clouding of the eyes.

Vitamin K is needed for clotting. Excessive administration of synthetic vitamin K can produce liver damage.

The B complex vitamins usually exhibit their deficiency as a group and produce fatigue, irritability, skin changes, anaemia, burning feet, fissures at the angles of the mouth and a smooth red tongue. Excess vitamins are usually harmlessly excreted in the urine. Pregnant women may be given high doses of vitamin B6 (pyridoxine) to prevent vomiting. They can give birth to children with B6 dependency, and convulsions.

More than 65 mg a day of iron should not be taken. Excess iron gets deposited in organs like the liver, heart and thyroid, seriously damaging them.

More than 60 mg a day of zinc may be harmful. It can cause vomiting, diarrhoea, anaemia and nerve damage.

Amino acids are the basic building blocks of all protein. Protein deficiency owing to illness or malnutrition manifests itself with generalised swelling of the body and changes in the hair and nails. A few milligrams of amino acid in expensive capsules or a tonic will not help. A high protein diet needs to be eaten instead.

Iodine is provided in the “iodised salt” used for cooking. Supplements and tonics are sometimes fortified with additional iodine. This inadvertent intake can cause signs and symptoms of thyroid disease.

Pregnant women require folic acid supplements. Some expensive “women’s supplements” are marketed with additional vitamins, herbs and amino acids. This is not needed and may actually be dangerous.

Some special rejuvenating preparations for men contain sub optimal doses of herbs or precursors of androgenic steroids. The benefit is questionable.

Aware of this dangerous trend, government legislation has fixed the content of vitamin and mineral formulations. This has forced manufacturers to repackage vitamins as “dietary supplements” which are not under “price control” by adding trace elements, amino acids and minerals to the original formulation. The price is higher, but the proportions of the constituents are not scientific, nor are the advantages of the additives proved.

A sensible low fat diet supplemented with fresh fruits and vegetables (despite pollution and the use of fertilisers) supplies all the nutrients, vitamins and minerals needed. Supplements are required if the diet becomes inadequate as a result of premature birth, ageing, pregnancy, disease or food faddism.

Sources: The Telegraph (Kolkata, India)

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SAMe (S-Adenosyl methionine )

Other Names: SAM-e, S-adenosylmethionine

Definition:-
S-Adenosyl methionine (SAM) is a coenzyme involved in methyl group transfers. SAM was first discovered in Italy by G. L. Cantoni in 1952. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase EC 2.5.1.6. Transmethylation, transsulfuration, and aminopropylation are the metabolic pathways that use SAM. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver.

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The methyl group (CH3) attached to the methionine sulfur atom in SAM is chemically reactive. This allows donation of this group to an acceptor substrate in transmethylation reactions. More than 40 metabolic reactions involve the transfer of a methyl group from SAM to various substrates such as nucleic acids, proteins, and lipids.

In bacteria, SAM is bound by the SAM riboswitch, which regulates genes involved in methionine or cysteine biosynthesis.

The supplement SAMe is a synthetic form of a compound formed naturally in the body from the essential amino acid methionine and adenosine triphosphate (ATP), the energy-producing compound found in all cells in the body. It was first discovered in 1953.

SAMe is believed to work by being a methyl group donor in many reactions in the body. After donating the methyl group, it is converted to a compound called S-adenosyl-homocysteine.

Properties:-
Molecular formula: C15H23N6O5S+
Molar mass: 399.447

Biochemistry of S-adenosyl methionine:-

SAM cycle
The reactions that produce, consume, and regenerate SAM are called the SAM cycle. In the first step of this cycle, the SAM-dependent methylases (EC 2.1.1) that use SAM as a substrate produce S-adenosyl homocysteine as a product. This is hydrolysed to homocysteine and adenosine by S-adenosylhomocysteine hydrolase EC 3.3.1.1 and the homocysteine recycled back to methionine through transfer of a methyl group from 5-methyltetrahydrofolate, by one of the two classes of methionine synthases EC 2.1.1.13 or EC 2.1.1.14. This methionine can then be converted back to SAM, completing the cycle.

