Botanical Name : Salvia plebeia R. Brown Family: Lamiaceae Genus: Salvia Species: S. plebeia Kingdom: Plantae Order: Lamiales Scientific names :Salvia plebeia R. Brown ,Salvia brachiata Roxb. ,Salvia parviflora Roxb. Common names:Mizo-kouiju (Japanese), Li zhi cao (Chin.),Sage weed (Engl.)
Habitat :Salvia plebeia is native to a wide region of Asia. It grows on hillsides, streamsides, and wet fields from sea level to 2,800 m (9,200 ft) As a weed in and about towns in various provinces at low altitudes.
Salvia plebeia is an annual, hairy herb. Stems are stout, erect, hoary, and 15 to 45 cms in height. Leaves are oblong ovate, 2.5 to 7.5 cms long, and narrowed and pointed at both ends. Spikes are panicled, often fastigiate. Flowers are hardly 6 mm long, lilac or nearly white, occurring in small, very numerous whorls in numerous, slender, panicled, glandular racemes. Calyx is stalked, bell-shaped, and 10 to 12 mm long; the upper calyx-lip is entire, and the lower one obtusely 2-toothed. Corolla-tube is very short, and the included upper lip is short, nearly straight, slightly flattened, and concave. Nutlets are very minute and ellipsoid. CLICK & SEE THE PICTURES You may click to see pictures of Salvia plebeia plant : Constituents:
* Study yielded six compounds: hispidulin-glucoronide, hispidulin-7-O-D-glucoside, 6-methoxy-luteolin-7-glucoside, ß-sitosterol, 2′-hydroxy-5′-methoxybiochanin A and coniferyl aldehyde.
*Study of whole plant yielded: ß-sitosterol, hispidulin, carnosol, rosmadial, ursolic acid, pectolinarigenin, epirosmanol, caffeic acidmethyl ester and scopoletin.
Edible Uses: Flowers and leaves used as condiment.
*Seeds are used in gonorrhea and menorrhage.
*In Bombay, used to increase sexual powers.
*In China, used as anti-inflammatory and for treating urinary tract infections.
Studies :- • Antioxidant: Study yielded six compounds. (See:Constituents) Compounds 3, 4 and 5 ( 6-methoxy-luteolin-7-glucoside, ?-sitosterol, 2?-hydroxy-5?-methoxybiochanin A) showed strong antioxidant activities. • Pharmacologic Activities: Study on pharmacologic activities of Compound Salvia Plebeia Granules (CSPG) long used for treating UTIs showed a dose-related diuretic effect, antipyretic, antiblastic, and anti-inflammatory effects. Results support its folkloric use on treating urinary tract infections. • Chemical Constituents: Study on whole plant of Salvia plebeia yielded nine compounds: ß-sitosterol, hispidulin, carnosol, rosmadial, ursolic acid, pectolinarigenin, epirosmanol, caffeic acid methyl ester and scopoletin. 8 and 9 were reported for Salvia genus for the first time and 3-7 from S. plebeia for the first time. • New Phenylfutanone Glucoside: Study yielded a new phenylbutanone glucoside, salviaplebeiaside, along with two known phenolic compounds, rosmarinic acid methyl ester and luteolin-7-O-ß-D-glucoside. • Hepatoprotective: Study evaluated the hepatoprotective effects of “Chhit-Chan-Than,” a Taiwan herbal remedy believed to have anti-inflammatory and detoxification activities, and used in the treatment of hepatitis. The crude extracts of the three herbal components – Salvia plebeia, O gratissimum and O basilicum – were studied. Results showed that S. plebeia was the most potent of the three crude extracts, protecting the liver against CCl4-intoxication and D-GaIN-induced hepatotoxicity.
The information presented herein is intended for educational purposes only. Individual results may vary, and before using any supplements, it is always advisable to consult with your own health care provider.
When Canadian citizens Nadine Artemis and Ron Obadia took a family vacation, it ended with them being led through Toronto’s airport in handcuffs, locked up and separated from their baby.
Police told them they could be facing years in prison for exporting narcotics.
Two and a half pounds of material found in their carry-on bag had tested positive for hashish. But they didn’t have drugs. They had chocolate. So far, the couple’s legal bills have topped $20,000.
The couple was caught up in what civil libertarians say is a growing problem — the use of unreliable field drug-test kits as the basis to arrest innocent people on illegal drug charges.
The kits, which are used by most every police department in the U.S., and by federal agents in Customs at the nation’s borders, use powerful acids that react with the substance in a plastic pouch. If the liquid turns a certain color, it is a considered a positive result.
A positive result generally leads to an arrest.
