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Vitamin B9 Treats Allergies, Asthma

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Folic acid, or vitamin B9, essential for the health of red blood cells and known to reduce the risk of spinal birth defects, may also  suppress allergic reactions and lessen the severity of allergy and asthma symptoms.

Johns Hopkins scientists, who conducted the first ever study examining the link between blood levels of folate, the naturally occurring form of folic acid and allergies, said results add to mounting evidence that folate can help regulate inflammation.

Recent studies, including research from Hopkins, have found a link between folate levels and inflammation-mediated diseases, including heart disease.

Cautioning that its far too soon to recommend folic acid supplements to prevent or treat people with asthma and allergies, researchers emphasise that more research needs to be done to confirm their results, and to establish safe doses and risks.

Reviewing the medical records of more than 8,000 people aged between two and 85 years, investigators tracked the effect of folate levels on respiratory and allergic symptoms and on levels of IgE antibodies, immune system markers that rise in response to an allergen.

People with higher blood levels of folate had fewer IgE antibodies, fewer reported allergies, less wheezing and a lower likelihood of asthma, researchers report.

“Our findings are a clear indication that folic acid may indeed help regulate immune response to allergens, and may reduce allergy and asthma symptoms,” said lead investigator Elizabeth Matsui.

“But we still need to figure out the exact mechanism behind it, and to do so we need studies that follow people receiving treatment with folic acid, before we even consider supplementation with folic acid to treat or prevent allergies and asthma.”

The current recommendation for daily dietary intake of folic acid is 400 micrograms for healthy men and non-pregnant women. Many cereals and grain products are already fortified with folate. Folate is also found naturally in green, leafy vegetables, beans and nuts, said a Hopkins release.

The study appeared online in the Journal of Allergy & Clinical Immunology.

Sources: The Times Of India

 
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Vitamin B1 Can Reverse Kidney Damage

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Vitamin B1 can reverse early kidney disease in people with type-2 diabetes, a study by British researchers has shown.
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The team from Warwick University tested the effect of vitamin B1 (thiamine), which is found in meat, yeast and grain, on 40 patients from Pakistan, BBC News website reported on Monday.

The treatment stopped the loss of a key protein in the urine, the journal Diabetologia reports. Charity Diabetes UK called the results “very promising” — but said it was too early for any firm conclusions.

The latest findings build on earlier work by the same team, showing that many diabetes patients have a deficiency of thiamine.

Sources: The Times Of India

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Vegetarians Prone to Strokes

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Strokes are the second most common cause of deaths and the commonest cause of severe disability.
Now a study has shown that deficiency of Vitamin B12, usually seen in vegetarians, can predispose a person to strokes much more than the usual risk factors — diabetes and hypertension.

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“While 20% of Indians suffer from diabetes and high BP,” says Dr Arun Garg, consultant neurologist, Max Hospitals, “incidence of homocysteinemia (increased levels of homocysteine, an amino acid) caused by vitamin B12 deficiency, is 70%. This is seen more among vegetarians as this vitamin is mainly found in meat and milk, if it’s neither boiled nor pasteurised.” In fact, deficiency of vitamins B12, B6 and folate causes two-thirds of strokes.

This risk is four times higher in vegetarians. As folate is found in vegetables and fruits, its deficiency is rare among Indians, but that of vitamin B12 is common.

Normal levels of homocysteine are 5-15 micromol per litre. Increased levels heighten the chances of blood clotting, which can lead to decrease in blood supply to the brain, causing a stroke. Studies have found high levels of homocysteine in over 80% of stroke patients. Even a rise of five micromol increases the risk of stroke by two times.

The link between strokes and vegetarianism was confirmed in a five-year study by Garg and Dr A K Jain, neurologist, Jain Neuro Centre, in two Max hospitals and this Centre. From 2003, 4,680 OPD patients were screened for vitamin B12 and homocysteine levels. Those with a history of stroke, heart disease, diabetes, chronic renal, liver problems, alcoholics and those on vitamin supplements were excluded. Most had vague complaints — tingling, numbness, chronic headaches and depressive symptoms like sleeplessness and fatigue.

