Categories
Diagnonistic Test

Transrectal Ultrasound and Biopsy of the Prostate

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What is the test?
Your doctor is likely to recommend this test if you’ve had a rectal exam or blood tests that suggest that you might have prostate cancer. For this test, a urologist takes tissue samples from several places in your prostate, to be examined for cancer. A transrectal ultrasound helps the urologist see the prostate during the procedure.

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How do you prepare for the test?
Some doctors recommend that you have an enema before the test. Tell your doctor if you have any allergies, especially to antibiotics.

What happens when the test is performed?
In most cases, you lie on your side with your knees bent up to your chest. An ultrasound machine’s sensor-a short rod about the width around of two fingers-is covered with a condom and clear jelly and gently inserted into your rectum. You may feel some pressure similar to the sensation before a bowel movement. Once the sensor is in place, an image of your prostate appears on a video screen.

The ultrasound sensor surveys the whole prostate gland and pinpoints specific areas for biopsy. Then the doctor removes this ultrasound sensor and replaces it with a slightly smaller one. In addition to generating an ultrasound image, the smaller sensor has a small tube on its side called a needle guide. Your doctor points the needle guide at specific parts of your prostate. The guide releases a spring-loaded needle to take biopsies from different parts of the prostate. The spring-loading allows this needle to move into and out of the prostate very quickly. You are likely to feel some discomfort from each biopsy, but because the needle moves so quickly, any pain lasts only for a second at a time. Doctors usually collect multiple samples.Your doctor will probably give you antibiotics at the end of this procedure to prevent infection.

What risks are there from the test?
Many people have some blood in their urine or stool for a day or two after the biopsy. The only significant risk is the possibility of an infection in the prostate, but antibiotics can help prevent this.

Must you do anything special after the test is over?
Call your doctor if you develop a fever.

How long is it before the result of the test is known?
A pathologist will examine the biopsies under a microscope for cancer. This process usually requires several days.

For more knowledge & information you may click :-http://emedicine.medscape.com/article/457757-overview

Source:https://www.health.harvard.edu/fhg/diagnostics/transrectal-ultrasound-and-biopsy-of-the-prostate.shtml

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Categories
Diagnonistic Test

Anoscopy

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Definition:
An anoscopy is an examination of the rectum in which a small tube is inserted into the anus to screen, diagnose, and evaluate problems of the anus and anal canal.

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Anoscopy views the anus and anal canal by using an anoscope. An anoscope is a plastic, tube-shaped speculum that is a smaller version of a sigmoidscope. Before the anoscope is used, the doctor completes a digital rectal examination with a lubricated, gloved index finger. The anoscope is then lubricated and gently inserted a few inches into the rectum. This procedure enlarges the rectum to allow the doctor to view the entire anal canal with a light. If any suspicious areas are noticed, a piece of tissue can be biopsied.
What is the Purpose of the test?
Doctors use anoscopy to diagnose rectal cancer and cancer of the anus. This procedure can also help the doctor:

*:detect any lesions that could not be felt during a digital examination

*determine whether squamous cell carcinomas involving lymph nodes in or near the groin (inguinal lymph nodes) originated in the genital area or in or near the anus or rectum

*confirm the source of malignancies that have spread to the anorectal area from other parts of the body
Doctors also perform anoscopy to determine whether a patient has hemorrhoids or anal:

*growths or nodules (polyps)
*ulcer-like grooves (fissures)
*inflammation
*infection

.How do you prepare for the test?
Before the test, you might want to empty your bladder or have a bowel movement to make yourself more comfortable. The doctor may suggest using:

*a laxative,
*an enema,
*or some other preparationto clear the rectum.

What happens when the test is performed?
This test is usually done in a doctor’s office. You need to remove your underwear.After removing underwear, the patient bends forward over the examining table or lies on one side with knees drawn up to the chest. The doctor performs a digital examination to make sure no tumor or other abnormality will obstruct the passage of a slender lubricated tube (anoscope). As the doctor gently guides the anoscope a few inches into the rectum, the patient is told to bear down as though having a bowel movement, thenrelax.

CLICK & SEE THEPICTURES

By tensing and relaxing, the patient makes it easier for the doctor to insert the anoscope, and discover growths in the lining of the rectum that could not be detected during the digital examination.

