Tag: Blood sugar

Categories
News on Health & Science

Sweet Drag

T.V. Jayan on a new study that confirms that nicotine worsens diabetes-related complications

click to see
If you are diabetic and also enjoy your smoke, it’s a double whammy for you. Diabetic smokers will find it difficult to stave off complications associated with rising blood sugar levels, new research has shown.

The study — by Xian-Chuan Liu, a researcher at the California State Polytechnic University in the US — is the first to establish a strong link between smoking and diabetes-related complications. The work was presented at the 241st annual meeting of the American Chemical Society in Anaheim yesterday. “If you’re a smoker and have diabetes, you should be concerned and make every effort to quit smoking,” says Liu.

Though cigarette smoking is a major health risk factor that significantly increases your chances of heart disease, cancer, and acute and chronic respiratory tract infection, it was hardly implicated in the development of diabetes till very recently. One study in the recent past, however, showed that smokers may be nearly 50 per cent more vulnerable to developing type 2 diabetes than non-smokers. Similarly, children born to smoking mothers will have impaired production of insulin, the hormone required to regulate glucose uptake by cells, and thus may develop type 1 diabetes.

The new study has gone a step further to show that smoking worsens the complications associated with diabetes and how this really happens. Some of the complications linked to diabetes are heart attack, stroke, kidney failure and nerve damage.

According to the Brussels-based International Diabetes Federation, more than 300 million people around the world suffer from diabetes. The figure is expected to reach close to 500 million by 2030.

The study is particularly significant for India, where a large number of diabetics are also smokers. It is estimated that there are more than 50 million diabetics in the country. A study published in the New England Journal of Medicine in 2008 showed that India is home to more than 120 million smokers.

Though doctors have known for years that smoking increases the risk of developing diabetes-related complications, they haven’t been able to pinpoint the exact substance in cigarette smoke responsible for this. Liu and his colleagues suspected it may be nicotine, the chemical that makes smoking addictive.

As diabetes has no cure yet, the only way to ward off complications is to maintain the required blood sugar levels through medicine and lifestyle modification. The gold standard for monitoring long-term blood sugar levels in diabetics is a blood test called the haemoglobin A1c (HbA1c).

The premise for the HbA1c test is as follows. The haemoglobin in red blood cells reacts with glucose molecules to form what is called glycated haemoglobin. In individuals with poorly controlled diabetes, the quantities of these glycated haemoglobins are much higher than in healthy people. Hence, the number of glycated haemoglobins in one’s blood gives a fairly accurate measure of glucose levels in blood.

Used often in conjunction with regular blood sugar monitoring, the HbA1c test reveals the average amount of sugar in blood during a period of up to three months. High HbA1c test results mean that the condition is not well controlled and there is an increased risk of chronic complications.

To explore their theory that nicotine has a role, the scientists set out to check how the chemical influences HbA1c. Using human blood samples, they showed that concentrations of nicotine similar to those found in the blood of smokers did, indeed, raise levels of HbA1c.

“Nicotine caused HbA1c levels to rise by as much as 34 per cent,” Liu told Knowhow. In moderate smokers, the increase was about 10 per cent.

“This looks like an important finding. We had so far thought that nicotine had no influence on diabetes-related complications,” says Balbir Singh, cardiologist at Medanta, a private hospital in Gurgaon.

High blood sugar or not, it doesn’t matter. Stub out that cigarette in any case.

Source: The Telegraph ( Kolkata, India)

Related articles
Enhanced by Zemanta
Categories
News on Health & Science

Freedom From the Daily JAB

[amazon_link asins=’B01BURN526,B01N0SA79U,B01JXP3BHQ,B072JXCRGD,B002CPXTBI,B07497KJ1S,B01N1TSIX3′ template=’ProductCarousel’ store=’finmeacur-20′ marketplace=’US’ link_id=’0c611da5-db5a-11e7-adeb-a7135be59b3b’]

Indian scientists are using tissue engineering to give diabetes patients new insulin-making cells……...CLICK & SEE

Biomaterials scientist Prabha Nair is pitting her expertise of polymers to hold out a new line of hope for patients with diabetes who are dependent on insulin shots. In her laboratory, she has used two structures fashioned out of polymer materials to normalise blood sugar in rats with diabetes for up to 90 days. One of the polymer structures is designed to make insulin-secreting cells function properly, while the other is intended to protect such cells from threats that might emerge from the body’s immune system.

