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Herbs & Plants

Myrica cerifera

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Botanical Name : Myrica cerifera
Family: Myricaceae
Genus: Myrica
Species: M. cerifera
Kingdom: Plantae
Order: Fagales

Synonyms : Cerothamnus arborescens, Cerothamnus cerifer, Morella cerifera, Myrica mexicana, Myrica pumila.

Common Names :Wax Myrtle – Bayberry Wild Cinnamon, Southern Bayberry, Wax Myrtle, Southern Wax Myrtle (Southern)  Bayberry, Candleberry, Bayberry tree, and Tallow shrub.

Habitat : Myrica cerifera  is native to South-eastern N. America. Possibly naturalized in S. England. It grows in the  thickets on sandy soil near swamps and marshes, also on dry arid hills in which situation it is often only a few centimetres tall..

Description:
Myrica cerifera is a small tree or large shrub, and is adaptable to many habitats. It grows naturally in wetlands, near flowing bodies of water, sand dunes, fields, hillsides, pine barrens, and in both needleleaf and mixed-broadleaf forests. Specimens in drier and sandier areas are shrub-like, have rhizomes and smaller leaves than usual. Specimens in wetter areas are more tree-like with bigger leaves. However, these two forms are not clear-cut, with many intermediate forms. It is found in various habitats ranging from Central America to Delaware and Maryland in the United States. However, the plant can be successfully cultivated as far north as southern Connecticut and Long Island on the U.S. east coast. It also grows in Bermuda and the Caribbean. In terms of succession, M. cerifera is often one of the first plants to colonize an area.

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M. cerifera is an evergreen. The leaves are long, and have leathery textures and serrated edges. They contain aromatic compounds. The leaves are glandular.

This plant is dioecious. Male flowers have three or four stamens, and are surrounded by short bracts. The flowers are borne on catkins. The female flowers develop into fruit, which are globular and surrounded by a natural wax-like coating. All flowers are borne in inflorescences. The species flowers in late winter to spring, and female specimens bear fruit in late summer or fall. No endosperm is present on the seeds. M. cerifera can also reproduce clonally through runners.

The fruit is a source of food for a lot of bird species, including the Northern Bobwhite Quail and the Wild Turkey. In winter, the seeds are important foods for the Carolina Wren and species of Tree Sparrow. To a point, M. cerifera will also provide habitat for the Northern Bobwhite Quail. Birds digestive systems’ remove the wax from the fruit, which a prerequisite for germination.

This plant’s roots possess root nodules. These are home to a symbiotic species of actinomycotal fungus, which fixes nitrogen at a faster rate than legumes.

M. cerifera, or rather its shoot, cannot handle wildfires well. Indeed, since the leaves, stem, and branches contain flammable aromatic compounds, a specimen of M. cerifera is a fire hazard. For that reason, a wildfire will often kill the shoot. Only a very small or transient fire will do less. In that case, only the most recent primary growth may be incinerated. In contrast to the weakness of its shoot, M. cerifera’s root system is fire-resistant. As of 1991, no known fire has killed this plant’s roots. However, this plant will not survive shoot destruction indefinitely. Three consecutive years of shoot destruction may kill all plants affected. If this does not happen, this species will regrow a shoot. This is most rapid in the first season after a fire.

Cultivation:
Landscape Uses:Border, Erosion control, Screen, Seashore, Specimen. Prefers a moist soil. Grows well in an open position in a well-drained soil in sun or light shade. Thrives in any ordinary garden soil according to one report whilst another says that it thrives in an acid soil. Prefers a lime-free loamy or peaty soil. Plants can be evergreen in areas with warmer winters than in Britain. Some reports say that the plant is dioecious whilst others say it is monoecious. It is most likely that both forms exist. A polymorphic species, there are some named forms. ‘Myda’ is a large-fruited female form of low growth. The fruit is covered with a deposit of wax that has a balsamic odour. The fruits can hang on the plant for several years. Closely related to M. pensylvanica, with which it hybridizes. Plants in this genus are notably resistant to honey fungus. Many species in this genus have a symbiotic relationship with certain soil micro-organisms, these form nodules on the roots of the plants and fix atmospheric nitrogen. Some of this nitrogen is utilized by the growing plant but some can also be used by other plants growing nearby. Special Features:Attracts birds, North American native, Fragrant foliage, Naturalizing, Wetlands plant, Attracts butterflies, Inconspicuous flowers or blooms.