Directing a light into the anoscope gives the doctor a clear view of any tears or other irregularities in the lower anus or rectum. A doctor who suspects that a patient may have cancer will remove tissue for biopsy in the course of this procedure.

Slowly withdrawing the anoscope allows the doctor to thoroughly inspect the entire anal canal. As the procedure is being performed, the doctor explains what is happening, and why the patient feels pressure.

Removing tissue samples for biopsy can pinch, but anoscopy does not usually cause pain. Patients do experience the sensation of needing to have a bowel movement.

Risk Factors:
There are no significant risks from anoscopy. Sometimes, especially if you have hemorrhoids, you may have a small amount of bleeding after the anoscope is pulled out.

Must you do anything special after the test is over?
You can return to your normal activities immediately.
How long is it before the result of the test is known?
Your doctor can tell you about your anoscopy exam right away.

RESULTS:

Normal Results

A normal anoscopy reveals NO evidence of:

*tumor
*tissue irregularities
*polyps
*fissures
*hemorrhoids
*inflammation
*infectionor other abnormalities. The size, color, and shape of the anal canal look like they should.

Abnormal Results

Abnormal results of anoscopy can indicate the PRESENCE of:

*cancer
*abscesses
*polyps
*inflammation
*infection
*fissures
*hemorrhoids

Resources:
https://www.health.harvard.edu/fhg/diagnostics/anoscopy.shtml
http://www.answers.com/topic/anoscopy-1

Categories
News on Health & Science

Slash Your Prostate Cancer Risk — With Sunlight!

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Men with prostate cancer are as much as seven times less likely to die if they have high levels of the “sunshine vitamin” — vitamin D — according to a new study.
click & see
The research looked at 160 patients with prostate cancer who were classified as having either low, medium, or high blood levels of vitamin D. Over the course of the multi-year study, 52 of the patients died of prostate cancer. Low vitamin D levels were found to significantly affect chances of survival.

The study’s authors theorized that since vitamin D has a similar structure to androgen, it might amplify the therapeutic effects of lowering androgen levels and improve the survival chances of men with prostate cancer.

Sources: British Journal of Cancer 2009; 100: 450-454

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Categories
News on Health & Science

New Cure for Prostate Cancer

Scientists have developed a potential new treatment for prostate cancer, offering hope to thousands of patients.

It is a monoclonal antibody to a unique tumor marker for prostate cancer, said Pei Xiang Xing, associate professor who heads Burnet Institute‘s Cancer Immunotherapy Lab, Melbourne and led the research team.

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The monoclonal antibody is directed at cancer-producing cells carrying the specific molecule known as PIM-1, which is responsible for cell survival, proliferation and differentiation.

Over-expression of PIM-1 plays a critical role in the development, progression and metastasis of prostate cancer and other cancers such as leukemia. The monoclonal antibody significantly inhibited cancer cell growth when used in laboratory models of prostate cancer.

Xing’s group demonstrated that the monoclonal antibody binds to PIM-1 present in cancer cells and creates a chain of events leading to the death of the cells. In particular, the therapeutic effect was improved by combination of the antibody with other drugs currently used to treat prostate cancer.

Prostate cancer is one of the most frequently diagnosed invasive cancers and the third leading cause of death in men worldwide, which claims more than 3,000 lives every year, equal to the number of women who die from breast cancer.

A new strategy to treat prostate cancer is urgently needed as there is no efficient method to treat advanced prostate cancer, said a Burnet release.

Burnet Institute’s director Brendan Crabb described it as “an exciting step in the development of new treatments for patients with prostate cancer with very promising laboratory-test results”.

Sources: The Times Of India

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Categories
Ailmemts & Remedies

Prostatitis

Prostate with seminal vesicles and seminal duc...
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Definition:
Prostatitis is inflammation or infection of the prostate gland — an organ about the size and shape of a walnut, located just below the bladder in males. The prostate gland produces semen, the fluid that helps nourish and transport sperm. Prostatitis can cause a variety of symptoms, including a frequent and urgent need to urinate and pain or burning when urinating — often accompanied by pelvic, groin or low back pain.

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Prostatitis has been classified by the National Institutes of Health (NIH) into four categories.

Category I
Main article: Acute prostatitis
Acute prostatitis is a bacterial infection of the prostate gland that requires urgent medical treatment.