Nair and her colleagues at the government-funded Sree Chitra Tirunal Institute of Medical Sciences and Technology (SCTIMST), Thiruvananthapuram have combined two applications of polymers to tackle two major obstacles that have held back a promising but experimental treatment for diabetes from widespread use. The treatment, called islet cell transplantation, involves the removal of insulin-secreting cells from the pancreas of a deceased organ donor and their implantation into a patient with diabetes.

It is nearly a decade since researchers at the University of Alberta in Edmonton, Canada, demonstrated that islet cell transplantation may help patients with diabetes acquire normal blood sugar levels and achieve some level of freedom from the need for insulin.

A review of islet transplantation on 225 patients between 1999 and 2006 had revealed several benefits — including reduced need for insulin, improved blood glucose control, and lowered risk of hypoglycemia, according to the National Institute of Diabetes and Digestive and Kidney Disorders in the US. Two years after the islet transplantation, about one-third of the recipients were free of the need for insulin shots, the review suggested.

Islet cell transplantation, however, is not standard therapy yet. “There is a critical shortage of islet cells because of a shortage of organ donors,” says Nair, a scientist in the division of tissue engineering and regeneration technologies at the SCTIMST.

Patients who receive islet cells need to take immunosuppressive drugs throughout their lives to prevent their immune systems from destroying the implanted cells. These drugs have side effects including an increased risk of cancer.

The SCTIMST researchers harvested a class of cells known as pancreatic progenitor cells from mice and placed them in a cocktail of appropriate biochemicals where they turn into insulin-secreting islet-like cells.

The scientists then loaded these islet-like cells into three-dimensional scaffolds constructed out of a gelatin, a natural polymer, and polyvinylpyrrolidone, a synthetic polymer. The islet-like cells proliferate on the scaffolds and serve as a potential source of insulin.

In experiments, the scientists observed that rats with diabetes that received these islet cell-bearing scaffolds alone died within 20 days. Their scaffold cells had been attacked by the rats’ immune systems, leading to the destruction of tissue and the failure of the implantation.

“We also designed a polymer capsule to shield the implanted islet cells from the immune system,” Nair told KnowHow. When the scientists combined the scaffolding, also called tissue engineering, with encapsulation, the rats survived for up to 90 days.

The rats were models for type-I, or insulin-dependent diabetes, but researchers say the tissue engineering and encapsulation strategy may also be considered as a possible option for patients with adult-onset diabetes who need insulin injections. Given the differences in the lifespans of rats and humans, some researchers believe the 90-day freedom from insulin observed in the laboratory animals may be equivalent to several years in humans — although exactly how long is still a subject of debate.

“These results are really exciting,” says Aroop Dutta, a tissue engineering specialist and founder of ExCel Matrix Biologicals, a Hyderabad-based start-up in biomaterials and tissue engineering, who was not connected with the research in Thiruvananthapuram.

“There just aren’t enough human-derived islet cells for the large numbers of diabetes patients dependent on insulin. Animal cells or stem cell-based approaches are the only viable options as sustained sources of islet cells,” he adds.

The results of the SCTIMST’s experiments were published last Friday in the journal Acta Biomaterialia. The researchers say their use of islet cells from mice in rats with diabetes suggests that the polymer capsule that keeps the immune system at bay may facilitate xenotransplants — the use of cells or organs across species — as an option for reversing diabetes. “But there is still much work to be done,” Nair cautions.

“We’ll need to establish that this also works in large animals,” she said. The SCTIMST group plans to initiate studies in pigs with diabetes. If the technique is indeed shown to work in large animals too, it could be ready for human clinical trials within two or three years.

