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News on Health & Science

Reduced Salt Intake Lowers Blood Pressure

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Using less amount of salt in diet can lead to slight reduction in blood pressure in the medium term, a new study has claimed. However,  whether in the long term this can also reduce the risk of late complications in people with sustained high blood pressure, otherwise known as essential hypertension, and whether in the long term their anti-hypertensive medication can be reduced remains unresolved, the study by the Institute for Quality and Efficiency in Health Care (IQWiG) concluded.

The study has been published in the form of a rapid report on 20 July 2009. This rapid report is part of a package commissioned by the Federal Joint Committee (G-BA), in which the benefit of various non-drug treatment strategies for high blood pressure are to be assessed. Stress management and more physical activity are also included, as well as giving up smoking and cutting down alcohol consumption.

This rapid report was prepared on the basis of secondary literature. In principle, this can be done if current, high quality systematic reviews are already available on a given topic. This was the case with reducing salt intake in hypertension, as IQWiG’s preliminary search revealed.

To reach the conclusion, IQWiG searched for systematic reviews that compared the following patients with hypertension: an intervention group, which was to follow a low-salt diet over a long period, versus a control group, which either did not have this target or whose salt reduction was not so great as in the intervention group.

The minimum duration of the studies had to be 4 weeks. In order not to overlook any current and potentially relevant studies, IQWiG also conducted an update search of recently published primary studies.

IQWiG was able to include in its assessment 7 reviews, in which the results of between 520 and 3391 participants from a total of 62 randomized controlled trials were analysed together.

IQWiG found that no conclusions on late complications could be drawn from the available data. The reason for this is that none of the studies had the primary goal of investigating the effects of a low-salt diet on cardiovascular disease or all-cause mortality.

However, the investigations consistently show that a reduction in salt intake can assist in lowering blood pressure: over a period of up to one year, there was a mean drop of 3.6 to 8 mmHg in systolic values and a mean drop of approximately 2 to 3 mmHg in diastolic values. This applied primarily to patients who did not take any additional anti-hypertensive drugs. The sustainability of this effect, however, remains unclear.

You may click to see:->Salt and its other adverse effects on the heart

Source: The Times Of India

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News on Health & Science

Exercise Gives More Health Benefits to Women

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A long-term study of over 8,700 middle-aged men and women has shown that women experience greater health benefits than men as a result    of exercise.
The analysis of this large Atherosclerosis Risk in Communities (ARIC) study was carried out by Keri Monda and colleagues at North Carolina University (NCU).

They found that over a 12-year period, all individuals who increased their exercise by about 180 metabolic units per week (equivalent to an additional hour of mild or 30 minutes of moderate activity per week) displayed decreased levels of triglycerides and increased levels of the “good” HDL cholesterol.

However, statistically significant decreases in the “bad” LDL cholesterol were only observed in women, with particularly strong effects in menopausal women and African-American women. And total cholesterol levels were only significantly decreased in African-American women, said an NCU release.

The authors speculate that these differences may arise from hormonal differences between the sexes, especially considering the extra effects seen post-menopause. The racial differences observed may stem from genetic variations that require further exploration.

Source: These findings appear in the August issue of Journal of Lipid Research.

 

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News on Health & Science

Healthy Secret of Red Wine Uncorked

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Resveratrol in red wine is known for controlling inflammation and promoting health. However, how the ingredient works was not known to  scientists – up till now.

In the FASEB Journal, scientists from Scotland and Singapore have unravelled how resveratrol works as an effective therapy for life-threatening inflammation.

The study, not only explains resveratrol’s one-two punch on inflammation, but also shows how it-or a derivative-can be used to treat potentially deadly inflammatory disease, such as appendicitis, peritonitis, and systemic sepsis.

“Strong acute inflammatory diseases such as sepsis are very difficult to treat and many die every day due to lack of treatment,” said Alirio Melendez, senior lecturer on the faculty of medicine at Glasgow Biomedical Research Centre in Scotland and one of the researchers involved in the work.

“Moreover, many survivors of sepsis develop a very low quality of life due to the damage that inflammation causes to several internal organs. The ultimate goal of our study was to identify a potential novel therapy to help in the treatment of strong acute inflammatory diseases,” the expert added.

To reach the conclusion, researchers administered an inflammatory agent to two groups of mice. One group was pretreated with resveratrol and the other group was not. The mice that were not pre-treated with resveratrol experienced a strong inflammatory response, simulating disease in humans, while the group pretreated with resveratrol was protected from the inflammation.

The scientists then examined the tissues of the mice to determine exactly how resveratrol was able to protect the mice from inflammation. They found that resveratrol used a one-two punch to stop inflammation in the mice by preventing the body from creating two different molecules known to trigger inflammation, sphingosine kinase and phospholipase D.

