Categories
News on Health & Science

Brain’s Role in Autism Probed

[amazon_link asins=’B01N3P7CFS,1935274651,B073XQSH2M,0986183563,B06XRZ3PFZ,B06XSBZQ6N’ template=’ProductCarousel’ store=’finmeacur-20′ marketplace=’US’ link_id=’01c39d12-d3f3-11e7-9119-6535b1f1a857′]

A psychology researcher has pinpointed regions of the brain that are linked to “ritualistic repetitive behavior” in autistic children — the insatiable desire to rock back and forth for hours or to tirelessly march in place.

CLICK & SEE

Keith Shafritz, an assistant professor of psychology at Hofstra University on Long Island, compared brain images of autistic children with those of neurologically normal youngsters. He and collaborators at Duke University and the University of North Carolina in Chapel Hill used a form of magnetic resonance imaging to explore sites in the brain.

They reported their findings in the current issue of Biological Psychiatry.

Repetitive behavior is one of autism’s core traits. It has driven parents to extremes as they try to distract a child to engage in other activities.

Mapping the brain constitutes a journey into the inner labyrinths of a three-pound cosmos where countless frontiers have yet to be explored.

In children with autism, Shafritz found deficits in specific regions of the cerebral cortex, the outer layer of gray matter linked to all higher human functions, including repetitive behavior. He also mapped deficits in the basal ganglia, a region deep below the cerebral hemispheres.

“We like to think about the research process as discovering clues why people engage in certain behaviors,” Shafritz said. “We were able to identify a series of brain regions that showed diminished activity when people were asked to alter certain behaviors and were not able to do so.”

Autism is a neurodevelopmental disorder that is becoming a major public policy issue. Federal health officials estimate that it afflicts 1 in every 150 children, which affects not only families but communities.

School systems don’t have enough appropriately trained teachers. Social services departments are overwhelmed by parents who need support and respite care.

For clues to the disorder, some scientists are scanning the human genome for suspect DNA.

Others, like Shafritz, are exploring the geography of the brain.

Edward G. Carr, a psychology professor at Stony Brook University in New York, said Shafritz’s discovery was important because it helped demystify repetitive behavior.

“Repetitive behavior is sometimes called self-stimulatory behavior. A very common form of it is body-rocking. A child will do it for hours,” Carr said. “Another child may wave his or her hands back and forth in front of their eyes. This is very common, and it’s called hand-flapping. They extend their arms forward and wave their hands in front of them. It’s like a light show.”

Shafritz said the brain areas associated with repetitious behavior were not associated with another autism problem, self-injury. Some children repeatedly slam their heads against a wall, for instance.

Still, Shafritz found a relationship between the newly identified brain areas and overlapping regions linked to schizophrenia, obsessive compulsive disorder and attention-deficit hyperactivity disorder.

Dr. Anil K. Malhotra, director of psychiatric research at Zucker Hillside Hospital in Glen Oaks, N.Y., said he was not surprised. He too is studying links between autism and schizophrenia, and autism and obsessive-compulsive disorder.

Sources:Los Angles Times

Categories
WHY CORNER

Why Drunk People Take Risks

[amazon_link asins=’B074XCCY5T,B072FL53NC,B07CQ7C65P,B07D3CZ9RK,B07CQ5K4W7,B00WH05GNW,B00KN12NEW,1520420587,B07F784R4Y’ template=’ProductCarousel’ store=’finmeacur-20′ marketplace=’US’ link_id=’eeb99cfe-8b56-11e8-a054-074cc0ba29b8′]

New brain imaging research shows that social drinkers have decreased sensitivity in brain regions involved in detecting threats, and increased activity in brain regions involved in reward.

CLICK & SEE

After alcohol exposure, threat-detecting brain circuits can’t tell the difference between a threatening and a non-threatening social situation.

Working with 12 healthy participants who drink socially, researchers used functional magnetic resonance imaging (fMRI) to study activity in emotion-processing brain regions during alcohol exposure. When participants received a placebo instead of alcohol, they showed greater activity in the amygdala, insula, and parahippocampal gyrus — brain regions involved in fear and avoidance — when shown a picture of a fearful facial expression.

Alcohol, meanwhile, activated striatal areas of the brain that are important components of the reward system, but did not increase brain activity in areas involved in fear.