Source : The Telegraph ( kolkata, India)

Related articles
Enhanced by Zemanta
Categories
Herbs & Plants Lentils

Cajanus cajan (Pegion pea)

Botanical Name :Cajanus cajan (Linn) Millsp.
Other scientific names:  Cystisus cajan, Cystisus pseudo-cajan  ,Cajan inodorum  ,Cajanus bicolor,Cajanus indicus
Family :Fabaceae

Genus: Cajanus
Species: C. cajan
Kingdom: Plantae
Division: Magnoliophyta
Class: Magnoliopsida
Order: Fabales

Synonyms:Cajanus indicus Spreng. (Valder 1895) and Cytisus cajan (Crawfurd 1852)

Common Names :Arhar, Red gram, Pigeon pea, Gablos (Tag.) ,Kadios (Mang., Tag., P. Bis.) ,Kagyos (Tag.) ,Kaldis (Ig., Ilk.)   Kagyas (Tag.) ,Kalios (Tag.) , Kardis (Ibn., Ilk., Ig.) ,Kidis (Ilk., Bon.) ,Kusia (Ig., If.) , Tabios (Bik., C. Bis.) ,Guandu (Brazil) .Pigeon pea (Engl.),toor dal or arhar dal (India), Congo pea or gungo pea (in Jamaica), Pois Congo (in Haiti), gandul (in Puerto Rico), gunga pea, or no-eye pea.   arhar dal  in Bengali


Habitat : Probably native to India, pigeon pea was brought millennia ago to Africa where different strains developed. These were brought to the new world in post-Columbian times. Truly wild Cajanus has never been found; they exist mostly as remnants of cultivations. In several places Cajanus persists in the forest. The closest wild relative, Atylosia cajanifolia Haines, has been found in some localities in East India. Most other Atylosias are found scattered throughout India, while in North Australia a group of endemic Atylosia species grow. In Africa Cajanus kerstingii grows in the drier belts of Senegal, Ghana, Togo, and Nigeria. Pigeon peas occur throughout the tropical and subtropical regions, as well as the warmer temperate regions (as North Carolina) from 30°N to 30°S (Duke, 1981a). In settled areas throughout the Philippines: cultivated, semicultivated, and in some places, spontaneous.

Description:

It is  is a perennial herb.An erect, branched, hairy shrub, 1-2 meters high. Leaves are oblong-lanceolate to oblanceolate with three leaflets. Flowers are yellow, in sparse peduncled racemes, about 1.5 cm long. Pod is hairy, 4-7 cm long, 1 cm wide, containing 2-7 seeds.

CLICK TO SEE THE PICTURES…>..(0).….(01).….(1)..…....(2)..…...(3).…..(4).….…(5).…….(6)...

Cultivation:
The cultivation of the pigeon pea goes back at least 3000 years. The centre of origin is most likely Asia, from where it traveled to East Africa and by means of the slave trade to the American continent. Today pigeon peas are widely cultivated in all tropical and semi-tropical regions of both the Old and the New World. Pigeon peas can be of a perennial variety, in which the crop can last 3–5 years (although the seed yield drops considerably after the first two years), or an annual variety more suitable for seed production.

Pigeon peas are an important legume crop of rainfed agriculture in the semi-arid tropics. The Indian subcontinent, Eastern Africa and Central America, in that order, are the world’s three main pigeon pea producing regions. Pigeon peas are cultivated in more than 25 tropical and sub-tropical countries, either as a sole crop or intermixed with cereals such as sorghum (Sorchum bicolor), pearl millet (Pennisetium glaucum), or maize (Zea mays), or with other legumes, such as peanuts (Arachis hypogaea). Being a legume, the pigeon pea enriches soil through symbiotic nitrogen fixation.

The crop is cultivated on marginal land by resource-poor farmers, who commonly grow traditional medium- and long-duration (5–11 months) landraces. Short-duration pigeon peas (3–4 months) suitable for multiple cropping have recently been developed. Traditionally, the use of such input as fertilizers, weeding, irrigation, and pesticides is minimal, so present yield levels are low (average = 700 kg/ha). Greater attention is now being given to managing the crop because it is in high demand at remunerative prices.

Pigeon peas are very drought resistant and can be grown in areas with less than 650 mm annual rainfall.

