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News on Health & Science

Algae May Harbour SARS Cure

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A protein from algae might help in treating Severe Acute Respiratory Syndrome (SARS) infections, suggests a new study.

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Researchers from University of Iowa have found that mice treated with the protein, Griffithsin (GRFT), had a 100 percent survival rate after exposure to the SARS coronavirus (SARS-CoV), as compared to a 30 percent survival for untreated mice.

GRFT is believed to exert its anti-viral effects by altering the shape of the sugar molecules that line the virus‘ envelope, allowing it to attach to and invade human cells, where it takes over the cells’ reproductive machinery to replicate itself.

Without that crucial ability, the virus is unable to cause disease.

“While preliminary, these results are very exciting and indicate a possible therapeutic approach to future SARS or other coronaviral outbreaks,” said Christine Wohlford-Lenane, senior research assistant at the department of pediatrics University of Iowa and the lead author of the study.

GRFT not only stop the virus from replicating, but also prevented secondary outcomes, such as weight loss, that are associated with infection.

“We are planning future studies to investigate prophylaxis, versus treatment interventions with GRFT, in the SARS mouse model in collaboration with Barry O’Keefe at the National Cancer Institute,” she said.

“In addition, we want to learn whether mice protected from SARS by GRFT develop protective immunity against future infection,” she added.

The research was presented at the American Thoracic Society‘s 105th International Conference in San Diego.

Source: The Times Of India

 
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Ailmemts & Remedies

Amebic Liver Abscess

Alternative Names:Hepatic amebiasis; Extraintestinal amebiasis; Abscess – amebic liver
Definition :
Amebic liver abscess is a collection of pus in the liver caused by an intestinal parasite.Organisms that carry disease can travel through the blood stream into the liver and form an abscess, a collection of infected tissue and pus.

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Amebic liver abscess is an extraintestinal manifestation caused by a protozoa Entamoeba histolytica. The disease spreads through the ingestion of cysts in fecally-contaminated food or water. The infection is worldwide, most common in tropical areas usually in developing countries where poor sanitation exist.

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This is an Abscess (walled area of infection/pus) in the liver that is caused by the organism Entamoeba histolytica.  It is common in tropical and subtropical areas (southeast Asia, Africa, India, Latin America).  In the U.S., it is most common in young Hispanic adults.  It is also seen in those with recent travels to tropical areas, homosexuals, and among the inhabitants of institutions for the mentally ill.

Causes :-
Travel to endemic areas (as above), where the cysts of the parasite may be ingested by consuming water or food contaminated by fecal matter.
Amebic liver abscess is caused by Entamoeba histolytica, the same organism that causes amebiasis, an intestinal infection. The organism is carried by the blood from the intestines to the liver.

The disease spreads through ingestion of cysts in fecally-contaminated food or water, use of human waste as fertilizer, and person-to-person contact.

The infection occurs worldwide, but is most common in tropical areas where crowded living conditions and poor sanitation exist. Africa, Latin America, Southeast Asia, and India have significant health problems associated with this disease.

Risk Factors :-
*Malnutrition
*Old age
*Pregnancy
*Steroid use
*Cancer
*Immunosuppression
*Alcoholism
*Recent travel to a tropical region
*Homosexuality, particularly in males

Symptoms :-
There may or may not be symptoms of intestinal infection. Symptoms may include:
*Right upper abdominal pain
*Right sided chest pain worse on a deep breath
*Intense, continuous, or stabbing pain
*Chills
*Diarrhea precedes infection in 20% of patients
*Fever
*General discomfort, uneasiness, or ill feeling (malaise)
*Jaundice
*Joint pain
*Loss of appetite
*Sweating
*Weight loss
*malaise

Nature of the disease:-
Most infected people, perhaps 90%, are asymptomatic, but this disease has the potential to make the sufferer dangerously ill. It is estimated by the World Health Organization that about 70,000 people die annually worldwide.

Infections can sometimes last for years. Symptoms take from a few days to a few weeks to develop and manifest themselves, but usually it is about two to four weeks. Symptoms can range from mild diarrhoea to dysentery with blood and mucus. The blood comes from amoebae invading the lining of the intestine. In about 10% of invasive cases the amoebae enter the bloodstream and may travel to other organs in the body. Most commonly this means the liver, as this is where blood from the intestine reaches first, but they can end up almost anywhere.

Onset time is highly variable and the average asymptomatic infection persists for over a year. It is theorised that the absence of symptoms or their intensity may vary with such factors as strain of amoeba, immune response of the host, and perhaps associated bacteria and viruses.

