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Herbs & Plants

Nicotiana benthamiana

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Botanical Name: Nicotiana benthamiana
Family: Solanaceae
Genus: Nicotiana
Species:N. benthamiana
Kingdom:Plantae
Order: Solanales

Synonyms: Nicotiana suaveolens var. cordifolia

Common indigenous names: Tjuntiwari and Muntju. Tangungnu, Ngkwerlp-pweter, Pinapitilypa, Tjiknga, Munju, Pirnki-warnu, Turlkamula

Habitat :Nicotiana benthamiana is native to Australia.It is found amongst rocks on hills and cliffs throughout the northern regions of Australia.

Description:
Nicotiana benthamiana is an erect, sometimes sprawling, annual herbaceous plant. This short-lived herb will reach from 0.65-5 feet (0.2-1.5 m) tall. Grown in containers, the plants rarely reach over 18 inches (0.45 m) tall by about half as wide. The dark green, broadly ovate leaves will reach up to 4 inches (10 cm) wide by 5 inches (12.7 cm) long. We selected this plant to use for TMV research because it is very susceptible to all kinds of viruses. Plants are easy to grow and we always keep several different ages of plants available at all times.

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Blooming: In the greenhouse, plants flower all year round, but in nature, they normally bloom from May-September. The small, white flowers are 3/8 inch (1 cm) across by 1.5 inches (3.8 cm) long.

A vigorous plant with numerous erect leafy stems. Its alternate leaves are broadly egg-shaped, dull green and soft. Except at the top of the stems, where they are stalkless, its leaves have slender stalks. Flowers are whitish, with a long, slender tube and five blunt lobes; fruits are capsules containing many pitted seeds.

This plant is a close relative of tobacco and species of Nicotiana indigenous to Australia.The plant was used by peoples of Australia as a stimulant – it contains nicotine and other alkaloids – before the introduction of commercial tobacco (N.tabacum and N.rustica). It was first collected on the north coast of Australia by Benjamin Bynoe on a voyage of the H.M.S. Beagle in 1837.

Cultivation:
Nicotiana benthamiana need full sun to partial shade using a well-drained soil mix. In the greenhouse, we use a soil mix consisting of 2 parts peat moss to 1 part loam to 1 part coarse sand or perlite. Since we grow these plants for research, they are given water on a daily basis to keep them stress free. They are fertilized weekly with a balanced fertilizer diluted to 1/2 the strength recommended on the label. Since we have to have these plants for research, once they set seed, plants are discarded. During the winter months, we use supplemental lighting to keep the plants growing strong.

Propagation: Nicotiana benthamiana is best propagated from seed.
Medicinal Uses:
The scientists have shown that transgenic versions of a plant Nicotiana benthamiana, also known as ‘Tjuntiwari’ in the native language, may be able to produce large quantities of a protein griffithsin which can be used as an anti-HIV microbicide gel.The protein has shown capabilities of neutralizing HIV as it binds to the virus molecule in such a way that the virus could not disguise itself from the immune system of humans.

Anti-HIV microbicide gel directly targets entry of the virus and averts infection at the surfaces but at present they are being produced using biologicals like bacteria E.coli, an expensive process which is not cost-effective.

The researchers from USA and UK altered the genetic nature of the plant using a tobacco mosaic virus which produced the protein griffithsin.(Published in The Times Of India)

Disclaimer : The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplement, it is always advisable to consult with your own health care provider.

Resources:
http://en.wikipedia.org/wiki/Nicotiana_benthamiana
http://www.plantoftheweek.org/week425.shtml
http://biolinfo.org/cmkb/view.php?comname=cmkb_public&scid=412

Categories
Herbs & Plants

Tragopogon porrifolius

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Botanical Name : Tragopogon porrifolius
Family: Asteraceae
Genus: Tragopogon
Species: T. porrifolius
Kingdom: Plantae
Order: Asterales

Synonyms: Purple Goat’s Beard. Vegetable Oyster.
(French) Salsifis des prés.