World production of pigeon peas is estimated at 46,000 km2. About 82% of this is grown in India. These days it is the most essential ingredient of animal feed used in West Africa, most especially in Nigeria where it is also grown

Edible Uses: Vegetable food crop ( seeds and pods) in South-East Asia.Pigeon peas are both a food crop (dried peas, flour, or green vegetable peas) and a forage/cover crop. They contain high levels of protein and the important amino acids methionine, lysine, and tryptophan.  In combination with cereals, pigeon peas make a well-balanced human food. The dried peas may be sprouted briefly, then cooked, for a flavor different from the green or dried peas. Sprouting also enhances the digestibility of dried pigeon peas via the reduction of indigestible sugars that would otherwise remain in the cooked dried peas.

In India, split pigeon peas (toor dal) are one of the most popular pulses, being an important source of protein in a mostly vegetarian diet. In regions where it grows, fresh young pods are eaten as vegetable in dishes such as sambhar.

In Ethiopia, not only the pods but the young shoots and leaves are cooked and eaten.

CLICK  &  SEE  THE  PICTURES

In some places, such as the Dominican Republic and Hawaii, pigeon peas are grown for canning and consumption. A dish made of rice and green pigeon peas (called “Moro de Guandules”) is a traditional food in Dominican Republic. Pigeon peas are also made as a stew, with plantain balls. In Puerto Rico, arroz con gandules is made with rice and pigeon peas and is a typical dish.

In Thailand, pigeon peas are grown as a host for scale insects which produce lac.

Pigeon peas are in some areas an important crop for green manure, providing up to 40 kg nitrogen per hectare. The woody stems of pigeon peas can also be used as firewood, fencing and thatch.

Nutrition
Used mainly for its edible young pods and seeds.

Chemical constituents :
Roots are considered antihelminthic, expectorant, febrifuge, sedative, vulnerary.
Seeds are rich in carbohydrates (58%) and proteins (19%).
Fair source of calcium and iron; good source of vitamin B.
Chemical studies reveal: 2′-2’methylcajanone, 2′-hydroxygenistein, isoflavones, cajanin, cahanones, among many others.

Analysis of dhal (without husk) gave the following values: moisture, 15.2; protein, 22.3; fat (ether extract), 1.7; mineral matter, 3.6; carbohydrate, 57.2; Ca, 9.1; and P, 0.26%; carotene evaluated as vitamin A, 220 IU and vitamin B1, 150 IU per 100 g. Sun-dried seeds of Cajanus cajan are reported to contain (per 100 g) 345 calories, 9.9% moisture, 19.5 g protein, 1.3 g fat, 65.5 g carbohydrate, 1.3 g fiber, 3.8 g ash, 161 mg Ca, 285 mg P, 15.0 mg Fe, 55 mg b-carotene equivalent, 0.72 mg thiamine, 0.14 mg riboflavin, and 2.9 mg niacin. Immature seeds of Cajanus cajan are reported to contain per 100 g, 117 calories, 69.5% moisture, 7.2 g protein, 0.6 g fat, 21.3 g total carbohydrate, 3.3 g fiber, 1.4 g ash, 29 mg Ca, 135 mg P, 1.3 mg Fe, 5 mg Na, 563 mg K, 145 mg b-carotene equivalent, 0.40 mg thiamine, 0.25 mg riboflavin, 2.4 mg niacin, and 26 mg ascorbic acid/100 g. Of the total amino acids, 6.7% is arginine, 1.2% cystine, 3.4% histidine, 3.8% isoleucine, 7.6% leucine, 7.0% lysine, 1.5% methionine, 8.7% phenylalanine, 3.4% threonine, 2.2% tyrosine, 5.0% valine, 9.8 aspartic acid, 19.2% glutamic acid, 6.4% alanine, 3.6% glycine, 4.4% proline, 5.0% serine with 0 values for canavanine, citrulline and homoserine. Methionine, cystine, and tryptophane are the main limiting amino acids. However, in combination with cereals, as pigeon peas are always eaten, this legume contributes to a nutritionally balanced human food. The oil of the seeds contains 5.7% linolenic acid, 51.4% linoleic, 6.3% oleic, and 36.6% saturated fatty acids. Seeds are reported to contain trypsin inhibitors and chymotrypsin inhibitors. Fresh green forage contains 70.4% moisture, 7.1 crude protein, 10.7 crude fiber, 7.9 N-free extract, 1.6 fat, 2.3 ash. The whole plant, dried and ground contains 1,1.2% moisture, 14.8 crude protein, 28.9 crude fiber, 39.9 N-free extract, 1.7 fat, and 3.5 ash. (Duke, 1981a)

Medicinal Uses:
Parts used
Leaves, roots.