This finding suggests that resveratrol may be harnessed as a treatment for inflammatory diseases and may also lead to entirely new resveratrol-based drugs that are even more effective.

“The therapeutic potential of red wine has been bottled up for thousands of years,” said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal, “and now that scientists have uncorked its secrets, they find that studies of how resveratrol works can lead to new treatments for life-threatening inflammation.”

Source: The Times Of India

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Herbs & Plants

Curare

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Botanical Name: Chondrodendron tomentosum
Family:Menispermaceae
Genus: Chondrodendron
Species: Tomentosum
Parts Used: Leaf, Root

Synonyms: Pereira Brava. Cissampelos Pareira. Velvet Leaf. Ice Vine.
Parts Used: Dried root, bark, bruised leaves.

Common Names: Curare, Grieswurzel, Pareira Brava, Pareira, Vigne Sauvage,  pareira, uva-da-serra, uva-do-mato, ampihuasca blanca, antinupa, antinoopa, comida de venados, curari, ourari, woorari, worali, velvet leaf

Habitat: Curare is native to   West Indies, Spanish Main Brazil, Peru.  It grows in  Amazon Basin of South America.(In El Salvador and other parts of Central America)

Description:
This deciduous plant will flower in a container just prior to leafing out. The flowers are attractive red “spikes”. Zone 9+ The bright red seeds contain a number of poisonous alkaloids that have a curare-like action.

CLICK TO SEE THE PICTURES

Curare grows as a large liana, or vine, found in the canopy of the South American rainforest. The vine may get as thick as 4 inches in diameter at its base. It has large alternate, heart-shaped leaves which may be 4-8 inches long and almost as wide, with a 2-6 inches long petiole. The leaves are smooth on top with a hairy white bottom, and deeply indented veins radiating from the leaf base. Clusters of small (1/16-1/8 inches), greenish-white flowers are made up of separate male and female flowers. The fleshy fruits are oval, narrow at the base, and approximately 1-2 mm long.

Edible Uses:

The fruit of this vine is edible with a bitter-sweet taste.
Some Indians of South America crush and cook the roots and stems, and add other plants and venomous animals, mixing it until it becomes a light syrup. They call this mixture “ampi”, or “curaré”, which they use on the tip of their arrows and darts to hunt wild game. Crude curare is a dark brown or black mass with a sticky to hard consistency and an aromatic, tarry odor. The name comes from Indian word meaning “poison.”

Curare, in large doses, paralyses the motor nerve-endings in striped muscle, and death occurs from respiratory failure. Curare is very bitter, and is actually a common name for various dart poisons originating from South America.

The young flowers and new growth are added to soups and other food preparations as a soporific vegetables.

Curare has differing effects depending upon dosage, whether it is injected into muscle tissue, or ingested. Curare is used internally in tribal medicine for edema, fever, kidney stones and testicular inflammation. It is also known to relax muscles into a state of inactivity.

Under appropriate medical care and attention, curare is also used to relieve spastic paralysis, to treat some mental disorders, and to induce muscle relaxation for setting fractures. Curare is now used extensively in modern medicine. It is only toxic if it enters the bloodstream. Curare is not for sale to the general public.

As with many Amazonian tribal plant history and legend, curare is prepared by old women. In some traditions, the witch doctor has a monopoly of the business, but generally, wise old men get together to brew a batch. Extra curare was usually carried by tribal members in a gourd or calabash, and stored with weapons.

Medicinal Uses:

The active ingredient in “curaré”, D-tubocurarine, is used in medicine. Brazilians consider the root a diuretic, and use it internally in small quantities for madness and dropsy, and externally for bruises. It is also used for edema, fever, and kidney stones.

Curare is an alkaloid, and acts as a neuromuscular blocking agent to produce paralysis in muscles. It first affects the muscles of the toes, ears, and eyes, then those of the neck, arms and legs, and finally, those involved in breathing. In fatal doses, death is caused by respiratory paralysis. Curare must get into the blood system for it to work. It doesn’t hurt to eat something killed by a poisoned curare arrow, for instance.

The therapeutical employment of curare has been suggested in certain severe and obstinate spasmodic affections, as in epilepsy, chorea, hydrophobia, and, more particularly, in tetanus. It is used by subcutaneous injections of its filtered aqueous solution, thus: Add curare 1 grain, to distilled water 24 minims; dissolve, let the solution stand 48 hours, and filter; of this, from 2 minims (1/12 grain) to 6 minims (1/4 grain) may be used at one injection, carefully repeating the injections until relaxation of the muscles has been effected. Curarine, dissolved in water, with a few drops of sulphuric acid added, to facilitate its solution, is to be used in still smaller doses—from the 1/240 to the 1/120 part of a grain. It is doubtful whether this agent will ever come into general use as a medicinal remedy; at least, not so long as other medicines are known in which greater confidence can be placed. The diversity of action, attributable, in some instances, to its difference of composition, in others to its inertness, or to its highly active qualities, render it an uncertain, as well as an unsafe, remedy.