In asymptomatic infections the amoeba lives by eating and digesting bacteria and food particles in the gut, a part of the gastrointestinal tract. It does not usually come in contact with the intestine itself due to the protective layer of mucus that lines the gut. Disease occurs when amoeba comes in contact with the cells lining the intestine. It then secretes the same substances it uses to digest bacteria, which include enzymes that destroy cell membranes and proteins. This process can lead to penetration and digestion of human tissues, resulting first in flask-shaped ulcers in the intestine. Entamoeba histolytica ingests the destroyed cells by phagocytosis and is often seen with red blood cells inside when viewed in stool samples. Especially in Latin America,  a granulomatous mass (known as an amoeboma) may form in the wall of the ascending colon or rectum due to long-lasting immunological cellular response, and is sometimes confused with cancer.

Theoretically, the ingestion of one viable cyst can cause an infection.

Diagnosis:
Exams and Tests
Tests that may be done include:
*Abdominal ultrasound
*Abdominal CT scan or MRI
*Complete blood count
*Liver biopsy – rarely done due to high risk of complications
*Liver scan
*Liver function tests
*Serology for amebiasis

Treatment
A medicine called metronidazole (Flagyl) is the usual treatment for liver abscess. Medications such as paromomycin must also be taken to remove intestinal amebiasis to prevent recurrence of the disease.

In rare cases, the abscess may need to be drained to help relieve some of the abdominal pain.

Prognosis:
Without treatment, the abscess may rupture and spread into other organs, leading to death. Persons who receive treatment have a very high chance of a complete cure or having only minor complications.
Possible Complications :In the majority of cases, amoebas remain in the gastrointestinal tract of the hosts. Severe ulceration of the gastrointestinal mucosal surfaces occurs in less than 16% of cases. In fewer cases, the parasite invades the soft tissues, most commonly the liver. Only rarely are masses formed (amoebomas) that lead to intestinal obstruction.

The abscess may rupture into the abdominal cavity, the lining of the lungs, the lungs, or the sac around the heart. The infection can also spread to the brain.

When to Contact a Medical Professional
Call your health care provider if symptoms develop after travel to an area where the disease is known to occur.

Prevention:
To help prevent the spread of amoebiasis around the home :
*Wash hands thoroughly with soap and hot running water for at least 10 seconds after using the toilet or changing a baby’s diaper, and before handling food.
*Clean bathrooms and toilets often; pay particular attention to toilet seats and taps.
*Avoid sharing towels or face washers.

To help prevent infection:
*Avoid raw vegetables when in endemic areas, as they may have been fertilized using human feces.
*Boil water or treat with iodine tablets.
*When traveling in tropical countries where poor sanitation exists, drink purified water and do not eat uncooked vegetables or unpeeled fruit.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Resources:
http://www.nlm.nih.gov/medlineplus/ency/article/000211.htm
http://www.ecureme.com/emyhealth/data/Amebic_Liver_Abscess.asp
http://organizedwisdom.com/Amebic_Liver_Abscess
http://organizedwisdom.com/helpbar/index.html?return=http://organizedwisdom.com/Amebic_Liver_Abscess&url=en.wikipedia.org/wiki/Amoebiasis#Diagnosis_of_human_illness

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Suppliments our body needs

Why Sunlight is Your Best Source of Vitamin D

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In fact, vitamin D plays a pivotal role in the immune system. The explanation likely comes from the fact that vitamin D in cod liver oil does not exist in isolation — it comes with a high dose of vitamin A.

Vitamin A and vitamin D compete for each other’s function. For example, even the vitamin A in a single serving of liver can impair vitamin D’s rapid intestinal calcium response.

Unfortunately, Americans tend to consume multivitamins or cod liver oil that contain disproportionately small amounts of vitamin D, but detrimental quantities of vitamin A. One manufacturer sells cod liver oil containing only 3 to 60 IU of vitamin D, but between 3,000 and 6,000 IU of vitamin A.

A separate study by Daniel Hayes, Ph.D., of the New York City Department of Health and Mental Hygiene also suggests that a form of vitamin D could be one of your body’s main protections against damage from low levels of radiation. Hayes explains that calcitriol, the active form of vitamin D, may protect us from background radiation and could be used as a safe protective agent before or after a low-level nuclear incident.

He points out that calcitriol is involved in cell cycle regulation and control of proliferation, cellular differentiation and communication between cells, as well as programmed cell death (apoptosis and autophagy) and antiangiogenesis.

Calcitriol is the form of vitamin D that activates your body’s Vitamin D Receptor (VDR), which allows gene transcription to take place and the activation of the innate immune response.

It is possible that several of the transcriptions by the VDR will help transcribe proteins that protect the body against radiation.