But a number of legal products and plants test positive:
Nosebleeds or Epistaxis are more often annoying than a serious health threat, although they can indicate the presence of other underlying illnesses.Most nosebleeds can be treated at home. They are messy and can be embarrassing, but most do not need professional medical attention. It is the relatively common occurrence of hemorrhage from the nose, usually noticed when the blood drains out through the nostrils. There are two types: anterior (the most common), and posterior (less common, more likely to require medical attention). Sometimes in more severe cases, the blood can come up the nasolacrimal duct and out from the eye. Fresh blood and clotted blood can also flow down into the stomach and cause nausea and vomiting. It accounts for only 0.001% of all deaths in the U.S.
What are they?
Most nosebleeds start in the lower part of the septum, the semi-rigid wall that separates the two channels of the nose.It contains blood vessels that can be broken by a blow to the nose or the edge of a sharp fingernail.With these nosebleeds – known as anterior nosebleeds – bleeding can occur from one side of the nose (epistaxis) or both (epistaxis bilateral).They can usually be treated easily at home and do not require medical attention.More rarely, posterior nosebleeds start when bleeding begins high and deep within the nose.Blood flows down the back of the mouth and throat even when the patient is sitting up or standing.This more severe type of nosebleed needs immediate medical attention.
Causes: The cause of nosebleeds can generally be divided into two categories, local and systemic factors, although it should be remembered that a significant number of nosebleeds occur with no obvious cause.
* Anatomical deformities, such as septal spurs or Osler-Weber-Rendu Syndrome
* Chemical inhalant
* Inflammatory reaction (eg. acute respiratory tract infections, chronic sinusitis, allergic rhinitis and environmental irritants)
* Foreign bodies
* Intranasal tumors (Nasopharyngeal carcinoma in adult, and nasopharyngeal angiofibroma in adolescent males)
* Nasal prong O2 which tends to dry the nasal mucosa
* Nasal sprays, particularly prolonged or improper use of nasal steroids
* Surgery (such as septoplasty and endoscopic sinus surgery)
* Trauma (usually a sharp blow to the face)
* Low relative humidity of air breathed occurring especially during winter seasons.
* Otic barotrauma from descent in aircraft or scuba diving.
* Drugs – Aspirin, Fexofenadine/Allegra/Telfast, warfarin, ibuprofen, clopidogrel, isotretinoin, desmopressin and others
* Alcohol (due to vasodilation)
* Blood dyscrasias
* Heart failure (due to an increase in venous pressure)
* Hematological malignancy
* Infectious diseases
* Narcotics, particularly insufflated cocaine
* Vascular disorders
Nosebleeds are caused by the rupture of a small blood vessel called a capilliary in the nose.The most common cause of this is injury – a good bash to the nose will result in bleeding.
Nosebleeds are due to the rupture of a blood vessel within the richly perfused nasal mucosa . Rupture may be spontaneous or initiated by trauma. An increase in blood pressure (eg due to general hypertension) or local blood flow (for example following a cold or infection) will increase the likelihood of a spontaneous nosebleed. Anticoagulant medication and disorders of blood clotting can promote and prolong bleeding. Spontaneous epistaxis is more common in the elderly as the nasal mucosa (lining) becomes dry and thin and blood pressure tends to be higher. The elderly are also more prone to prolonged nose bleeds as their blood vessels are less able to constrict and control the bleeding. The vast majority of nose bleeds occur in the anterior (front) part of the nose from the nasal septum. This area is richly endowed with blood vessels (Kiesselbach’s plexus). This region is also known as Little’s area. Bleeding further back in the nose is known as a posterior bleed and is usually due to rupture of the sphenopalatine artery or one of its branches. Posterior bleeds are often prolonged and difficult to control. They can be associated with bleeding from both nostrils and with a greater flow of blood into the mouth.
The other main cause is dryness of the inside of the nose. A dry climate or heated indoor air irritates and dries out nasal membranes, causing crusts that may itch and then bleed when picked.
Other causes of nosebleeds are colds, high altitude, allergies and medications.Nosebleeds can also result from a calcium deficiency.Occasionally, nosebleeds may indicate other disorders such as bleeding disorders, cancer, high blood pressure or disease of the arteries.They can also indicate hereditary haemorrhagic telangiectasia, also known as Osler-Weber-Rendu syndrome.This is a disorder involving a vascular growth similar to a birthmark in the back of the nose.
Doctors advise people with lower-septum nosebleeds to sit up straight and pinch the nostrils together firmly for 10 minutes.An ice pack can also be applied to the nose and cheeks.The pressure should then be relieved to see if the nose is still bleeding.If it is, patients are advised to pinch the nostrils for another 10 minutes.