Propagation: 
Seed – best sown as soon as it is ripe in the autumn in a cold frame. Stored seed germinates more freely if given a 3 month cold stratification and then sown in a cold frame. Germination is usually good. Prick out the seedlings into individual pots when they are large enough to handle and grow them on in the cold frame for the first winter. Plant out in late spring or early summer. Cuttings of half-ripe wood, 5 – 8cm with a heel, July/August in a frame. Pot up and overwinter in a cold frame then plant out in late spring or early summer. Fair to good percentage. Layering in spring

Edible Uses:
Edible Parts: Fruit.
Edible Uses: Condiment; Tea.

Fruit – raw or cooked. The fruit is about 3mm in diameter with a large seed. There is very little edible flesh and the quality is poor. Leaves and berries are used as a food flavouring. They make an aromatic, attractive and agreeable substitute for bay leaves, and can be used in flavouring soups, stews etc. The dried leaves are brewed into a robust tea

Medicinal Uses:
Bayberry root bark is the part used in herbalism. The plant contains several organic compounds, including: triterpenes such as myricadiol, taraxerol, and taraxerone, as well as chemicals such as different flavonoids, tannins, resins, gums, and phenols. These compounds have varying effects. Myricadiol has a slight impact on levels of potassium and sodium, while a substance called myricitrin has antibiotic properties.

A key herb in the Thomsonian system of medicine, being the main astringent used for “any stomach or bowel derangement, particularly after fevers.”   Internally used for fevers, colds, influenza, excess mucus, diarrhea, colitis, excessive menstruation, and vaginal discharge.  Externally for sore throat, ulcers, sores, itching skin conditions, dandruff and hair loss.  Bayberry is commonly used to increase circulation, stimulate perspiration, and keep bacterial infections in check. Colds, flu, coughs, and sore throats benefit from treatment with this herb as a hot decoction.  It helps to strengthen local resistance to infection and to tighten and dry mucous membranes.  An infusion is helpful for strengthening spongy gums, and a gargle is used for sore throat.  Bayberry’s astringency helps intestinal disorders such as irritable bowel syndrome and mucous colitis. It increases circulation to the area while acting to tone tissues involved. An infusion can also help treat excess vaginal discharge.  A paste of the powdered root bark may be applied onto ulcers and sores.  The powdered bark has been used as a snuff for congested nasal passages.  It has been used to treat post-partum hemorrhage and taken internally and used as a douche is recommended for excessive menstruation and leucorrhea.  It is used as a poultice to soothe varicose veins. Myricadiol has a mild effect on potassium and sodium levels.  Myricitrin is antibacterial and encourages the flow of bile.  The powder is strongly sternutatory and excites coughing. Water in which the wax has been ‘tried,’ when boiled to an extract, is regarded as a certain cure for dysentery, and the wax itself, being astringent and slightly narcotic, is valuable in severe dysentery and internal ulcerations. The leaves have provided vitamin C for curing scurvy.

Bayberry has a history of medicinal use. The Choctaw boiled and used the result as a treatment for fevers. Bayberry was eventually adopted as a medicinal plant, but only in the South. In 1722, it was reported that colonists in Louisiana drank a mixture of wax and hot water to treat severe dysentery.   Bayberry was reported in an account from 1737 as being used to treat convulsions, colic, palsy, and seizures. Starting in the early 19th century, a herbalist called Samuel Thompson recommended this plant for producing “heat” within the body and as a treatment for infectious diseases and diarrhea. That use of bayberry waned later in the 19th century, in favor of using it for a variety of ailments, including a topical use for bleeding gums. For twenty years starting in 1916, bayberry root bark was listed in the American National Formulary.

Medicinal use of Bayberry has declined since its peak in popularity in the 19th century. The plant is still used today in the treatment of fever, diarrhea, and a few other ailments. The chemical myricitrin has anti-fever properties. In addition, that chemical, along with the tannins, has anti-diarrheal properties. The myricitrin works as an antibiotic, while the tannins have astringent properties.

In general, either a decoction or a tincture is used. Infusions and a topical paste have also been used.

