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Top Eight Cancer Signs Pinpointed

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The eight unexplained symptoms most closely linked to cancer have been highlighted by researchers.

The Keele University team also points to the age at which patients should be most concerned by the symptoms, which include blood in urine and anaemia.

The other symptoms are: rectal blood, coughing up blood, breast lump or mass, difficulty swallowing, post-menopausal bleeding and abnormal prostate tests.

Eight signs of cancer:-
*Anaemia
*Blood in urine
*Coughing up blood
*Difficulty swallowing
*Breast lump or mass
*Post-menopausal bleeding
*Abnormal prostate test
*Rectal blood

There are more than 200 different types of cancer, which cause many different symptoms.

Cancer Research UK said unusual changes in a person’s health should be checked as early as possible.


Source
: BBC NEWS: 26th. Aug.2010

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Health Alert News on Health & Science

An Increase in Leptin Could Promote Colorectal Cancer

While researchers have known that obesity increases the risk for the development of colon cancer, the underlying molecular mechanisms have remained unclear.
…CLICK & SEE
Now, for the first time, researchers have found that an increase in leptin, a cytokine that is normally increased in obese or overweight individuals, may promote colorectal neoplasms by activating colorectal cancer stem cells.

Cancer stem cells constitute a small subfraction of tumor cells that are characterized by long lifespan and capacity for self-renewal, and are responsible for tumor development, resistance to treatments and cancer recurrence. In colon cancer, leptin is able to increase the growth, survival, and resistance to certain chemotherapy treatments in this key cell population.

Leptin, a fat tissue-derived pluripotent cytokine regulating appetite and energy balance in the brain, also controls many physiological and pathological processes in peripheral organs, including carcinogenesis.

Colon cancer has increased in developed countries, possibly due to sedentary lifestyles and high caloric diets. Prior research has linked obesity to colorectal cancer risk by .4-1.0 fold in men and up to 2.0 fold in premenopausal women.

“Since targeting cancer stem cells may be a translationally relevant strategy to improve clinical outcomes, interfering with leptin signaling by targeting leptin receptors might become a novel attractive option for colorectal cancer treatment, particularly in obese patients,” says senior author of the study, Eva Surmacz.

“It is important to consider that cancer stem cells have been identified in several human malignancies,” says Monica Bartucci, study co-author. “Understanding how cancer stem cells interact with a tumor environment, including hormones like leptin, is likely to have significant implications for treatment management of different cancer types in human patients. We hope, in collaboration with Dr. Surmacz, not only to test the effects of leptin antagonist compounds on colon cancer stem cells but also to study the results of leptin stimulation on cancer stem cells isolated in other cancer tissues.”

Source: Elements4Health

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Health Alert

Morning Sickness, All Day Long

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Pregnancy sometimes causes nausea and vomiting. It is dismissed as normal morning sickness. In some cultures, vomiting is actually taken as proof of pregnancy.
…..CLICK & SEE
Morning sickness, however, is not necessarily confined to the morning, though 80 per cent of pregnant women fall in this category
. It can occur at any time of the day or night. The remaining 20 per cent of the women may show other signs of pregnancy such as eating ravenously.

Vomiting usually starts around the sixth week — around two weeks after the period is missed. It settles around the twelfth week, and then disappears around the fifth month. Any strong smell can precipitate waves of nausea — be it garbage or spices being fried in the kitchen.

Baffled scientists put forward many theories to explain this strange phenomenon. It was touted as an unconscious rejection of the pregnancy. Women were unsympathetically told to “control themselves”. Some blamed it on the hormonal changes during the period, which causes relaxation of the smooth muscles of the oesophagus and gall bladder and slows digestion.

Scientists have now discovered that the nausea is due to sensitivity to a hormone called HCG (human chorionic gonadotrophin). The vomiting coincides with peak levels of this hormone (six to 12 weeks).

The sensitivity varies and is genetically determined. Women who vomit during pregnancy often have mothers and sisters who had the same problem. It also tends to recur in each succeeding pregnancy, though, if the tolerance levels to HCG build up, the vomiting in the second pregnancy can be less than that in the first.

Excessive vomiting causes 1 per cent of the women who vomit to become morbidly ill. They lose 5 per cent or more of their pre-pregnancy weight. The violent retching can cause tears in the esophagus, resulting in blood in the vomit. The inability to retain any food in the stomach can result in dehydration severe enough to affect the kidneys. Blood may begin to clot in the veins. The brain may be affected as a result of electrolyte imbalance or dehydration. Loss of vitamins, particularly thiamine, may cause delirium.

This severe vomiting is also known as hyperemesis gravidarum (in Latin, gravid means pregnant, and hyper is excessive). It is more likely in younger women who are underweight before the pregnancy, pre-diabetic (abnormal GTT values) or have migraine headaches.