.
Sources:

* Science Daily April 30, 2008

* The Journal of Neuroscience April 30, 2008

Categories
Healthy Tips

Sitting Straight ‘Bad for Backs’

[amazon_link asins=’B077N8TX6M,B01EVOJ51A,B019Z2UWQK,B075WPDP9Z,B074KF366L,B075YPM5V5,B0776MN1XL,B01IWM6056,B078XPZZ23′ template=’ProductCarousel’ store=’finmeacur-20′ marketplace=’US’ link_id=’7a23a78d-21c9-11e8-b243-91cfca0a4799′]

Sitting up straight is not the best position for office workers, a study has suggested.

CLICK  & SEE

Scottish and Canadian researchers used a new form of magnetic resonance imaging (MRI) to show it places an unnecessary strain on your back

They told the Radiological Society of North America that the best position in which to sit at your desk is leaning slightly back, at about 135 degrees.

Experts said sitting was known to contribute to lower back pain.

Data from the British Chiropractic Association says 32% of the population spends more than 10 hours a day seated

Half do not leave their desks, even to have lunch.

Two thirds of people also sit down at home when they get home from work.

Spinal angles

The research was carried out at Woodend Hospital in Aberdeen, Scotland.

Twenty two volunteers with healthy backs were scanned using a positional MRI machine, which allows patients the freedom to move – so they can sit or stand – during the test.

“Our bodies are not designed to be so sedentary” says Rishi Loatey, British Chiropractic Association

Traditional scanners mean patients have to lie flat, which may mask causes of pain that stem from different movements or postures.

In this study, the patients assumed three different sitting positions: a slouching position, in which the body is hunched forward as if they were leaning over a desk or a video game console, an upright 90-degree sitting position; and a “relaxed” position where they leaned back at 135 degrees while their feet remained on the floor.

The researchers then took measurements of spinal angles and spinal disk height and movement across the different positions.

Spinal disk movement occurs when weight-bearing strain is placed on the spine, causing the disk to move out of place.

Disk movement was found to be most pronounced with a 90-degree upright sitting posture.

It was least pronounced with the 135-degree posture, suggesting less strain is placed on the spinal disks and associated muscles and tendons in a more relaxed sitting position.

The “slouch” position revealed a reduction in spinal disk height, signifying a high rate of wear and tear on the lowest two spinal levels.

When they looked at all test results, the researchers said the 135-degree position was the best for backs, and say this is how people should sit.

‘Tendency to slide’

Dr Waseem Bashir of the Department of Radiology and Diagnostic Imaging at the University of Alberta Hospital, Canada, who led the study, said: “Sitting in a sound anatomic position is essential, since the strain put on the spine and its associated ligaments over time can lead to pain, deformity and chronic illness.”

Rishi Loatey of the British Chiropractic Association said: “One in three people suffer from lower back pain and to sit for long periods of time certainly contributes to this, as our bodies are not designed to be so sedentary.”

Levent Caglar from the charity BackCare, added: “In general, opening up the angle between the trunk and the thighs in a seated posture is a good idea and it will improve the shape of the spine, making it more like the natural S-shape in a standing posture.

“As to what is the best angle between thigh and torso when seated, reclining at 135 degrees can make sitting more difficult as there is a tendency to slide off the seat: 120 degrees or less may be better.”

You may click to see also:->Why back pain is hard to beat

Research finds knack to bad backs

Bed back pain theory thrown out

Office workers risk back strain
School books – a pain in the back

Women ‘putting up with back pain’

Back Car

Sources: BBC NEWS:

Categories
Ailmemts & Remedies

Frozen Shoulder

[amazon_link asins=’B017AD9B9K,1612436439,B071149H43,1452510725,1569757380,157224447X,B01MQUF0O4,B000BF70RA,B06XY58F5T’ template=’ProductCarousel’ store=’finmeacur-20′ marketplace=’US’ link_id=’8492b58a-e549-11e7-868d-157bdd34ede3′]

Frozen shoulder, medically referred to as adhesive capsulitis, is a disorder in which the shoulder capsule, the connective tissue surrounding the glenohumeral joint of the shoulder, becomes inflamed and stiff. Movement of the shoulder is severely restricted. The condition is sometimes caused by injury that leads to lack of use due to pain but also often arises spontaneously with no obvious preceding trigger factor. These seemingly spontaneous cases are usually referred to as Idiopathic Frozen Shoulder. Rheumatic disease progression and recent shoulder surgery can also cause a pattern of pain and limititation similar to frozen shoulder. Intermittent periods of use may cause inflammation.