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Categories
Featured News on Health & Science

Why Brain Surgeons Are Avoiding Cell Phones?

The use of a mobile phone is prohibited in some train company carriages

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Last week, three prominent neurosurgeons told CNN interviewer Larry King that they did not hold cell phones next to their ears. Dr. Keith Black, Dr. Vini Khurana, and CNN’s chief medical correspondent, Dr. Sanjay Gupta all maintained that the practice could be unsafe.

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Along with Senator Edward M. Kennedy’s recent diagnosis of a glioma, a type of tumor that critics have long associated with cell phone use, the doctors’ remarks have helped reignite the debate about cell phones and cancer.

According to the Food and Drug Administration, three large epidemiology studies since 2000 have shown no harmful effects. However, that the average period of phone use in those studies was about three years, which provides no information about the long-term exposures that could lead to cancer.

“What we’re seeing is suggestions in epidemiological studies that have looked at people using phones for 10 or more years,” says Louis Slesin, editor of Microwave News, an industry publication that tracks the research.
.
Sources:

* New York Times June 3, 2008

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News on Health & Science

Mystics and Medicine

Are we being hoodwinked by alternative medicine? ……Two leading scientists examine the evidence. The first of a two-part extract from Trick or Treatment: Alternative Medicine on Trial by Simon Singh and Edzard Ernst:
MIRACLE CURE? Alexander Technique,……… aromatherapy and magnet therapy


Which therapies work and which ones are useless? Which therapies are safe and which ones are dangerous? These are questions that doctors have asked themselves for millennia in relation to all forms of medicine.

And yet it is only comparatively recently that they have developed an approach that allows them to separate the effective from the ineffective, and the safe from the dangerous.

This approach, known as evidence-based medicine, has revolutionised medical practice, transforming it from an industry of charlatans and incompetents into a system of healthcare that can deliver such miracles as transplanting kidneys, removing cataracts, combating childhood diseases, eradicating smallpox and saving millions of lives each year.

Evidence-based medicine is about using the current best evidence — gathered through clinical trials and other scientific investigations — to make medical decisions. Alternative medicine claims to be able to treat the same illnesses and diseases that conventional medicine tries to tackle.

We set out to establish the truth of these claims by using the principles of evidence-based medicine.

Some people will be suspicious of this, perceiving evidence-based medicine as a strategy for allowing the medical establishment to defend its own members and treatment, while excluding outsiders who offer alternative treatments.

In fact, the opposite is often true — evidence-based medicine actually allows outsiders to be heard; it endorses any treatment that turns out to be effective, however strange it may seem.

In the 18th century, for instance, lemon juice as a treatment for scurvy was regarded as implausible but the establishment had to accept it because it was backed up by evidence from trials.

We had no axe to grind — indeed Professor Ernst even practised as a homeopath for many years (as well as receiving treatment as a patient) — and we came to our conclusions based on a fair, thorough and scientific assessment of the evidence.

So what did we find? While some therapies do provide some health benefits (e.g. osteopathy), most have nothing to offer.

Many popular therapies are “effective” only because they are good at eliciting a placebo response; making the patient feel better simply because they believe the treatment will help.

You might feel that as placebos help patients, this alone justifies the use of the therapy. But any treatment that relies on the placebo effect is essentially a bogus treatment. And it’s far from cheap.

If alternative practitioners are making unproven, disproven or vastly exaggerated claims, and if their treatments carry risks, then we are being swindled at the expense of our own good health.

Too many alternative therapists remain uninterested in determining the safety and efficacy of their interventions. These practitioners also fail to see the importance of rigorous clinical trials in establishing proper evidence for or against their treatments — where evidence already exists that treatments are ineffective or unsafe, alternative therapists carry on regardless.

Despite this disturbing situation, the market for alternative treatments is booming, and the public is being misled over and over again, often by misguided therapists; sometimes by exploitative charlatans.

It is time for the tricks to stop, and for the real treatments to take priority. The same scientific standards, evaluation and regulation should be applied to all types of medicine.

If this doesn’t happen, then homeopaths, acupuncturists, chiropractors, herbalists and many other alternative therapists will continue to prey on the most vulnerable — raiding their wallets, offering false hope and even endangering their health.

ALEXANDER TECHNIQUE:-

WHAT IS IT?….. A technique for relearning correct posture and body movements. Alexander teachers guide their clients through exercise sessions using a gentle, hands-on approach. As plenty of repetition is needed, 30 to 100 such sessions are usually required to master the technique, demanding a considerable level of commitment from the client, in terms of both time and money.

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DOES IT WORK? ……Very little research so far has been conducted on the technique. Some promising findings have emerged in terms of improvement of respiratory function, reduction of anxiety, reduction of disability in Parkinson’s disease and improvement of chronic back pain.