Pregnant women should not use Bayberry. In addition, tannin action relating to cancer is unclear, with studies indicating both pro and anti-cancer effects. Bayberry, just like any other medicinal plant, should only be used under the supervision of a physician

Other Uses:
Ornamental

Myrica cerifera finds use in gardening and horticulture. It has been commonly purported to grow in American hardiness zones of 11 to 7b. However, this is an old, conservative estimate; in recent years, plants have performed well along the east coast as far north as zone 6b in northern Rhode Island. M. pensylvanica substitutes for M. cerifera in areas colder than zone 6. Since the species is adaptable, it will tolerate many conditions, although it has a need for frequent pruning. It can handle abuse from bad pruning, however. The species has at least four cultivars. Those dubbed Fairfax, Jamaica Road, and Don’s Dwarf differ from the “typical” specimen in habit and form. The latter two are also resistant to leaf spot. Var. pumila is a dwarf cultivar

Candles;

Southern Bayberry’s fruits are a traditional source of the wax for those old-fashioned Christmas decorations called bayberry candles.  The wax was extracted by boiling the berries, and skimming off the floating hydrocarbons. The fats were then boiled again and then strained. After that the liquid was usable in candle making, whether through dipping or molding. Southern Bayberry is not the only plant usable for making bayberry candles, however. Its close relatives are also usable.

Southern Bayberry and its relatives have largely been supplanted in candlemaking by substitutes made from paraffin. The substitute candles have artificial colors and scents that create candles that look and smell similar to natural ones

Disclaimer:
The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

Resources:
http://en.wikipedia.org/wiki/Myrica_cerifera
http://www.herbnet.com/Herb%20Uses_AB.htm

http://www.ag.auburn.edu/hort/landscape/dbpages/233.html

http://www.sbs.utexas.edu/bio406d/images/pics/myr/myrica_cerifera.htm

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If You’re in Pain, Think UTI

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Pain while passing urine, a desire to urinate every few minutes, an inability to pass urine despite the urge, high-coloured, cloudy urine, abdominal pain, high fever, shivering and vomiting — a few or all of these are symptoms of an infection somewhere along the urinary tract. In the elderly, the only symptom may be a change in mental status. In men, the pain may be felt in the rectal area. In children, after a period of dryness, bedwetting may recur. In babies, the temperature can fall instead of rise, and there may be jaundice. Almost 25 per cent of visits to a physician is due to this very common infection.
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Urinary tract infection (UTI) affects all age groups and both sexes. It is much more common in women, because of the shorter urethra, its proximity to the anus, pregnancy (when the uterus obstructs the free flow of urine) and minor trauma during sexual intercourse. Thirty five per cent of women have one episode of UTI before the age of 30. Men tend to develop UTI if their prostrate gland is enlarged as this obstructs the flow of urine. In both sexes kidney stones, structural abnormalities of the urinary tract, diabetes or lack of immunity (HIV, cancer medication) can increase susceptibility to infection. Pregnant women can develop asymptomatic UTI with bacteria detected in their urine on routine examination. This condition, called “asymptomatic bactinuria” of pregnancy, needs to be treated.
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Physicians suspect that UTI exists based on the symptoms. A routine urine examination shows abnormalities like pus cells or blood in the urine. A culture can be done to determine the organism responsible so that the appropriate antibiotic can be administered.

Untreated patients of UTI can sometimes recover spontaneously without treatment in a few months. But the infection can also enter the blood stream, causing potentially fatal septicaemia. The kidneys may become scarred, too. This leads to high blood pressure and kidney failure. During pregnancy, recurrent or chronic UTI or asymptomatic UTI compromises the placental blood supply. This affects the baby’s nutrition, leading to low birth weight and sometimes causing the mother to go into premature labour.

There are several regimens for treating UTI. Depending on the organism and antibiotic, in adult women a three-day course is usually sufficient for mild infection. In most cases and in the case of men, however, a 7-10 or 14-day course is required. Oral medication is usually sufficient. If the infection has affected the kidney, hospitalisation and intravenous medication may be required. It is important to follow the doctor’s instructions and complete the course of antibiotics even if you are symptomatically better. In women, if the symptoms do not respond and there is also white discharge, there may be an underlying pelvic infection. In men, non-responsiveness to treatment may be due to unrecognised prostatitis.