It is used in modern medicine primarily as an auxiliary in general anesthesia, frequently with cyclopropane, especially in abdominal surgery. Upon injection, curare acts as a neuromuscular blocking agent to produce flaccidity in striated (striped) muscle (it competes with acetylcholine at the nerve ending, preventing nerve impulses from activating skeletal, or voluntary, muscles). It first affects the muscles of the toes, ears, and eyes, then those of the neck and limbs, and, finally, those involved in respiration. In fatal doses, death is caused by respiratory paralysis.
Practitioners commonly rely on velvet leaf as an excellent natural remedy for menstrual difficulties, including cramping and pain, premenstrual syndrome (PMS), excessive bleeding, and fibroid tumors. Its ability to curb excessive menstrual bleeding very quickly can be quite remarkable. It is often employed in overall female balancing formulas, in kidney formulas (for its diuretic and smooth-muscle relaxant effects), and, in combination with other plants, in heart tonics and hypertension remedies. It is also considered effective against malaria, fever, hepatic ailments, gastric ulcers, diabetes, anemia, high cholesterol, cerebral tonic, fever, typhoid, stomach ulcers, pain killer, chronic inflammation of the urinary passages, good diuretic, etc. In North American herbal medicine, velvet leaf is used for many of the same conditions as in South America as well as for inflammation of the testicles and minor kidney problems. Pereira root also acts as an antiseptic to the bladder and is therefore employed for the relief of chronic inflammation of the urinary passages. It is also a good diuretic. The decoction of the stems and roots mixed with wild bee honey is used to treat sterile women. Root decoction used for post-menstrual hemorrhages, the alcoholic maceration, for rheumatism. Macerated leaves, bark and root, mixed with rum, are used by as aphrodisiac. Root decoction used as a cardio tonic, anti-anemic, anti-malarial. One tribe use a leaf decoction for fever and another use the decoction of the bark and stem as a dental analgesic. Some Ecuadorian tribes use the leaf decoction for conjunctivitis and snakebite. Others use the root tea for difficult delivery and nervous or weak children with colic. Also used in homeopathy, in the form of a mother tincture.

Abutua is a very useful herb for women’s affections. Its antispasmodic action makes it influential in treating cramps, painful menstruation and pre and post-natal pain. Brazilian Indian women have for centuries valued its analgesic powers, and the satchels of almost all midwives contain the root of this plant. Helpful for menstrual cramps and difficult menstruation, pre- and post-natal pain Aids poor digestion, drowsiness after meals and constipation.

Disclaimer:The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

Resources:
http://www.blueplanetbiomes.org/curare.htm
http://ezinearticles.com/?Rainforest-Plants—Curare&id=1030007
http://www.britannica.com/EBchecked/topic/146779/curare

http://www.henriettesherbal.com/eclectic/kings/curare.html

http://www.herbnet.com/Herb%20Uses_UZ.htm

 

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Positive thinking

Working with a Larger Energy

Going with the Flow ……..FLOWING RIVER
The expression going with the flow is a metaphor that applies to navigating a river. When we go with the flow, we follow the current of the river rather than push against it. People who go with the flow may be interpreted as lazy or passive, but to truly go with the flow requires awareness, presence, and the ability to blend one’s own energy with the prevailing energy. Going with the flow doesn’t mean we toss our oars into the water and kick back in the boat, hoping for the best. Going with the flow means we let go of our individual agenda and notice the play of energy all around us. We tap into that energy and flow with it, which gets us going where we need to go a whole lot faster than resistance will.

Going with the flow doesn’t mean that we don’t know where we’re going; it means that we are open to multiple ways of getting there. We are also open to changing our destination, clinging more to the essence of our goal than to the particulars. We acknowledge that letting go and modifying our plans is part of the process. Going with the flow means that we are aware of an energy that is larger than our small selves and we are open to working with it, not against it.

Many of us are afraid of going with the flow because we don’t trust that we will get where we want to go if we do. This causes us to cling to plans that aren’t working, stick to routes that are obstructed, and obsess over relationships that aren’t fulfilling. When you find yourself stuck in these kinds of patterns, do yourself a favor and open to the flow of what is rather than resisting it. Trust that the big river of your life has a plan for you and let it carry you onward. Throw overboard those things that are weighing you down. Be open to revising your maps. Take a deep breath and move into the current.

Source: Daily Om

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