Category II
Main article: Chronic bacterial prostatitis
Chronic bacterial prostatitis is a relatively rare condition that usually presents as intermittent urinary tract infections.

Category III
Main article: Chronic prostatitis/chronic pelvic pain syndrome
Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS), accounting for 90%-95% of prostatitis diagnoses, is also known as chronic nonbacterial prostatitis. The annual prevalence in the population of chronic pelvic pain syndrome is 0.5%. Men in this category have no known infection, but do have extensive pelvic pain lasting more than 3 months. There are no standard diagnostic tests; diagnosis is by exclusion of other disease entities. Multimodal therapy is the most successful treatment option, and includes ?-blockers, phytotherapy, and protocols aimed at quieting the pelvic nerves through myofascial trigger point release with psychological re-training for anxiety control. Antibiotics are not recommended.

Category IV
Main article: Asymptomatic inflammatory prostatitis
Asymptomatic inflammatory prostatitis patients have no history of genitourinary pain complaints, but leukocytosis is noted, usually during evaluation for other conditions. Between 6-19% of men have pus cells in their semen but no symptoms.

Pain relievers and several weeks of treatment with antibiotic are typically needed for category 1 and 2 prostatitis, which are bacterial infections. A variety of treatments as well as self-care measures also can provide relief. Treatment for category 3 prostatitis (nonbacterial) is less clear and mainly involves relieving symptoms. Category 4 prostatitis is usually found during examination for another reason and often doesn’t require treatment.

Symptoms
The signs and symptoms vary depending on the various types of prostatitis.

Acute bacterial prostatitis: Category 1
Signs and symptoms of this form of prostatitis usually come on suddenly and may include:

*Fever and chills

*Flu-like symptoms

*Pain in the prostate gland, lower back or groin

*Urinary problems, including increased urinary urgency and frequency, difficulty or pain when urinating, inability to completely empty the bladder, and blood-tinged urine

*Painful ejaculation

*Acute prostatitis can be a serious condition and requires immediate medical treatment. See your doctor right away if you develop any of these signs and symptoms.

Chronic bacterial prostatitis: Category 2
The signs and symptoms of this type of prostatitis develop more slowly and usually aren’t as severe as those of acute prostatitis. In addition, times when symptoms are better tend to alternate with times when symptoms are worse. Signs and symptoms of chronic bacterial prostatitis include:

*A frequent and urgent need to urinate

*Pain or a burning sensation when urinating (dysuria)

*Pain in the pelvic area

*Excessive urination during the night (nocturia)

*Pain in the lower back and genital area

*Difficulty starting to urinate, or diminished urine flow

*Occasional blood in semen or in urine (hematuria)

*Painful ejaculation

*A slight fever

*Recurring bladder infections

Chronic nonbacterial prostatitis: Category 3
The signs and symptoms of nonbacterial prostatitis are similar to those of chronic bacterial prostatitis, although you probably won’t have a fever. The only way to determine whether prostatitis symptoms are caused by bacterial infection or are nonbacterial is through lab tests to find out whether bacteria is present in the urine or prostate gland fluid.

Other conditions
Prostatitis can be difficult to diagnose, in part because its signs and symptoms often resemble those of other conditions, such as bladder infections, bladder cancer or prostate enlargement due to benign or cancerous growth of the prostate.

Causes:-
Acute bacterial prostatitis: Category 1
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Bacteria normally found in your large intestine typically cause acute prostatitis. Most commonly, acute prostatitis originates in the prostate, but occasionally the infection can spread from a bladder or urethral infection.

Chronic bacterial prostatitis: Category 2..…...CLICK & SEE
It’s not entirely clear what causes a chronic bacterial infection. Sometimes it develops after an episode of acute prostatitis when bacteria remain in the prostate. Catheter tubes used to drain the urinary bladder, injury to the urinary system (such as from bike riding or horseback riding ) or infections in other parts of the body can be the source of the bacteria.

Chronic nonbacterial prostatitis: Category 3…..…CLICK & SEE
The cause or causes of this condition are not well-defined. Some theories regarding the causes are as follows:

* Other infectious agents. Some experts believe nonbacterial prostatitis may be caused by an infectious agent or agents that do not show up in standard laboratory tests.

*Heavy lifting. Lifting heavy objects when your bladder is full may cause urine to back up into your prostate causing inflammation.