One of the ways to prevent UTI is to drink plenty of water. The urine becomes dilute and the bladder gets flushed regularly. An adult needs around 2.5 litres of water a day. In hot, humid climates and in people who exercise vigorously the requirement may go up to 4-6 litres a day. Also, drink a glass of water before going to bed. Empty the bladder before and after intercourse. Drink a glass of water after intercourse.

A few studies have shown that cranberry juice (available in India, Hindi name karaunda) and blueberry juice (not available) helps reduce the frequency and duration of UTI. This is because the juice contains vitamin C which acidifies the urine. It also contains natural chemicals that make the bladder wall slippery and prevent bacteria from sticking to it and initiating an infection. Other citrus juices and tablets of vitamin C are effective but not as efficient. A tablespoon of home-made curd taken on an empty stomach first thing in the morning naturally repopulates the intestines with “good lactobacillus”. This decreases the likelihood of the growth of disease-causing bacteria in the rectum, from where they can enter the urethra.

The pelvic muscles become lax after childbirth. This increases the possibility of the bladder and uterus descending downwards while straining. “Accidents” with leakage of urine and urgency can also occur.

All these increase the chances of infection. Keegles exercises should be done regularly soon after childbirth. Also while passing urine, consciously stop and start. This tones the pelvic muscles.

Women tend to lean forward while urinating. This position is inefficient as it increases the angle between the bladder and the urethra, creating an obstruction to the flow of urine. Women should consciously lean backwards. Also, when the area is being washed after urination or passing motion, wash from front to back. This decreases the likelihood of contamination of the urethra with rectal bacteria

Source: The Telegraph ( Kolkata, India)

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Herbs & Plants

Baobab(Adansonia digitata)

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Botanical Name : Adansonia digitata
Family: Malvaceae
Genus: Adansonia
Species: A. digitata
Kingdom: Plantae
Order: Malvales

Common Name :Baobab

Common Vernacular names:
Adansonia digitata is known by many common names, the most common of which is baobab. It is also known as the dead-rat tree (from the appearance of the fruits), monkey-bread tree (the soft, dry fruit is edible), upside-down tree (the sparse branches resemble roots) and cream of tartar tree. In French, it is known as calebassier du Sénégal and arbre de mille ans; in Portuguese as molambeira, imbondeiro, calabaceira and cabacevre; and in Swahili as mbuyu, mkuu hapingwa, mkuu hafungwa and muuyu.

It is called momret in the Tigrigna language of Ethiopia, where it favors lowland areas with moist and well-drained soils, such as the valley of the Tekeze River lowlands, and “kuka” by the Hausa speaking people of West Africa. In Nigeria, it is a very popular tree in the savannahs of the north and its leaves are used to prepare local soup called “miyan kuka”. In Sudan, the tree is called “tabaldi” and its fruit is called “gongu laze”.

Habitat :Adansonia digitata, the baobab, is the most widespread of the Adansonia species on the African continent, found in the hot, dry savannahs of sub-Saharan Africa. It also grows, having spread secondary to cultivation, in populated areas. The northern limit of its distribution in Africa is associated with rainfall patterns; only on the Atlantic coast and in the Sudan does its occurrence venture naturally into the Sahel. On the Atlantic coast this may be due to spreading after cultivation. Its occurrence is very limited in Central Africa and it is found only in the very north of Southern Africa. In Eastern Africa the trees grow also in shrublands and on the coast. In Angola and Namibia the baobabs grow in woodlands, and in coastal regions, in addition to savannahs. Also found in Dhofar region of Oman and Yemen in the Arabian Peninsula, Asia. This tree is also found in India, particularly in the dry regions of the country

Description:
The trees usually grow as solitary individuals, and are large and distinctive trees on the savannah, in the scrub, and near settled areas, with some large individuals living to well over a thousand years of age. The tree bears very large, heavy white flowers. The showy flowers are pendulous with a very large number of stamens. They carry a carrion scent and researchers have shown that they appear to be primarily pollinated by fruit bats of the subfamily Pteropodinae. The fruits are filled with pulp that dries, hardens, and falls to pieces which look like chunks of powdery, dry bread.

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The African baobab‘s fruit is 6 to 8 inches or 15 to 20 centimetres long. It contains 50% more calcium than spinach, is high in anti-oxidants, and has three times the vitamin C of an orange. It is sometimes called a superfruit. The leaves can be eaten as relish, while the fruit dissolved in milk or water can be used as a drink. The seeds also produce edible oil.