Polyamine biosynthesis
Another major role of SAM is in polyamine biosynthesis. Here, SAM is decarboxylated by Adenosylmethionine decarboxylase EC 4.1.1.50 to form S-adenosyl-5′-3-methylpropylamine. This compound then donates its n-propylamine group in the biosynthesis of polyamines such as spermidine and spermine from putrescine.

SAM is required for cellular growth and repair. It is also involved in the biosynthesis of several hormones and neurotransmitters that affect mood, such as dopamine and serotonin. Methyltransferases are also responsible for the addition of methyl groups to the 2′ hydroxyls of the first and second nucleotides next to the 5′ cap in messenger RNA.

Therapeutic uses
In the United States, SAM is sold as a nutritional supplement under the marketing name SAM-e (also spelled SAME or SAMe; pronounced “sam ee”). SAM is also marketed under the Gumbaral, Samyr, Adomet and Admethionine brand names. Some research has indicated that taking SAM on a regular basis may help fight depression, liver disease, and the pain of osteoarthritis. An authoritative report on SAMe is from the Agency for Healthcare Research and Quality (Dept Health and Human Services) at: http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=hstat1a.chapter.2159. Multiple clinical trials indicate benefits for depression, some liver conditions and osteoarthritis. All other indications are not yet proven.

Therapeutic use of SAM has increased as dietary supplements have gained in popularity, especially after the Dietary Supplement Health and Education Act was passed in 1994. This law allowed the distribution of SAM as dietary supplement, and therefore allowed it to bypass the regulatory requirements for drugs of the Food and Drug Administration (FDA).

At first, a line of evidence suggested that abnormally low levels of endogenous SAM may play an important role in the development of Alzheimer’s disease (AD) and that SAM may therefore have therapeutic potential in the treatment of AD (further research indicates this effect is likely due to Vitamin B12 deficiencies, which cause neurologic defects through one carbon transfers with folate). Severely low levels of SAM have been found in the cerebrospinal fluid and in all brain regions of AD patients examined. Preliminary research suggests SAM may have therapeutic potential in treating AD patients and a recent study using a mouse model of AD found that supplementary SAM prevented oxidative damage and cognitive impairment. In that study (available online), Tchantchou et al also explain the biomechanics that in addition to the above findings make low SAM a likely causal component of AD pathology.

Oral forms:
Oral SAMe achieves peak plasma concentrations 3 to 5 hours after ingestion of an enteric-coated tablet (400 – 1000 mg). The half-life is about 100 minutes. It may require up to one month for it to reach full effectiveness in treating osteoarthritis. Because of structural instability, stable salt forms of SAM are required for its use as an oral drug. The University of Maryland lists the commonly used salts: tosylate, butanedisulfonate, disulfate tosylate, disulfate ditosylate, and disulfate monotosylate.

With the advent of FDA-mandated Good Manufacturing Practices (GMPs) in 2008, manufacturers are required to confirm that their products contain what is listed on the label through the end of shelf life. Whether they achieve this goal or not has been questioned. Subscribers to Consumer Labs have access to a comparative report on SAMe content of various supplements.

Claims that the SAMe butanedisulfonate salt is more stable or better absorbed are not supported by the references that are usually cited as evidence. Different salts have successfully been used in clinical trials, but there is no published head-to-head comparison

Usage
SAMe is best absorbed on an empty stomach. Enteric-coated tablets packaged in foil or foil blister packs increase stability and improve absorption. SAMe should be stored in a cool, dry place to prevent deterioration.
People Use SAMe In:-
Osteoarthritis
There have been a number of studies on the effectiveness of SAMe in the treatment of osteoarthritis. SAMe appears to diminish osteoarthritis pain as effectively as non-steroidal anti-inflammatory medication. It appears to be well-tolerated.

Depression
There have been a number of studies on the use of SAMe for depression. It has been hypothesized that SAMe increases the availaibility of neurotransmitter serotonin and dopamine.

Liver disease
Some evidence suggests that SAMe may help people with liver disease. Preliminary research suggests it may help to normalize liver enzyme levels and help with cholestasis.