You may click  to see the pictures

 

Abnormal bands of tissue (adhesions) grow between the joint surfaces, restricting motion. There is also a lack of synovial fluid, which normally helps the shoulder joint move by lubricating the gap between the humerus (upper arm bone) and the socket in the scapula (shoulder blade). It is this restricted space between the capsule and ball of the humerus that distinguishes adhesive capsulitis from a less complicated, painful, stiff shoulder. People with diabetes, stroke, lung disease, rheumatoid arthritis, and heart disease, or who have been in an accident, are at a higher risk for frozen shoulder. Adhesive capsulitis has been indicated as a possible adverse effect of some forms of highly active antiretroviral therapy (HAART). The condition rarely appears in people under 40 years old and (at least in its idiopathic form) is much more common in women than in men. Frozen shoulder in diabetic patients is generally thought to be a more troublesome condition than in the non-diabetic population. If a diabetic patient develops frozen shoulder then the time to full recovery is often prolonged.

Causes:
There are several different causes of a frozen shoulder. Some are obvious, whereas the others are difficult to find. A history of a fracture, a previous dislocated shoulder, or other trauma to the shoulder, can often aggravate the process of scar tissue formation. This is often made much worse by a period of prolonged immobilization in which the arm is held in a sling — a measure that is often necessary as a fracture heals or because pain from the original trauma limits motion. Loss of motion can also commonly occur as the result of a prior shoulder surgery for the treatment of other conditions — such as fractures or a torn rotator cuff.

The term “idiopathic adhesive capsulitis” is used to describe the gradual loss of shoulder motion which has no obvious cause or explanation. The reasons why this process occurs are unknown and are still the subject of debate among orthopedic surgeons. It is known that people with diabetes, neurologic illnesses, and other forms of inflammatory arthritis are at increased risk of developing a frozen shoulder. In general, this is a self-limiting disease, which means that over the course of several years it should run its course and then resolve itself. When there is no objective evidence of an obvious cause of a frozen shoulder (such as a prior fracture), then the first step in restoring motion is a program of supervised physical therapy in combination with a home program of maintenance exercises.

Signs and diagnosis:
With a frozen shoulder, one sign is that the joint becomes so tight and stiff that it is nearly impossible to carry out simple movements, such as raising the arm. People complain that the stiffness and pain worsen at night. Pain due to frozen shoulder is usually dull or aching. It can be worsened with attempted motion. A doctor, or therapist (occupational, massage or physical), may suspect the patient has a frozen shoulder if a physical examination reveals limited shoulder movement. Frozen shoulder can also be diagnosed if limits to the active range of motion (range of motion from active use of muscles) are the same or almost the same as the limits to the passive range of motion (range of motion from a person manipulating the arm and shoulder). An arthrogram or an MRI scan may confirm the diagnosis – although in practice this is rarely required. Most orthopaedic specialists make the diagnosis of frozen shoulder by recognising the typical pattern of signs and symptoms.

Physicians have described the normal course of a frozen shoulder as having three stages:

Stage one: In the “freezing” or painful stage, which may last from six weeks to nine months, the patient has a slow onset of pain. As the pain worsens, the shoulder loses motion.

Stage two: The “frozen” or adhesive stage is marked by a slow improvement in pain, but the stiffness remains. This stage generally lasts four months to nine months.

Stage three: The “thawing” or recovery, during which shoulder motion slowly returns toward normal. This generally lasts five months to 26 months.

Modern Treatment:
The natural course of a frozen shoulder can be separated into a few different phases. The first phase can be considered the “inflammatory” phase, during which the shoulder is painful and becomes less mobile. In the second phase, the shoulder is stiff, but the pain gradually decreases. In the third phase of “resolution”, the motion gradually improves in the shoulder. The natural course of this disorder can be very long, and the goals of treatment are to speed you towards the “resolution” phase faster.

A supervised physical therapy program can be successful in helping improve the shoulder pain and limited motion of the frozen shoulder. Physical therapy is more often successful in people who suffer from “idiopathic” adhesive capsulitis, and it allows them to gain a lot more use and function from their shoulder. Unfortunately, this approach is less successful in the treatment of shoulder problems after a previous surgery or a bad injury.

Because there is some scientific evidence that inflammation of the shoulder joint is one of the causes of a frozen shoulder, many doctors will inject the shoulder joint in order to calm the inflammation down. This injection uses a long acting local anesthetic like the Xylocaine® that the dentist uses and a powerful anti-inflammatory steroid as well. This is a very safe procedure, it is not terribly painful, and sometimes a single shot can make a very significant difference in the amount of shoulder pain and motion. The reason that an injection is more effective than oral medications is that it allows doctors to deliver a higher concentration of a more powerful anti-inflammatory medication to the inflamed tissues. If these treatments prove to be unsuccessful after a period of several months, then there are several options. The first option after these measures have failed is for a doctor to perform manipulation under general anesthesia.