*Interstitial cystitis. This condition that’s more frequently diagnosed as a cause of chronic pelvic pain in women is being more frequently recognized in men.

*Physical activity. Although regular exercise, especially jogging or biking, is great for the rest of your body, it may irritate your prostate gland.

*Pelvic muscle spasm. Urinating in an uncoordinated fashion with the sphincter muscle not relaxed may lead to high pressure in the prostate and the development of inflammation and prostatitis symptoms.

*Structural abnormalities of the urinary tract. Narrowings (strictures) of your urethra may cause increased pressure during urination and result in inflammation and symptoms.
Prostatitis is not contagious and is not a sexually transmitted disease.

You may click to learn more about the causes of Prostatitis….(1).……(2).……(3)…….(4)

Risk factors:-

Risk factors for prostatitis include bladder outlet obstruction (e.g., stone, tumor, BPH), diabetes mellitus, a suppressed immune system, and urethral catheterization (i.e., small tube inserted into the bladder through the urethra to drain urine). Some sexually transmitted diseases (STDs; e.g., nongonnococcal urethritis, gonorrhea) increase the risk for developing bacterial prostatatis. Unprotected anal and vaginal intercourse can allow bacteria to enter the urethra and travel to the prostate.
Unlike other prostate problems, you’re more likely to develop prostatitis when you’re younger, even before age 40. You may also be at increased risk if you:

*Recently had a bladder infection or an infection of your urethra

*Recently had a urinary catheter inserted during a medical procedure

*Do not empty your bladder frequently enough and you perform vigorous activities with a full bladder

*Jog or bicycle on a regular basis or ride horses

*Men with HIV also are at increased risk of bacterial prostatitis. It’s not clear why.

Complications:-
There’s no evidence that having acute or chronic prostatitis increases your risk of prostate cancer, but it may increase the level of prostate-specific antigen (PSA) in your bloodstream. PSA is a substance naturally produced in your prostate gland, and high levels in your blood may sometimes — but not always — be a sign of prostate cancer. For that reason, if you have an elevated PSA level and also have acute prostatitis, you should be rechecked after you’ve been treated with antibiotics and all prostate inflammation has resolved.

Because prostatitis interferes with the transport of sperm cells and may interfere with normal ejaculation, it can sometimes affect fertility. In addition, untreated acute prostatitis can lead to an inability to urinate, and in severe cases may result in bacteria in your bloodstream (bacteremia).

Diagnosis:-

Diagnosing prostatitis involves ruling out any other conditions that may be causing your signs and symptoms and then determining what kind of prostatitis you have.

Your doctor will likely begin by taking a medical history and performing a physical exam. You may be asked to complete a questionnaire about your symptoms. The physical exam may include checking your abdomen and pelvic area for tenderness and a digital rectal exam of your prostate.

Digital rectal exam
During a digital rectal exam, your doctor manually examines your prostate gland by gently inserting a lubricated, gloved finger into your rectum. Because the prostate gland is in front of the rectum, your doctor can feel the back surface of the gland this way. If it seems enlarged and tender to the touch, you may have prostatitis.

Urine and semen test
Your doctor may want to evaluate samples of your urine and semen for bacteria and white blood cells — key cells in your immune system’s response — to help establish a diagnosis of prostatitis.

Modern Treatments:-
The main treatment for bacterial prostatitis (category 1 and 2) is antibiotics to cure the infection. If you have acute prostatitis, you may need to be hospitalized for a few days to receive antibiotics intravenously. Some of these treatments may also be tried for chronic nonbacterial prostatitis. However, there’s no strong evidence that antibiotic therapy is useful for nonbacterial or category 3 prostatitis.

Medications
Antibiotics. Antibiotics are usually the first choice of treatment for category 1 and 2 prostatitis. Your doctor will likely begin right away with an antibiotic that fights a broad spectrum of bacteria. He or she will also proceed with testing to determine the exact bacteria causing your infection. Once the exact bacterium is identified, your doctor can prescribe a specific antibiotic that is more likely to kill the particular bacteria present.

*How long you take antibiotics depends on how well you respond to the drug. If you have category 1 prostatitis, you may need medication for a few weeks. Category 2 prostatitis is more resistant to antibiotics and takes longer to treat. You may need to continue taking medication for as long as six to 12 weeks. In some cases the infection may never be eliminated, and you could have a relapse as soon as the drug is withdrawn. If this happens, you may need to take a low-dose antibiotic indefinitely.