Possible side effects:-
SAM-e & Homocysteine: Once SAM-e donates its methyl group to choline, creatine, carnitine, DNA, tRNA, norepinephrine, and other compounds, it is transformed into S-adenosyl-homocysteine, (SAH). Under normal circumstances, homocysteine, in the presence of Vitamin B6, B12, and folic acid (SAM-e’s main co-factors), will eventually be converted back into methionine, SAM-e, or cysteine, glutathione, and other useful substances. However, if adequate amounts of these vitamins are not present, SAM-e will not break down properly. As a consequence, the full benefits of SAM-e will not be obtained, and homocysteine may increase to unsafe levels.

High levels of homocysteine have been associated with atherosclerosis (hardening and narrowing of the arteries), as well as an increased risk of heart attacks, strokes, liver damage, and possibly Alzheimer’s disease. Therefore, Vitamin B supplements are often taken along with SAM-e. These vitamins help metabolize the homocysteine into other useful compounds.

Another reported side effect of SAMe is insomnia, therefore the supplement is often taken in the morning. Other reports of mild side effects include lack of appetite, constipation, nausea, dry mouth, sweating, and anxiety/nervousness, but in placebo-controlled studies these side effects occur at about the same incidence in the placebo groups.

Therapeutic doses range from 400 mg/day to 1600 mg/day, although higher doses are used in some cases. Consult with your physician before and during use.

Adverse effects:-
Gastrointestinal disorder, diarrhea, dyspepsia, anxiety, headache, psychiatric, insomnia, allergy, and rashes. Long-term effects are unknown.

Serotonin syndrome:
There is concern and one report of the potentially fatal serotonin syndrome in association of SAMe with other medications.

Induction of mania:
In an extensive MEDLINE search on SAMe, Kagan found induction of mania in one patient out of fifteen treated with parenteral SAMe. In the same review, Lipinski found the apparent induction of mania in two patients with bipolar disorder (total of nine depressed patients studied).Both depression and mania can be life-threatening conditions that may cause cognitive dysfunction even after remission. There is concern that antidepressants in general can induce hypomania, mania, or both.

The safety of SAMe during pregnancy and during breastfeeding is unknown.

People with bipolar disorder, anxiety disorders and other psychiatric conditions should only use SAMe under the supervision of their healthcare provider. SAMe has been associated with hypomania and mania.

The most common side effects are digestive complaints, particularly nausea. Other side effects include skin rash, lowered blood sugar, dry mouth, blood in the stool, thirst, increased urination, headache, hyperactivity, anxiety and insomnia.

People with Parkinson’s disease should avoid SAM-e.

For more knowledge you may click to see
:->

S-Adenosyl-L-Methionine for Treatment of Depression, Osteoarthritis, and Liver Disease (Evidence Report/Technology Assessment:)

What Is SAMe

Disclaimer:The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

Resources:
http://en.wikipedia.org/wiki/S-Adenosyl_methionine
http://altmedicine.about.com/od/treatmentsfromatod/a/SAMe.htm

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Indian Dill (Anethum sowa)/Anethum graveolens

Botanical Name:Anethum sowa
Family: Apiaceae (ay-pee-AY-see-ee) (Info)
Genus: Anethum (uh-NAY-thum) (Info)
Species: sowa
Synonyms: Peucedanum graveolens ((L.)C.B.Clarke.), Anethum sowa (Roxb. ex Fleming.) A. graveloens[E] Lomatium graveolens var. graveolens[B,P] Lomatium kingii[B,P] Peucedanum kingii[B,P]

Sanskrit Name :Satahva

Other Common Names: From various places around the Web, may not be correct. See below.
Baston Do Diale [E], Catahva [E], Datli Boyana [E], Dereotu [E], Dill [L,B,H,S,P], Dille [D], East Indian Dill [E], Eneldo [E], Habbat Helwah [E], Hinojo [E], Indian Dill [H,E], Inojo [E], Inondo [E], King Desertparsley [P], Sadhab Al Barr [E], Surva [H],

Habitat :India, Pakisthan, Burma, Bangladesh and some other Asian Countries.(Surva) Pungent, somewhat more bitter variety extensively grown in India and Japan.Range: W. Asia. Naturalized in Europe in the Mediterranean.

Description:Annual growing to 0.75m by 0.15m . It is in leaf from May to November, in flower from April to July, and the seeds ripen from July to August. The scented flowers are hermaphrodite (have both male and female organs) and are pollinated by Bees. The plant is self-fertile. It is noted for attracting wildlife.