It was found that 60% patients had vitamin B12 levels below 400 pg/ml and 38.9% had less than 200 pg/ml. Homocysteine levels were high (over 15 micromol/l) in 36%. And out of these, over 80% were either strict vegetarians or took non-vegetarian food less than once a week. This showed the co-relation between vegetarians and strokes.

To confirm the study, 418 ischemic stroke patients between 30-85 years admitted during the same period were analysed. It was found that homocysteine levels were high (over 15 micromol/l) in 77.5% of the patients showing vitamin deficiency can result in strokes. The effects of a stroke are serious and sometimes fatal — paralysis, loss of speech and vision, unsteadiness, double vision or even unconsciousness.

Dr Vinay Goyal, associate professor, neurology, AIIMS, says, “It’s true that vegetarians have less vitamin B12 as compared to non-vegetarians. This has been proven in Indian Americans, Germans, and Chinese/Singaporeans.”

Prevention would cost less than Rs 10 per day, says Garg. All one has to do is take prescribed doses of vitamin B12 and B6 and folic acid. These are shown to reduce homocysteine level by 38% and the risk of stroke by 20-30%. Goyal says, “Vitamin B12 is also there in soyabean, legumes, dairy products, cottage cheese, etc.” Garg and Jain gave vegetarian patients in their study daily vitamin supplements.

Their symptoms disappeared completely after 3-6 months of therapy. Vegetarians with vitamin B12 deficiency need life-long treatment. A dose of 1-1.5 mg/day is required, says Garg. The government too should fortify food with it, much like iodized salt. Also, as India has a high proportion of vegetarians, screening should be done. So get going to quell that stroke of bad luck.

Sources: The Times Of India

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Beauty of the Beetroot

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Scientists have discovered that beetroot has a remarkable effect on lowering blood pressure. Maria Fitzpatrick tries a medically approved new juice...

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Have you ever considered swapping your morning glass of fresh orange for freshly squeezed beetroot? Thought not – but in light of a remarkable discovery, it may be worth downing the inky, purple-red stuff with your cornflakes. And, thanks to the launch this month of a scrumptious new juice, getting your daily dose won’t require a pinch of the nose or scrubbing stubborn, deep purple stains off your chopping board.

Earlier this year, scientists at Barts and the London School of Medicine found that beetroot juice can have as great an effect on blood pressure as conventional drugs.

Led by Professor Amrita Ahluwalia of the William Harvey Research Institute – the renowned pharmacology centre that discovered how aspirin can prevent heart attacks and strokes – the research team found that just three hours after drinking 500ml of the juice (the equivalent of eating five medium-sized beetroots) there was a significant decrease in volunteers’ blood pressure. The remarkable effects were still noticeable 24 hours later.

That such an inexpensive and bounteous vegetable may lower blood pressure makes beetroot worthy of its new-found status as the first “super-root”. However, the woody consistency, off-putting earthy aroma and overly sweet taste (delete as applicable), of its raw juice have long prevented more of us taking a glug – which is a shame, given that one in three adults in the UK now suffers from hypertension and could benefit from a regular 250ml dose, the equivalent of an average glass.

According to the Blood Pressure Association, a third of sufferers don’t even realise they have the condition, which results in an estimated 350 “preventable” strokes or heart attacks every day.
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So how does beetroot work in the body? Like other superfoods, it has antioxidants in abundance, and is rich in iron, boron and folic acid. Betanene, which gives it its deep colour, is even more potent an antioxidant than polyphenols, the plant chemicals thought to be a key reason for people whose diets are rich in leafy vegetables having lower blood pressure.

But, says Professor Ben Benjamin, a consultant in Acute Medicine at the Peninsula Medical School in Plymouth and member of the research team, it is beetroot’s capacity to absorb and store exceptionally high levels of nitrate that earns it the super-root title. Nitrates are nutrients found in soil which all plants need to build protein, and which the body harnesses in its battle against blood pressure.

“When nitrate is present in high concentration in saliva, bacteria on the tongue converts it into a more reactive chemical, nitrite,” Prof Benjamin explains. “When the nitrite is swallowed, it is easily converted into nitric oxide, a chemical which is continually produced by our blood vessels to make them relax and hence keep blood pressure low. So dramatically increasing the levels of nitrate with beetroot juice increases this effect.”

