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News on Health & Science

Stress a Trigger for Skin Disease

Researchers from University of Medicine Berlin and McMaster University in Canada have found that stress may activate immune cells in the skin, leading to inflammatory skin disease.

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This cross talk between stress perception, which involves the brain, and the skin is mediated through the “brain-skin connection”.

The immune cells in skin can over-react, resulting in inflammatory skin diseases like atopic dermatitis and psoriasis.

Study leader Petra Arck hypothesized that stress could exacerbate skin disease by increasing the number of immune cells in the skin.

The researcher said that the team exposed mice to sound stress, and found that the stress challenge resulted in higher numbers of mature white blood cells in the skin.

Moreover, blocking the function of two proteins that attract immune cells to the skin, LFA-1 and ICAM-1, prevented the stress-induced increase in white blood cells in the skin.

Based on their observations, the researchers came to the conclusion that stress activates immune cells, which in turn are central in initiating and perpetuating skin diseases. The study by Arck appears in the November issue of The American Journal of Pathology.

Sources: The Times Of India

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News on Health & Science

Soon, an End to Anti-Rejection Drugs

In a development that will help millions of transplant patients all over the world kick their anti-rejection drugs, researchers said they have found a procedure that will boost the acceptance of a foreign part.

The complex procedure involves mixing the patient’s infection-fighting white blood cells with cells from the donor, reports BBC News website.

One patient went eight months without immunosuppressive drugs and others were switched to low doses. The study, by Germany’s University of Schleswig-Holstein, appears in Transplant International.

Currently, transplant patients must take a cocktail of powerful drugs for life to dampen down their immune system, and prevent the new organ being rejected. But the drugs themselves can cause side effects, and may not prevent the slow rejection of the organ over time.

The new technique involves giving transplant patients an infusion of specialised cells known as a transplant acceptance-inducing cells (TAICs). The TAICs are created by isolating a type of white blood cell from the donor, and modifying them chemically in the lab.

Once modified, the cells gain the ability to kill off cells in the immune system which trigger the rejection process, and to boost the action of another type of immune cell which plays a beneficial role in guarding against rejection. The cells are then cultured alongside those from the recipient – which helps prime the immune system further – before being injected into the patient.

Sources: The Times Of India

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Featured News on Health & Science

Hay Fever: Beat the Sneeze

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Hay fever sufferers face a really bad summer. Lucy Atkins offers advice.

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This summer’s pollen forecast is one of the worst ever, meaning that about one in four of us can expect to slip into a wheezing fug any minute.

Experts say that we are surprisingly inept at managing our symptoms. Many of us do not understand our hay fever triggers and take inappropriate medications. Others throw away money on alternative “remedies” that do not work.

Simply popping a pill when symptoms get out of hand is not the best approach.

“People don’t realise you have to take the right dose at the right time in order to keep levels of the drug high in your system,” says Maureen Jenkins, allergy nurse and spokeswoman for Allergy UK.

“Otherwise it just won’t work.”

Antihistamine nasal sprays can stop your nose running, nasal steroid sprays can unbung you and sprays containing a drug called sodium cromoglicate, a “mast cell stabiliser”, can stop white blood cells from releasing histamine, which causes the sneezing and itching.

But Jenkins says that “many people have no idea how to use these sprays properly.” It is no good just stuffing the product up your nose – a good spraying technique is vital (see below). It is also important to follow dosage instructions.

The sodium cromoglicate spray, for instance, will only work if you start to use it two weeks before your allergy begins, then keep using it four times a day. Many other medications work best if you start to use them before your allergies kick in, allowing the drug to build up in your system. To do this you have to know your triggers.

Though there are many pollen allergens, birch and grass are the most common. These two are usually released in different months, but experts say that this summer, perhaps because of climate change, they are likely to overlap. According to the Royal Pharmaceutical Society, more than 5million of us could be taking inappropriate medicines because we have misdiagnosed our allergies.