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Cultivation details:
An easily grown plant, it prefers a moderately rich loose soil and full sun. Requires a well-drained soil and shelter from the wind. Tolerates a pH in the range 5.3 to 7.8.

Dill is a commonly cultivated herb, especially in warm temperate and tropical zones. It is grown mainly for its edible leaves and seeds, though it is also used medicinally. There are many named varieties. ‘Bouquet’ is an American cultivar that has a prolific production of seeds. The sub-species A. graveolens sowa from India has a slightly different flavour to the type species. The plant quickly runs to seed in dry weather. It often self-sows when growing in a suitable position.

A good companion for corn and cabbages, also in moderation for cucumbers, lettuce and onions, but it inhibits the growth of carrots. Dill reduces a carrot crop if it is grown to maturity near them. However, the young plant will help to deter carrot root fly.

The plant prefers light (sandy) and medium (loamy) soils and requires well-drained soil. The plant prefers acid, neutral and basic (alkaline) soils. It cannot grow in the shade. It requires moist soil.

Propagation
Seed – sow April to early summer in situ and only just cover. The seed germinates in 2 weeks if the soil is warm. A regular supply of leaves can be obtained if successional sowings are made from May to the end of June. Autumn sowings can succeed if the winters are mild. Dill is very intolerant of root disturbance and should not be transplanted because it will then quickly run to seed.

Other details:This plant is attractive to bees, butterflies and/or birds
Average Water Needs; Water regularly; do not overwater
Flowers are good for cutting.

Edible Uses
Condiment; Leaves; Seed; Tea.
Leaves – raw or cooked. Used as a flavouring in salads etc. The leaves lose their flavour if the are cooked for any length of time and so are best used raw or added to cooked dishes only a few minutes before the cooking is complete. The leaves can be harvested at any time the plant is growing, but are best just before the plant flowers. Per 100g, the plant contains 253 calories, 7.2g water, 20g protein, 4.4g fat, 55.8g carbohydrate, 11.9g fibre, 12.6g ash, 1784mg calcium, 543mg phosphorus, 48.8mg iron, 451mg magnesium, 208mg sodium, 3,308mg potassium, 3.3mg zinc, 0.42mg thiamine, 0.28mg riboflavin, 2.8mg niacin and 1.5mg vitamin B6.

Seed – raw or cooked. Very pungent and bitter in taste. It is used as a flavouring in salads, preserves etc, its chief uses being perhaps in making dill vinegar and as a flavouring in pickled gherkins. It can also be sprouted and used in breads, soups and salad dressings. Per 100g, the seed contains 305 calories, 7.7g water, 14.5g fat (0.73g saturated, 124mg phytosterol and no cholesterol), 55.2g carbohydrate, 21g fibre, 6.7g ash, 1,516mg calcium, 277mg phosphorus, 16.3mg iron, 256mg magnesium, 20mg sodium, 1,186mg potassium, 5.2mg zinc, 53IU vitamin A, 0.42mg thiamine and 0.28mg riboflavin.

An essential oil from the seed is used as a flavouring in the food industry.

A tea is made from the leaves and/or the seeds.

Composition
Seed (Fresh weight)
In grammes per 100g weight of food:
Water: 7.7 Calories: 305 Fat: 14.5 Carbohydrate: 55.2 Fibre: 21.1 Ash: 6.7
In milligrammes per 100g weight of food:
Calcium: 1516 Phosphorus: 277 Iron: 16.3 Magnesium: 256 Sodium: 20 Potassium: 1186 Zinc: 5.2 VitaminA: 53 Thiamine: 0.42 Riboflavin: 0.28

Leaves (Fresh weight)
In grammes per 100g weight of food:
Water: 7.2 Calories: 253 Protein: 20 Fat: 4.4 Carbohydrate: 55.8 Fibre: 11.9 Ash: 12.6
In milligrammes per 100g weight of food:
Calcium: 1784 Phosphorus: 543 Iron: 48.8 Magnesium: 451 Sodium: 208 Potassium: 3308 Zinc: 3.3 Thiamine: 0.42 Riboflavin: 0.28 Niacin: 2.8 VitaminB6: 1.5

Medicinal Uses:
Antihalitosis; Aromatic; Carminative; Diuretic; Galactogogue; Stimulant; Stomachic.