Common Names :Purple or Common salsify, Oyster plant, Vegetable oyster, Jerusalem star,Goatsbeard or Simply salsify (although these last two names are also applied to other species, as well).

Habitat :Tragopogon porrifolius is   native to Mediterranean regions of Europe but introduced elsewhere, for example, into the British Isles (mainly in central and southern England), other parts of northern Europe, North America, and southern Africa and in Australia; in the United States it is now found growing wild in almost every state, including Hawaii, except in the extreme south-east.This plant is normally found near the sea and estuaries in S.E. England

Description:
Tragopogon porrifolius is a common biennial wildflower plant growing  to around 120 cm in height. As with other Tragopogon species, its stem is largely unbranched, and the leaves are somewhat grasslike. It exudes a milky juice from the stems.In the UK it flowers from June to September, but in warmer areas such as California it can be found in bloom from April. The flower head is about 5 cm across, and each is surrounded by green bracts which are longer than the petals (technically, the ligules of the ray flowers). The flowers are like that of Goatsbeard Tragopogon pratensis, but are larger and dull purple, 30-50mm across. The flowers are hermaphroditic, and pollination is by insects.

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The fruits are of the clock variety.The seeds ripen from July to September.

Cultivation:     
Succeeds in ordinary garden soils, including heavy clays. Plants do not grow well in stony soils. Prefers an open situation and a cool moist root run. Salsify is occasionally cultivated in the garden for its edible root, there are some named varieties. Grows well with mustard.

Propagation:  
Seed – sow in situ as early in the year as possible, in March if weather conditions permit. Seed sowings often fail unless the soil is kept moist until the seedlings are growing well.

Edible Uses: 
Edible Parts: Flowers;  Leaves;  Root;  Seed;  Stem.

Root – raw or cooked. The young root can be grated in salads, older roots are best cooked. The flavour is mild and sweet, and is said to resemble oysters. The roots are harvested as required from October until early spring, or can be harvested in late autumn and stored until required. Young shoots – raw or cooked. The new growth is used in spring. A sweet taste. Flowering shoots – raw or cooked. Used like asparagus. Flowers – raw. Added to salads[183]. The sprouted seeds can be added to salads or sandwiches. The root latex is used as a chewing gum.

Meditional Uses:

Antibilious;  Aperient;  Deobstruent;  Diuretic.

Salsify is a cleansing food with a beneficial effect upon the liver and gallbladder. The root is antibilious, slightly aperient, deobstruent and diuretic. It is specific in the treatment of obstructions of the gall bladder and jaundice and is also used in the treatment of arteriosclerosis and high blood pressure

Other Uses : Gum.

Disclaimer:
The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

Resources:
http://www.pfaf.org/user/plant.aspx?LatinName=Tragopogon+porrifolius
http://en.wikipedia.org/wiki/Tragopogon_porrifolius
http://www.botanical.com/botanical/mgmh/s/salsaf08.html

Categories
Herbs & Plants

Carrion Flower

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Botanical Name :Smilax herbacea
Family :Smilacaceae – Catbrier family
Genus :Smilax L. – greenbrier
Species: Smilax herbacea L. – smooth carrionflower
Kingdom :Plantae – Plants
Subkingdom: Tracheobionta – Vascular plants
Superdivision: Spermatophyta – Seed plants
Division: Magnoliophyta – Flowering plants
Class :Liliopsida – Monocotyledons
Subclass: Liliidae
Order: Liliales

Common Name :Carrion Flower

Habitat :According to official records, Smooth Carrion Flower is rare in Illinois. However, in neighboring states this vine has been found in many counties and it is regarded as more common. It is possible that some records of Smilax lasioneura (Common Carrion Flower) in Illinois are based on misidentifications and it was Smooth Carrion Flower that was observed. These two species are very similar in appearance and easily confused. Habitats of Smooth Carrion Flower include savannas, thickets, prairies, rocky upland woodlands, woodland openings, woodland borders, and fence rows. Occasional wildfires appear to be beneficial in managing populations of this species.