However, for none of these conditions is the evidence sufficient to claim that the Alexander technique is effective.

AROMATHERAPY:-

WHAT IS IT?
Plant essences (known as “essential oils”) are used to treat or prevent illnesses or enhance wellbeing. Most commonly, the diluted oil is applied to the skin via a gentle massage, but it can also be added to a bath or diffused in the air.

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Aromatherapists believe that different essential oils have different specific effects. Aromatherapy is advocated for chronic conditions such as anxiety, tension headache and musculoskeletal pain.

DOES IT WORK? Some clinical trials confirm the relaxing effects of aromatherapy massage. However, this is usually short-lived and therefore of debatable therapeutic value. Some essential oils do seem to have specific effects. For instance, tea tree has anti-microbial properties. However, these effects are far less reliable than those of conventional antibiotics. There is no evidence that aromatherapy can treat specific diseases.


CHIROPRACTIC THERAPY:-

WHAT IS IT? Chiropractors use spinal manipulation to realign the spine to restore mobility. Spinal manipulation can be a fairly aggressive technique, which pushes the spinal joint slightly beyond what it is ordinarily capable of achieving, using a technique called high-velocity, low-amplitude thrust — exerting a relatively strong force in order to move the joint at speed, but the extent of the motion needs to be limited to prevent damage to the joint and its surrounding structures.

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Some chiropractors claim to treat everything from digestive disorders to ear infections, others will treat only back problems.

DOES IT WORK?
There is no evidence to suggest that spinal manipulation is effective for anything but back pain and even then conventional approaches (such as regular exercise and ibuprofen) are just as likely to be effective and are cheaper. Neck manipulation has been linked to neurological complications such as strokes — in 1998, a 20-year-old Canadian woman died after neck manipulation caused a blood clot which led to stroke. We would strongly recommend physiotherapy exercises and osteopathy ahead of chiropractic therapy because they are at least effective and much safer. The dangers of chiropractic therapy to children are particularly worrying because a chiropractor would be manipulating an immature spine.


HYPNOTHERAPY:-

WHAT IS IT? The use of hypnosis, a trance-like state, for therapeutic purposes. Hypnotherapists treat a range of chronic conditions, including pain, anxiety, addictions and phobias.

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DOES IT WORK?
Dozens of clinical trials show that hypnotherapy is effective in reducing pain, anxiety and the symptoms of irritable bowel syndrome. However, the evidence is that it’s not effective to help you stop smoking, even though it is frequently promoted in this context.


MAGNET THERAPY:-

WHAT IS IT? The use of magnetic fields from static magnets, which are usually worn on the body, to treat various conditions, most frequently pain. These days rapidly fluctuating magnetic fields are used in conventional medicine in high-tech imaging machines (such as MRI scanners) and for promoting the healing of bone fractures. However, alternative medicine tends to use static magnets, which create a permanent magnetic field, to treat many conditions, mostly to alleviate chronic pain.

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DOES IT WORK? There is no evidence that static magnets offer any medical benefit for pain relief. As they are usually self-administered, there is a danger of missing serious diagnoses and losing valuable time for early treatment of serious diseases.

OSTEOPATHY:-

WHAT IS IT? A manual therapy which focuses on the musculoskeletal system to treat disease. Osteopaths use a range of techniques to mobilise soft tissues, bones and joints. Osteopathy and chiropractic therapy have much in common, but there are also important differences.

Osteopaths tend to use gentler techniques and often employ massage-like treatments. They also place less emphasis on the spine than chiropractors, and they rarely move the vertebral joints beyond their physical range of motion, unlike chiropractors. Therefore osteopathic interventions are less likely to injure.

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In general they treat mainly musculoskeletal problems, but many also claim to treat other conditions such as asthma, ear infection and colic.

DOES IT WORK? There is reasonably good evidence that the osteopathic approach is as effective as conventional treatments for back pain, but there is no good evidence to support the use of osteopathy in nonmusculoskeletal conditions.

People with severe osteoporosis, bone cancer, infections of the bone or bleeding problems should confirm with the osteopath that they will not receive forceful manual treatments.

LOOK BEFORE YOU LEAP:-


*Advice for anyone considering alternative medicine:

*Consult and inform your GP — the treatment might interfere with any ongoing conventional therapies.

*Do not stop your conventional treatment unless your doctor advises that this is sensible.

*Alternative therapies can be expensive, so make sure there is evidence to support the efficacy of a therapy before spending huge sums of money.

*Every treatment carries risks, so make sure the risks are outweighed by the benefits.

Sources: THe Telegraph (Kolkata, India)

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