*Some doctors may prescribe an antibiotic for category 3 prostatitis to see if symptoms improve. For unknown reasons, some men with this condition seem to benefit from a continuous low dose of an antibiotic.
Alpha blockers. If you’re having difficulty urinating, your doctor may prescribe an alpha blocker — an oral medication that helps relax the bladder neck and the muscle fibers where your prostate joins your bladder. This may help you urinate more easily and empty your bladder more completely.

Pain relievers. Sometimes an over-the-counter pain reliever, such as aspirin or ibuprofen (Motrin, Advil, others), can make you more comfortable. Keep in mind, however, that taking too much of any of these medications can cause serious side effects including abdominal pain, intestinal bleeding or ulcers.

Muscle relaxants. Spasms of the pelvic muscles can accompany prostatitis. A combination of a muscle relaxant medication and other medications used to treat prostatitis may be helpful.

Physical therapy
Special exercises and relaxation techniques can improve symptoms of prostatitis in some men, perhaps because tight or irritated muscles can contribute to the condition. Common techniques include:

Exercise. Stretching and relaxing the lower pelvic muscles — sometimes with the addition of heat to make the muscles more limber — may help relieve your symptoms. A physical therapist can show you which exercises will benefit you the most and how to perform them. You can then do the exercises yourself at home.
Biofeedback. This technique teaches you how to control certain body responses, including relaxing your muscles. During a biofeedback session, a trained therapist applies electrodes and other sensors to various parts of your body. The electrodes are attached to a monitor that displays your heart rate, blood pressure and degree of muscle tension. You’ll see changes on the monitor and learn to control these changes on your own.
Sitz baths. Named from the German word “sitzen,” which means “to sit,” this type of bath simply involves soaking the lower half of your body in a tub of warm water. Warm baths can relieve pain and relax the lower abdominal muscles. Few treatments are easier or as relaxing.
Prostate massage. Some men have found that having their prostate massaged helps relieve congestion by unplugging the small ducts blocked by inflammation. The massage is performed using a gloved finger, similar to what is done during a digital rectal exam. This procedure is used less commonly today than it once was.
Surgical procedures
Surgical removal of the infected part of the prostate is an option in a few severe cases when other treatments don’t work. The chances of responding to a major surgical procedure for any type of prostatitis are quite low. For this reason most doctors are very hesitant to perform surgery for these conditions and generally discourage surgery even as a last resort.

Other treatments:-
Finasteride (Proscar), a drug that lowers hormone levels in the prostate, and microwave thermotherapy (heat therapy) have been used successfully in a few men with prostatitis, but there’s little long-term experience with these treatments.

Lifestyle and home remedies:-
Because traditional treatments aren’t always effective for prostatitis, many men experiment with various lifestyle changes to control their symptoms. Although no scientific evidence proves these practices are beneficial, you may want to try one or more of the following suggestions:

*Drink plenty of water.

*Limit or avoid alcohol, caffeine and spicy foods.

*Urinate at regular intervals.

*Have regular sexual activity.

*If you’re a cyclist, use a “split” bicycle seat, which reduces the pressure on your prostate.

Men with category 3 prostatitis can learn to live with the disease by limiting the things that make their symptoms worse and emphasizing the things that make them feel better.

Alternative medicine:-
Although how they work is poorly understood, some natural remedies — including saw palmetto preparations, zinc supplements and quercetin — have helped some men manage the symptoms of prostatitis.

Herbal Madication:-
THE HERBS listed below can help you overcome benign enlargement of the prostate – chronic or acute – with symptoms that include pain, frequent urination with or without a burning sensation, blood or pus in the urine, lower back pain, impotence, kidney damage, stubborn or recurring bladder infections

African pygeum, saw palmetto berries, dandelion root, slippery elm bark, marshmallow root, cat’s claw concentrate, san qi, coral calcium with trace minerals.

You may click for Homeopathic medication for Prostatitis………(1)…..(2)...(3)...(4)

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Resources:
http://www.mayoclinic.com/health/prostatitis/DS00341
http://en.wikipedia.org/wiki/Prostatitis
http://www.urologychannel.com/prostate/prostatitis/riskfactors.shtml
http://www.herbnews.org/prostatitisdone.htm

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