Description:
This climbing non-woody vine is a native perennial up to 8′ long that branches occasionally. The light green to purple stems are terete, slightly speckled, glabrous, and often glaucous. Alternate leaves up to 3½” long and 2½” across occur at intervals along each stem; they are ovate-oval to broadly ovate-lanceolate in shape, smooth along their margins, and parallel-veined. The upper surfaces of the leaves are medium green and glabrous, while their lower surfaces are pale green and hairless. There are no hairs along the raised veins on the leaf undersides. The petioles of the leaves are up to 1¾” long, light green, and hairless. At the base of most petioles, there is a pair of tendrils that can cling to adjacent vegetation or objects for support. At the base of each stem on the vine, there is an appressed to slightly spreading sheath that is usually bladeless.
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Individual umbels of flowers are produced from the axils of the middle to upper leaves of each mature vine. Each umbel is connected to the stem by a long stout peduncle about 4-10″ long. The peduncles are 4-8 times longer than the petioles of adjacent leaves; they are similar in appearance to the stems. Individual umbels are about 1½–3″ across, consisting of 20-120 flowers on slender pedicels; when fully developed, they are globoid in shape. Like other species in this genus, Smooth Carrion Flower is dioecious; some vines produce only staminate (male) flowers, while other vines produce only pistillate (female) flowers. The green to yellowish green staminate flowers are individually about ¼” across, consisting of 6 lanceolate tepals and 6 stamens with white anthers. The green to yellowish green pistillate flowers are individually about ¼” across, consisting of 6 lanceolate tepals and a pistil with 3 flattened stigmata. The tepals of both kinds of flowers are often recurved. The blooming period occurs from late spring to early summer and lasts about 3 weeks. The flowers often have a carrion-like scent, but its presence and strength varies with the local ecotype. Staminate flowers wither away after blooming, while pistillate flowers are replaced by globoid fleshy berries. Individual berries are about ¼” across and contain about 3-5 seeds; they are dark blue and glaucous at maturity. At the end of the growing season, the entire vine dies down to the ground.

Cultivation: Smooth Carrion Flower prefers full or partial sun and more or less mesic conditions. It flourishes in different kinds of soil, including those that are rocky or loamy. In a shady situation, this vine may fail to produce flowers.

Medicinal Uses:
Eating the fruit is said to be effective in treating hoarseness.  The parched and powdered leaves havebeen used as a dressing on burns. The wilted leaves have been used as a dressing on boils. The root is analgesic. A decoction has been used in the treatment of back pains, stomach complaints, lung disorders and kidney problems.

Disclaimer:
The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

 

Resources:
http://www.herbnet.com/Herb%20Uses_C.htm
http://plants.usda.gov/java/profile?symbol=SMHE
http://www.ct-botanical-society.org/galleries/smilaxherb.html
http://www.illinoiswildflowers.info/savanna/plants/sm_carrion.htm

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Therapetic treatment

Electro-Convulsive Therapy

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Definition:
Electroconvulsive therapy (ECT) is a procedure in which electric currents are passed through the brain, deliberately triggering a brief seizure. Electroconvulsive therapy seems to cause changes in brain chemistry that can immediately reverse symptoms of certain mental illnesses. It often works when other treatments are unsuccessful.

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Electroconvulsive therapy (ECT), formerly known as electroshock, is a psychiatric treatment in which seizures are electrically induced in anesthetized patients for therapeutic effect. Its mode of action is unknown. Today, ECT is most often recommended for use as a treatment for severe depression which has not responded to other treatment, and is also used in the treatment of mania and catatonia. It was first introduced in the 1938 and gained widespread use as a form of treatment in the 1940s and 1950s.