Folkloric:-
*Decoction or infusionn of leaves for coughs, diarrhea, abdominal pains.
*Tender leaves are chewed for aphthous stomatitis and spongy gums.
*Pulped or poulticed leaves used for sores.
*In Peru, leaves are used as an infusion for anemial, hepatitis, diabetes, urinary infections and yellow fever.
*In Argentina, leaves used for genital and skin problems; flowers used for bronchitis, cough and pneumonia.
*In China, as vermifuge, vulnerary; for tumors.
*In Panama, used for treatment of diabetes (See study below).
*In Indian folk medicine, used for a variety of liver disorders.



Other Uses:
As forage or hay.
Branches and stems for basket and fuel. (Source)

Often grown as a shade crop for tree crops or vanilla, a cover crop, or occasionally as a windbreak hedge. In Thailand and N. Bengal, pigeon pea serves as host for the scale insect which produces lac or sticklac. In Malagasy the leaves are used as food for the silkworm. Dried stalks serve for fuel, thatch and basketry. (Duke, 1981a).

Studies:-
• RBC Sickling Inhibition: StudyClinical studies have reported seed extracts to inhibit red blood cell sickling and potential benefit for people with sickle cell anemia.

• Antiplasmodial constituents of Cajanus cajan: Study isolated two stilbenes, longistylin A and C and betulinic acid from the roots and leaves of CC and showed moderately high in vitro activity against Plasmodium falcifarum strain.

• Stilbenes / Neuroprotective / Alzheimer’s Disease: Study of stilbenes containing extract-fraction from C cajan showed significant amelioration of cognitive deficits and neuron apoptosis. Findings suggest sECC has a potential in the development of therapeutic agent to manage cognitive impairment associated with Alzheimer’s disease through increase choline acetyltransferase activity and anti-oxidative mechanism.

• Hypocholesterolemic Effect: Study on the stilbenes containing extract-fraction of CC showed a hypocholesterolemic effect possibly through enhancement of hepatic LDL-receptor and cholesterol 7-alpha-hydroxylase expression levels and bile acid synthesis.

• Hyperglycemic Effect: Evaluation of traditional medicine: effects of Cajanus cajan L. and of Cassia fistula L. on carbohydrate metabolism in mice: Contradicting its traditional use for diabetes, CC did not have a hypoglycemic effect on sugar, instead at higher doses, it produced a hyperglycemic effect.

• Antimicrobial: Study shows the organic solvent extracts to inhibit E coli, S aureus and S typhi and the aqueous extract were inhibitory to E coli and S aureus.

• Antimicrobial / Antifungal: Nigerian study on the antimicrobial effects of the ethanol and aqueous extracts of locally available plants, including C cajan, showerd inhibition against S aureus, P aeruginosa, E coli and C albicans. The extracts of C cajam produced wider zones of inhibition against C albicans.

• Hyperglycemic Effect: Study of the aqueous extract of C cajan leaves showed a hyperglycemic effect, suggesting a usefulness incontrolling hypoglycemia that may be due to excess of insulin or other hypoglycemic drugs.

• Hepatoprotective: (1) Study of the methanol-aqueous fraction of C cajan leaf extract showed it could prevent the chronically treated alcohol induced rat liver damage and presents a promise as a non-toxic herb for therapeutic use in alcohol-induced liver dysfunction. (2) Study in mice with carbon tetrachloride-induced liver damage showed the methanol extracts of B orellana, C cajan, G pentaphylla and C equisetifolia showed significant decrease in levels of serum markers, indicating the protection of hepatic cells in a dose-dependent manner.