In 2008, the European Union approved the use and consumption of baobab fruit as an ingredient in smoothies and cereal bars.

The United States Food and Drug Administration granted generally recognized as safe status to baobab dried fruit pulp as a food ingredient in 2009.

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It’s large green or brownish fruits resemble gourd-like capsules that are around 6-8 inches in length. These capsules contain a soft whitish fruit pulp that has the appearance of powdery bread and kidney shaped seeds.

To grow A. digitata from a seed, cutting into the thick seed coat greatly speeds up germination, from months or years to seven days.

The specific epithet digitata refers to the fingers of a hand, which the five leaflets (typically) in each cluster bring to mind.

Edible Uses:
The baobab is a traditional food plant in Africa, but is little-known elsewhere. It has been suggested that the vegetable has the potential to improve nutrition, boost food security, foster rural development, and support sustainable land care

The fruit can be up to 25 centimetres (10 in) long and is used to make a drink

Medicinal Uses:
The bark of this tree has been used traditionally to fight fevers.  The leaves may be an excellent source of mineral salts, especially calcium, phosphor and iron, amino acids and provitamin A. There are aspects of considerable interest which require further trials on man, in order to confirm the properties extolled by traditional medicine.  Baobab products do not pretend to be a miraculous panacea, but can simply contribute to rebalancing and restoring the main functions of the organism and the epidermis, offering well-being and energy. Only 5 g a day are beneficial to maintain the state of well-being of the organism, since it increases the resistance to viruses (such as flu and herpes), regularizes the intestine, glycemia and the blood cholesterol values, gives strength, energy and resistance, rebalances mood swings, alleviates menstrual pains, and is anti-anemic, febrifugal and anti-inflammatory. Its beneficial properties may also be applied to obtain a healthy skin and to tackle the effects of premature ageing by virtue of the antioxidant, softening, smoothing and elasticizing properties.

The bark, which contains several flavonols, has been sold commercially in Europe under the name ‘cortex cael cedra’, as a fever treatment, and substitute for cinchona bark.

The off-white, powdery substance inside the fruit shell is apparently rich in ascorbic acid. It is this white powdery substance which is soaked in water to provide a refreshing drink somewhat reminiscent of lemonade. This drink is also used to treat fevers and other complaints.

Medicinally, it has many applications. The pulp is consumed to treat fever, diarrhea, malaria, hemoptysis and scorbutic complaints (vitamin C deficiency). The bark and leaves are also useful in the treatment of fever, and are reported to have anti-inflammatory and diaphoretic properties. The seed is either pulped and applied externally, or drink in water, to cure gastric, kidney and joint diseases. In the Kalahari, San bushmen use the seeds as an antidote to Strophanthin, a common plant-derived arrow poison.

Disclaimer:
The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.

Resources:
http://www.herbnet.com/Herb%20Uses_AB.htm
http://en.wikipedia.org/wiki/Adansonia_digitata
http://www.tarcherbooks.net/?tag=baobab-tree

http://www.madagascar-library.com/r/833.html

http://www.natural-health-and-home-business.com/Baobab.html

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Will Sleeping on Your Side Reduce Snoring?

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Snorers are often told to sleep on their sides rather than on their backs. This is because if you are lying on your side, the base of your tongue will not collapse into the back of your throat, obstructing breathing.
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However, for some snorers, changing sleep position may not make a difference. There are two types of snorers — those who snore when sleeping on their backs, and those who snore in every position.

According to the New York Times:
“… [W]eight plays a major role. In one large study, published in 1997, patients who snored or had breathing abnormalities only while sleeping on their backs were typically thinner, while their nonpositional counterparts usually were heavier … But that study also found that patients who were overweight saw reductions in the severity of their apnea when they lost weight.”

THE BOTTOM LINE :Sleeping on your side can help reduce snoring, though in people who are overweight, it may not make much difference without weight loss.

Resources:
*New York Times April 18, 2011
*Harefuah May 2009; 148(5):304-9, 351, 350
*Chest September 1997; 112(3):629-39

*http://healthmad.com/health/best-ways-that-will-help-you-stop-snoring-3-very-effective-ways/

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Ailmemts & Remedies

Haemochromatosis

Definition:
Haemochromatosis is a disease caused by excess iron in the body.