Manipulation under anesthesia and What happens if this doesn’t work?

Shoulder Surgery Explained

Alternative Medication:

Zenotin: Simple time tested natural medicine as remedy for Frozen Shoulder

Treatment of Frozen Shoulder Using Chinese Medicine

Exercise program by physical therapist to treat frozen shoulder

Self-Treatment of Frozen Shoulder

Prevention:
To prevent the problem, a common recommendation is to keep the shoulder joint fully moving to prevent a frozen shoulder. Often a shoulder will hurt when it begins to freeze. Because pain discourages movement, further development of adhesions that restrict movement will occur unless the joint continues to move full range in all directions (adduction, abduction, flexion, rotation, and extension). Therapy will help one continue movement to discourage freezing and warm it. A medical doctor referral is needed before occupational or physical therapy can begin under law in most US states. Medical referral is not required for physical or occupational therapy in most Canadian provinces.

Management:
Management of this disorder focuses on restoring joint movement and reducing shoulder pain. Usually, it begins with nonsteroidal anti-inflammatory drugs (NSAIDs) and the application of heat, followed by gentle stretching exercises. These stretching exercises, which may be performed in the home with the help of a physical, massage or occupational therapist, are the treatment of choice. In some cases, transcutaneous electrical nerve stimulation (TENS) with a small battery-operated unit may be used to reduce pain by blocking nerve impulses.

One of the most successful treatments for frozen shoulder has been shown to be The Bowen Technique with average range of motion improvement of 23° during controlled trials.

If these measures are unsuccessful, the doctor may recommend manipulation of the shoulder under general anesthesia to break up the adhesions. Surgery to cut the adhesions is only necessary in some cases.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Resources:
http://en.wikipedia.org/wiki/Frozen_shoulder
http://www.shouldersolutions.com/frozen_2.php

 

Enhanced by Zemanta
Categories
Ailmemts & Remedies

Vertigo

Vertigo, a specific type of dizziness, is a major symptom of a balance disorder. It is the sensation of spinning or swaying while the body is stationary with respect to the earth or surroundings. There are two types of vertigo: subjective and objective. A person experiencing subjective vertigo feels a false sensation of movement. When a person experiences objective vertigo, the surroundings will appear to move past his or her field of vision.

The effects of vertigo may be slight. It can cause nausea and vomiting and, if severe, may give rise to difficulty with standing and walking.

The word “vertigo” comes from the Latin “vertere”, to turn + the suffix “-igo”, a condition = a condition of turning about.

CLICK & SEE THE PIICTURES

Causes of vertigo
Vertigo is usually associated with a problem in the inner ear balance mechanisms (vestibular system), in the brain, or with the nerve connections between these two organs.

The most common cause of vertigo is benign paroxysmal positional vertigo, or BPPV. Vertigo can be a symptom of an underlying harmless cause, such as in BPPV or it can suggest more serious problems. These include drug toxicities (specifically gentamicin), strokes or tumors (though these are much less common than BPPV).

Vertigo can also be brought on suddenly through various actions or incidents, such as skull fractures or brain trauma, sudden changes of blood pressure, or as a symptom of motion sickness while sailing, riding amusement rides, airplanes or in a vehicle.

Vertigo-like symptoms may also appear as paraneoplastic syndrome (PNS) in the form of opsoclonus myoclonus syndrome. A multi-faceted neurological disorder associated with many forms of incipient cancer lesions or virus. If conventional therapies fail, consult with a neuro-oncologist familiar with PNS.

Vertigo is typically classified into one of two categories depending on the location of the damaged vestibular pathway. These are peripheral or central vertigo. Each category has a distinct set of characteristics and associated findings.

Peripheral vertigo
The lesions, or the damaged areas, affect the inner ear or the vestibular division of the auditory nerve or (Cranial VIII nerve). Vertigo that is peripheral in origin tends to be felt as more severe than central vertigo, intermittent in timing, always associated with nystagmus in the horizontal plane and occasionally hearing loss or tinnitus (ringing of the ears).

Peripheral vertigo can be caused by BPPV, labyrinthitis, Ménière’s disease, perilymphatic fistula or acute vestibular neuronitis. Peripheral vertigo, compared to the central type, though subjectively felt as more severe, is usually from a less serious cause.