Along with its anti-hypertensive effects, the study also found that the high levels of nitrates in beetroot juice work like aspirin does to prevent blood clots, and help to protect the lining of the blood vessels.

So encouraged were researchers by the magnitude of the blood pressure effect that they approached a Suffolk-based natural drinks company to produce a bottled beetroot juice that would make it easy for people to introduce the root into their diet.

The resulting juice, HeartBeet, is certainly palatable, and definitely good for you. A “no bits” blend of crushed organic roots, with a touch of apple juice (10 per cent) to balance out the taste, it is now on sale in selected Holland & Barrett stores. Unlike other juices already available, seven per cent of its proceeds will go directly back into funding cardiovascular research.

It’s rare for the medical community to put its weight so boldly behind the power of nature over pharmacology. According to Prof Benjamin, it is testament to the importance of the findings, which he believes could lead the way to proving that high blood pressure can be treated by altering diet alone, and with fewer – if any – conventional drugs.

“Currently, treatment for high blood pressure involves a cocktail of aspirin, statins, beta blockers, and angiotensin converting enzyme (ACE) inhibitors. Many people really don’t like taking all the tablets, especially since they often don’t feel unwell, and the treatment is essentially lifelong.”

One patient with high blood pressure, 60-year-old David Kelsall from Stoke-on-Trent, is already reaping the rewards of drinking a glass of beetroot juice a day. “I discovered that my blood pressure was higher than normal when my doctor was testing for something else,” he says. “It was 165/90mmHg – not life-threateningly serious, but none the less I was anxious to do something about it.”

Before committing to medication, he decided to give beetroot juice a try. “I drank three bottles of liquidised beetroot a week. Less than four weeks after the first test, I had my blood pressure taken again, and it had already levelled out to 150/90mmHg.” (A normal blood pressure reading would be in the range of 120/80mmHg.) “Now, a few months later, it is under control and normal. I am still drinking the juice, and I’m going to continue doing so. It may not help everyone, but it’s helped me.”

A growing body of research around the world suggests that the crucial nitrates in beetroot may also contribute to protecting us against other diseases, including infections and stomach ulcers – yet more reason to drink up. Having established a connection with blood pressure, scientists are now assessing just how much – or, rather, how little – of the juice is required for it to be effective.

If nothing else, beetroot’s health credentials give us all a reason to be smug: for once, the British country garden has come up with a foodstuff that trumps those in the Mediterranean “wonder diet”. And right now is the perfect time to grow your own. Beetroot seeds won’t germinate in temperatures below 7°C, or when there’s any inkling of ground frost, so early- to mid-summer is ideal to start planting. It can take as little as 10 weeks for a crop to mature, so you could be serving beetroot juice at your final summer barbecue of the year. We should all drink to that!
# HeartBeet organic beetroot juice (£1.49 for 25cl) is available from major Holland & Barrett stores (0870 606 6605, www.hollandandbarrett.com). For more details, call 01473 890111 or visit www.heartbeet.info

Sources: Telegraph.co.uk

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Meditation News on Health & Science

Meditation Can Keep BP In Control

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Meditation is not only a stress buster, it also helps in regulating high blood pressure with an added benefit of bypassing possible side effects and hazards of anti-hypertension drugs, says a new study.

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In the new meta-analysis, researchers from University of Kentucky conducted nine randomized, controlled trials with Transcendental Meditation as a primary intervention for hypertensive patients.
Transcendental Meditation among Brazil Police & Military

The findings revealed that practicing Transcendental Meditation led to approximate reduction of 4.7 mm systolic blood pressure and 3.2 mm diastolic blood pressure.

Dr. James W. Anderson, lead author and professor of medicine at the University Of Kentucky College Of Medicine, insisted that reduction the blood pressure could significantly reduce the risk of atherosclerotic cardiovascular disease without the side effects of drugs.

“Adding Transcendental Medication is about equivalent to adding a second antihypertension agent to one’s current regimen only safer and less troublesome,” he said

Sources: The Times Of India

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