Talking to your pharmacist before buying medicines is the first step to a sniffle-free summer. In addition, Allergy UK has just started an “accredited pharmacy allergy screening service” in association with the National Pharmacy Association. At these centres Allergy UK-trained pharmacists can diagnose triggers then recommend the right over-the-counter medications for your specific allergy type.

They can also refer you to a GP with details of the nearest appropriate allergy specialist. GPs are a good source of help if you are a severe sufferer. Several effective antihistamines can be obtained only on prescription and some people may be suitable for a newly developed kind of immunotherapy, where you either dissolve tablets under the tongue or have regular injections.

Those who want to avoid medication may turn to anything from fish oils to Reishi mushrooms as miracle hay fever cures. But there is no clinical evidence that nutritional supplements or dietary changes work on hay fever symptoms (although the herb butterbur has shown promise in clinical trials).

Acupuncture has had mixed success in trials. Daniel Maxwell of the British Acupuncture Council, says: “It’s great for hay fever because of the significant effect it has on modulating the immune system.”

Homeopathic treatments have also shown some promising clinical results, though more trials are needed. In other words, although you can’t avoid this year’s pollen onslaught, you may be more empowered than you think to defend yourself against it.

Click for natural and home remedy for Hay Fever:->.…………………...(1)…….(2).…….(3)………(4)

Sources:Telegraph.co.uk

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Ailmemts & Remedies

Abcess

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Definition
An abscess is an enclosed collection of liquefied tissue, known as pus, somewhere in the body. It is the result of the body’s defensive reaction to foreign material.

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An abscess (Latin: abscessus) is a collection of pus (dead neutrophils) that has accumulated in a cavity formed by the tissue on the basis of an infectious process (usually caused by bacteria or parasites) or other foreign materials (e.g. splinters, bullet wounds, or injecting needles). It is a defensive reaction of the tissue to prevent the spread of infectious materials to other parts of the body.

The organisms or foreign materials kill the local cells, resulting in the release of toxins. The toxins trigger an inflammatory response, which draws large numbers of white blood cells to the area and increases the regional blood flow.

The final structure of the abscess is an abscess wall, or capsule, that is formed by the adjacent healthy cells in an attempt to keep the pus from infecting neighboring structures. However, such encapsulation tends to prevent immune cells from attacking bacteria in the pus, or from reaching the causative organism or foreign object.

Abscesses must be differentiated from empyemas, which are accumulations of pus in a preexisting rather than a newly formed anatomical cavity.

Description
There are two types of abscesses, septic and sterile. Most abscesses are septic, which means that they are the result of an infection. Septic abscesses can occur anywhere in the body. Only a germ and the body’s immune response are required. In response to the invading germ, white blood cells gather at the infected site and begin producing chemicals called enzymes that attack the germ by digesting it. These enzymes act like acid, killing the germs and breaking them down into small pieces that can be picked up by the circulation and eliminated from the body. Unfortunately, these chemicals also digest body tissues. In most cases, the germ produces similar chemicals. The result is a thick, yellow liquid—pus—containing digested germs, digested tissue, white blood cells, and enzymes.

An abscess is the last stage of a tissue infection that begins with a process called inflammation. Initially, as the invading germ activates the body’s immune system, several events occur:

*Blood flow to the area increases.
*The temperature of the area increases due to the increased blood supply.
*The area swells due to the accumulation of water, blood, and other liquids.
*It turns red.
*It hurts, because of the irritation from the swelling and the chemical activity.

These four signs—heat, swelling, redness, and pain— characterize inflammation.

As the process progresses, the tissue begins to turn to liquid, and an abscess forms. It is the nature of an abscess to spread as the chemical digestion liquefies more and more tissue. Furthermore, the spreading follows the path of least resistance—the tissues most easily digested. A good example is an abscess just beneath the skin. It most easily continues along beneath the skin rather than working its way through the skin where it could drain its toxic contents. The contents of the abscess also leak into the general circulation and produce symptoms just like any other infection. These include chills, fever, aching, and general discomfort.