Central vertigo
The lesions in central vertigo involve the brainstem vestibulocochlear nerve nuclei. Central vertigo is typically described as constant in timing, less severe in nature and occasionally with nystagmus that can be multi-directional. Associated symptoms include motor or sensory deficits, dysarthria (slurred speech) or ataxia.

Causes include things such as migraines, multiple sclerosis, posterior fossa tumors, and Arnold-Chiari malformation. Less commonly, strokes (specifically posterior circulation stroke), seizures, trauma (such as concussion) or infections can also cause central vertigo.

Vertigo in context with the cervical spine
According to chiropractors, ligamental injuries of the upper cervical spine can result in head-neck-joint instabilities which can cause vertigo.[citation needed] In this view, instabilities of the head neck joint are affected by rupture or overstretching of the alar ligaments and/or capsule structures mostly caused by whiplash or similar biomechanical movements.

Symptoms during damaged alar ligaments besides vertigo often are

dizziness

reduced vigilance, such as somnolence

seeing problems, such as seeing “stars”, tunnel views or double contures.

Some patients tell about unreal feelings that stands in correlation with:

depersonalization and attentual alterations

Medical doctors (MDs) do not endorse this explanation to vertigo due to a lack of any data to support it, from an anatomical or physiological standpoint. Often the patients are having an odyssey of medical consultations without any clear diagnosis and are then sent to psychiatrist because doctors think about depression or hypochondria. Standard imaging technologies such as CT Scan or MRI are not capable of finding instabilities without taking functional poses.

Neurochemistry of vertigo
The neurochemistry of vertigo includes 6 primary neurotransmitters that have been identified between the 3-neuron arc that drives the vestibulo-ocular reflex (VOR). Many others play more minor roles.

Three neurotransmitters that work peripherally and centrally include glutamate, acetylcholine, and GABA.

Glutamate maintains the resting discharge of the central vestibular neurons, and may modulate synaptic transmission in all 3 neurons of the VOR arc. Acetylcholine appears to function as an excitatory neurotransmitter in both the peripheral and central synapses. GABA is thought to be inhibitory for the commissures of the medial vestibular nucleus, the connections between the cerebellar Purkinje cells and the lateral vestibular nucleus, and the vertical VOR.

Three other neurotransmitters work centrally. Dopamine may accelerate vestibular compensation. Norepinephrine modulates the intensity of central reactions to vestibular stimulation and facilitates compensation. Histamine is present only centrally, but its role is unclear. It is known that centrally acting antihistamines modulate the symptoms of motion sickness.

The neurochemistry of emesis overlaps with the neurochemistry of motion sickness and vertigo. Acetylcholinc, histamine, and dopamine are excitatory neurotransmitters, working centrally on the control of emesis. GABA inhibits central emesis reflexes. Serotonin is involved in central and peripheral control of emesis but has little influence on vertigo and motion sickness.

Diagnostic testing
Tests of vestibular system (balance) function include electronystagmography (ENG), rotation tests, Caloric reflex test,[2] and Computerized Dynamic Posturography (CDP).

Tests of auditory system (hearing) function include pure-tone audiometry, speech audiometry, acoustic-reflex, electrocochleography (ECoG), otoacoustic emissions (OAE), and auditory brainstem response test (ABR; also known as BER, BSER, or BAER).

Other diagnostic tests include magnetic resonance imaging (MRI) and computerized axial tomography (CAT, or CT).

Treatment:

Treatment is specific for underlying disorder of vertigo.
Vestibular rehabilitation
anticholinergics
antihistamines
benzodiazepines
calcium channel antagonists, Specific Verapamil and Nimodipine
GABA modulators, specifically gabapentin and baclofen
Neurotransmitter reuptake inhibitors such as SSRI’s, SNRI’s and Tricyclics

Click to read : Benign paroxysmal positional vertigo (BPPV)

Vertigo: Its Causes and Treatment

Herbal Treatment:

THE HERBS listed below can help ease impaired sense of balance often described as “light-headedness” or “dizziness,” either of which can be symptoms of serious conditions, such as heart attack or stroke.

Butcher’s broom, cayenne 40,000 Scoville heat units, ginkgo biloba, coral calcium with trace minerals, kelp.

Quik Tip: Diminished blood flow to the brain can cause dizziness and lightheadedness, making circulatory stimulants like cayenne good choices for relief.

EXERCISE  TO  CURE VERTIGO

YOGA EXERCISES  FOR VERTIGO

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Resources:http://en.wikipedia.org/wiki/Vertigo_%28medical%29    http://www.herbnews.org/vertigodone.htm

Enhanced by Zemanta
css.php