Categories
Diagnonistic Test

Abdominal CT Scan

[amazon_link asins=’363925189X,1483474747,3659399264,B004GXAT8K,B01K93LHC2,3319483463,B005LB038C,B004CYE9WA,B00G5RRTQU’ template=’ProductCarousel’ store=’finmeacur-20′ marketplace=’US’ link_id=’7a7b10f3-04fe-11e8-badb-35079666f77f’]

Introduction:
An abdominal CT scan is an imaging method that uses x-rays to create cross-sectional pictures of the belly area. CT stands for computed tomography.
CT scans are pictures taken by a specialized x-ray machine. The machine circles your body and scans an area from every angle within that circle. The machine measures how much the x-ray beams change as they pass through your body. It then relays that information to a computer, which generates a collection of black-and-white pictures, each showing a slightly different “slice” or cross-section of your internal organs. Because these “slices” are spaced only about a quarter-inch apart, they give a very good representation of your internal organs and other structures. Doctors use CT scans to evaluate all major parts of the body, including the abdomen, back, chest, and head.

..CLICK & SEE

CT stands for computerized tomography. In this procedure, a thin X-ray beam is rotated around the area of the body to be visualized. Using very complicated mathematical processes called algorithms, the computer is able to generate a 3-D image of a section through the body. CT scans are very detailed and provide excellent information for the physician.

A CT scan is an excellent way to view the organs inside your abdomen. It is especially useful for looking at solid organs, such as the liver, pancreas, spleen, kidneys, and adrenal glands. It is also excellent for viewing the large blood vessels that pass through the abdomen (the aorta and vena cava) and for finding lymph nodes in the abdomen. Organs that can change their shape when they are empty or full, such as stomach and intestines, are harder for a CT scan to evaluate well, because it is sometimes difficult for a doctor to tell for sure if they are abnormal. Often the CT can give some information about these organs, though. Abdominal CT scans are often used to look for signs of inflammation or infection inside the abdomen in different organs, to look for cancer, or to look for injury to one or another internal organ.

A CT scan provides a better picture of internal organs than traditional x-rays. The benefits of an abdominal CT scan usually far outweigh the risks of radiation exposure.

How the Test is Performed
You will be asked to lie on a narrow table that slides into the center of the CT scanner. Usually, you will lie on your back with your arms raised above the head.

The health care provider may inject a dye into one of your veins. This helps certain diseases and organs show up better on the images.

Once inside the scanner, the machine’s x-ray beam rotates around you. Small detectors inside the scanner measure the amount of x-rays that make it through the abdomen. A computer takes this information and creates several individual images, called slices.

You must be still during the exam, because movement causes blurred images. You may be told to hold your breath for short periods of time.

The actual scan time only takes a few minutes, although the entire procedure usually takes much longer.
A CT scan is an excellent way to view the organs inside your abdomen. It is especially useful for looking at solid organs, such as the liver, pancreas, spleen, kidneys, and adrenal glands. It is also excellent for viewing the large blood vessels that pass through the abdomen (the aorta and vena cava) and for finding lymph nodes in the abdomen. Organs that can change their shape when they are empty or full, such as stomach and intestines, are harder for a CT scan to evaluate well, because it is sometimes difficult for a doctor to tell for sure if they are abnormal. Often the CT can give some information about these organs, though. Abdominal CT scans are often used to look for signs of inflammation or infection inside the abdomen in different organs, to look for cancer, or to look for injury to one or another internal organ.

Why the Test is Performed
An abdominal CT rapidly creates detailed pictures of the belly area. The test may be used to:

*Study blood vessels
*Identify masses and tumors, including cancer
*Look for infections, kidney stones, or appendicitis
.How to Prepare for the Test
If you are having an abdominal CT scan, you might have to fast 2–4 hours before your test. You also may have to drink a large quantity of oral contrast, a fluid that will show up on the CT scan and help define the lining of some internal organs.

Tell your doctor if you’re allergic to x-ray contrast dyes, may be pregnant, or have diabetes and take insulin. Insulin can cause hypoglycemia after missing a meal. or have had difficulty with previous CT scans.

If contrast or sedation is used, you may also be asked not to eat or drink anything for 4-6 hours before the test.

Since x-rays have difficulty passing through metal, you will be asked to remove jewelry and wear a hospital gown during the study.