Dill has a very long history of herbal use going back more than 2,000 years. The seeds are a common and very effective household remedy for a wide range of digestive problems. An infusion is especially efficacious in treating gripe in babies and flatulence in young children.

The seed is aromatic, carminative, mildly diuretic, galactogogue, stimulant and stomachic. It is also used in the form of an extracted essential oil. Used either in an infusion, or by eating the seed whole, the essential oil in the seed relieves intestinal spasms and griping, helping to settle colic. Chewing the seed improves bad breath. Dill is also a useful addition to cough, cold and flu remedies, it can be used with antispasmodics such as Viburnum opulus to relieve period pains. Dill will also help to increase the flow of milk in nursing mothers and will then be taken by the baby in the milk to help prevent colic.

Claimed Therapeutic Use
(According to Ayurveda): For improving hunger, appetiser, anti-febric, vermifugal, digestive, abdominal colic, intestinal colic, ophthalmic disorders, pelvic inflammatory disease conditions, analgesic, body pain .

Other Uses
Essential; Insecticide.
The seed contains up to 4% essential oils. It is used in perfuming soaps, medicines and as a food flavouring.
Some compounds of dill (d-carvone is mentioned as one of them), when added to insecticides, have greatly increased the effectiveness of the insecticides.

Fresh foliage is eaten with steamed rice and used to flavour soup. Essential ingredient in curry powders. Fruits are carminative, stomachic and stimulant; and so are used chiefly for flatulence. Oil is used in the pharmaceutical and perfumery industries.

Disclaimer:The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider

Resources:
http://davesgarden.com/guides/pf/go/62272/index.html
http://en.wikipedia.org/wiki/List_of_herbs_and_minerals_in_Ayurveda
http://www.sacredseed.com/ricanes.htm
http://www.ibiblio.org/pfaf/cgi-bin/arr_html?Anethum+graveolens

Seborrhea Dermatitis


An infant with Cradle CapImage via Wikipedia

Definition: Seborrhea (say: seb-uh-ree-uh) is a common skin problem. It causes a red, itchy rash and white scales. When it affects the scalp, it is called “dandruff.” It can be on parts of the face as well, including the folds around the nose and behind the ears, the forehead, and the eyebrows and eyelids. On the body, seborrhea often occurs in the middle part of the chest, around the navel and in the skin folds under the arm, below the breasts and in the groin and buttocks area.

Seborrhoeic eczema (also Seborrheic dermatitis AmE, seborrhea) is a skin disorder affecting the scalp, face, and trunk causing scaly, flaky, itchy, red skin. It particularly affects the sebum-gland rich areas of skin.

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Who gets seborrhea?
Infants may get seborrhea. It’s known as “cradle cap.” Cradle cap goes away after about 6 months. It may also affect the diaper area and look like a diaper rash.

Seborrhea also affects adults and elderly persons, and is more common in men than in women. Seborrhea occurs more frequently in persons with oily skin.

It affects 3 percent of the general population. It occurs more commonly in older people who are bedridden or have neurologic conditions such as Parkinson’s disease. Seborrhea also affects almost 85 percent of people with AIDS.

Causes:The cause of seborrheic dermatitis is not fully understood, although many factors have been implicated.. It is likely that a number of factors, such as hormones and stress, can cause it.
The widely present yeast, Malassezia furfur (formerly known as Pityrosporum ovale), is involved, as well as genetic, environmental, hormonal, and immune-system factors. A theory that seborrhoeic dermatitis is an inflammatory response to the yeast has not been proven. Those afflicted with seborrhoeic dermatitis have an unfavourable epidermic response to the infection, with the skin becoming inflamed and flaking.

Acute form of seborrhoeic dermatitis on scalpIn children, excessive vitamin A intake can cause seborrhoeic dermatitis. Lack of biotin, pyridoxine (vitamin B6) and riboflavin (vitamin B2) may also be a cause.