Disclaimer : The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplement, it is always advisable to consult with your own health care provider.

Resources:
http://en.wikipedia.org/wiki/Pigeon_pea
http://www.stuartxchange.com/Kadios.html
http://vaniindia.org.whbus12.onlyfordemo.com/herbal/plantdir.asp

http://www.hort.purdue.edu/newcrop/duke_energy/Cajanus_cajun.html

Related articles
Enhanced by Zemanta
Categories
Health & Fitness

Cutting Carbohydrates From the Diet May Increase Longivity

[amazon_link asins=’B00590I8DC,B0063RY4JM,B0081BF3ES’ template=’ProductCarousel’ store=’finmeacur-20′ marketplace=’US’ link_id=’a1f116c7-4e63-11e7-a891-adb5b3caa04a’]

You may be able to extend your life and stay fit throughout your old age with a simple change of diet that switches on your “youth” gene.

Professor Cynthia Kenyon, whom many experts believe should win the Nobel Prize for her research into aging, has discovered that carbohydrates directly affect the genes that govern youthfulness and longevity.

By tweaking the genes of roundworms, she has been able to help them live up to six times longer than normal.
->The carbohydrates we eat directly affect two key genes that govern youthfulness and longevity
The genes that controlled aging in worms also do the same thing in rats and mice, probably monkeys, and there are signs they are active in humans, too. She found that turning down the gene that controls insulin in turn switches on another gene which acts like an elixir of life.

The Daily Mail reports:
“Discovering the … [first] gene has prompted the professor to ­dramatically alter her own diet, cutting right back on carbohydrates. That’s because carbs make your body produce more insulin (to mop up the extra blood sugar carbs ­produce) … so the vital second gene, the ‘elixir’ one, won’t get turned on.”

Source: Daily Mail October 26, 2010

Related articles
Enhanced by Zemanta
Categories
Herbs & Plants

Asteracantha longifolia Nees (Bengali Name : Kuliakhara)

[amazon_link asins=’B01AOUXCSW,B01LJ5JQY0,B01F6W2RLG,B01AQBCBCW,B01EVOV3FG,B00TGAVDYM’ template=’ProductCarousel’ store=’finmeacur-20′ marketplace=’US’ link_id=’8ca578bb-f19e-11e6-87c7-cf25133a7bb2′]

Botanical Name : Asteracantha longifolia Nees

Family: Acanthaceae
Genus: Astercantha
Species: A. longifolia
Kingdom: Plantae
Order: Lamiales
Syn. / Hygrophila spinosa T. Anders. /Asteracantha longifolia (Linn.) Nees. (Acanthaceae).
English Name : Hygrophila
Sanskrit Names : Kokilaksha, Ikshura, Ikshuraka, Chulli
Hindi Name:Talimakhana
Bengali Name : Kuliakhara

Habitat : It grows throughout India.Throughout the Philippines in stagnant streams, fresh-water swamps, and  ponds.

Description:
It is a robust, erect, annual herb. The stems are sub-quadrangular with thickened nodes; the leaves are oblanceolate, with a yellow spine in its axil; the flowers pale, purple blue, densely clustered in  axils; the fruits are oblong, glabrous capsules, 4-8 seeded.
…click to see the picture

click to see the picture….…(01)...…(1).….…(2)...…………………….

 

A smooth, widely spreading vine, with the stems trailing on mud or floating on water. Leaves are oblong-ovatem 7-14 cm long, with a pointed tip and heart- or arrow-shaped base, long petioled, the margins entire or angular, and sublobed.
The pedcuncles are erect, 2.5 to 5 cm long, with 1 or 2 flowers in the axils of the leaves. Sepals are green, oblong, about 8 mm. The corolla is narrowly bell-shaped, about 5 mm long, and purplish with the tube deeper purple inside.


Principal Constituents: The seeds contain large amount of tenacious mucilage and potassium salts.