Iron is needed in the diet to maintain good health, particularly for making red blood cells that carry oxygen around the body. These red blood cells contain large amounts of iron.

Lack of iron can cause anaemia, but excessive iron is toxic. The body has few ways of disposing of unwanted iron, so it builds up in tissues causing damage and disease.

Haemochromatosis – or genetic haemochromatosis (GH) – is a disorder that causes the body to absorb an excessive amount of iron from the diet.

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We can only use a limited amount of iron and any excess is deposited around the body. This accumulates mainly in the liver, but can also affect the heart, pancreas and pituitary gland, damaging these vital body organs and resulting in a deterioration of their functional capacity.

Haemochromatosis is more common in Caucasian or white populations, with about 1 in 300 to 1 in 400 affected. About half that number are affected in black populations.

Men are more likely to have hereditary haemochromatosis and suffer from it at an earlier age, as women regularly lose iron in menstruation or use stores in pregnancy.

Symptoms:
Although haemochromatosis and the potential for the condition to cause problems is present from birth, symptoms don’t usually become apparent until middle age.

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Common symptoms that might be noticed then include:

•weakness, tiredness and lack of energy
•joint pain and stiffness – particularly in the hands and fingers
•a tanned or bronzed appearance of the skin
•impotence in men
•shrinking of testicles
•weight loss
•abdominal pain
.
Later, more serious symptoms may develop including:

•diabetes
•arthritis
•heart problems
•enlargement or damage to the liver

Clinical presentation:
Organs commonly affected by haemochromatosis are the liver, heart, and endocrine glands.

Haemochromatosis may present with the following clinical syndromes:

*Cirrhosis of the liver
*Diabetes due to pancreatic islet cell failure
*Cardiomyopathy
*Arthritis (iron deposition in joints)
*Testicular failure
*Tanning of the skin

Causes:
The causes can be distinguished between primary cases (hereditary or genetically determined) and less frequent secondary cases (acquired during life). People of Celtic (Irish, Scottish, Welsh) origin have a particularly high incidence of whom about 10% are carriers of the gene and 1% sufferers from the condition.

Primary haemochromatosis:
The fact that most cases of haemochromatosis were inherited was well known for most of the 20th century, though they were incorrectly assumed to depend on a single gene. The overwhelming majority actually depend on mutations of the HFE gene discovered in 1996, but since then others have been discovered and sometimes are grouped together as “non-classical hereditary haemochromatosis”, “non-HFE related hereditary haemochromatosis”, or “non-HFE haemochromatosis

It is thought to be mainly caused by a mutation of a gene called HFE, which probably allows excess iron to be absorbed from the diet. This mutation is known as C282Y and to develop haemochromatosis you usually need two genes (one from each parent) to be C282Y.

However, not everyone with the mutation may develop the disease, and it may occur if only one C282Y gene is present.

Confusingly, another mutation labelled H63D elsewhere on the HFE gene may occur alone or with C282Y and also influence iron levels.

Other rare mutations may give rise to haemochromatosis, especially in children.

Secondary haemochromatosis:
*Severe chronic haemolysis of any cause, including intravascular haemolysis and ineffective erythropoiesis (haemolysis within the bone marrow).
*Multiple frequent blood transfusions (either whole blood or just red blood cells), which are usually needed either by individuals with hereditary anaemias (such as beta-thalassaemia major, sickle cell anaemia, and Diamond–Blackfan anaemia) or by older patients with severe acquired anaemias such as in myelodysplastic syndromes.
*Excess parenteral iron supplements, such as can acutely happen in iron poisoning
*Excess dietary iron
*Some disorders do not normally cause haemochromatosis on their own, but may do so in the presence of other predisposing factors. These include cirrhosis (especially related to alcohol abuse), steatohepatitis of any cause, porphyria cutanea tarda, prolonged haemodialysis, post-portacaval shunting.

Risk Factors:
The onset of hereditary haemochromatosis usually occurs between the ages of 30 and 60 as the build up of iron takes years.

However, a rapid form of the disease does affect children. If left untreated excess iron builds up in the organs especially the liver, heart and pancreas. This may cause heart or liver failure, which can be fatal.