It is a chronic inflammatory skin disorder that affects the areas of the head and trunk that have sebaceous glands. A type of yeast that has an affinity for these glands called Pityrosporum ovale may be the cause, but this has not been proven yet. It is believed that the build-up of yeast in these glands irritates the skin causing redness and flaking.

Seborrhea is more common in men than women and affects 3 percent of the general population. It occurs more commonly in older people who are bedridden or have neurologic conditions such as Parkinson’s disease. Seborrhea also affects almost 85 percent of people with AIDS.

Diagnosis:

Clinical Manifestations
Seborrheic dermatitis typically affects areas of the skin where sebaceous glands appear in high frequency and are most active. The distribution is classically symmetric, and common sites of involvement are the hairy areas of the head, including the scalp , the scalp margin , eyebrows, eyelashes, mustache and beard. Other common sites are the forehead , the nasolabial folds , the external ear canals and the postauricular creases. Seborrhea of the trunk may appear in the presternal area and in the body folds, including the axillae, navel, groin, and in the inframammary and anogenital areas. Figure 7 illustrates the typically symmetric distribution of seborrheic dermatitis.

More severe seborrheic dermatitis is characterized by erythematous plaques frequently associated with powdery or greasy scale in the scalp (Figure 8), behind the ears (Figure 9) and elsewhere in the distribution described above. Besides an itchy scalp, patients may complain of a burning sensation in facial areas affected by seborrhea. Seborrhea frequently becomes apparent when men grow mustaches or beards and disappears when the facial hair is removed. If left untreated, the scale may become thick, yellow and greasy and, occasionally, secondary bacterial infection may occur.

Seborrheic dermatitis is more common in men than in women, probably because sebaceous gland activity is under androgen control. Seborrhea usually first appears in persons in their teens and twenties and generally follows a waxing/waning course throughout adulthood.

UV-A and UV-B light inhibit the growth of P. ovale,9 and many patients report improvement in seborrhea during summer.

Treatment:
Soaps and detergents such as sodium laureth sulfate may precipitate a flare-up, as they strip moisture from the top layers of the skin, and the drying property of these can cause flare-ups and may worsen the condition. Accordingly a suitable alternative should be used instead.

Among dermatologist recommended treatments are shampoos containing coal tar, ciclopiroxolamine, ketoconazole, selenium sulfide, or zinc pyrithione. For severe disease, keratolytics such as salicylic acid or coal tar preparations may be used to remove dense scale. Topical terbinafine solution (1%) has also been shown to be effective in the treatment of scalp seborrhoea, as may lotions containing alpha hydroxy acids or corticosteroids (such as fluocinolone acetonide). Pimecrolimus topical lotion is also sometimes prescribed.

Chronic treatment with topical corticosteroids may lead to permanent skin changes, such as atrophy and telangiectasia.

UV-A and UV-B light inhibit the growth of M. furfur, although caution should be taken to avoid sun damage.

According to the American Academy of Family Physicians(AAFP), one treatment that has proven successful, especially when steroid topicals and shampoos aren’t working, and the patient continues to suffer from rapid hair loss and rashes, has been low doses(10mg-30mg daily) of the perscription drug Accutane,(Isotretinoin). The exact mechanism isn’t known, but it is thought to work by reducing sebum, which plays an important role in seborrhoeic dermatitis. Patients should be evaluated monthly, while examing the proper liver functions when putting a patient on accutane therapy. Special screening should be in place for women patients, because of the risk of birth defects. This therapy can last, when the condition is chronic and the isotretinoin does is low, for years. But, patients should be given a one to two month break off this particular therapy every 6 months to see if the condition still is affecting the patient

Adults who have seborrhea usually experience a waxing and waning course. In other words it can’t be “cured”. The good news is with proper maintenance, seborrhea can be controlled. Furthermore, most of the treatments can be found over-the-counter.

Treatment will help keep seborrhea under control. It’s important to keep your body clean.

Dandruff Shampoo
If you have dandruff, use medicated shampoos.

When using dandruff shampoo, first wet your hair. Rub some shampoo into your scalp and hair. Leave the shampoo on your scalp and hair for at least 5 minutes. Then rinse it out. Use the dandruff shampoo every day until your dandruff goes away. Then use the medicated shampoo 2 or 3 times a week to keep dandruff away. Having dandruff does not mean that your scalp is too dry! Dandruff comes because you need to wash your hair more often.