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Informed consent is a standard of modern electroconvulsive therapy. According to the Surgeon General, involuntary treatment is uncommon in the United States and is typically only used in cases of great extremity, and only when all other treatment options have been exhausted and the use of ECT is believed to be a potentially life saving treatment. However, caution must be exercised in interpreting this assertion as, in an American context, there does not appear to have been any attempt to survey at national level the usage of ECT as either an elective or involuntary procedure in almost twenty years. In one of the few jurisdictions where recent statistics on ECT usage are available, a national audit of ECT by the Scottish ECT Accreditation Network indicated that 77% of patients who received the treatment in 2008 were capable of giving informed consent

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Electroconvulsive therapy can differ in its application in three ways: electrode placement, frequency of treatments, and the electrical waveform of the stimulus. These three forms of application have significant differences in both adverse side effects and positive outcomes. After treatment, drug therapy is usually continued, and some patients receive continuation/maintenance ECT. In the United Kingdom and Ireland, drug therapy is continued during ECT.

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The treatment involves placing electrodes on the temples, on one or both sides of the patient’s head, and delivering a small electrical current across the brain, with the patient sedated or under anaesthetic. The aim is to produce a seizure lasting up to a minute, after which the brain activity should return to normal. Patients may have one or more treatment a week, and perhaps more than a dozen treatments in total.

Although ECT has been used since the 1930s, there is still no generally accepted theory to explain how it works. One of the most popular ideas is that it causes an alteration in how the brain responds to chemical signals or neurotransmitters.

Why & when it is done?
Electroconvulsive therapy (ECT) can provide rapid, significant improvements in severe symptoms of a number of mental health conditions. It may be an effective treatment in someone who is suicidal, for instance, or end an episode of severe mania.

ECT is used to treat:
*Severe depression, particularly when accompanied by detachment from reality (psychosis), a desire to commit suicide or refusal to eat.

*Treatment-resistant depression, long-term depression that doesn’t improve with medications or other treatments.

*Schizophrenia, particularly when accompanied by psychosis, a desire to commit suicide or hurt someone else, or refusal to eat.

*Severe mania, a state of intense euphoria, agitation or hyperactivity that occurs as part of bipolar disorder. Other signs of mania include impaired decision making, impulsive or risky behavior, substance abuse and psychosis.

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*Catatonia, characterized by lack of movement, fast or strange movements, lack of speech, and other symptoms. It’s associated with schizophrenia and some other psychiatric disorders. In some cases, catatonia is caused by a medical illness.

Electroconvulsive therapy is sometimes used as a last-resort treatment for:

#Treatment-resistant obsessive compulsive disorder, severe obsessive compulsive disorder that doesn’t improve with medications or other treatments

#Parkinson’s disease, epilepsy, and certain other conditions that cause movement problems or seizures

*Tourette syndrome that doesn’t improve with medications or other treatments

ECT may be a good treatment option when medications aren’t tolerated or other forms of therapy haven’t worked. In some cases ECT is used:

#During pregnancy, when medications can’t be taken because they might harm the developing fetus

#In older adults who can’t tolerate drug side effects

#In people who prefer ECT treatments over taking medications

#When ECT has been successful in the past

Risk factor:
Patients are given short-acting anaesthetics, muscle relaxants and breathe pure oxygen during the short procedure in order to minimise the risks. However, although ECT is much safer than it was, there are still side effects to the treatment. The most common are headache, stiffness, confusion and temporary memory loss on awaking from the treatment – some of these can be reduced by placing electrodes only on one side of the head. Memory loss can be permanent in a few cases, and the spasms associated with the seizure can cause fractured vertebrae and tooth damage. However, the recommended use of muscle relaxant nowadays makes the latter a very rare occurrence. Patients can also experience numbness in the fingers and toes.

The death rate from ECT used to be quoted as one for every 1,000 patients, but with smaller amounts of electric current used in modern treatments, accompanied by more safety techniques, this has been reduced to as little as four or five in 100,000 patients.

Recomendations:
A common argument against ECT is that it destroys brain cells, with experiments conducted on animals in the 1940s often cited as evidence. However, modern studies have yet to reproduce these findings in the human brain.