Medicinal Uses:
The roots, leaves and seeds have been used in Indian systems of medicine as diuretics and also employed to cure jaundice, dropsy, rheumatism, anasarca and diseases of the urinogenital tract.
The plant contains abundant mucilage and potassium salts, which ultimately increases blood circulation in the body. The whole plant possesses tonic and diuretic properties. The seeds are given for gonorrhoea. The root, in decoction, is administered in dropsical cases and gravel; The leaves are also used as a diuretic after being boiled in vinegar. The ashes of the dried plants are considered

Click to see :
Kuliakhara herb Asteracantha longifolia plant for liver health and sexual enhancement :
Revista Brasileira de Farmacognosia  :
Asteracantha longifolia plant health benefit  :

Folkloric
Tops are mildly laxative.
The purplish variety used for diabetes because of assumed insulin-like principle it contains.
Juice used as emetic.
Dried latex is purgative.
Poultice of buds used for ringworm.
In Ayurveda, exgtracts of leaves are used for jaundice and nervous debility.
Juice used as emetic in opium and arsenic poisoning.
In Sri Lanka, used for liver disease, eye problems, constipation.

Studies :
• Hypoglycemic / Anti-Diabetic: (1) Study showed the boiled whole extract of I. aquatica to exert an oral hypoglycemic effect in healthy, male, Wistar rats after a glucose challenge. (2) An aqueous extract of the green leafy vegetable Ipomoea aquatica is as effective as the oral hypoglycaemic drug tolbutamide in reducing the blood sugar levels of Wistar rats.(3) Inhibitory effect of Ipomoea aquatica extracts on glucose absorption using a perfused rat intestinal preparation: Study showed a significant inhibitory effect on glucose absorption. Furthermore, results suggest the inhibition of glucose absorption is not due to the acceleration of intestinal transit. (3) Study showed the consumption of shredded, fresh, edible portion of IA for one week, effectively reduced the fasting blood sugar of Streptozotocin-induced diabetic rats.

• Antioxidant / Antiproliferative: Antioxidant and antiproliferative activities of water spinach (Ipomoea aquatica Forsk) constituents: Study showed the water extract of stems had the highest antiproliferative activity. The ethanol extract of the stems had the highest total phenolic compounds. The ethanol extract of leafves had the highest amount of flavonoids.

• Diuretic: Study on the diuretic activity of the methanol extract of Ipomoea aquatica in Swiss albino mice showed good diuretic activty. In all cases, the excretion of electrolytes and urine volue increase was higher than the standard diuretic, furosemide.

• Antioxidant: Study of a methanol extract yielded a compound ( 7-O-B-D-glucopyronosyl-dihydromquercetin-3-O-a-D-glucopyranoside) that exhibited antioxidant activity with an EC50 value of 83 and showed very strong lipid peroxidation-inhibitory activirty in a liposome model system.

• Antimicrobial: Study investigating the antimicrobial efficacy of the leaf extract of three herbs – A longifolia, I aquatica and E fluctuans – on four pathogenic bacterial strains (E coli, P aeruginosa, S aureus and M luteus). Ipomoea aquatica exerted the higher amount of antimicrobial activity against the bacterial strains, better than the two other herb extracts.

• Antiulcerogenic: Study in an aspirin-induced ulcer model in rats found Ipomoea aquatica to possess potent anti-ulcerogenic and ulcer-healing properties and can act as a potent therapeutic agent against peptic ulcer disease.

• Cytotoxicity: Study isolated a purified bioactive compound from the leaf of Ipomoea aquatica – 7-O-B-D-glucopyranosyl-dihydroquercetin-3-O-a-D-glucopyranoside (DHQG). Results showed DHQG showed cytotoxicity towards cancer cell lines tested.

• Nootropic / Memory Enhancing Potential: Study suggests that MEIA markedly improves brain Ach level. MEIA treatment may be of value in reinforcing depressed cholinergic transmission in certain age related memory disorders and to improve memory and learning in normal individuals.

Disclaimer:
The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

Resources:
http://www.la-medicca.com/raw-herbs-asteracantha-longifolia.html
http://www.stuartxchange.com/Kangkong.html

http://en.wikipedia.org/wiki/Astercantha_longifolia

Related articles
Enhanced by Zemanta
css.php