If the nosebleed was caused by atmospheric dryness, the patient should breathe steamy air. After bleeding stops, petroleum jelly can be applied just inside the nose to prevent further bleeding.
Once bleeding has stopped, the sufferer should avoid any strenuous activity for 12 hours. Nor should they blow their nose, as this may dislodge blood clots and cause bleeding to start again.If bleeding does not stop after 30 minutes of direct pressure, patients should see a doctor.If blood runs down the back of the throat when pressure is applied to the nose, it could be a higher-septum nosebleed and require a visit to the doctor.Patients should also seek professional help if nosebleeds occur more than once a week.
The flow of blood normally stops when the blood clots, which may be encouraged by direct pressure applied by pinching the soft fleshy part of the nose. This applies pressure to Little’s area, the source of the majority of nose bleeds and promotes clotting. Pressure should be firm and be applied for at least 10 minutes while keeping the head in the neutral position and spitting out any blood which flows into the mouth. There is no benefit to pinching the bridge of the nose or to tilting the head backwards or forwards. Swallowing excess blood can irritate the stomach and cause vomiting. Local application of an ice pack to the forehead or back of the neck or sucking an ice cube has seen widespread practice, but has been shown to not have any statistically significant effects on nasal mucosal blood flow. In the past, it was commonly thought that the ice would help by promoting constriction of local blood vessels and thus reducing blood flow to slow down the bleed. Do not pack the nose with tissues or gauze.
The local application of a vasoconstrictive agent has been shown to reduce the bleeding time in benign cases of epistaxis. The drugs oxymetazoline or phenylephrine are widely available in over-the-counter nasal sprays for the treatment of allergic rhinitis, and may be used for this purpose.
Other products available promote coagulation include Coalgan (in Europe) or NasalCEASE (in the US). These are a calcium alginate mesh that is inserted in the nasal cavity to accelerate coagulation.
If these simple measures do not work then medical intervention may be needed to stop bleeding, possibly by an otolaryngologist (ENT doctor). In the first instance this can take the form of chemical cautery of any bleeding vessels or packing of the nose with ribbon gauze or an absorbent dressing (called Anterior nasal packing). Such procedures are best carried out by a medical professional. Chemical cauterisation is most commonly conducted using local application of silver nitrate compound to any visible bleeding vessel. This is a painful procedure and the nasal mucosa should be anaesthetised first, preferably with the addition of topical adrenaline to further reduce bleeding. If bleeding is still uncontrolled or no focal bleeding point is visible then the nasal cavity should be packed with a sterile dressing, which by applying pressure to the nasal mucosa will tamponade the bleeding point. Ongoing bleeding despite good nasal packing is a surgical emergency and can be treated by endoscopic evaluation of the nasal cavity under general anaesthesia to identify an elusive bleeding point or to directly ligate (tie off) the blood vessels supplying the nose. These blood vessels include the sphenopalatine, anterior and posterior ethmoidal arteries. More rarely the maxillary or external carotid artery can be ligated. The bleeding can also be stopped by intra-arterial embolization using a catheter placed in the groin and threaded up the aorta to the bleeding vessel by an interventional radiologist. Continued bleeding may be an indication of more serious underlying conditions.
Chronic epistaxis resulting from a dry nasal mucosa can be treated by spraying saline in the nose three times per day, lubricating the nose with ointment/creams like vasoline and installing a humidifer in the bedroom.
Application of a topical antibiotic ointment to the nasal mucosa has been shown to be an effective treatment for recurrent epistaxis. One study found it to be as effective as nasal cautery in the prevention of recurrent epistaxis in patients without active bleeding at the time of treatment (both had a success rate of approximately 50 percent.)
Nosebleeds are rarely dangerous unless prolonged and heavy. Nevertheless they should not be underestimated by medical staff. Particularly in posterior bleeds a great deal of blood may be swallowed and thus blood loss underestimated. The elderly and those with co-existing morbidities, particularly of blood clotting should be closely monitored for signs of shock.
Recurrent nosebleeds may cause anemia due to iron deficiency.
Cauterisation is the minor surgical procedure used to stop heavy nosebleeds.It involves destroying tissue with an electric current, a hot iron, or caustic chemicals.This seals the ruptured blood vessel and prevents further bleeding.This page contains basic information. If you are concerned about your health, you should consult a doctor.
Disclaimer: This information is not meant to be a substitute for professional medical advise or help. It is always best to consult with a Physician about serious health concerns. This information is in no way intended to diagnose or prescribe remedies.This is purely for educational purpose