Sterile abscesses are sometimes a milder form of the same process caused not by germs but by non-living irritants such as drugs. If an injected drug like penicillin is not absorbed, it stays where it was injected and may cause enough irritation to generate a sterile abscess— sterile because there is no infection involved. Sterile abscesses are quite likely to turn into hard, solid lumps as they scar, rather than remaining pockets of pus.

Manifestations
The cardinal symptoms and signs of any kind of inflammatory process are redness, heat, swelling, pain and loss of function. Abscesses may occur in any kind of solid tissue but most frequently on skin surface (where they may be superficial pustules (boils) or deep skin abscesses), in the lungs, brain, teeth, kidneys and tonsils. Major complications are spreading of the abscess material to adjacent or remote tissues and extensive regional tissue death (gangrene). Abscesses in most parts of the body rarely heal themselves, so prompt medical attention is indicated at the first suspicion of an abscess.


Causes and symptoms

Many different agents cause abscesses. The most common are the pus-forming (pyogenic) bacteria like Staphylococcus aureus, which is nearly always the cause of abscesses under the skin. Abscesses near the large bowel, particularly around the anus, may be caused by any of the numerous bacteria found within the large bowel. Brain abscesses and liver abscesses can be caused by any organism that can travel there through the circulation. Bacteria, amoeba, and certain fungi can travel in this fashion. Abscesses in other parts of the body are caused by organisms that normally inhabit nearby structures or that infect them. Some common causes of specific abscesses are:

*skin abscesses by normal skin flora….CLICK & SEE
*dental and throat abscesses by mouth flora....CLICK & SEE
*lung abscesses by normal airway flora, pneumonia germs, or tuberculosis ...CLICK & SEE
*abdominal and anal abscesses by normal bowel flora…..…..CLICK & SEE


Specific types of abscesses

Listed below are some of the more common and important abscesses.

*Carbuncles and other boils. Skin oil glands (sebaceous glands) on the back or the back of the neck are the ones usually infected. The most common germ involved is Staphylococcus aureus. Acne is a similar condition of sebaceous glands on the face and back.
*Pilonidal abscess. Many people have as a birth defect a tiny opening in the skin just above the anus. Fecal bacteria can enter this opening, causing an infection and subsequent abscess.

*Retropharyngeal, parapharyngeal, peritonsillar abscess. As a result of throat infections like strep throat and tonsillitis, bacteria can invade the deeper tissues of the throat and cause an abscess. These abscesses can compromise swallowing and even breathing.

*Lung abscess. During or after pneumonia, whether it’s due to bacteria [common pneumonia], tuberculosis, fungi, parasites, or other germs, abscesses can develop as a complication.

*Liver abscess. Bacteria or amoeba from the intestines can spread through the blood to the liver and cause abscesses.

*Psoas abscess. Deep in the back of the abdomen on either side of the lumbar spine lie the psoas muscles. They flex the hips. An abscess can develop in one of these muscles, usually when it spreads from the appendix, the large bowel, or the fallopian tubes.
Tooth abscess
A tooth abscess or root abscess is pus enclosed in the tissues of the jaw bone at the tip of an infected tooth. Usually the abscess originates from a bacterial infection that has accumulated in the soft pulp of the tooth. This is usually, but not always, associated with a dull, throbbing, excruciating ache.

A tooth abscess typically originates from dead pulp tissue, usually caused by untreated tooth decay, cracked teeth or extensive periodontal disease. A failed root canal treatment may also create a similar abscess.