Some activists, however, still campaign against the widespread use of ECT in psychiatry, quoting those cases which have resulted in long-term damage or even death, whether because of the built-in chance of problems, or through errors by doctors.

Experts say that given the correct staff training, and when used for the right clinical conditions, ECT can ‘dramatically’ benefit the patient. An audit of ECT in Scotland between February 1996 and August 1999 said concerns about unacceptable side effects, effectiveness of the treatment and disproportionate use on elderly people were ‘largely without foundation’.

It said that in nearly three quarters of cases people with depressive illness showed ‘a definite improvement’ after ECT. Women were more likely to receive the treatment than men, but the auditors said this was because they were twice as likely to suffer from depression. Only 12 per cent of patients who got ECT were aged over 75. However, the Royal College of Psychiatrists has admitted that in the past the treatment has been administered by untrained, unsupervised junior doctors. However, modern guidelines have changed this and ECTAS (ECT Accreditation Services) exist to check that such treatment is being given safely and efficiently.

Guidelines on ECT from NICE (2003) recommend that it’s used only to achieve rapid and short-term improvement of severe symptoms after an adequate trial of other treatment. options has proven ineffective and/or when the condition is considered to be potentially life-threatening, in individuals with:

•Severe depressive illness
•Catatonia
•Prolonged or severe manic episode

NICE also says that ‘valid consent should be obtained in all cases where the individual has the ability to grant or refuse consent. The decision to use ECT should be made jointly by the individual and the clinician(s) responsible for treatment, on the basis of an informed discussion. This discussion should be enabled by the provision of full and appropriate information about the general risks associated with ECT and about the risks and potential benefits specific to that individual. Consent should be obtained without pressure or coercion, which may occur as a result of the circumstances and clinical setting, and the individual should be reminded of their right to withdraw consent at any point. There should be strict adherence to recognised guidelines about consent and the involvement of patient advocates and/or carers to facilitate informed discussion is strongly encouraged.’

 

Click to learn more  in detail  about  Electro-Convulsive Therapy

You may click to see:-

Keep fighting even when depression treatments don’t work
Video:Electroconvulsive therapy

DSM-IV Codes
Harold A. Sackeim
Insulin shock therapy
History of electroconvulsive therapy in the United Kingdom
Psychiatric survivors movement
Consumer/Survivor/Ex-Patient Movement
List of people who have undergone electroconvulsive therapy

 

Resources:
http://www.mayoclinic.com/health/electroconvulsive-therapy/MY00129
http://www.bbc.co.uk/health/physical_health/conditions/electro_convulsive_therapy.shtml
http://en.wikipedia.org/wiki/Electroconvulsive_therapy

http://www.minddisorders.com/Del-Fi/Electroconvulsive-therapy.html

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News on Health & Science

Protein Intake Increases Hip Fracture Prevention

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Higher levels of protein intake may lower the risk of hip fractures in seniors, according to a study published in Osteoporosis International.
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A team of researchers from the Institute for Aging Research of Hebrew SeniorLife in Boston enrolled 946 elderly participants in the Framingham Osteoporosis Study, which examined the effects of consuming higher amounts of protein.

The results of the study showed that individuals who had the lowest protein intake were 50 percent more likely to suffer from hip fractures.

While other studies have found that protein intake is associated with an increase in bone mineral density, the researchers from this study stated that a higher intake of protein also builds strong muscles in the legs, which lowers the possibility of falling and suffering a hip fracture.

Marian T. Hannan, lead author and co-director at the Musculoskeletal Research Program at the Institute for Aging Research, stated that “[the] study participants who consumed higher amounts of protein in their diet were significantly less likely to suffer a hip fracture.”

People who wish to add more protein to their daily diet can benefit from consuming fish, leaner meats, dairy products, as well as different types of beans, which are all high sources of protein, according to the University of Pittsburgh Medical Center.


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