Persistent hyperemesis can be a danger signal. It can occur if the levels of HCG are higher than normal. This occurs when it is a twin pregnancy or if the baby has a chromosomal abnormality like trisomy 18 or 21. Or, it may not be a pregnancy at all but a tumour called hydatidiform mole that mimics pregnancy. An ultrasound examination at this stage will pick up all the above abnormalities.

Well meaning advice to tackle morning sickness with bed rest is counterproductive. The reclining position may further aggravate reflux from the stomach. Moreover, inactivity may lead to loss of muscle mass. This may make it difficult to withstand the rigours of labour and childbirth.

• To tackle morning sickness, consider the following.

• A good diet with adequate vitamins, particularly folic acid.

• Exposure to fresh air. Try going for a walk outdoor for half an hour in the morning and evening.

• Eat several small meals instead of three regular ones.

• Avoid anything that triggers the vomiting even if it touted as being “good for the baby”.

Ginger helps as lozenges, ginger tea or lime juice. Supplements are available but since the other additives in the capsules are not known, it is probably better and safer to use the natural product.

Peppermint can be sucked as lozenges or peppermint oil used as inhalations.

Try acupressure. The pressure point to reduce nausea is located in the middle of the inner wrist, three finger-breadths away from the crease and between the two tendons. Locate and press firmly, one wrist at a time for three minutes.

Despite this, if uncontrollable vomiting occurs, with aversion to food, loss of weight, dark coloured urine, loss of consciousness, headache, confusion or fainting, it is better to seek medical help. Hyperemesis can be fatal.

An initial evaluation will rule out a correctable cause like a urinary tract infection, acid dyspepsia, chromosomal abnormalities or a hydatidiform mole. Intravenous fluids (IV) can be given to restore hydration, electrolytes, vitamins and nutrients.

If anti-nausea medications are used, the danger to the baby has to be weighed against the risk to the mother. Strict medical supervision and documentation of the dose and duration of treatment are required.

Source : The Telegraph ( Kolkata, India)

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Health Alert

The 9 Worst Places for Your Health

MSNBC lists some surprisingly bad locations for your health, and the best places to optimize it:

1.Worst place to keep your toothbrush — the bathroom sink

CLICK & SEE
There are 3.2 million microbes per square inch in the average toilet bowl, and all of those germs are propelled out every time you flush, settling on the floor and the sink. Keep your toothbrush behind closed doors in the medicine cabinet or a nearby cupboard.

2.Worst place to stash sneakers and flip-flops — the bedroom closet

CLICK & SEE

Shoes track in allergens and contaminants. Leave your shoes by the front door.

3.Worst place to fall asleep — under piles of blankets..CLICK & SEE

Being overheated can keep you from sleeping. Let your feet stick out from under your blankets.

4.Worst place to cool leftovers — in the refrigerator...CLICK & SEE

Placing hot leftovers directly in the fridge can cause uneven cooling and possibly food poisoning. Leave food to cool on the counter for up to an hour after cooking, or divide it into smaller containers that can cool faster before refrigerating.

5.Worst place to sit on an airplane — the rear….CLICK & SEE

The tail of the plane is where you’ll get the bumpiest ride. Sit as close to the wing as you can.

6.Worst place to set your handbag — the kitchen counter….....CLICK & SEE

Tests have showed up to 10,000 bacteria per square inch on purse bottoms. Put your bag anywhere except where food is prepared or eaten.

7.Worst place to use a public bathroom — the stall in the middle...CLICK & SEE
The center stall has more bacteria. Pick a stall all the way left or right.

8.Worst place to keep medicine — the medicine cabinet  in the bathroom...CLICK & SEE
The temperature in a bathroom can get well above the recommended storage temperatures for many common drugs. Keep medicine somewhere cool and dry, such as the pantry.

9.Worst place to use headphones — on an airplane, train, or subway…CLICK & SEE

You’re probably turning the volume up too high if you’re listening to headphones in a noisy environment. Listen wherever you don’t have to blast your music to enjoy it, or consider using noise-canceling headphones.

You may click to see:->

*8 Spots Germs Love to Lurk in Your Home
*Does Your Home Harbor Safety Hazards?
*How to Avoid the Top 5 Deadliest Household Tragedies

Source: MSNBC June 8, 2010

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Health Alert News on Health & Science

New Study Shows Profound Impact of Anger on Your Health

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When you get angry, your heart rate, arterial tension and testosterone production increases, cortisol (the stress hormone) decreases, and the left hemisphere of your brain becomes more stimulated.

…………...click & see.

Researchers induced anger in 30 men “Anger Induction” (AI), which consists of 50 phrases in first person that reflect daily situations that provoke anger.

Before and immediately after the inducement of anger, the researchers measured heart rate and arterial tension, levels of testosterone and cortisol, and the asymmetric activation of the brain.

According to Eurekalert:
“The results … reveal that anger provokes profound changes in the state of mind of the subjects (‘they felt angered and had a more negative state of mind’) and in different psychobiological parameters.”

Resources:
Eurekalert May 31, 2010
Hormones and Behavior March 2010, 57(3):276-83

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