What happens when the test is performed?
The test is done in the radiology department of a hospital or in a diagnostic clinic. You wear a hospital gown and lie on your back on a table that can slide back and forth through the donut-shaped CT machine. A technician or other health care professional inserts an IV and injects more contrast dye through it. This dye outlines blood vessels and soft tissue to help them show up clearly on the pictures.

The technologist moves the table with a remote control to enable the CT machine to scan your body from all of the desired angles. You will be asked to hold your breath for a few seconds each time a new level is scanned. The technologist usually works the controls from an adjoining room, watching through a window and sometimes speaking to you through a microphone. A CT scan takes about 30–45 minutes. Although it’s not painful, you might find it uncomfortable if you don’t like to lie still for extended periods.

How the Test Will Feel
The x-rays are painless. Some people may have discomfort from lying on the hard table.

Contrast give through an IV may cause a slight burning sensation, a metallic taste in the mouth, and a warm flushing of the body. These sensations are normal and usually go away within a few seconds.

Risk Factors:-
There are a few small risks. The contrast dye used in the test can damage your kidneys, especially if they are already impaired by disease.However, some newer dyes are less likely to cause kidney injuries. If kidney damage does occur, this is usually temporary, although in some rare cases it becomes permanent. If you are allergic to the dye used in the procedure, you may get a rash or your blood pressure may drop enough to make you feel faint until you get treatment. As with x-rays, there is a small exposure to radiation. The amount of radiation from a CT scan is greater than that from regular x-rays, but it’s still too small to be likely to cause harm unless you’re pregnant.

An abdominal CT scan is usually not recommended for pregnant women, because it may harm the unborn child. Women who are or may be pregnant should speak with their health care provider to determine if ultrasound can be used instead.

CT scans and other x-rays are strictly monitored and controlled to make sure they use the least amount of radiation. CT scans do create low levels of ionizing radiation, which has the potential to cause cancer and other defects. However, the risk associated with any individual scan is small. The risk increases as numerous additional studies are performed.

In some cases, a CT scan may still be done if the benefits greatly out weigh the risks. For example, it can be more risky not to have the exam, especially if your health care provider thinks you might have cancer.

The most common dye used is iodine based. A person who is allergic to iodine may have nausea, sneezing, vomiting, itching, or hives. Rarely, the dye may cause anaphylaxis (a life-threatening allergic response).

Results:-
What Abnormal Results Mean

The CT scan may show the following:

*Abdominal aortic aneurysm
*Abscesses
*Acute bilateral obstructive uropathy
*Acute cholecystitis
*Acute unilateral obstructive uropathy
*Addison’s disease
*Amebic liver abscess
*Appendicitis
*Bilateral hydronephrosis
*Bowel wall thickening
*Carcinoma of the renal pelvis or ureter
*Cholangiocarcinoma
*Choledocholithiasis
*Cholelithiasis
*Chronic bilateral obstructive uropathy
*Chronic cholecystitis
*Chronic pancreatitis
*Chronic unilateral obstructive uropathy
*Complicated UTI (pyelonephritis)
*Cystinuria
*Cysts
*Echinococcus
*Enlarged lymph nodes
*Enlarged organs
*Gastrointestinal or bowel obstruction
*Glucagonoma
*Hairy cell leukemia
*Hepatocellular carcinoma
*Histoplasmosis; disseminated
*Hodgkin’s lymphoma
*Islet of Langerhans’ tumor
*Multiple endocrine neoplasia (MEN) II
*Nephrocalcinosis
*Nephrolithiasis
*Non-Hodgkin’s lymphoma
*Ovarian cancer
*Pancreatic abscess
*Pancreatic carcinoma
*Pancreatic pseudocyst
*Pancreatitis
*Pheochromocytoma
*Primary hyperaldosteronism
*Pyelonephritis – acute
*Pyogenic liver abscess
*Renal cell carcinoma
*Retroperitoneal fibrosis
*Sclerosing cholangitis
*Stones (bladder, kidney, liver, gall bladder)
*Testicular cancer
*Tumors
*Unilateral hydronephrosis
*Ureterocele
*Wilms’ tumor
*Wilson’s disease
*Zollinger-Ellison syndrome

Additional conditions under which the test may be performed include the following:-
*Acute renal failure
*Alcoholic liver disease (hepatitis/cirrhosis)
*Atheroembolic renal disease
*Chronic glomerulonephritis
*Chronic renal failure
*Cushing syndrome
*Cushing syndrome caused by adrenal tumor
*Injury of the kidney and ureter
*Medullary cystic kidney disease
*Multiple endocrine neoplasia (MEN) I
*Polycystic kidney disease
*Reflux nephropathy
*Renal artery stenosis
*Renal vein thrombosis
*Skin lesion of histoplasmosis

How long is it before the result of the test is known?
The radiologist can probably give you preliminary results within a day. The formal reading of your CT scan might take another day.