Medicated Shampoos should always be used.For black persons, daily shampooing may not be needed. Ask your doctor about a special steroid preparation in oil that can be used on the scalp like a pomade. Or you can use a steroid-containing shampoo.

Adults who have seborrhea usually experience a waxing and waning course. In other words it can’t be “cured”. The good news is with proper maintenance, seborrhea can be controlled. Furthermore, most of the treatments can be found over-the-counter.

Proper hygiene plays an important role in treatment. Frequent washing with soap gets rid of the oils in the affected areas and improves symptoms. Sunlight inhibits the growth of the yeast; therefore exposure of affected areas to sun is helpful, although caution should be exercised to avoid sun damage. The main medical treatments are antifungal shampoos and topical.

Cradle Cap:
Cradle cap in infants also gets better with daily shampooing. First try a mild, nonmedicated baby shampoo. If that doesn’t work, try an a dandruff shampoo. If the patch of cradle cap is large and thick, first try softening it by rubbing on warm mineral oil. Next, gently brush with a baby hairbrush. Then use shampoo.

Seborrhea Shampoos
There are several good antifungal shampoos on the market that can be purchased without a prescription. The main shampoos are selenium sulfide found in Selsun, pyrithione zinc found inHead & Shouldersulders and Sebulon, coal tar found in Sebutone and Tegrin, and finally ketoconazole found in Nizoral.

All of these shampoos have a medicated smell. The way to use them is to shampoo and leave on for at least 10 minutes then rinse off. The shampoos can be used on the face and other parts of the body as a lotion with the same instructions as long as precaution is used around the eyes. Do this daily until the redness and flaking is controlled then use 2-3 times a week as needed to keep symptoms from returning.

Topical Steroids For Seborrhea
Topical steroids reduce the inflammatory response and help control itching. You can buy hydrocortisone cream 1% over-the-counter, and it’s safe to use on the face. Apply twice a day to the affected area until the redness resolves. Save the hydrocortisone for flare-ups and use the antifungal shampoo for maintenance because long-term steroid use can cause side effects like acne and thinning of the skin.

Herbal Treatment:The World Health Organization mentions Aloe vera gel as a yet to be scientifically proven traditional medicine treatment for Seborrhoeic dermatitis.

*Arctium lappa (Burdock) oil
*Chelidonium majus (Celandine)
*Glycyrrhiza glabra (Licorice)
*Melaleuca (Tea tree) species
*Plantago (Plantain) species
*Symphytum officinale (Comfrey)
*Zingiber officinale (Ginger) root juice
*Ledebouriella Seseloides (Fang Feng)
*Smilax China (Smilax china)
*Trichosanthes Kirilowii (Snakegourd)
*Glycyrrhiza Uralensis
*Coptis Chinensis (Chinese goldthread)
*Phellodendron Amurense (Huang Bai)
*Sophora Flavescens
*Centella Asiatica (Gotu Kola)
*Evening primrose,
*dandelion root
*red clover Norwegian kelp
* berberine (from barberry, Oregon grape root or goldenseal).

Quik Tip: Evening primrose – anti-inflammatory herb of the first magnitude; it helps your

body balance itself hormonally, too.

Click to learn more about Seborrheic Dermatitis


Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Resources:
http://en.wikipedia.org/wiki/Seborrheic_dermatitis
http://www.herbnews.org/seborrheadone.htm
http://dermatology.about.com/cs/seborrhea/a/sebderm.htm
http://www.aafp.org/afp/20000501/2703.html

http://en.wikipedia.org/wiki/Taraxacum

 

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Amazing Effects of Bananas

Click & See the pictures

“NEVER PUT BANANA IN THE REFRIGERATOR

Bananas contain three natural sugars – sucrose,fructose and glucose
combined with fiber. A banana gives an instant,
sustained and substantial boost of energy.

Research has proven that just two bananas
provide enough energy for a strenuous 90-minute workout.
No wonder banana is the number one fruit with the world’s leading athletes.

But energy isn’t the only way a banana can
help us keep fit.
It can also help overcome or prevent a substantial
number of illnesses and conditions, making it a must to add to our daily diet..