There are two types of denta
Diagnosis:
The common findings of inflammation—heat, redness, swelling, and pain—easily identify superficial abscesses. Abscesses in other places may produce only generalized symptoms such as fever and discomfort. If the patient’s symptoms and physical examination do not help, a physician may have to resort to a battery of tests to locate the site of an abscess, but usually something in the initial evaluation directs the search. Recent or chronic disease in an organ suggests it may be the site of an abscess. Dysfunction of an organ or system—for instance, seizures or altered bowel function—may provide the clue. Pain and tenderness on physical examination are common findings. Sometimes a deep abscess will eat a small channel (sinus) to the surface and begin leaking pus. A sterile abscess may cause only a painful lump deep in the buttock where a shot was given.

Treatment

Since skin is very resistant to the spread of infection, it acts as a barrier, often keeping the toxic chemicals of an abscess from escaping the body on their own. Thus, the pus must be drained from the abscess by a physician. The surgeon determines when the abscess is ready for drainage and opens a path to the outside, allowing the pus to escape. Ordinarily, the body handles the remaining infection, sometimes with the help of antibiotics or other drugs. The surgeon may leave a drain (a piece of cloth or rubber) in the abscess cavity to prevent it from closing before all the pus has drained out.

Alternative treatment

If an abscess is directly beneath the skin, it will be slowly working its way through the skin as it is more rapidly working its way elsewhere. Since chemicals work faster at higher temperatures, applications of hot compresses to the skin over the abscess will hasten the digestion of the skin and eventually result in its breaking down, releasing the pus spontaneously. This treatment is best reserved for smaller abscesses in relatively less dangerous areas of the body—limbs, trunk, back of the neck. It is also useful for all superficial abscesses in their very early stages. It will “ripen” them.

Contrast hydrotherapy, alternating hot and cold compresses, can also help assist the body in resorption of the abscess. There are two homeopathic remedies that work to rebalance the body in relation to abscess formation, Silica and Hepar sulphuris. In cases of septic abscesses, bentonite clay packs (bentonite clay and a small amount of Hydrastis powder) can be used to draw the infection from the area.

Prognosis
Once the abscess is properly drained, the prognosis is excellent for the condition itself. The reason for the abscess (other diseases the patient has) will determine the overall outcome. If, on the other hand, the abscess ruptures into neighboring areas or permits the infectious agent to spill into the bloodstream, serious or fatal consequences are likely. Abscesses in and around the nasal sinuses, face, ears, and scalp may work their way into the brain. Abscesses within an abdominal organ such as the liver may rupture into the abdominal cavity. In either case, the result is life threatening. Blood poisoning is a term commonly used to describe an infection that has spilled into the blood stream and spread throughout the body from a localized origin. Blood poisoning, known to physicians as septicemia, is also life threatening.

Of special note, abscesses in the hand are more serious than they might appear. Due to the intricate structure and the overriding importance of the hand, any hand infection must be treated promptly and competently.

Prevention

Infections that are treated early with heat (if superficial) or antibiotics will often resolve without the formation of an abscess. It is even better to avoid infections altogether by taking prompt care of open injuries, particularly puncture wounds. Bites are the most dangerous of all, even more so because they often occur on the hand.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Resources:http://www.healthline.com/galecontent/abscess-1
http://en.wikipedia.org/wiki/Tooth_abscess

 

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Herbal Care

Broccoli Boosts Aging Immune Systems

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A chemical in broccoli and other cruciferous vegetables may help to restore your immune system as you age. UCLA researchers found that the chemical, sulforaphane, switches on a set of antioxidant genes and enzymes in specific immune cells, which fight the damaging effects of free radicals.

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Free radicals are a supercharged form of oxygen that can cause oxidative tissue damage — for example, they can trigger the inflammation process that causes clogged arteries. Oxidative damage is thought to be one of the major causes of aging.

According to researchers, treating older mice with sulforaphane increased their immune response to the level of younger mice.

The ability of sulforaphane to reinvigorate the immune system abilities of aged tissues could play an important role in reversing much of the negative impact of free radicals.
Sources:
Science Daily March 10, 2008
The Journal of Allergy and Clinical Immunology March 6, 2008

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