Resources:
https://www.health.harvard.edu/fhg/diagnostics/abdominal-ct-scan.shtml
http://www.nlm.nih.gov/medlineplus/ency/article/003789.htm

Categories
Diagnonistic Test

Chest X-Ray

[amazon_link asins=’B0148JSEPG,0702030465,1455774839,3131442115,9351521729,0470656190,190574059X,0443069220,0443070083′ template=’ProductCarousel’ store=’finmeacur-20′ marketplace=’US’ link_id=’cde0e21b-0506-11e8-8e97-0fc270d5f803′]

Definition:The chest x-ray is the most commonly performed diagnostic x-ray examination. A chest x-ray makes images of the heart, lungs, airways, blood vessels and the bones of the spine and chest.

An x-ray (radiograph) is a noninvasive medical test that helps physicians diagnose and treat medical conditions. Imaging with x-rays involves exposing a part of the body to a small dose of ionizing radiation to produce pictures of the inside of the body. X-rays are the oldest and most frequently used form of medical imaging.

Doctors have used x-rays for over a century to see inside the body in order to diagnose a variety of problems, including cancer, fractures, and pneumonia. During this test, you usually stand in front of a photographic plate while a machine sends x-rays, a type of radiation, through your body. Originally, a photograph of internal structures was produced on film; nowadays, the image created by the x-rays goes directly into a computer. Dense structures, such as bone, appear white on the x-ray films because they absorb many of the x-ray beams and block them from reaching the plate (see Figure 16). Hollow body parts, such as lungs, appear dark because x-rays pass through them. (In some other countries, like the United Kingdom, the colors are reversed, and dense structures are black.)

Back x-rays and chest x-rays are among the most common conventional x-ray tests. You should not have an x-ray if you’re pregnant, because radiation can be harmful to a developing fetus.

A chest x-ray provides black-and-white images of your lungs, ribs, heart, and diaphragm.

CLICK & SEE

Some common uses:
The chest x-ray is performed to evaluate the lungs, heart and chest wall.

A chest x-ray is typically the first imaging test used to help diagnose symptoms such as:

*shortness of breath
*a bad or persistent cough
*chest pain or injury
*fever.
Physicians use the examination to help diagnose or monitor treatment for conditions such as:

*pneumonia
*heart failure and other heart problems
*emphysema
*lung cancer
*other medical conditions.


How should you prepare for the test?

A chest x-ray requires no special preparation.

You may be asked to remove some or all of your clothes and to wear a gown during the exam. You may also be asked to remove jewelry, eye glasses and any metal objects or clothing that might interfere with the x-ray images.

Women should always inform their physician or x-ray technologist if there is any possibility that they are pregnant. Many imaging tests are not performed during pregnancy so as not to expose the fetus to radiation. If an x-ray is necessary, precautions will be taken to minimize radiation exposure to the baby. See the Safety page for more information about pregnancy and x-rays.

You are usually asked to remove all clothing, undergarments, and jewelry above your waist, and to wear a hospital gown.

What does the equipment look like?
The equipment typically used for chest x-rays consists of a wall-mounted, box-like apparatus containing the x-ray film or a special plate that records the image digitally and an x-ray producing tube, that is usually positioned about six feet away.
CLICK & SEE
The equipment may also be arranged with the x-ray tube suspended over a table on which the patient lies. A drawer under the table holds the x-ray film or digital recording plate.

A portable x-ray machine is a compact apparatus that can be taken to the patient in a hospital bed or the emergency room. The x-ray tube is connected to a flexible arm that is extended over the patient while an x-ray film holder or image recording plate is placed beneath the patient.

What happens when the test is performed?
Chest x-rays usually are taken while you are standing. A technician positions you against the photographic plate (which looks like a large board) to obtain the clearest pictures. He or she takes pictures from the front and from one side while asking you to take in a deep breath just before each picture. The technician leaves the room or stands behind a screen while the x-rays are taken.