Depression: According to a recent survey
undertaken by MIND amongst people suffering from depression, many felt much better after eating a banana. This is because bananas contain
tryptophan, a type of protein that the body converts into serotonin,known to make you relax, improve your mood and generally make you
feel happier.

PMS: Forget the pills – eat a banana… The
vitamin B6 it contains regulates blood glucose levels, which can affect your mood.

Anemia: High in iron, bananas can stimulate
the production of hemoglobin in the blood and so helps in cases of anemia.

Blood Pressure: This unique tropical fruit is
extremely high in potassium yet low in salt, making it perfect to beat blood pressure.
So much so, the US Food and Drug Administration
has just allowed the banana industry to make official claims for the fruit’s ability to reduce the risk of blood pressure and stroke.

Brain Power: 200 students at a Twickenham
(Middlesex) school were
helped through their exams this year by eating bananas at breakfast,break, and lunch in a bid to boost their brain power. Research has
shown that the potassium-packed fruit can assist
learning by making pupils more alert.

Constipation: High in fiber, including bananas
in the diet can help restore normal bowel action, helping to overcome the problem without resorting to laxatives.

Hangovers: One of the quickest ways of curing
a hangover is to make a banana milkshake,sweetened with honey.The banana calms the stomach and, with the help of the honey, builds up depleted blood sugar levels, while the milk soothes and re-hydrates your system.

Heartburn: Bananas have a natural antacid effect
in the body, so if you suffer from heartburn, try eating a banana for soothing relief.

Morning Sickness: Snacking on bananas between
meals helps to keep blood sugar levels up and avoid morning sickness.

Mosquito bites: Before reaching for the insect
bite cream, try rubbing the affected area with the inside of a banana skin. Many people find it amazingly successful at reducing swellingand irritation.

Nerves: Bananas are high in B vitamins that
help calm the nervous system.
Overweight and at work? Studies at the Institute
of Psychology in Austria found pressure at wor k leads to gorging on comfort food like chocolate and chips. Looking at 5,000 hospital patients,
researchers found the most obese were more
likely to be in high-pressure jobs. The report concluded that,to avoid panic-induced food cravings, we need to control our blood sugar
levels by snacking on high carbohydrate foods
every two hours to keep levels steady.

Ulcers: The banana is used as the dietary food
against intestinal disorders because of its soft texture and smoothness. It is the only raw fruit that can be eaten without distress in over-chronicler cases. It also neutralizes over-acidity and reduces irritation by coating the lining of the stomach.

Temperature control: Many other cultures see
bananas as a’cooling’ fruit that can lower both the physical and emotional temperature of expectant mothers. In Thailand ,for example,
pregnant women eat bananas to ensure their baby
is born with a cool temperature.

Seasonal Affective Disorder (SAD): Bananas can
help SAD sufferers because they contain the natural mood enhancer tryptophan.

Smoking &Tobacco Use: Bananas can also
help people trying to give up smoking. The B6, B12 they contain, as well as
the potassium and magnesium found in them, help the body recover from the effects of nicotine withdrawal.

Stress: Potassium is a vital mineral, which
helps normalize the heartbeat, sends oxygen to the brain and regulates your body’s water
balance. When we are stressed, our metabolic
rate rises, thereby reducing our potassium levels. These can be rebalanced with the help
of a high-potassium banana snack.

Strokes: According to research in The New
England Journal of Medicine, eating bananas as part of a regular diet can cut the risk
of death by strokes by as much as 40%!

Warts:
Those keen on natural alternatives swear
that if you want to kill off a wart, take a piece of banana skin and place it on the wart, with the yellow side out. Carefully hold the skin in place
with a plaster or surgical tape!

So, a banana really is a natural remedy for many ills. When you compare it to an apple, it has four times the protein, twice the
carbohydrate, three times the phosphorus, five
times the vitamin A and iron, and twice the other vitamins and minerals. It is also rich in potassium and is one of the best value foods around So maybe its time to change that well-known phrase so that we say,
‘A banana a day keeps the doctor away!’

May I add one here; want a quick shine on our
shoes??
Take the INSIDE
of the banana skin, and rub directly on the
shoe…polish with dry cloth.
An Amazing fruit ! Is’nt it?

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