Diagnosis:
There are several methods available for diagnosing and monitoring iron loading including:

*Serum ferritin
*Liver biopsy
*HFE
*MRI

Serum ferritin is a low-cost, readily available, and minimally invasive method for assessing body iron stores. However, the major problem with using it as an indicator of iron overload is that it can be elevated in a range of other medical conditions unrelated to iron levels including infection, inflammation, fever, liver disease, renal disease, and cancer. Also, total iron binding capacity may be low, but can also be normal.

The standard of practice in diagnosis of hemochromatosis was recently reviewed by Pietrangelo. Positive HFE analysis confirms the clinical diagnosis of hemochromatosis in asymptomatic individuals with blood tests showing increased iron stores, or for predictive testing of individuals with a family history of hemochromatosis. The alleles evaluated by HFE gene analysis are evident in ~80% of patients with hemochromatosis; a negative report for HFE gene does not rule out hemochromatosis. In a patient with negative HFE gene testing, elevated iron status for no other obvious reason, and family history of liver disease, additional evaluation of liver iron concentration is indicated. In this case, diagnosis of hemochromatosis is based on biochemical analysis and histologic examination of a liver biopsy. Assessment of the hepatic iron index (HII) is considered the “gold standard” for diagnosis of hemochromatosis.

MRI is emerging as an alternative to liver biopsy for measuring liver iron loading. For measuring liver iron concentrations, R2-MRI (also known as FerriScan)  has been validated and is coming into use in medical centers. It is not recommended in practice guidelines at this time

Prognosis:
A third of those untreated develop hepatocellular carcinoma.

Treatment:
Routine treatment in an otherwise-healthy person consists of regularly scheduled phlebotomies (bloodletting). When first diagnosed, the phlebotomies may be fairly frequent, perhaps as often as once a week, until iron levels can be brought to within normal range. Once iron and other markers are within the normal range, phlebotomies may be scheduled every other month or every three months depending upon the patient’s rate of iron loading.

For those unable to tolerate routine blood draws, there is a chelating agent available for use. The drug Deferoxamine binds with iron in the bloodstream and enhances its elimination via urine and faeces. Typical treatment for chronic iron overload requires subcutaneous injection over a period of 8–12 hours daily. Two newer iron chelating drugs that are licensed for use in patients receiving regular blood transfusions to treat thalassemia (and, thus, who develop iron overload as a result) are deferasirox and deferiprone.

Haemochromatosis is treated by:

•Reducing the amount of iron absorbed by the body – patients are advised to avoid iron-rich foods and alcohol.
•Removing excess iron from the body by removing blood from the body (venesection therapy or phlebotomy). Initially this may involve removing a unit of blood a week (sometimes for many months) until iron levels in the blood are normal. Then most people can be kept stable by removing a unit of blood every 2-3 months.

If phlebotomy is started before liver damage occurs the outlook is good, and the affected person can expect to live an otherwise normal life.

Acquired haemochromatosis is normally treated by a drug that binds iron and allows it to be excreted from the body.

Associated problems such as heart failure and diabetes are treated as appropriate.

Good advice:-
*Limit the amount of iron in your diet.
*Eating red or organ meats (such as liver) is not recommended.
*Iron supplements should also be avoided, including iron combined with other multivitamins.
*Vitamin C increases iron absorption from the gut and intake should also be limited.
*Avoid excess alcohol as this may make liver disease worse

Future prospects:
Your prospects largely depend on the stage at which the disease was diagnosed. Symptoms of tiredness and general weakness often improve, but joint problems may not.

Abdominal pain and liver enlargement can also lessen or disappear, and heart function may also improve with treatment.

However, liver cirrhosis is irreversible and a liver transplant may be required.

Patients with liver disease are also usually monitored for liver cancer, which can be a long-term complication.

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose.

Resources:
http://www.bbc.co.uk/health/physical_health/conditions/haemochromatosis1.shtml
http://en.wikipedia.org/wiki/Iron_overload
http://www.netdoctor.co.uk/diseases/facts/haemochromatosis.htm

https://runkle-science.wikispaces.com/Haemochromatosis

http://www.ironxs.com.au/the-symptoms-of-haemochromatosis.html

http://www.goldbamboo.com/topic-t1404-a1-6Haemochromatosis.html

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