How does the procedure work?
X-rays are a form of radiation like light or radio waves. X-rays pass through most objects, including the body. Once it is carefully aimed at the part of the body being examined, an x-ray machine produces a small burst of radiation that passes through the body, recording an image on photographic film or a special digital image recording plate.

Different parts of the body absorb the x-rays in varying degrees. Dense bone absorbs much of the radiation while soft tissue, such as muscle, fat and organs, allow more of the x-rays to pass through them. As a result, bones appear white on the x-ray, soft tissue shows up in shades of gray and air appears black.

On a chest x-ray, the ribs and spine will absorb much of the radiation and appear white or light gray on the image. Lung tissue absorbs little radiation and will appear dark on the image.

Until recently, x-ray images were maintained as hard film copy (much like a photographic negative). Today, most images are digital files that are stored electronically. These stored images are easily accessible and are sometimes compared to current x-ray images for diagnosis and disease management.

How is the procedure performed?

Typically, two views of the chest are taken, one from the back and the other from the side of the body as the patient stands against the image recording plate. The technologist, an individual specially trained to perform radiology examinations, will position the patient with hands on hips and chest pressed the image plate. For the second view, the patient’s side is against the image plate with arms elevated.

 

Patients who cannot stand may be positioned lying down on a table for chest x-rays.

You must hold very still and may be asked to keep from breathing for a few seconds while the x-ray picture is taken to reduce the possibility of a blurred image. The technologist will walk behind a wall or into the next room to activate the x-ray machine.

When the examination is complete, you will be asked to wait until the radiologist determines that all the necessary images have been obtained.

The chest x-ray examination is usually completed within 15 minutes.

Additional views may be required within hours, days or months to evaluate any changes in the chest.

What will you experience during and after the procedure?
A chest x-ray examination itself is a painless procedure.

You may experience discomfort from the cool temperature in the examination room and the coldness of the recording plate. Individuals with arthritis or injuries to the chest wall, shoulders or arms may have discomfort trying to stay still during the examination. The technologist will assist you in finding the most comfortable position possible that still ensures diagnostic image quality.
Who interprets the results and how do you get them?
A radiologist, a physician specifically trained to supervise and interpret radiology examinations, will analyze the images and send a signed report to your primary care or referring physician, who will discuss the results with you.

In an emergency, the results of a chest x-ray can be available almost immediately for review by your physician.
What are the benefits vs. risks?
Benefits:

*No radiation remains in a patient’s body after an x-ray examination.
*X-rays usually have no side effects in the diagnostic range.
*X-ray equipment is relatively inexpensive and widely available in emergency rooms, physician offices, ambulatory care *centers, nursing homes and other locations, making it convenient for both patients and physicians.
*Because x-ray imaging is fast and easy, it is particularly useful in emergency diagnosis and treatment.

Risks:

*There is always a slight chance of cancer from excessive exposure to radiation. However, the benefit of an accurate diagnosis far outweighs the risk.

*The chest x-ray is one of the lowest radiation exposure medical examinations performed today. The effective radiation dose from this procedure is about 0.1 mSv, which is about the same as the average person receives from background radiation in 10 days. See the Safety page for more information about radiation dose.

*Women should always inform their physician or x-ray technologist if there is any possibility that they are pregnant. See the Safety page for more information about pregnancy and x-rays.

How long is it before the result of the test is known?
Although digital images may be available immediately, it will take additional time for a doctor to examine and interpret them. You’ll probably get the results later in the day.

A Word About Minimizing Radiation Exposure:
Special care is taken during x-ray examinations to use the lowest radiation dose possible while producing the best images for evaluation. National and international radiology protection councils continually review and update the technique standards used by radiology professionals.

State-of-the-art x-ray systems have tightly controlled x-ray beams with significant filtration and dose control methods to minimize stray or scatter radiation. This ensures that those parts of a patient’s body not being imaged receive minimal radiation exposure.

What are the limitations of Chest Radiography?
The chest x-ray is a very useful examination, but it has limitations. Because some conditions of the chest cannot be detected on an x-ray image, this examination cannot necessarily rule out all problems in the chest. For example, very small cancers may not show up on a chest x-ray. A blood clot in the lungs, a condition called a pulmonary embolism, cannot be seen on chest x-rays.

Further imaging studies may be necessary to clarify the results of a chest x-ray or to look for abnormalities not visible on the chest x-ray.

Click for More Additional Information and Resources: ->
*RadiologyInfo: Radiation Therapy for Lung Cancer

*RTAnswers.org: Radiation Therapy for Lung Cancer

Resources:
https://www.health.harvard.edu/diagnostic-tests/chest-x-ray.htm
http://www.radiologyinfo.org/en/info.cfm?PG=chestrad

Enhanced by Zemanta
Categories
Ailmemts & Remedies Pediatric

Craniosynostosis

Alternative Names:Premature closure of sutures

Definition:
To allow for rapid brain growth, your baby’s skull cap is made up of five bones, held together by a fibrous-like material called “sutures”. Normally, they remain open as long as the brain grows, which gives the brain room needed to grow in all directions.

If any of the sutures close or fuse before the brain has finished growing, the condition known as craniosynostosis occurs. Other terms used to describe this problem include: synostosis, or cranial stenosis. Premature closure can take place before birth or at any time until the brain stops growing.

CLICK & SEE THE PICTURES

Because the brain is growing normally, it will take the path of least resistance which will result in a misshapen head or face.
The skull of an infant is made up of free-floating bones separated by fibers called sutures. This arrangement allows the infant’s head to pass through the birth canal and also enables the skull to grow with the brain in early infancy. Craniosynostosis is a birth defect of the brain characterized by the premature closure of one or more of the fibrous joints between the bones of the skull (called the cranial sutures) before brain growth is complete.Closure of a single suture is most common.
Skull of a newborn

The abnormally shaped skull that results is due to the brain not being able to grow in its natural shape because of the closure. Instead it compensates with growth in areas of the skull where the cranial sutures have not yet closed. The condition can be gene-linked, or caused by metabolic diseases, such as rickets or an overactive thyroid. Some cases are associated with other disorders such as microcephaly (abnormally small head) and hydrocephalus (excessive accumulation of cerebrospinal fluid in the brain).

Causes :
The cause of craniosynostosis is unknown. Which suture is involved determines the abnormal shape of the head.

A person’s genes may play a role in craniosynostosis. The hereditary form often occurs with other defects that can cause seizures, diminished intellectual capacity, and blindness. Genetic disorders commonly associated with craniosynostosis include Crouzon, Apert, Carpenter, Chotzen, and Pfeiffer syndromes.

However, most cases of craniosynostosis occur in a family with no history of the condition and children with craniosynostosis are otherwise healthy and have normal intelligence.

There are different types of craniosynostosis. Sagittal synostosis (scaphocephaly) is the most common type. It affects the main (sagittal) suture on the very top of the head. The early closing forces the head to grow long and narrow, instead of wide. Babies with this type of craniosynostosis tend to have a broad forehead. It is more common in boys than girls.

Frontal plagiocephaly is the next most common form. It is the closure of one side of the suture that runs from ear to ear on the top of the head. It is more common in girls.

Metopic synostosis is a rare form of craniosynostosis that affects the suture close to the forehead. The child’s head shape may be described as trigonocephaly, and the deformity may range from mild to severe.

Symptoms :

The first sign of craniosynostosis is changes in the shape of the head and face . Other features can include :-

*a full or bulging fontanelle (soft spot located on the top of the head)

*sleepiness (or less alert than usual)

*scalp veins may be very noticeable

*increased irritability

*high-pitched cry

*poor feeding

*projectile vomiting

*increasing head circumference

*seizures

*bulging eyes and an inability of the child to look upward with the head facing forward

*developmental delays

Diagnosis:
Craniosynostosis may be congenital (present at birth) or may be observed later, during a physical examination. The diagnosis is made after a thorough physical examination and after diagnostic testing. During the examination, a measurement of the circumference of your child’s head is taken and plotted on a graph to identify normal and abnormal ranges. In addition, the following tests may be ordered:

x-rays of the head – a diagnostic test that uses invisible electromagnetic energy beams to produce images of internal tissues and bones of the head onto film.
computerized tomography scan (Also called a CT or CAT scan.) of the head – a diagnostic imaging procedure that uses a combination of x-rays and computer technology to produce cross-sectional images (often called slices), both horizontally and vertically, of the head.

Treatment:

Treatment for craniosynostosis generally consists of surgery to relieve pressure on the brain and the cranial nerves. The goal of treatment is to reduce the pressure in the head and correct the deformities of the face and skull bones. The optimal time to perform surgery is before the child is 1 year of age since the bones are still very soft and easy to work with. Surgery may be necessary at a much earlier age depending upon the severity of the condition. For some children with less severe problems, cranial molds can reshape the skull to accommodate brain growth and improve the appearance of the head.

Possible Complications :

Craniosynostosis results in head deformity that can be severe and permanent if it is not corrected. Increased intracranial pressure, seizures, and developmental delay can occur.

Prognosis:
The prognosis for craniosynostosis varies depending on whether single or multiple cranial sutures are involved or other abnormalities are present. The prognosis is better for those with single suture involvement and no associated abnormalities. The key to treating craniosynostosis is early detection and treatment. Some forms of craniosynostosis can affect the brain and development of a child. The degree of the problems is dependent on the severity of the craniosynostosis, the number of sutures that are fused, and the presence of brain or other organ system problems that could affect the child.

Prevention:
Be sure to bring your child to well-child visits, so your pediatrician can routinely chart the growth of your infant’s head over time. This will help identify the problem early if it occurs.Persons with hereditary craniosynostosis might consider genetic counseling.

When to Contact a Medical Professional:
Call your health care provider if you think your child’s head has an unusual shape. A referral to a pediatric neurologist or neurosurgeon should follow.
Click to see also:->
Abnormal Head Shapes in Infants
My Baby’s Head is Flat!

Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose

Resources:
KidsGrowth.com
http://www.nlm.nih.gov/medlineplus/ency/article/001590.htm
http://www.craniosynostosis.net/what-is-craniosynostosis.shtml

Enhanced by Zemanta
Categories
News on Health & Science

MEDICINES DON’T HELP BRONCHITIS

[amazon_link asins=’148255898X,B002HJFAXO,B017IY2GY8,B00PYW9BW2,B01M1SVK5B,B07CMHLM3C,B00K3I9MJY,B00W85XIAY,B01A5WMKMS’ template=’ProductCarousel’ store=’finmeacur-20′ marketplace=’US’ link_id=’e158e7ab-8dbf-11e8-ac5d-0d7174c60a20′]

Antibiotics are often prescribed for treatment of bronchitis, but they are mostly useless, since nearly all cases of bronchitis are caused by viruses, not bacteria. A new review published in the New England Journal of Medicine finds that 70 to 80 percent of people with bronchitis are still prescribed antibiotics, which means they may get side effects like abdominal pain, diarrhea and rashes without getting any benefit from the medication. Furthermore, reviewers from Virginia Commonwealth University find that nearly 100 percent of bronchitis patients received a prescription for cough medication, despite the fact that cough medications are also ineffective for bronchitis. Most cases of bronchitis clear up easily in a few days, but people with high fevers, especially those that persist more than a day or two, should consult a doctor.

Source:ABC News

Categories
News on Health & Science

2-Drug process to heal the heart

[amazon_link asins=’B01FOYE4KS,B00TIY69XG,B00PKKR9NG’ template=’ProductCarousel’ store=’finmeacur-20′ marketplace=’US’ link_id=’1b5f0c5b-265c-11e7-90cd-237f39bf0bbd’]

The damaging effects of a heart attack may be reversible, say researchers who have successfully used drugs to boost new heart tissue and blood vessel growth.

Treating the hearts of rats that had experienced simulated heart attacks, the team found the repaired hearts beat as well as undamaged hearts even after several months.

This is a dramatic recovery,”says Felix Engel, paediatrician at the Children’s Hospital in Boston who led the study. “A human with this kind of heart muscle damage would be dead.”

Under normal conditions, when blood flow is prevented from reaching the heart during a heart attack, the tissue dies, forming irreparable scar tissue. To re-grow the damaged areas in rats, Engel and colleagues used two drugs: one that overcomes a natural inhibitor of cell division within the heart; and one that encourages blood vessel growth.

The researchers studied 120 rats, some with heart attacks simulated by permanently closing off one of the coronary arteries that feed the heart muscle. Rats that received both drugs showed the greatest improvements.

Yibin Wang, a physiologist at the University of California, Los Angeles, US, who collaborated with Engel on a preliminary study, praised the new work but questioned some of its claims.

“The bottom line of this study is great,”Wang said, “they found a way to break the barrier of cardiac regeneration. But it’s very challenging to claim all of the benefits they observe are truly due to regeneration.”

Wang noted that heart function began increasing just one day after the heart attack   too soon, in his opinion, to be attributed to regeneration.

He suspects the damaged cells never died, but were protected by the drugs, which were applied at the same time as the simulated attack.

css.php